Diuretics combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Failure Other Serious 10/20/2006 88 Female 1/31/2007 Physician Australia
Primary
Concomitant
Convulsion Other Serious 3/12/2007 Male 149 lb 3/27/2007 Consumer United States
Primary
Secondary
Concomitant
Convulsion Other Serious 3/12/2007 Male 149 lb 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 10/20/2006 88 Female 5/29/2007 Physician Australia
Primary
Secondary
Concomitant
Middle Insomnia 1/1/2007 69 Male 142 lb 4/12/2007 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/8/2007 75 Male 10/30/2007 Physician Netherlands
Primary
Concomitant
Orthostatic Hypotension Other Serious 8/8/2007 75 Male 11/19/2007 Physician Netherlands
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 11/1/2006 65 Male 3/9/2009 Physician United States
Primary
Concomitant
Tooth Infection Other Serious Female 4/28/2009 United States
Primary
Concomitant
Myoclonus Other Serious 79 Male 5/6/2009 Physician United States
Primary
Concomitant
Pulmonary Toxicity Other Serious 62 Male 5/29/2009
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 85 Female 7/30/2009 Physician Finland
Primary
Secondary
Concomitant
Hypovolaemia Life Threatening 5/1/2009 Female 8/10/2009 Physician Norway
Primary
Secondary
Concomitant
Pain Hospitalization 76 Female 12/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypertensive Crisis Other Serious 10/30/2009 Male 247 lb 12/31/2009 Physician Germany
Primary
Secondary
Concomitant
Hypertensive Crisis Other Serious 3/30/2009 Female 165 lb 1/19/2010 Physician Germany
Primary
Secondary
Concomitant
Somatoform Disorder Hospitalization 1/23/2009 Male 1/22/2010 Physician Germany
Primary
Concomitant
Head Injury Death 9/9/2009 Male 243 lb 2/10/2010 Physician Germany
Primary
Concomitant
Wound Other Serious 9/1/2009 Male 218 lb 3/9/2010 Physician Germany
Primary
Concomitant
Hypertensive Crisis Other Serious 10/30/2009 Male 247 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Hypertensive Crisis Other Serious 10/30/2009 Male 247 lb 3/22/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Other Serious 9/1/2009 60 Male 218 lb 4/2/2010 Physician Germany
Primary
Concomitant
Hypertensive Crisis Other Serious 10/30/2009 77 Male 247 lb 4/6/2010 Physician Germany
Primary
Secondary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 4/19/2010 Physician Germany
Primary
Secondary
Concomitant
Vascular Graft Other Serious 5/5/2009 71 Female 205 lb 4/19/2010 Physician Germany
Primary
Concomitant
Neutropenia Hospitalization 4/26/2010 73 Female 5/11/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 2/19/2009 76 Male 212 lb 5/19/2010 Physician Germany
Primary
Secondary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 5/29/2010 Physician Germany
Primary
Secondary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 6/3/2010 Physician Germany
Primary
Secondary
Concomitant
Orthostatic Intolerance Other Serious 7/30/2009 72 Female 181 lb 6/10/2010 Physician Germany
Primary
Secondary
Concomitant
Stent Placement Other Serious 1/31/2010 63 Male 205 lb 6/11/2010 Physician Germany
Primary
Secondary
Concomitant
Coronary Artery Stenosis Other Serious 7/28/2009 67 Female 196 lb 7/26/2010 Physician Germany
Primary
Concomitant
Hypertensive Crisis Other Serious 3/30/2009 80 Female 165 lb 8/27/2010 Physician Germany
Primary
Secondary
Concomitant
Uterine Cancer Death Female 161 lb 9/3/2010 Physician Germany
Primary
Concomitant
Somatoform Disorder Hospitalization 1/23/2009 61 Male 240 lb 9/9/2010 Physician Germany
Primary
Concomitant
Respiratory Arrest Other Serious 60 Male 9/14/2010 Germany
Primary
Concomitant
Respiratory Arrest Other Serious 60 Male 9/30/2010 Other Health Professional Germany
Primary
Concomitant
Respiratory Arrest Other Serious 60 Male 10/12/2010 Physician Germany
Primary
Concomitant
Renal Failure Chronic Hospitalization 2/8/2008 60 Female 280 lb 10/21/2010 Physician United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2010 51 Male 11/8/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 9/1/2010 75 Female 11/14/2010 Consumer United States
Primary
Concomitant
Hypertensive Crisis Other Serious 10/30/2009 77 Male 247 lb 11/30/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphoedema Hospitalization Female 12/7/2010 Physician Belgium
Primary
Concomitant
Respiratory Arrest Other Serious 60 Male 11/23/2010 Other Health Professional Germany
Primary
Concomitant
Lymphoedema Hospitalization Female 12/10/2010 Physician Belgium
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 9/1/2009 61 Female 12/14/2010 Physician Belgium
Primary
Concomitant
Electrocardiogram Qrs Complex Prolonged Death 4/15/2010 79 Male 370 lb 12/21/2010 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 3/16/2009 89 Male 178 lb 12/24/2010 United States
Primary
Concomitant
Dehydration Hospitalization 79 Female 1/5/2011 Consumer United States
Primary
Secondary
Concomitant
Oedema Hospitalization 9/1/2009 61 Female 2/4/2011 Physician Belgium
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 9/1/2009 61 Female 2/7/2011 Physician Belgium
Primary
Concomitant
Lymphoedema Hospitalization 9/1/2009 61 Female 2/8/2011 Physician Belgium
Primary
Concomitant
Vaginal Cancer Hospitalization 6/14/2010 80 Female 161 lb 3/14/2011 Physician Germany
Primary
Concomitant
Coronary Artery Disease Other Serious 6/3/2009 61 Male 203 lb 4/11/2011 Physician Germany
Primary
Concomitant
Dyspnoea Exertional Hospitalization 3/3/2009 65 Male 165 lb 5/20/2011 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/3/2009 65 Male 165 lb 5/20/2011 Physician Germany
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 6/3/2009 61 Male 203 lb 5/28/2011 Physician Germany
Primary
Concomitant
Mitral Valve Incompetence Other Serious 3/16/2009 89 Male 178 lb 5/31/2011 United States
Primary
Concomitant
Abdominal Pain Upper Hospitalization 2/8/2008 59 Female 280 lb 5/20/2011 Consumer United States
Primary
Concomitant
Hypertension Disability 8/23/2010 56 Male 287 lb 7/5/2011 Physician Germany
Primary
Secondary
Concomitant
Left Ventricular Hypertrophy Other Serious 12/10/2008 78 Male 229 lb 7/13/2011 Physician Germany
Primary
Concomitant
Atrial Flutter Hospitalization 11/9/2009 66 Male 168 lb 7/13/2011 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Exertional Hospitalization 3/3/2009 65 Male 165 lb 7/14/2011 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 3/3/2009 65 Male 165 lb 7/14/2011 Physician Germany
Primary
Secondary
Concomitant
Refractory Anaemia Disability 8/23/2010 56 Male 287 lb 7/15/2011 Physician Germany
Primary
Secondary
Concomitant
Myocardial Infarction 5/13/2011 76 Female 159 lb 7/20/2011 Physician Austria
Primary
Concomitant
Memory Impairment Hospitalization 7/12/2011 71 Female 177 lb 7/29/2011 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 9/1/2009 72 Male 161 lb 8/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/16/2011 76 Female 159 lb 8/19/2011 Physician Austria
Primary
Concomitant
Drug Dose Omission Hospitalization 6/1/2011 71 Female 177 lb 8/23/2011 Consumer United States
Primary
Concomitant
Vertigo Other Serious 3/3/2009 65 Male 165 lb 9/16/2011 Physician Germany
Primary
Secondary
Concomitant
Hypertension Other Serious 76 Female 9/28/2011 Physician Brazil
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 11/9/2009 66 Male 168 lb 10/4/2011 Physician Germany
Primary
Secondary
Concomitant
Drug Dose Omission Hospitalization 6/1/2011 71 Female 177 lb 10/5/2011 Consumer United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 9/1/2010 75 Female 10/18/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious 8/1/2011 63 Male 10/27/2011 Physician Germany
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 10/3/2011 68 Male 161 lb 11/16/2011 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2006 52 Male 210 lb 12/5/2011 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2006 52 Male 210 lb 12/5/2011 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/20/2010 Female 241 lb 1/9/2012 Consumer Germany
Primary
Concomitant
Anaemia Hospitalization 4/5/2008 64 Male 1/16/2012 Physician Canada
Primary
Concomitant
Lung Disorder Death 5/25/2010 78 Male 1/16/2012 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 1/8/2010 75 Male 1/16/2012 Physician United States
Primary
Concomitant
Bipolar I Disorder Hospitalization 3/9/2009 75 Male 1/16/2012 Physician United States
Primary
Concomitant
Myalgia Hospitalization 4/24/2008 70 Female 1/16/2012 Physician United States
Primary
Concomitant
Myocardial Infarction Death 11/22/2007 63 Male 1/16/2012 Physician United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 2/7/2008 64 Male 1/16/2012 Physician United States
Primary
Concomitant
Haematuria Hospitalization 10/27/2006 79 Female 1/16/2012 Physician United States
Primary
Concomitant
Influenza Death 12/5/2009 67 Male 1/16/2012 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/28/2008 76 Male 1/16/2012 Physician United States
Primary
Concomitant
Anaemia Hospitalization 12/6/2009 76 Male 1/16/2012 Physician Canada
Primary
Concomitant
Gastroenteritis Hospitalization 11/13/2009 48 Male 1/16/2012 Physician United States
Primary
Concomitant
Neoplasm Malignant Hospitalization Male 1/16/2012 Physician Canada
Primary
Concomitant
Neoplasm Malignant Death 2/10/2011 81 Male 1/16/2012 Physician Canada
Primary
Concomitant
Hypotension Hospitalization 4/12/2008 64 Male 1/16/2012 Other Health Professional Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 3/18/2010 82 Male 1/16/2012 Physician Canada
Primary
Concomitant
Neoplasm Malignant Death 4/15/2010 66 Male 1/16/2012 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/4/2008 72 Male 1/16/2012 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 12/20/2009 73 Female 1/16/2012 Physician United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 2/15/2008 78 Male 1/16/2012 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/6/2011 72 Male 1/16/2012 Physician United States
Primary
Concomitant
Death Death 6/25/2010 70 Male 1/16/2012 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 1/27/2010 85 Male 1/16/2012 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 2/12/2011 67 Male 1/16/2012 Physician United States
Primary
Concomitant
Osteoarthritis Hospitalization 10/1/2009 72 Male 1/16/2012 Physician United States
Primary
Concomitant
Death Death 1/1/2010 74 Male 1/16/2012 Physician United States
Primary
Concomitant
Angina Pectoris Hospitalization 4/27/2006 65 Male 1/16/2012 Physician Canada
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 11/2/2008 67 Male 1/16/2012 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 5/8/2010 65 Female 1/16/2012 Physician United States
Primary
Concomitant
Asthma Hospitalization 2/25/2007 82 Female 1/16/2012 Physician United States
Primary
Concomitant
Bipolar I Disorder Hospitalization 3/9/2009 75 Male 1/17/2012 Physician United States
Primary
Concomitant
Death Death 1/1/2010 74 Male 1/17/2012 Physician United States
Primary
Concomitant
Renal Failure Life Threatening 7/7/2011 66 Male 192 lb 1/27/2012 Physician Germany
Primary
Secondary
Concomitant
Blood Triglycerides Increased Life Threatening 7/7/2011 66 Male 192 lb 2/3/2012 Physician Germany
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 4/9/2011 91 Female 157 lb 2/7/2012 Physician Germany
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 6/28/2011 72 Female 187 lb 2/11/2012 Physician Germany
Primary
Concomitant
Hypomagnesaemia Hospitalization 8/12/2008 63 Male 174 lb 2/13/2012 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 9/22/2011 62 Male 2/21/2012 Physician Israel
Primary
Concomitant
Blood Sodium Decreased Other Serious 9/14/2011 81 Female 2/29/2012 Physician Germany
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 4/9/2011 91 Female 157 lb 3/1/2012 Physician Germany
Primary
Concomitant
Melaena Life Threatening 9/22/2011 62 Male 3/2/2012 Physician Israel
Primary
Concomitant
Malaise Hospitalization 5/15/2010 71 Female 3/2/2012 Physician Belgium
Primary
Concomitant
Fluid Retention Hospitalization 9/1/2010 75 Female 3/2/2012 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 6/28/2011 72 Female 187 lb 3/7/2012 Physician Germany
Primary
Concomitant
Anaemia Life Threatening 9/22/2011 62 Male 3/19/2012 Physician Israel
Primary
Concomitant
Renal Failure Hospitalization Female 121 lb 3/28/2012 Physician Germany
Primary
Secondary
Concomitant
Syncope Other Serious 2/8/2012 66 Male 234 lb 3/29/2012 Physician Germany
Primary
Concomitant
Arteriosclerosis Hospitalization 8/28/2011 65 Male 218 lb 3/28/2012 Physician Germany
Primary
Concomitant
Angina Pectoris Other Serious 12/10/2008 78 Male 229 lb 4/5/2012 Physician Germany
Primary
Concomitant
Blood Potassium Increased Other Serious 4/27/2011 82 Male 4/13/2012 Physician Germany
Primary
Concomitant
Nausea Other Serious 1/1/2009 75 Female 4/16/2012 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/3/2011 68 Male 161 lb 4/18/2012 Physician Germany
Primary
Secondary
Concomitant
Haemoptysis Other Serious 9/22/2011 62 Male 4/19/2012 Physician Israel
Primary
Concomitant
Angina Pectoris Other Serious 8/23/2010 56 Male 287 lb 5/4/2012 Physician Germany
Primary
Secondary
Concomitant
Blood Pressure Diastolic Decreased Hospitalization 8/23/2010 56 Male 287 lb 5/4/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Congestive Life Threatening 9/22/2011 62 Male 5/7/2012 Physician Israel
Primary
Concomitant
Cataract Other Serious 9/22/2011 62 Male 5/9/2012 Physician Israel
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 4/27/2011 82 Male 181 lb 5/10/2012 Physician Germany
Primary
Secondary
Concomitant
Electrocardiogram Qrs Complex Prolonged Other Serious 8/23/2010 56 Male 287 lb 5/14/2012 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 8/23/2010 56 Male 287 lb 5/14/2012 Physician Germany
Primary
Secondary
Concomitant
Wegener's Granulomatosis Other Serious 9/22/2011 62 Male 5/21/2012 Physician Israel
Primary
Concomitant
Cardiac Failure Hospitalization 1/11/2011 82 Male 234 lb 6/5/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/11/2011 82 Male 234 lb 6/5/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/11/2011 82 Male 234 lb 6/15/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/11/2011 82 Male 234 lb 6/15/2012 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/24/2011 77 Male 207 lb 7/24/2012 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 1/24/2011 77 Male 207 lb 7/25/2012 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Hospitalization 7/30/2012 63 Female 5/21/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2012 59 Female 220 lb 11/28/2012 Other Health Professional Us
Primary
Concomitant
Panic Reaction Other Serious 75 Female 11/7/2012 Other Health Professional Gb
Primary
Concomitant

Drug Data