Cyanocobalamin combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
Hypotension Hospitalization 10/3/2005 79 Male 193 lb 10/5/2005 Pharmacist United States
Primary
Secondary
Concomitant
Nausea Hospitalization 11/20/2005 57 Male 144 lb 12/14/2005 Pharmacist United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/13/2005 Male 171 lb 11/18/2005 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 3/15/2006 72 Male 215 lb 3/22/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2005 Male 5/15/2006 Physician Canada
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 1/20/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/19/2006 62 Male 180 lb 6/21/2006 United States
Primary
Concomitant
Splenomegaly Death 7/1/2006 36 Female 7/28/2006 Physician Philippines
Primary
Concomitant
Vision Blurred Other Serious 8/1/2005 73 Male 7/25/2006 Canada
Primary
Concomitant
Splenomegaly Other Serious 7/1/2006 36 Female 8/3/2006 Physician Philippines
Primary
Concomitant
Small Intestinal Haemorrhage Hospitalization 6/12/2006 64 Male 198 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 4/11/2006 78 Male 186 lb 6/23/2006 Pharmacist United States
Primary
Concomitant
Erysipeloid Other Serious 1/1/2006 72 Male 187 lb 8/11/2006 Physician France
Primary
Concomitant
Abdominal Discomfort Other Serious 7/10/2006 78 Male 180 lb 7/10/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 7/18/2006 74 Male 341 lb 7/18/2006 Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 8/7/2006 88 Male 169 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 8/7/2006 85 Female 164 lb 11/11/2006 Physician Germany
Primary
Concomitant
Lip Disorder Other Serious 6/6/2006 65 Male 131 lb 7/28/2006 Physician United States
Primary
Concomitant
Urinary Retention Death 10/14/2006 69 Female 11/27/2006 Other Health Professional Sweden
Primary
Concomitant
Thrombosis Hospitalization 8/15/2006 84 Male 128 lb 12/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 1/1/2005 71 Male 1/2/2007 United Kingdom
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 9/21/2006 Male 150 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Anaemia Other Serious 10/19/2006 83 Male 175 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Femur Fracture Other Serious 10/15/2005 Female 3/2/2007 Other Health Professional Sweden
Primary
Concomitant
Treatment Noncompliance Hospitalization 3/15/2007 74 Male 272 lb 3/27/2007 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 3/18/2007 81 Male 191 lb 4/4/2007 Pharmacist United States
Primary
Concomitant
Oral Pain Required Intervention 1/22/2007 76 Male 190 lb 2/7/2007 Physician United States
Primary
Concomitant
Streptococcal Infection Hospitalization 5/6/2007 Male 216 lb 5/9/2007 United States
Primary
Secondary
Concomitant
Hospitalisation Hospitalization Female 7/13/2007 Canada
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 5/27/2007 76 Male 177 lb 8/6/2007 Physician United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 5/27/2007 76 Male 177 lb 8/6/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/19/2007 68 Male 8/7/2007 Pharmacist United States
Primary
Concomitant
Drug Interaction Other Serious 64 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Panic Attack Hospitalization 2/10/2007 74 Male 216 lb 8/17/2007 United States
Primary
Concomitant
Chest Pain Hospitalization 7/7/2007 Female 155 lb 8/29/2007 Canada
Primary
Concomitant
Fluid Retention Other Serious 10/1/2007 Female 255 lb 10/23/2007 United States
Primary
Concomitant
Nausea Hospitalization 5/1/2007 77 Male 216 lb 10/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/29/2007 Male 10/30/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2007 Female 11/2/2007 Other Health Professional France
Primary
Concomitant
Interacting
Weight Decreased Other Serious 7/1/2007 Female 11/14/2007 Other Health Professional France
Primary
Concomitant
Interacting
Wrong Drug Administered Death 12/8/2007 Male 155 lb 12/14/2007 Other Health Professional United States
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 1/24/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/16/2008 77 Female 1/28/2008 Pharmacist Japan
Primary
Concomitant
Urine Output Decreased Hospitalization 1/16/2008 77 Female 117 lb 1/30/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Panic Attack Hospitalization 2/10/2007 74 Male 216 lb 2/6/2008 United States
Primary
Concomitant
Urine Output Decreased Hospitalization 1/16/2008 77 Female 117 lb 2/20/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 2/28/2008 Other Health Professional Sweden
Primary
Concomitant
Hyperkalaemia Hospitalization 9/4/2007 Female 2/28/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/29/2007 60 Male 203 lb 10/30/2007 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 9/4/2007 Female 3/17/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 3/25/2008 Other Health Professional Sweden
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 4/18/2008 Other Health Professional Sweden
Primary
Concomitant
Hypoglycaemia Hospitalization 3/25/2008 75 Female 5/16/2008 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 5/16/2008 Other Health Professional Sweden
Primary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Mood Altered 3/1/2008 Male 180 lb 6/12/2008 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 6/20/2008 Other Health Professional Sweden
Primary
Concomitant
Hypoglycaemia Hospitalization 3/25/2008 75 Female 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 6/21/2008 Male 7/7/2008 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Hospitalization 1/16/2008 77 Female 117 lb 7/16/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Pruritus Female 8/27/2008 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 8/28/2008 Other Health Professional Sweden
Primary
Concomitant
Muscle Disorder 7/16/2008 Female 120 lb 9/12/2008 Physician United States
Primary
Concomitant
Swollen Tongue Hospitalization 6/21/2008 Male 9/19/2008 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2006 Female 9/30/2008 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 10/1/2008 Other Health Professional Sweden
Primary
Concomitant
Wheezing Other Serious 1/1/2008 Male 150 lb 10/28/2008 Consumer Brazil
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2008 Male 150 lb 11/4/2008 Consumer Brazil
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/10/2008 Female 176 lb 11/14/2008 Canada
Primary
Concomitant
Syncope Other Serious 10/1/2008 Female 120 lb 11/25/2008 Pharmacist United States
Primary
Concomitant
Dysphagia 9/11/2008 Male 331 lb 12/4/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 8/23/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Weight Decreased Female 161 lb 12/12/2008 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/25/2008 Male 185 lb 12/19/2008 Physician Denmark
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 12/31/2008 Other Health Professional Sweden
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 1/27/2009 Other Health Professional Sweden
Primary
Concomitant
Hallucination Other Serious 1/27/2009 85 Male 2/16/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 11/15/2008 Male 182 lb 2/12/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 2/4/2009 Male 110 lb 3/3/2009 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 3/4/2009 Other Health Professional Sweden
Primary
Concomitant
Ventricular Fibrillation Other Serious 2/4/2009 Male 110 lb 3/4/2009 Physician Japan
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 3/18/2009 Other Health Professional Sweden
Primary
Concomitant
Brain Stem Infarction Hospitalization 9/10/2006 46 Female 3/17/2009 Korea, Republic Of
Primary
Concomitant
Hemiparesis Hospitalization 7/8/2008 Male 206 lb 3/31/2009 Physician United States
Primary
Concomitant
Sepsis Death 77 Male 4/15/2009 Consumer United States
Primary
Secondary
Sepsis Death 75 Male 4/21/2009 Consumer United States
Primary
Concomitant
Sepsis Other Serious Male 4/21/2009 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2008 Male 4/21/2009 Other Health Professional Sweden
Primary
Concomitant
Nightmare 7/25/2007 58 Male 176 lb 12/19/2008 Pharmacist United States
Primary
Concomitant
Sepsis Death Male 4/23/2009 Physician United States
Primary
Secondary
Sepsis Hospitalization Male 4/23/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 75 Male 4/21/2009 United States
Primary
Concomitant
Sepsis Other Serious Male 4/30/2009 Consumer United States
Primary
Concomitant
Sepsis Death Male 304 lb 5/5/2009 Consumer
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 8/11/2008 Male 172 lb 4/2/2009 Consumer United States
Primary
Concomitant
Nephrolithiasis Hospitalization 4/10/2009 Male 290 lb 5/12/2009 Consumer United States
Primary
Concomitant
Sepsis Death 75 Male 5/19/2009 Consumer United States
Primary
Concomitant
Sepsis Death 77 Male 5/29/2009 Consumer United States
Primary
Secondary
Urine Output Decreased Hospitalization 7/19/2008 81 Male 145 lb 6/8/2009 United States
Primary
Secondary
Concomitant
Sepsis Death 12/18/2006 Male 6/29/2009 Physician United States
Primary
Secondary
Sepsis Death 75 Male 7/1/2009 Consumer United States
Primary
Secondary
Hemiparesis Hospitalization 7/8/2008 Male 206 lb 7/1/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 72 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 72 Female 8/5/2009 United States
Primary
Concomitant
Blood Glucose Increased Male 8/22/2009 United States
Primary
Concomitant
Lymphocyte Count Decreased Disability 1/4/2009 63 Male 154 lb 9/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 8/23/2009 72 Female 137 lb 9/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/8/2009 Male 234 lb 9/18/2009 Other Health Professional Italy
Primary
Concomitant
Pain In Extremity Other Serious 72 Female 9/23/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2004 49 Male 144 lb 9/23/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 5/8/2009 Male 234 lb 10/24/2009 Italy
Primary
Concomitant
Urine Output Decreased Hospitalization 7/19/2008 81 Male 145 lb 11/20/2009 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/13/2009 Male 12/2/2009 Physician United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 11/30/2009 Consumer United States
Primary
Concomitant
Hemiparesis Hospitalization 7/8/2008 Male 206 lb 12/1/2009 Physician United States
Primary
Concomitant
Parosmia Other Serious 11/11/2009 Female 193 lb 11/20/2009 Pharmacist United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 12/21/2009 Female 153 lb 12/22/2009 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/5/2009 74 Female 1/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 6/14/2009 Male 1/7/2010 Physician United States
Primary
Concomitant
Vascular Rupture Hospitalization 70 Female 1/7/2010 United States
Primary
Concomitant
Swelling 9/25/2009 Female 171 lb 10/13/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/16/2009 67 Male 216 lb 3/31/2010 Physician United States
Primary
Secondary
Concomitant
Serum Ferritin Increased 4/12/2010 Physician Germany
Primary
Concomitant
Respiratory Failure Hospitalization Male 146 lb 4/7/2010 Other Health Professional Germany
Primary
Concomitant
Dyspnoea Other Serious 10/1/2007 84 Female 4/13/2010 Lawyer United States
Primary
Concomitant
Toothache Other Serious 11/1/2009 70 Female 149 lb 4/26/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 7/1/1999 60 Female 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Amnesia Disability 12/12/2008 53 Male 161 lb 5/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Amnesia Disability 12/12/2008 53 Male 161 lb 5/11/2010 Other Health Professional
Primary
Concomitant
Vomiting Other Serious 12/23/2009 64 Male 5/14/2010 Other Health Professional Sweden
Primary
Concomitant
Hypertension Life Threatening 4/21/2010 62 Male 171 lb 5/19/2010 Physician Japan
Primary
Concomitant
Tuberculosis Hospitalization Male 146 lb 5/18/2010 Physician Germany
Primary
Concomitant
Amnesia Disability 12/12/2008 53 Male 161 lb 5/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 12/1/2009 72 Male 146 lb 5/27/2010 Physician Germany
Primary
Concomitant
Incoherent Hospitalization 5/12/2010 82 Male 6/11/2010 Consumer United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 6/11/2010 United States
Primary
Concomitant
Wound Dehiscence Life Threatening 2/2/2010 81 Female 196 lb 6/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 12/23/2009 64 Male 6/14/2010 Other Health Professional Sweden
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 6/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/11/2009 72 Male 146 lb 6/9/2010 Other Health Professional Germany
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2009 6/28/2010 Physician Germany
Primary
Concomitant
Hypertension Life Threatening 4/21/2010 62 Male 171 lb 7/1/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 9/11/2009 72 Male 146 lb 6/24/2010 Physician Germany
Primary
Concomitant
Vomiting Other Serious 7/1/1999 60 Female 7/12/2010 United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 1/16/2004 59 Male 7/14/2010 United States
Primary
Concomitant

Drug Data