Nicorandil combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
Pulmonary Fibrosis Death 8/25/2005 Female 1/20/2006 United Kingdom
Primary
Concomitant
Somnolence Hospitalization 6/28/2005 62 Male 141 lb 1/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Vesicular Other Serious 43 Male 2/2/2006 United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 8/25/2005 Female 148 lb 2/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2006 Male 4/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 6/2/2006 Consumer United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 2/7/2006 58 Male 196 lb 6/1/2006 United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Hospitalization 4/1/2006 74 Female 6/14/2006 Physician
Primary
Secondary
Concomitant
Sinus Headache Disability 5/4/2006 79 Male 212 lb 6/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Fall Hospitalization 5/22/2006 85 Female 6/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/17/2006 Other Health Professional Japan
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/26/2006 Other Health Professional Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/29/2006 83 Male 7/25/2006 United Kingdom
Primary
Concomitant
Myalgia Other Serious 5/9/2006 79 Male 182 lb 9/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 1/10/2006 63 Female 192 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 3/14/2005 Female 148 lb 12/15/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Hesitation Other Serious 10/30/2006 57 Male 1/15/2007 Consumer United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/3/2006 78 Male 1/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 1/10/2006 63 Female 192 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 3/1/2007 United Kingdom
Primary
Concomitant
Dystonia Hospitalization 1/3/2007 68 Female 4/3/2007 United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Death 11/17/2006 Female 106 lb 4/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dystonia Hospitalization 1/3/2007 68 Female 4/5/2007 United Kingdom
Primary
Secondary
Concomitant
Sleep Paralysis Other Serious 3/29/2007 182 lb 5/4/2007 Consumer United Kingdom
Primary
Concomitant
Humerus Fracture Hospitalization 4/15/2007 70 Female 5/8/2007 United Kingdom
Primary
Concomitant
Wheezing Other Serious 1/1/2007 Male 254 lb 5/17/2007 Physician United Kingdom
Primary
Concomitant
Vision Blurred Disability 3/21/2007 71 Female 6/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Paraesthesia Oral Other Serious 6/15/2007 57 Female 250 lb 7/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Necrosis Other Serious 6/25/2007 84 Male 7/26/2007 Australia
Primary
Concomitant
Muscle Necrosis Other Serious 6/25/2007 84 Male 7/31/2007 Australia
Primary
Concomitant
Angina Pectoris Disability 2/1/2007 62 Male 231 lb 8/10/2007 Consumer United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 8/5/2007 35 Female 294 lb 8/17/2007 Consumer United Kingdom
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 8/31/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/6/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/11/2007 89 Female 9/14/2007 Other Health Professional France
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 10/10/2007 Other Health Professional Australia
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 9/14/2007 75 Male 146 lb 11/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 11/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Life Threatening 9/14/2007 75 Male 146 lb 11/15/2007 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Tremor Life Threatening 9/14/2007 11/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Life Threatening 9/14/2007 75 Male 11/16/2007 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 11/1/2007 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death 10/31/2007 Female 183 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2007 Male 254 lb 12/17/2007 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 11/12/2007 61 Male 12/21/2007
Primary
Concomitant
Vomiting Hospitalization 11/15/2007 55 Female 287 lb 1/15/2008 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 1/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 2/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Necrosis Other Serious 6/25/2007 84 Male 1/29/2008 Australia
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/23/2008 47 Female 256 lb 2/19/2008 Physician United Kingdom
Primary
Concomitant
Tibia Fracture Hospitalization 9/8/2007 50 Male 249 lb 2/11/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 2/11/2008 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/23/2008 47 Female 256 lb 2/22/2008 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Life Threatening 77 Female 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 3/12/2008 4/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Death 4/10/2008 69 Female 207 lb 4/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Disease Progression Death 69 Female 208 lb 5/2/2008 Consumer United Kingdom
Primary
Concomitant
Depression Life Threatening 9/5/2005 5/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 5/5/2008 58 Male 5/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 5/10/2008 75 Male 6/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/1/2008 Female 199 lb 6/13/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 75 Male 6/16/2008 United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/7/2008 Female 207 lb 6/27/2008 Consumer United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious Male 304 lb 8/4/2008 Consumer United Kingdom
Primary
Concomitant
Incorrect Dose Administered Hospitalization 6/1/2008 Female 174 lb 8/22/2008 Physician United Kingdom
Primary
Concomitant
Large Intestine Perforation Hospitalization Male 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 6/6/2008 77 Male 180 lb 8/25/2008 United Kingdom
Primary
Concomitant
Multiple Myeloma Other Serious Male 304 lb 9/5/2008 Consumer United Kingdom
Primary
Concomitant
Large Intestine Perforation Hospitalization 12/1/2007 Male 9/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 9/29/2008 Male 267 lb 10/16/2008 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 82 Female 12/9/2008 Other Health Professional Japan
Primary
Concomitant
Rash Pruritic Other Serious 11/29/2008 Male 12/18/2008 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 76 Male 12/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Diabetes Mellitus Inadequate Control Other Serious 76 Male 12/30/2008 Physician United Kingdom
Primary
Secondary
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 146 lb 1/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 146 lb 1/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 7/1/2008 85 Female 117 lb 2/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 11/1/2006 85 Female 117 lb 1/27/2009 Other Health Professional
Primary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Skin Exfoliation Disability 1/12/2009 Male 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 77 Female 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fall Other Serious 12/31/2008 2/25/2009 France
Primary
Concomitant
Interacting
Tibia Fracture Other Serious 12/31/2008 2/27/2009 Other Health Professional France
Primary
Concomitant
Interacting
Urinary Tract Infection Life Threatening 77 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 12/31/2008 3/11/2009 Other Health Professional France
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 77 Female 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/11/2009
Primary
Secondary
Concomitant
Tibia Fracture Other Serious 12/31/2008 3/17/2009 Other Health Professional France
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 77 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2009 77 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 3/23/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 4/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sensory Disturbance Other Serious 11/17/2008 80 Male 4/17/2009 Physician
Primary
Concomitant
Rhabdomyolysis Other Serious 7/1/2008 85 Female 117 lb 4/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Syncope Hospitalization 1/6/2009 79 Female 5/1/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 1/29/2009 77 Male 5/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 3/16/2009 69 Male 165 lb 5/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 1/6/2009 79 Female 5/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myositis Hospitalization 1/17/2009 79 Female 5/1/2009
Primary
Secondary
Concomitant
Syncope Death 79 Female 5/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 5/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Thrombocytopenia Life Threatening 3/16/2009 69 Male 165 lb 5/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 3/16/2009 69 Male 5/14/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 5/27/2009 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 6/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 4/1/2008 85 Female 117 lb 7/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oesophagitis Other Serious 10/1/2008 77 Female 7/28/2009 United Kingdom
Primary
Concomitant
Sepsis Death 91 Female 8/3/2009 Consumer United Kingdom
Primary
Concomitant
Syncope Other Serious 5/26/2009 8/6/2009 Physician Italy
Primary
Concomitant
Sepsis Death 91 Female 8/6/2009 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 8/17/2009 Consumer United Kingdom
Primary
Concomitant
Urosepsis Death 91 Female 8/19/2009 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 8/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 8/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urosepsis Death 91 Female 8/20/2009 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 9/10/2009 Consumer United Kingdom
Primary
Concomitant
Urosepsis Death 91 Female 9/4/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 9/9/2009 Other Health Professional Denmark
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 9/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 55 Male 9/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death 78 Male 9/16/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 10/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 10/8/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/4/2008 85 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ankle Fracture Other Serious 9/8/2007 50 Male 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Depression Life Threatening 9/5/2005 59 Male 10/23/2009 United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 11/1/2007 61 Male 10/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 76 Male 10/23/2009 United Kingdom
Primary
Concomitant
Syncope Death 1/6/2009 79 Female 10/23/2009 United Kingdom
Primary
Concomitant

Drug Data