Acetylcysteine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Hospitalization 10/14/2004 46 Male 188 lb 1/12/2006 Physician Germany
Primary
Secondary
Concomitant
Coronary Artery Thrombosis Life Threatening 10/7/2004 68 Male 1/19/2006 Consumer Finland
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/22/2006 83 Female 4/26/2006 Sweden
Primary
Secondary
Concomitant
Death Death 3/29/2006 67 Female 6/14/2006 Other Health Professional Denmark
Primary
Concomitant
Death Death 3/29/2006 67 Female 6/28/2006 Other Health Professional Denmark
Primary
Concomitant
White Blood Cell Count Decreased Death 6/28/2006 58 Male 172 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 7/20/2006 Other Health Professional Sweden
Primary
Concomitant
Thrombocytopenia Other Serious 79 Male 196 lb 5/9/2005 Pharmacist United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/4/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/25/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 9/8/2006 Other Health Professional Sweden
Primary
Concomitant
Confusional State Hospitalization 10/9/2006 Male 154 lb 10/19/2006 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 6/22/2006 59 Male 172 lb 10/28/2006 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 65 Male 12/15/2006 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 11/27/2006 67 Male 196 lb 1/15/2007 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 3/8/2007 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 5/4/2007 Other Health Professional Sweden
Primary
Concomitant
Ventricular Tachycardia Death 6/6/2007 65 Male 187 lb 6/15/2007 Pharmacist Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/27/2007 Other Health Professional Sweden
Primary
Concomitant
Colon Neoplasm Hospitalization 8/3/2007 77 Male 8/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 5/31/2007 65 Male 9/27/2007 Other Health Professional Netherlands
Primary
Concomitant
Pneumonia Hospitalization 10/14/2004 46 Male 188 lb 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Epistaxis Hospitalization 9/5/2007 Female 11/29/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2007 Male 200 lb 12/19/2007 United States
Primary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Jaundice Other Serious 1/1/2008 70 Male 3/12/2008 Physician Germany
Primary
Concomitant
Seizure Anoxic Hospitalization 12/4/2007 87 Male 3/18/2008 Other Health Professional Sweden
Primary
Concomitant
Jaundice Hospitalization 2/1/2008 Male 3/21/2008 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/7/2008 Female 141 lb 4/25/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 4/7/2008 Female 141 lb 5/1/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 4/7/2008 Female 141 lb 5/21/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 4/7/2008 Female 141 lb 6/4/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/7/2008 Female 141 lb 6/18/2008 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 4/30/2008 81 Male 6/27/2008 Sweden
Primary
Concomitant
Sinus Tachycardia Other Serious 7/3/2008 Physician United Kingdom
Primary
Concomitant
Blood Pressure Decreased Hospitalization 12/20/2007 85 Female 7/10/2008 Physician Sweden
Primary
Concomitant
Suicide Attempt Other Serious 78 Male 134 lb 8/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/1/2008 Male 8/20/2008 Physician Sweden
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 10/20/2008 Female 176 lb 10/24/2008 Netherlands
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 9/8/2008 Female 176 lb 10/31/2008 Netherlands
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 9/8/2008 Female 176 lb 11/13/2008 Netherlands
Primary
Concomitant
Vascular Pseudoaneurysm Hospitalization 11/8/2008 82 Male 146 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Chest Discomfort Life Threatening 1/5/2009 2/9/2009 Other Health Professional Singapore
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 2/12/2009 Physician Netherlands
Primary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Shock Hypoglycaemic Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Germany
Primary
Secondary
Concomitant
Vomiting Other Serious Male 3/27/2009 Consumer Switzerland
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 4/7/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Tendon Rupture Hospitalization 1/22/2009 4/9/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Shock Hypoglycaemic Life Threatening 11/14/2008 83 Male 4/8/2009 Physician Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 150 lb 4/14/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Female 4/9/2009 Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 4/15/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 150 lb 5/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/17/2008 185 lb 6/15/2009 Physician Netherlands
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 10/14/2004 Male 188 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/17/2008 185 lb 6/25/2009 Physician Netherlands
Primary
Secondary
Concomitant
Urinary Retention Other Serious 10/14/2004 Male 7/2/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 4/6/2009 85 Male 326 lb 7/1/2009 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 4/25/2009 79 8/5/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Syncope Other Serious 4/15/2009 8/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 77 Female 8/24/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
No Therapeutic Response Hospitalization 8/13/2009 79 Male 9/14/2009 Physician
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/18/2008 181 lb 9/24/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Hospitalization 11/8/2008 82 Male 146 lb 9/24/2009 United States
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 5/9/2009 Male 10/21/2009 Physician Netherlands
Primary
Concomitant
Interacting
Alveolitis Other Serious 7/16/2009 75 Male 179 lb 11/20/2009 Consumer United States
Primary
Secondary
Concomitant
Oesophageal Ulcer Haemorrhage Hospitalization 5/9/2009 76 Male 11/23/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Respiratory Tract Infection Hospitalization 3/12/2009 75 Male 161 lb 11/13/2009 Physician United States
Primary
Concomitant
Oedema Mouth Hospitalization 8/13/2009 79 Male 11/25/2009 Physician Germany
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 11/1/2007 60 Male 227 lb 1/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Colour Abnormal Life Threatening 10/27/2009 61 Male 154 lb 1/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Alveolitis Other Serious 7/16/2009 75 Male 179 lb 1/14/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/1/2007 46 Male 198 lb 1/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Colour Abnormal Life Threatening 10/27/2009 61 Male 154 lb 1/19/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Urine Colour Abnormal Life Threatening 10/1/2009 61 Male 1/26/2010 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Death 10/27/2009 61 Male 1/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Urine Colour Abnormal Life Threatening 10/1/2009 61 Male 1/28/2010 Physician Germany
Primary
Secondary
Concomitant
Urine Colour Abnormal Life Threatening 10/27/2009 61 Male 154 lb 2/22/2010 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/4/2007 76 Female 2/25/2010 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Death 10/27/2009 61 Male 3/2/2010 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/30/2010 70 Male 3/12/2010 Physician Germany
Primary
Concomitant
Tachyarrhythmia Other Serious 11/25/2009 69 Male 194 lb 4/1/2010 Germany
Primary
Concomitant
Rhabdomyolysis Death 10/27/2009 61 Male 4/7/2010 Physician Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 77 Female 4/14/2010 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Urine Colour Abnormal Life Threatening 10/1/2009 61 Male 4/16/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Urine Colour Abnormal Life Threatening 10/27/2009 61 Male 154 lb 4/20/2010 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Death 10/27/2009 61 Male 4/29/2010 Physician Germany
Primary
Secondary
Concomitant
Urine Colour Abnormal Life Threatening 10/1/2009 61 Male 4/29/2010 Physician Germany
Primary
Secondary
Concomitant
Urine Colour Abnormal Life Threatening 10/1/2009 61 Male 5/11/2010 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/4/2007 76 Female 6/24/2010 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/26/2010 59 Male 163 lb 6/25/2010 Physician
Primary
Concomitant
Anaphylactic Reaction Hospitalization 4/29/2010 70 Male 207 lb 6/28/2010 Other Health Professional Sweden
Primary
Concomitant
Visual Field Defect Other Serious 1/1/2008 76 Male 7/12/2010 Physician
Primary
Concomitant
Tracheal Operation Hospitalization 1/1/2010 86 Male 7/12/2010 Consumer Brazil
Primary
Concomitant
Pyrexia Hospitalization 6/7/2010 64 Male 130 lb 7/12/2010 Consumer United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 54 Female 7/15/2010 Lawyer United States
Primary
Concomitant
Prothrombin Level Decreased Hospitalization 2/19/2010 86 Male 8/17/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Death Death 71 Male 198 lb 9/3/2010 Physician Germany
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2008 54 Female 84 lb 9/8/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 7/27/2010 73 Female 9/14/2010 Consumer France
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/2/2010 86 Male 132 lb 9/22/2010 Physician Germany
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 11/1/2007 60 Male 227 lb 9/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/7/2010 80 Female 183 lb 9/24/2010 Physician Canada
Primary
Secondary
Concomitant
Lung Infection Death Female 161 lb 10/6/2010 Consumer Brazil
Primary
Concomitant
Muscular Weakness Hospitalization 7/31/2010 64 Male 11/1/2010 Other Health Professional Sweden
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/13/2010 72 Female 11/8/2010 Physician Germany
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2008 54 Female 84 lb 11/19/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Death 11/21/2008 66 Female 143 lb 11/30/2010 Physician Netherlands
Primary
Concomitant
Ventricular Fibrillation Other Serious 8/4/2007 46 Male 198 lb 12/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 7/17/2010 68 Male 11/19/2010 Sweden
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/30/2010 65 Female 1/21/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 12/1/2010 62 Male 1/24/2011 Physician Germany
Primary
Secondary
Concomitant
Adverse Drug Reaction Hospitalization 12/30/2010 65 Female 1/27/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 79 Male 1/28/2011 Physician
Primary
Concomitant
Liver Disorder Other Serious 1/1/2008 54 Female 84 lb 2/8/2011 Lawyer United States
Primary
Concomitant
Anaphylactic Shock Hospitalization Female 2/21/2011 Consumer Italy
Primary
Concomitant
Pneumonia Death 12/30/2010 65 Female 2/25/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Palpitations Other Serious 6/14/2010 82 Male 163 lb 3/14/2011 Physician Germany
Primary
Concomitant
Alcohol Abuse Other Serious 7/1/2004 43 Male 282 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 6/14/2010 82 Male 163 lb 3/29/2011 Physician Germany
Primary
Concomitant
Respiratory Arrest Death 1/1/2010 86 Male 3/31/2011 Consumer Brazil
Primary
Concomitant
Duodenal Ulcer Hospitalization 4/26/2011 70 Male 168 lb 5/11/2011 Consumer United States
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 4/26/2011 70 Male 168 lb 5/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 4/26/2011 70 Male 168 lb 6/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Spasticity Hospitalization 4/3/2011 82 Female 6/15/2011 Other Health Professional Sweden
Primary
Concomitant
Pathological Fracture Hospitalization 4/25/2011 78 Female 6/16/2011 Other Health Professional Sweden
Primary
Concomitant
General Physical Health Deterioration Hospitalization 10/20/2010 Male 181 lb 6/22/2011 Physician Germany
Primary
Concomitant
Blood Amylase Increased Hospitalization 3/30/2011 57 Male 6/27/2011 Physician Sweden
Primary
Secondary
Concomitant
Haemorrhage Intracranial Other Serious 5/3/2011 78 Male 225 lb 6/28/2011 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 5/3/2011 78 Male 225 lb 6/29/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Pneumonia Death 12/17/2010 83 Male 172 lb 7/2/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea At Rest Death 10/20/2010 Male 181 lb 7/13/2011 Physician Germany
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/20/2010 Male 181 lb 9/11/2011 Physician Germany
Primary
Concomitant
Alveolitis Hospitalization 4/13/2011 68 Male 10/4/2011 Consumer Sweden
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/1991 60 Female 10/4/2011 Physician Germany
Primary
Secondary
Concomitant
Headache Hospitalization 5/1/2011 65 Male 10/6/2011 Physician Sweden
Primary
Concomitant

Drug Data