Propranolol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/3/2006 Physician Germany
Primary
Concomitant
Coronary Artery Surgery Other Serious 6/2/2005 74 Female 1/12/2006 Brazil
Primary
Concomitant
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/30/2006 Physician Germany
Primary
Concomitant
Sensory Disturbance 1/1/2004 61 Male 2/28/2006 Consumer United States
Primary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Myalgia Other Serious 43 Male 172 lb 4/12/2006 Consumer Brazil
Primary
Concomitant
Post Procedural Complication Death 2/1/2006 53 Male 5/1/2006 United States
Primary
Concomitant
Oedema Other Serious 3/13/2006 80 Male 162 lb 5/17/2006 Physician Canada
Primary
Concomitant
Lethargy Hospitalization 4/23/2006 77 Male 208 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Personality Change Hospitalization 6/3/2006 59 Male 217 lb 6/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 1/14/2006 Female 7/3/2006 Consumer United States
Primary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 7/14/2006 United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 12/12/2005 51 Female 2/27/2006 United States
Primary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 7/21/2006 Poland
Primary
Secondary
Concomitant
Diabetes Mellitus Life Threatening 11/18/2005 63 Male 198 lb 7/28/2006 Physician Germany
Primary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 8/16/2006 Poland
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2000 52 Female 143 lb 8/25/2006
Primary
Secondary
Concomitant
Neck Pain Other Serious 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Rhabdomyolysis Death Male 154 lb 9/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Type Iv Hypersensitivity Reaction Life Threatening 9/7/2006 Female 260 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 47 Female 10/12/2006 Consumer Brazil
Primary
Concomitant
Culture Urine Positive Hospitalization 9/16/2006 71 Female 10/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 47 Female 10/28/2006 Consumer Brazil
Primary
Concomitant
Diabetes Mellitus Life Threatening 11/18/2005 63 Male 198 lb 10/30/2006 Physician Germany
Primary
Concomitant
Tremor Other Serious 47 Female 11/10/2006 Physician Brazil
Primary
Concomitant
Tremor Other Serious 47 Female 11/15/2006 Physician Brazil
Primary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 84 Female 11/16/2006 Other Health Professional Brazil
Primary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 84 Female 11/21/2006 Other Health Professional Brazil
Primary
Concomitant
Tremor Other Serious 11/11/2006 50 Male 172 lb 12/20/2006 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 1/3/2007 Physician Austria
Primary
Concomitant
Respiratory Failure Other Serious Female 1/10/2007 Consumer Brazil
Primary
Concomitant
Ulcer Other Serious 7/5/2006 Female 119 lb 1/27/2007 Consumer Brazil
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/8/2006 54 Male 193 lb 12/20/2006 Pharmacist United States
Primary
Concomitant
Reflux Oesophagitis Other Serious 11/3/2003 85 Female 2/12/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 11/3/2003 85 Female 2/13/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 11/3/2003 85 Female 2/13/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Tremor Other Serious 47 Female 2/15/2007 Physician Brazil
Primary
Concomitant
Renal Failure Acute Hospitalization 4/13/2007 70 Female 5/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/13/2007 70 Female 5/16/2007 United Kingdom
Primary
Concomitant
Renal Failure Chronic Hospitalization 1/19/2007 Female 137 lb 5/23/2007 Brazil
Primary
Concomitant
Renal Failure Chronic Hospitalization 1/19/2007 Female 137 lb 5/24/2007 Brazil
Primary
Concomitant
Renal Failure Acute Hospitalization 4/13/2007 70 Female 5/22/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/13/2007 70 Female 5/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2007 Female 168 lb 6/27/2007 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2007 Female 168 lb 7/27/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 7/11/2007 Female 202 lb 7/30/2007 Consumer United States
Primary
Concomitant
Interacting
Podagra Other Serious 7/17/2007 46 Male 176 lb 8/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Podagra Other Serious 7/17/2007 46 Male 176 lb 8/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 6/12/2007 40 Male 9/10/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/11/2007 Female 202 lb 9/14/2007 Physician United States
Primary
Concomitant
Interacting
Speech Disorder Other Serious 12/1/2006 69 Female 198 lb 9/24/2007 Consumer United Kingdom
Primary
Concomitant
Pain Other Serious 9/1/2007 Female 142 lb 9/27/2007 Consumer United States
Primary
Secondary
Concomitant
Infarction Hospitalization 5/8/2007 34 Female 9/28/2007 Consumer Brazil
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/1/2006 69 Female 198 lb 10/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/1/2006 69 Female 198 lb 10/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Cardiac Death Other Serious 8/28/2007 56 Female 11/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/1/2006 69 Female 202 lb 12/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 10/23/2007 29 Female 237 lb 11/28/2007 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 10/23/2007 29 Female 237 lb 12/4/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 11/1/2007 72 Male 165 lb 12/28/2007 Physician United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 5/1/2007 34 Female 1/15/2008 Consumer Brazil
Primary
Concomitant
Renal Failure Chronic Hospitalization 1/19/2007 Female 137 lb 1/15/2008 Brazil
Primary
Concomitant
Hypersensitivity Hospitalization 4/8/2006 79 Female 259 lb 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/13/2007 70 Female 3/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Influenza Like Illness Other Serious 3/1/2007 Female 187 lb 4/17/2008 Denmark
Primary
Concomitant
Pharmaceutical Product Complaint 2/1/2008 72 Female 185 lb 4/15/2008 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 4/24/2008 Male 151 lb 6/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Cardiac Death Other Serious 8/28/2007 56 Female 7/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Personality Change Hospitalization 2/22/2003 54 Male 8/8/2008 Consumer Denmark
Primary
Secondary
Concomitant
Personality Change Hospitalization 2/22/2003 54 Male 8/13/2008 Consumer Denmark
Primary
Secondary
Concomitant
Scab Hospitalization 8/15/1997 Female 172 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Drug Interaction 4/14/2008 Male 6/26/2008 Pharmacist United States
Primary
Concomitant
Interacting
Renal Impairment Hospitalization 3/26/2008 Female 8/27/2008 Physician United Kingdom
Primary
Concomitant
Angle Closure Glaucoma Other Serious 8/10/2008 61 Female 79 lb 9/4/2008 Physician United Kingdom
Primary
Concomitant
Dyspepsia Hospitalization 3/8/2008 48 Male 215 lb 9/4/2008 Physician Brazil
Primary
Concomitant
Personality Change Hospitalization 2/22/2003 54 Male 9/4/2008 Consumer Denmark
Primary
Secondary
Concomitant
Accidental Exposure 7/18/2008 Male 175 lb 9/12/2008 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 10/2/2004 50 Male 9/10/2008 Denmark
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 3/18/2007 Male 9/22/2008 Consumer United States
Primary
Concomitant
Quadriparesis Hospitalization 7/10/2008 Female 10/2/2008 Other Health Professional France
Primary
Concomitant
Interacting
Rash Hospitalization 10/10/2007 53 Male 10/6/2008 Consumer Denmark
Primary
Secondary
Concomitant
Rash Hospitalization 10/10/2007 53 Male 10/13/2008 Consumer Denmark
Primary
Secondary
Concomitant
Influenza Like Illness Other Serious 59 Female 152 lb 10/17/2008 Other Health Professional Japan
Primary
Concomitant
Upper Limb Fracture Other Serious 3/18/2007 Male 11/24/2008 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 8/1/2008 Female 175 lb 12/17/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/1/2008 Female 173 lb 12/31/2008 Consumer Brazil
Primary
Concomitant
Somnolence Other Serious 12/15/2008 Male 143 lb 1/9/2009 Consumer Brazil
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2008 1/22/2009 Consumer Brazil
Primary
Concomitant
Somnolence Other Serious 12/15/2008 Male 143 lb 1/28/2009 Consumer Brazil
Primary
Concomitant
Rhinorrhoea 8/1/2008 Female 175 lb 2/3/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/15/2008 63 Male 172 lb 2/11/2009 Physician Germany
Primary
Secondary
Concomitant
Stress Other Serious 8/26/2008 Male 2/24/2009 Pharmacist South Africa
Primary
Concomitant
Visual Impairment Other Serious 4/15/2008 Female 2/25/2009 United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 4/15/2008 Female 128 lb 3/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 4/15/2008 Female 3/6/2009 United Kingdom
Primary
Concomitant
Wound Abscess Other Serious 12/1/2004 Male 234 lb 4/6/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 72 Male 161 lb 4/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 72 Male 161 lb 4/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Wound Abscess Other Serious 12/1/2004 Male 234 lb 5/1/2009 Physician United States
Primary
Secondary
Concomitant
Rash Female 6/23/2009 Consumer United States
Primary
Concomitant
Delirium Hospitalization 78 7/21/2009 Physician Netherlands
Primary
Concomitant
Hypotonic-hyporesponsive Episode Other Serious 5/17/2009 Female 8/3/2009 Pharmacist Italy
Primary
Secondary
Concomitant
Visual Impairment Disability 4/15/2008 Female 7/31/2009 United Kingdom
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 50 Female 7/31/2009 Physician Israel
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2009 Female 96 lb 8/11/2009 Physician Brazil
Primary
Secondary
Concomitant
Delirium Hospitalization 78 8/13/2009 Physician Netherlands
Primary
Concomitant
Migraine 8/1/2008 Female 8/21/2009 United States
Primary
Concomitant
Sensory Disturbance 1/1/1998 Male 8/22/2009 United States
Primary
Concomitant
Pruritus 6/8/2009 75 Female 170 lb 8/22/2009 United States
Primary
Concomitant
Convulsion Other Serious Male 9/2/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/18/2009 63 Female 131 lb 9/10/2009 Physician United Kingdom
Primary
Concomitant
Nodule Other Serious Female 176 lb 9/11/2009 Brazil
Primary
Concomitant
Incorrect Dose Administered 7/18/2008 Male 175 lb 9/12/2009 Consumer United States
Primary
Concomitant
Nausea Hospitalization 6/1/2009 Female 138 lb 9/17/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 9/14/2009 70 Female 9/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 3/30/2001 48 Male 265 lb 9/23/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2009 53 Female 104 lb 9/24/2009 Consumer Brazil
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/2/2009 83 Female 9/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 9/10/2009 Female 150 lb 9/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2008 53 Female 104 lb 10/2/2009 Consumer Brazil
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/2008 53 Female 104 lb 10/8/2009 Consumer Brazil
Primary
Secondary
Concomitant
Cholangitis Hospitalization 8/20/2009 Female 126 lb 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnambulism Other Serious 10/3/2009 53 Male 160 lb 10/7/2009 Pharmacist United States
Primary
Concomitant
Podagra 7/17/2007 46 Male 10/8/2009 United Kingdom
Primary
Concomitant
Angioedema Required Intervention 4/22/2009 67 Female 10/14/2009 Pharmacist United States
Primary
Concomitant
Nodule Other Serious Female 176 lb 10/27/2009 Brazil
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2009 Female 96 lb 11/2/2009 Physician Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 72 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 11/18/2009 United States
Primary
Concomitant
Visual Field Defect Hospitalization 66 Female 11/20/2009 United States
Primary
Concomitant
Surgery Other Serious 75 Female 11/24/2009 Lawyer United States
Primary
Concomitant
Pain In Jaw Other Serious 9/3/2009 36 Female 172 lb 12/8/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Female 12/1/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 4/15/2008 Female 12/8/2009 United Kingdom
Primary
Concomitant
Wound Secretion Hospitalization 66 Female 12/10/2009 United States
Primary
Concomitant
Weaning Failure Other Serious Male 164 lb 12/21/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 10/1/2007 76 Male 172 lb 12/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/9/2009 61 Male 12/23/2009 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/15/2008 Female 12/17/2009 Consumer United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 12/3/2009 62 Male 160 lb 12/24/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 9/1/2009 Female 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Administered At Inappropriate Site 1/7/2010 Female 1/18/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Female 1/12/2010 United States
Primary
Concomitant
Surgery Other Serious 75 Female 1/13/2010 Lawyer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2009 Female 220 lb 1/25/2010 Brazil
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Female 1/21/2010 United States
Primary
Concomitant
Pyrexia Other Serious 75 Female 1/22/2010 United States
Primary
Concomitant
Wound Abscess Other Serious 12/1/2004 Male 234 lb 2/11/2010 Physician United States
Primary
Secondary
Concomitant

Drug Data