Furosemide combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/3/2006 Physician Germany
Primary
Concomitant
Tachycardia Death 11/17/2005 77 Female 1/3/2006 Other Health Professional Netherlands
Primary
Concomitant
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
Renal Impairment Other Serious 7/25/2005 30 Female 1/3/2006 Brazil
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/14/2004 46 Male 188 lb 1/12/2006 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Death 11/19/2005 Male 1/13/2006 Italy
Primary
Secondary
Concomitant
Haemorrhagic Stroke Other Serious 10/13/2004 76 Female 1/17/2006 Physician Brazil
Primary
Concomitant
Angioneurotic Oedema Hospitalization 10/11/2005 80 Male 10/27/2005 Pharmacist United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 1/12/2006 Czech Republic
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 176 lb 1/12/2006 Netherlands
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Rhabdomyolysis Death 11/19/2005 Male 1/19/2006 Italy
Primary
Secondary
Concomitant
Septic Shock Other Serious 6/1/2005 55 Female 1/13/2006 Physician Sweden
Primary
Concomitant
Skin Oedema Other Serious 1/1/2005 79 Male 1/13/2006 United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Required Intervention 1/10/2006 84 Male 144 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Oedema Required Intervention 12/9/2005 82 Male 272 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Toe Amputation Hospitalization 10/1/2005 73 Male 1/12/2006 Physician Netherlands
Primary
Concomitant
Sepsis Death 12/1/2005 60 Male 187 lb 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 6/1/2005 55 Female 1/23/2006 Physician Sweden
Primary
Concomitant
Nephropathy Toxic Required Intervention 7/28/2005 66 Male 157 lb 10/25/2005 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 76 Male 1/10/2006 France
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 11/2/2005 Male 1/26/2006 Italy
Primary
Secondary
Concomitant
Urinary Tract Infection Disability 9/2/2005 81 Male 235 lb 1/26/2006 Pharmacist United States
Primary
Concomitant
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/30/2006 Physician Germany
Primary
Concomitant
Somnolence Hospitalization 6/28/2005 62 Male 141 lb 1/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious Female 1/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Arrhythmia Required Intervention 10/31/2005 58 Male 269 lb 10/31/2005 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/28/2005 Male 197 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haematoma Required Intervention 12/1/2005 81 Male 190 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Proteinuria Other Serious 7/7/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Proteinuria Other Serious 7/5/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Bradycardia Life Threatening 10/6/2005 59 Male 202 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/30/2005 Male 153 lb 1/3/2006 Other Health Professional United States
Primary
Concomitant
Venous Thrombosis Other Serious 11/11/2004 Male 225 lb 2/7/2006 Physician United States
Primary
Concomitant
Oedema Hospitalization 11/8/2005 62 292 lb 11/8/2005 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 10/3/2005 79 Male 193 lb 10/5/2005 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Overdose Other Serious 75 Male 2/3/2006 Physician France
Primary
Concomitant
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Tremor Hospitalization 12/14/2005 86 Male 2/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Subcutaneous Emphysema Other Serious 10/1/2003 Male 203 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/13/2005 68 Male Pharmacist United States
Primary
Concomitant
Skin Oedema Other Serious 1/1/2005 79 Male 2/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Dizziness Postural Hospitalization 10/12/2005 Male 144 lb 10/13/2005 Pharmacist United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/13/2005 Male 171 lb 11/18/2005 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/24/2006 61 Female 2/14/2006 United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 9/1/2004 Male 227 lb 2/15/2006 France
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 9/1/2004 Male 227 lb 2/15/2006 France
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/2005 Male 203 lb 2/16/2006 Consumer France
Primary
Concomitant
Palpable Purpura Hospitalization 1/25/2006 66 Male 161 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 5/15/2003 76 Female 77 lb 2/21/2006 Lawyer United Kingdom
Primary
Concomitant
Procedural Site Reaction Hospitalization 11/21/2005 Male 2/15/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/14/2006 69 Male 2/21/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 89 Male 2/21/2006 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 74 Male 2/13/2006 Canada
Primary
Secondary
Concomitant
Dysgeusia 12/3/2005 76 Female 130 lb 1/5/2006 Consumer United States
Primary
Concomitant
Coma Death 3/15/2004 77 Male 2/15/2006 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/28/2006 75 Female 2/13/2006 Japan
Primary
Concomitant
Hypoglycaemia Other Serious 11/3/2005 77 Male 174 lb 12/7/2005 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Flatulence 12/1/2005 65 Male 2/27/2006 Consumer United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 1/23/2006 74 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 2/24/2006 Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 12/19/2005 77 Female 115 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Incoherent Hospitalization 6/14/2005 65 Male 3/6/2006 Other Health Professional Spain
Primary
Concomitant
Interacting
Diabetes Mellitus Non-insulin-dependent Hospitalization 57 Male 225 lb 3/6/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Insomnia 10/19/2005 80 Male 3/7/2006 Consumer United States
Primary
Concomitant
Insomnia 10/19/2005 80 Male 3/7/2006 Consumer United States
Primary
Concomitant
Metabolic Encephalopathy Other Serious 1/1/2005 65 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 1/31/2006 81 Male 3/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 2/15/2006 59 Male 220 lb 3/7/2006 United Kingdom
Primary
Concomitant
Viral Infection Other Serious Male 168 lb 3/8/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 3/8/2006 Netherlands
Primary
Secondary
Concomitant
Catheter Site Haemorrhage Hospitalization 10/11/2004 65 Male 217 lb 12/21/2005 United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 8/29/2004 75 Female 170 lb 12/29/2005 Other Health Professional United States
Primary
Concomitant
Factor V Leiden Mutation Hospitalization 2/17/2006 85 Male 187 lb 3/14/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 11/1/2004 61 Female 12/21/2005 Consumer United States
Primary
Concomitant
Wound Other Serious 1/1/2005 78 Male 170 lb 3/2/2006 United States
Primary
Concomitant
Myalgia Other Serious 7/11/2005 68 Male 234 lb 2/8/2006 Pharmacist United States
Primary
Concomitant
Hypertension Other Serious 2/15/2006 59 Male 220 lb 3/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyperhidrosis Hospitalization 3/18/2006 67 Male 230 lb 3/22/2006 Pharmacist United States
Primary
Concomitant
Swollen Tongue Other Serious 2/12/2006 71 Male 3/9/2006 Consumer United Kingdom
Primary
Concomitant
Osteoporosis Hospitalization 1/1/2002 64 Female 220 lb 3/29/2006 Physician Germany
Primary
Concomitant
Somnolence Hospitalization 12/30/2004 80 Male 170 lb 3/30/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 3/28/2006 United States
Primary
Secondary
Concomitant
Retching 10/17/2005 Male 202 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 10/4/2005 70 Male 159 lb 3/31/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/4/2006 Female 126 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Pleurisy Hospitalization 3/12/2006 68 Male 187 lb 4/5/2006 United Kingdom
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 3/19/2006 71 Female 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Agitation Hospitalization 4/1/2006 Male 280 lb 4/14/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Hypertension Other Serious 3/1/2006 60 Female 4/7/2006 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 9/26/2005 71 Female 182 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Rhinorrhoea Other Serious 12/19/2005 67 Male 235 lb 4/14/2006 Pharmacist United States
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 4/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Required Intervention 4/18/2006 77 Male 134 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Humerus Fracture Hospitalization 4/4/2006 75 Female 199 lb 4/17/2006 Physician Germany
Primary
Concomitant
Hallucination Required Intervention 4/9/2006 79 Male 191 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 4/13/2006 76 Male 160 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Peritonitis Bacterial Hospitalization 11/29/2005 64 Male 209 lb 4/14/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 4/1/2006 Male 280 lb 4/26/2006 Physician United States
Primary
Concomitant
Sinus Bradycardia Life Threatening 1/25/2006 59 Male 250 lb 1/30/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2002 60 Female 4/28/2006 Other Health Professional Norway
Primary
Concomitant
Hypophosphataemia Life Threatening 8/31/2005 61 Female 5/1/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 2/14/2006 69 Female 4/12/2006 Physician United Kingdom
Primary
Concomitant
Tricuspid Valve Sclerosis Other Serious 1/1/2004 58 Male 4/25/2006 Denmark
Primary
Concomitant
Hypertension Other Serious 3/1/2006 60 Female 4/25/2006 Pharmacist Canada
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 1/2/2006 57 Male 132 lb 5/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Burning Sensation Hospitalization 11/1/2005 77 Female 134 lb 5/3/2006 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/22/2006 83 Female 4/26/2006 Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 74 Male 4/28/2006 Canada
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 2/26/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 2/27/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Death 4/15/2006 66 Male 214 lb 5/1/2006 Pharmacist United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 2/14/2006 69 Female 4/27/2006 Physician United Kingdom
Primary
Concomitant
Lymphoma Death 1/1/2005 86 Female 5/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 65 Female 5/10/2006
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 73 Male 5/5/2006 Physician United Kingdom
Primary
Secondary
Pleurisy Hospitalization 3/12/2006 68 Male 187 lb 5/5/2006 United Kingdom
Primary
Secondary
Concomitant
Myopathy Hospitalization 1/19/2006 79 Female 5/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 3/14/2006 49 Male 212 lb 5/8/2006 United States
Primary
Concomitant
Fall Hospitalization 2/21/2006 74 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Myopathy Hospitalization 1/19/2006 79 Female 5/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/20/2006 65 Male 5/8/2006 Other Health Professional United States
Primary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
Chest Pain Life Threatening 2/16/2006 84 Female 2/17/2006 Pharmacist United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 9/3/2005 46 Male 5/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/17/2006 70 Male 5/10/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 11/2/2005 Male 5/17/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 5/18/2006 Physician Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 2/23/2006 Male 5/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/16/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Death Female 138 lb 5/19/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 5/5/2006 64 Male 206 lb 5/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Hospitalization 5/15/2006 64 Male 284 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/30/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Convulsion Hospitalization 1/2/2006 Male 5/17/2006 Pharmacist United States
Primary
Secondary
Concomitant

Drug Data