Azathioprine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Fibrosis Death 8/25/2005 Female 1/20/2006 United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 8/25/2005 Female 148 lb 2/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious 2/11/2006 47 Male 2/23/2006 Brazil
Primary
Concomitant
Malaise Other Serious 2/11/2006 47 Male 2/23/2006 Brazil
Primary
Concomitant
Meningitis Bacterial Other Serious 2/11/2006 47 Male 3/31/2006 Other Health Professional Brazil
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/22/2006 30 Female 6/7/2006 Consumer Portugal
Primary
Concomitant
Rhabdomyolysis Other Serious 74 Female 6/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Hospitalization 7/14/2006 Male 242 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Soft Tissue Necrosis Other Serious 1/1/2006 Female 157 lb 9/6/2006 Physician Germany
Primary
Secondary
Concomitant
Paraesthesia Death 1/1/2006 Female 157 lb 9/7/2006 Physician Germany
Primary
Secondary
Concomitant
Soft Tissue Necrosis Other Serious 1/1/2006 Female 157 lb 9/29/2006 Physician Germany
Primary
Secondary
Concomitant
Soft Tissue Necrosis Other Serious 1/1/2006 Female 157 lb 10/11/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 Female 157 lb 10/18/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/18/2006 75 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Sinus Disorder Hospitalization 12/1/2002 57 Male 11/16/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 10/24/2006 Female 11/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 10/24/2006 Female 11/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 3/14/2005 Female 148 lb 12/15/2006 Consumer United Kingdom
Primary
Concomitant
Drug Level Increased Other Serious 12/1/2006 65 Male 1/19/2007 United Kingdom
Primary
Secondary
Concomitant
Lentigo Maligna Stage Unspecified Other Serious 2/16/2007 Male 191 lb 3/14/2007 Physician Australia
Primary
Concomitant
Rhabdomyolysis Hospitalization 69 Male 4/30/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 3/29/2007 60 Male 5/8/2007 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 7/31/2007 84 Male 9/1/2007 United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 5/1/2007 83 Male 11/2/2007 United Kingdom
Primary
Concomitant
Rash Other Serious 8/1/2007 74 Female 11/21/2007
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 52 Female 12/18/2007 Turkey
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 64 Male 259 lb 1/22/2008 Physician United States
Primary
Secondary
Concomitant
Lentigo Maligna Stage Unspecified Other Serious 2/16/2007 Male 191 lb 1/30/2008 Physician Australia
Primary
Concomitant
Rash Erythematous Other Serious 10/4/2007 Male 2/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 7/6/2007 Male 2/5/2008 Physician United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 12/17/2007 75 Male 2/11/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 52 Female 2/22/2008 Physician Turkey
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 7/6/2007 Male 2/28/2008 Physician United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious 10/4/2007 Male 2/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rash 1/11/2008 Female 213 lb 3/15/2008 Consumer United States
Primary
Concomitant
Reticulocyte Count Increased Hospitalization 33 Male 3/26/2008 United States
Primary
Secondary
Concomitant
Skin Lesion Required Intervention 1/2/2008 71 Female 209 lb 3/19/2008 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased 2/14/2008 Male 4/9/2008 Consumer United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 4/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Lentigo Maligna Stage Unspecified Other Serious 2/16/2007 Male 191 lb 4/21/2008 Physician Australia
Primary
Concomitant
Blood Glucose Increased 2/14/2008 Male 5/2/2008 Consumer United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 2/23/2008 65 Male 220 lb 5/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Hospitalization 1/1/2008 Female 245 lb 5/22/2008 Physician United Kingdom
Primary
Concomitant
Sleep Disorder Disability 1/1/2004 67 168 lb 5/29/2008 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/16/2008 55 Female 6/9/2008 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/16/2008 Female 6/17/2008 Other Health Professional Finland
Primary
Secondary
Concomitant
Polymyositis Disability 60 Female 6/9/2008 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/15/2006 63 Male 211 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Myopathy Other Serious 62 Male 7/24/2008 Switzerland
Primary
Concomitant
Interacting
White Blood Cell Count Increased Other Serious 8/15/2006 63 Male 211 lb 7/30/2008 Physician United States
Primary
Secondary
Concomitant
Rhodococcus Infection Hospitalization 8/12/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 8/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular 6/4/2008 69 Male 228 lb 8/4/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 69 Male 8/11/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 41 NotSpecified 8/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/9/2008 41 8/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Flushing 10/1/2007 Female 182 lb 8/27/2008 Consumer United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious Male 8/26/2008 United Kingdom
Primary
Concomitant
Rash Papular 2/1/2008 Female 137 lb 9/12/2008 United States
Primary
Concomitant
Cellulitis 6/6/2008 Male 165 lb 9/12/2008 United States
Primary
Concomitant
Subcutaneous Emphysema Other Serious 62 Male 11/19/2008
Primary
Secondary
Concomitant
Cellulitis 6/6/2008 Male 165 lb 12/12/2008 United States
Primary
Concomitant
Accidental Exposure 9/10/2008 Female 102 lb 12/12/2008 United States
Primary
Concomitant
Postoperative Adhesion Death 1/1/2008 Female 100 lb 12/24/2008 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 58 Female 12/26/2008 Canada
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/19/2008 55 Female 1/7/2009 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/13/2008 55 Female 1/7/2009 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/13/2008 Female 1/16/2009 Physician Finland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/19/2008 55 Female 1/16/2009 Consumer United Kingdom
Primary
Concomitant
Ubiquinone Decreased Hospitalization 61 Female 2/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ubiquinone Decreased Hospitalization 61 Female 2/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 64 Male 259 lb 2/5/2009 Physician United States
Primary
Secondary
Concomitant
Ubiquinone Decreased Hospitalization 61 Female 2/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/1/2008 Female 100 lb 3/6/2009 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 1/21/2009 73 Male 232 lb 3/4/2009 Physician United States
Primary
Concomitant
Lung Disorder Other Serious 1/16/2009 Female 3/11/2009 Physician United Kingdom
Primary
Concomitant
Ubiquinone Decreased Hospitalization 61 Female 3/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/6/2008 3/24/2009 Physician Germany
Primary
Concomitant
Interacting
Pyrexia Death 55 Female 4/1/2009 Physician Finland
Primary
Concomitant
Lung Disorder Other Serious 1/16/2009 Female 4/8/2009 Physician United Kingdom
Primary
Concomitant
Pyrexia Death 55 Female 4/17/2009 Consumer Finland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/16/2008 Female 4/17/2009 Consumer Finland
Primary
Secondary
Concomitant
Vomiting Hospitalization 71 Male 196 lb 4/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Death 55 Female 5/12/2009 Consumer Finland
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/6/2008 72 5/18/2009 Physician Germany
Primary
Concomitant
Interacting
Ubiquinone Decreased Hospitalization 61 Female 6/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 61 Female 6/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 47 Male 7/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 4/28/2009 Male 7/24/2009 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 55 Female 8/26/2009 Other Health Professional Finland
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Disability 1/4/2009 63 Male 154 lb 9/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Incorrect Dose Administered 9/10/2008 Female 102 lb 9/12/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 5/8/2009 Male 234 lb 9/18/2009 Other Health Professional Italy
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Renal Disorder Other Serious Female 140 lb 10/2/2009 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 10/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2001 52 Female 10/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 50 Female 10/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2001 52 Female 10/5/2009 Physician United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 10/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2001 52 Female 10/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 10/12/2009
Primary
Concomitant
Pyrexia Hospitalization 5/8/2009 Male 234 lb 10/24/2009 Italy
Primary
Concomitant
Sleep Disorder Disability 1/1/2004 67 Unknown 10/23/2009 United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 10/27/2009 United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2001 52 Female 10/27/2009 United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2005 50 Female 11/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2001 52 Female 11/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/18/2006 75 Female 11/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Cerebrovascular Accident Other Serious 1/1/2001 52 Female 11/3/2009 Physician United Kingdom
Primary
Concomitant
Pubis Fracture Disability 5/1/2007 72 Female 11/13/2009 Physician Singapore
Primary
Concomitant
Type Iv Hypersensitivity Reaction Other Serious 30 Female 11/11/2009 Portugal
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/27/2009 67 Male 214 lb 12/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2007 54 Female 12/4/2009 Consumer Brazil
Primary
Concomitant
Renal Failure Hospitalization 61 Female 12/11/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Cancer Hospitalization 10/1/2009 Male 200 lb 12/18/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 10/18/2009 Female 110 lb 10/19/2009 United States
Primary
Concomitant
Ear Discomfort Disability 12/6/2009 76 Male 12/22/2009 Physician United Kingdom
Primary
Concomitant
Oesophageal Hypomotility Other Serious 1/1/2004 Female 125 lb 1/11/2010 Consumer United States
Primary
Concomitant
Dysphagia Hospitalization 1/1/2010 Female 222 lb 1/26/2010 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2001 48 Female 2/1/2010 Consumer Brazil
Primary
Concomitant
Type Iv Hypersensitivity Reaction Hospitalization 30 Female 2/2/2010 Consumer Portugal
Primary
Concomitant
Skin Lesion Hospitalization 30 Female 2/12/2010 Other Health Professional Portugal
Primary
Concomitant
Interacting
Systemic Lupus Erythematosus Hospitalization 30 Female 2/15/2010 Portugal
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 30 Female 2/18/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 8/17/2009 2/18/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Ear Discomfort Disability 12/6/2009 76 Male 2/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 30 Female 2/19/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2001 56 Male 2/23/2010 Germany
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 8/15/2009 Female 214 lb 2/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pancytopenia Hospitalization 8/17/2009 56 Male 2/15/2010 Germany
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 8/5/2009 45 Female 3/10/2010 Other Health Professional Italy
Primary
Concomitant
Interacting
Paraesthesia Other Serious 26 Male 3/4/2010 Other Health Professional Canada
Primary
Concomitant
Pancytopenia Hospitalization 8/1/2009 3/17/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Other Serious 1/8/2010 66 Female 116 lb 1/10/2010 Pharmacist United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2001 56 Male 4/22/2010 Consumer Germany
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 59 Male 194 lb 4/22/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 29 Female 143 lb 6/4/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 5/1/2010 51 Female 6/1/2010 Brazil
Primary
Concomitant
Vision Blurred Other Serious 4/8/2010 65 Female 147 lb 7/23/2010 Other Health Professional Canada
Primary
Concomitant
Hyperkeratosis Other Serious Male 182 lb 7/29/2010 Consumer United Kingdom
Primary
Concomitant
Pulmonary Mass Hospitalization 6/3/2010 55 Female 8/3/2010 Physician Thailand
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/29/2010 55 Female 8/17/2010 Physician Thailand
Primary
Secondary
Concomitant
Oesophageal Perforation Hospitalization 75 Female 8/5/2010 Germany
Primary
Secondary
Concomitant
Viral Infection Hospitalization 8/8/2010 Female 8/20/2010 Physician Israel
Primary
Secondary
Concomitant
Actinic Keratosis Other Serious Male 190 lb 8/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Cellulitis Hospitalization 8/7/2010 69 Female 9/7/2010 Other Health Professional Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 45 Female 9/20/2010 Other Health Professional Italy
Primary
Secondary
Concomitant

Drug Data