Amlodipine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/3/2006 Physician Germany
Primary
Concomitant
Fatigue Other Serious 11/1/2005 75 Female 1/4/2006 Consumer United Kingdom
Primary
Concomitant
Sudden Death Hospitalization 11/11/2002 73 Female 106 lb 1/10/2006 Physician Israel
Primary
Concomitant
Weight Increased Hospitalization 10/14/2004 46 Male 188 lb 1/12/2006 Physician Germany
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 56 Male 1/20/2006 United Kingdom
Primary
Secondary
Concomitant
Interacting
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased 66 Male 1/30/2006 Physician United States
Primary
Concomitant
Brain Oedema Life Threatening 11/18/2005 63 Male 198 lb 1/30/2006 Physician Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 84 Male Pharmacist United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 7/7/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Proteinuria Other Serious 7/5/2005 50 Female 1/30/2006 Brazil
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 74 Male 249 lb 2/7/2006 Physician United Kingdom
Primary
Concomitant
Dry Throat 8/1/2005 80 Male 150 lb 1/5/2006 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 56 Male 2/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Lymphadenopathy Other Serious 11/1/2004 68 Female 194 lb 2/9/2006 Physician Germany
Primary
Secondary
Concomitant
Gastroenteritis Other Serious 5/24/2005 Female 115 lb 2/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Insomnia 10/5/2005 62 Female 210 lb 1/5/2006 Consumer United States
Primary
Concomitant
Nitritoid Crisis Life Threatening 10/18/2004 74 Male 2/20/2006 United Kingdom
Primary
Concomitant
Interacting
Mouth Ulceration Other Serious 12/10/2005 76 Male 2/22/2006 Consumer United Kingdom
Primary
Concomitant
Abnormal Dreams 1/1/2005 Female 1/5/2006 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 56 Male 2/27/2006 United Kingdom
Primary
Secondary
Concomitant
Interacting
Supraventricular Tachycardia Other Serious 56 Male 2/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hyperkalaemia Hospitalization 1/23/2006 74 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 56 Male 2/22/2006 United Kingdom
Primary
Secondary
Concomitant
Incoherent Hospitalization 6/14/2005 65 Male 3/6/2006 Other Health Professional Spain
Primary
Concomitant
Interacting
Metabolic Encephalopathy Other Serious 1/1/2005 65 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 1/31/2006 81 Male 3/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/22/2005 38 Male 245 lb 4/1/2005 Pharmacist United States
Primary
Concomitant
Dystonia 2/20/2006 54 Male 3/14/2006 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Female 130 lb 3/24/2006 Physician Canada
Primary
Concomitant
Interacting
Visual Disturbance Other Serious 6/1/2005 58 Male 231 lb 3/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 56 Male 3/21/2006 United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 2/25/2006 62 Male 256 lb 3/30/2006 Physician Australia
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 3/31/2006 Other Health Professional France
Primary
Concomitant
Vomiting Other Serious 2/28/1997 72 Female 4/1/2006 Australia
Primary
Concomitant
Diarrhoea Disability 1/12/2006 79 Female 143 lb 3/28/2006 Physician Portugal
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 223 lb 4/5/2006 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Female 130 lb 4/12/2006 Physician Canada
Primary
Concomitant
Interacting
Spondylitic Myelopathy Other Serious 1/1/2003 68 Female 100 lb 4/5/2006 Physician Japan
Primary
Secondary
Concomitant
Humerus Fracture Hospitalization 4/4/2006 75 Female 199 lb 4/17/2006 Physician Germany
Primary
Concomitant
Fall Hospitalization 74 Male 249 lb 4/24/2006 Physician United Kingdom
Primary
Concomitant
Skin Burning Sensation Hospitalization 11/1/2005 77 Female 134 lb 5/3/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 223 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
Hallucinations, Mixed Other Serious 3/23/2006 65 Male 5/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 55 Male 5/26/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 9/26/2005 60 Male 5/24/2006 Brazil
Primary
Secondary
Concomitant
Pollakiuria 4/12/2005 80 Male 175 lb 4/3/2006 Consumer United States
Primary
Concomitant
Somnolence Other Serious 55 Male 6/1/2006 Consumer United Kingdom
Primary
Concomitant
Nightmare 65 Female 200 lb 4/3/2006 Consumer United States
Primary
Concomitant
Insomnia 1/1/2006 75 Female 250 lb 4/3/2006 Consumer United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 6/2/2006 Consumer United Kingdom
Primary
Concomitant
Insomnia 2/1/2006 71 Male 160 lb 4/3/2006 Consumer United States
Primary
Concomitant
Hypoglycaemia Life Threatening 5/1/2006 68 Male 6/5/2006 Physician Netherlands
Primary
Concomitant
Somnolence Other Serious 55 Male 6/9/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 2/14/2006 Male 157 lb 6/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 3/19/2006 76 Male 5/28/2006 Other Health Professional Australia
Primary
Concomitant
Urinary Retention Hospitalization 11/19/2005 78 Male 196 lb 6/13/2006 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/19/2006 76 Male 6/7/2006 Other Health Professional Australia
Primary
Concomitant
Pyrexia Hospitalization 3/19/2006 76 Male 6/5/2006 Other Health Professional Australia
Primary
Concomitant
Somnolence Other Serious 55 Male 6/21/2006 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 4/24/2006 44 Male 6/5/2006 Pharmacist United Kingdom
Primary
Concomitant
Cerebrovascular Accident Death Male 157 lb 6/21/2006 Consumer United Kingdom
Primary
Concomitant
Skin Burning Sensation Hospitalization 11/1/2005 77 Female 134 lb 6/22/2006 Physician United Kingdom
Primary
Concomitant
Immobile Hospitalization 4/4/2006 75 Female 199 lb 6/30/2006 Other Health Professional United States
Primary
Concomitant
Angioneurotic Oedema Life Threatening 6/9/2006 72 Female 144 lb 6/14/2006 Other Health Professional United States
Primary
Concomitant
Impingement Syndrome Hospitalization 4/4/2006 80 Female 199 lb 7/10/2006 Physician Germany
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/17/2006 Other Health Professional Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/1/2002 66 Male 7/13/2006 United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 6/3/2006 75 Female 132 lb 7/18/2006 Physician Netherlands
Primary
Concomitant
Syncope Other Serious 6/8/2006 63 Male 189 lb 6/26/2006 Pharmacist United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/26/2006 Other Health Professional Japan
Primary
Concomitant
Syncope Other Serious 1/1/2006 Male 231 lb 7/21/2006 Physician Germany
Primary
Concomitant
Diabetes Mellitus Life Threatening 11/18/2005 63 Male 198 lb 7/28/2006 Physician Germany
Primary
Concomitant
Insomnia 6/9/2006 82 Female 106 lb 7/12/2006 Consumer United States
Primary
Concomitant
Hypertension Other Serious 1/1/2000 73 Male 217 lb 7/19/2006 Consumer United Kingdom
Primary
Concomitant
Palpitations Other Serious 10/24/2005 55 Female 220 lb 8/7/2006 Other Health Professional Netherlands
Primary
Concomitant
Insomnia 5/3/2005 50 Male 220 lb 7/12/2006 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 56 Male 8/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Coronary Artery Disease Hospitalization 9/9/2001 71 Male 176 lb 8/15/2006 France
Primary
Concomitant
Renal Failure Acute Other Serious 2/17/2006 75 Male 8/8/2006 Denmark
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/22/2005 Male 8/17/2006 Consumer France
Primary
Concomitant
Interacting
Metastasis Other Serious 6/20/2006 75 Female 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Off Label Use Other Serious 4/17/2006 79 Female 8/14/2006 United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2006 Male 231 lb 8/18/2006 Physician Germany
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 56 Male 8/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Supraventricular Tachycardia Other Serious 56 Male 8/24/2006 United Kingdom
Primary
Secondary
Concomitant
Interacting
Myositis Other Serious 56 Male 8/22/2006 United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 7/5/2004 56 Male 172 lb 8/26/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 9/16/2005 76 Male 134 lb 8/31/2006 United Kingdom
Primary
Concomitant
Pneumonia Aspiration Death 52 Female 9/13/2006 Physician United States
Primary
Secondary
Knee Arthroplasty Hospitalization 8/24/2006 76 Female 9/1/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/15/2006 69 Male 130 lb 9/11/2006 United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 5/9/2006 68 Male 9/13/2006 United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 6/1/2005 58 Male 231 lb 9/20/2006 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 56 Male 9/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Oedema Hospitalization 76 Male 9/21/2006 Physician United Kingdom
Primary
Concomitant
Circulatory Collapse Death 69 Male 9/30/2006 Physician Singapore
Primary
Secondary
Rhabdomyolysis Hospitalization 69 Male 10/3/2006 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 6/18/2006 87 Male 179 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 47 Female 10/12/2006 Consumer Brazil
Primary
Concomitant
Vomiting Hospitalization 7/25/2002 80 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Panic Attack 7/28/2006 71 Female 164 lb 10/9/2006 United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 7/1/2006 71 Female 10/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Limb Fracture Required Intervention 9/13/2006 62 Female 214 lb 9/28/2006 Physician Germany
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 7/4/2006 80 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 10/9/2006 Male 154 lb 10/19/2006 Physician Germany
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 7/1/2006 71 Female 201 lb 10/14/2006 United Kingdom
Primary
Secondary
Concomitant
Rales Other Serious 5/27/2003 66 Male 10/17/2006 United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 7/1/2006 71 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Other Serious 91 Male 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 73 Male 1766 lb 10/18/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/27/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Rash Disability 7/6/2006 Male 282 lb 10/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 47 Female 10/28/2006 Consumer Brazil
Primary
Concomitant
Diabetes Mellitus Life Threatening 11/18/2005 63 Male 198 lb 10/30/2006 Physician Germany
Primary
Concomitant
Onycholysis Other Serious Male 176 lb 10/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myositis Life Threatening 7/30/2006 79 Female 110 lb 10/25/2006 United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious 8/27/2006 66 Male 219 lb 9/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 7/1/2006 57 Male 172 lb 8/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Linear Iga Disease Other Serious 73 Male 10/26/2006 Physician United States
Primary
Concomitant
Malaise Hospitalization 1/10/2006 63 Female 192 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypercholesterolaemia Death Male 157 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Blood Creatine Increased Other Serious 57 Male 185 lb 10/30/2006 United Kingdom
Primary
Concomitant
Somnolence Hospitalization 1/1/2000 65 Male 10/31/2006 India
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 68 Female 11/8/2006 Other Health Professional Lebanon
Primary
Secondary
Concomitant
Ulcer Other Serious 63 Female 11/2/2006 Pharmacist United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death Female 126 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 47 Female 11/10/2006 Physician Brazil
Primary
Concomitant
Myocardial Ischaemia Death 69 Male 11/14/2006 Physician Singapore
Primary
Concomitant
Tremor Other Serious 47 Female 11/15/2006 Physician Brazil
Primary
Concomitant
Convulsion Other Serious 7/9/2006 72 Female 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Required Intervention 9/13/2006 62 Female 214 lb 10/31/2006 Physician Germany
Primary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 84 Female 11/16/2006 Other Health Professional Brazil
Primary
Concomitant
Rash Erythematous Other Serious 7/6/2006 Male 282 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 9/8/2006 61 Male 11/17/2006 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 62 Male 11/17/2006 Consumer United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 71 Male 185 lb 11/20/2006 Physician United Kingdom
Primary
Concomitant
Skin Lesion Other Serious 7/23/2006 72 Female 11/10/2006 United Kingdom
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 84 Female 11/21/2006 Other Health Professional Brazil
Primary
Concomitant
Transaminases Increased Hospitalization 9/8/2006 61 Male 11/22/2006 Physician Germany
Primary
Concomitant
Vision Blurred Hospitalization 10/26/2006 47 Male 110 lb 11/27/2006 Physician United Kingdom
Primary
Concomitant
Gout Disability 3/1/2006 86 Female 120 lb 12/5/2006 United Kingdom
Primary
Concomitant
Raynaud's Phenomenon Other Serious 57 Male 176 lb 12/7/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 10/26/2006 47 Male 110 lb 11/28/2006 United Kingdom
Primary
Concomitant
Syncope Life Threatening 9/30/2006 58 Male 12/7/2006 Physician Sweden
Primary
Concomitant
Dysphonia Other Serious 73 Female 12/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hidradenitis Hospitalization 68 Female 12/15/2006 Other Health Professional Lebanon
Primary
Concomitant

Drug Data