Allopurinol combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Hospitalization 9/1/2005 65 Female 1/12/2006 Switzerland
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/1/2005 65 Female 1/20/2006 Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 76 Male 1/10/2006 France
Primary
Secondary
Concomitant
Skin Lesion Other Serious 66 Male 180 lb 1/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Arrhythmia Supraventricular Hospitalization 12/12/2005 67 Male 1/30/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Gynaecomastia Other Serious 72 Male 1/24/2006 Spain
Primary
Secondary
Concomitant
Hypersensitivity Required Intervention 11/14/2005 79 Male 208 lb 11/16/2005 Pharmacist United States
Primary
Concomitant
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Rhabdomyolysis Hospitalization 84 Male Pharmacist United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 11/30/2005 Male 153 lb 1/3/2006 Other Health Professional United States
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 198 lb 2/8/2006
Primary
Concomitant
Lactic Acidosis Required Intervention 11/14/2005 57 Male 286 lb 1/24/2006 Pharmacist United States
Primary
Concomitant
Pancytopenia Death 74 Male 100 lb 1/25/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/24/2005 58 Male 203 lb 12/1/2005 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 9/1/2005 65 Female 2/7/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 9/1/2005 65 Female 2/7/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/2005 Male 203 lb 2/16/2006 Consumer France
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Pancytopenia Death 12/23/2005 74 Male 102 lb 2/6/2006 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 74 Male 2/13/2006 Canada
Primary
Secondary
Concomitant
Flatulence 12/1/2005 65 Male 2/27/2006 Consumer United States
Primary
Secondary
Concomitant
Arrhythmia Supraventricular Hospitalization 12/12/2005 67 Male 3/14/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/1/2005 65 Female 3/14/2006 Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Female 130 lb 3/24/2006 Physician Canada
Primary
Concomitant
Interacting
Hyperhidrosis Hospitalization 3/18/2006 67 Male 230 lb 3/22/2006 Pharmacist United States
Primary
Concomitant
Osteoporosis Hospitalization 1/1/2002 64 Female 220 lb 3/29/2006 Physician Germany
Primary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Hyponatraemia Hospitalization 1/22/2006 73 Male 3/29/2006 Spain
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Female 130 lb 4/12/2006 Physician Canada
Primary
Concomitant
Interacting
Respiratory Failure Other Serious 7/26/2005 67 Male 161 lb 2/14/2006 Physician Italy
Primary
Concomitant
Melaena Hospitalization 2/10/2006 89 Female 4/20/2006 Physician
Primary
Secondary
Concomitant
Humerus Fracture Hospitalization 4/4/2006 75 Female 199 lb 4/17/2006 Physician Germany
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/22/2006 83 Female 4/26/2006 Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 74 Male 4/28/2006 Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/1/2005 65 Female 5/1/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Tremor Hospitalization 2/7/2006 65 Male 157 lb 5/2/2006 Pharmacist United States
Primary
Concomitant
Post Procedural Complication Hospitalization 3/29/2006 66 Male 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 65 Female 5/10/2006
Primary
Secondary
Concomitant
Pleurisy Hospitalization 3/12/2006 68 Male 187 lb 5/5/2006 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 5/19/2005 65 Female 176 lb 5/11/2006
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/29/2006 66 Male 5/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 3/17/2006 79 Male 423 lb 5/16/2006 Pharmacist United States
Primary
Concomitant
Pleurisy Hospitalization 3/12/2006 68 Male 187 lb 5/17/2006 United Kingdom
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 4/21/2006 63 Male 176 lb 5/19/2006 Physician Germany
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 1/27/2006 53 Male 218 lb 2/23/2006 Pharmacist United States
Primary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Skin Reaction Other Serious 3/1/2006 79 Male 6/7/2006 Physician Netherlands
Primary
Concomitant
Renal Failure Hospitalization 10/14/2005 65 Male 5/30/2006 China
Primary
Concomitant
Dizziness Hospitalization 3/4/2006 83 Male 185 lb 6/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 4/1/2006 81 Male 6/8/2006 Other Health Professional France
Primary
Secondary
Cystitis Noninfective Hospitalization 7/29/2005 82 Male 190 lb 6/9/2006 Other Health Professional Germany
Primary
Concomitant
Sleep Disorder Hospitalization 4/21/2006 63 Male 176 lb 6/1/2006 Physician Germany
Primary
Concomitant
Skin Necrosis Hospitalization 4/24/2006 72 Male 198 lb 6/14/2006
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 3/30/2006 85 Male 5/23/2006 Belgium
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 4/20/2006 72 Male 6/15/2006 Other Health Professional France
Primary
Secondary
Drug Effect Decreased 63 Male 4/25/2006 United States
Primary
Concomitant
Hemiparesis Hospitalization 5/30/2006 73 Male 6/13/2006 Physician France
Primary
Concomitant
Cardiac Failure Other Serious 9/1/2005 75 Male 190 lb 5/3/2006 Physician Germany
Primary
Concomitant
Agranulocytosis Other Serious 2/14/2006 67 Female 148 lb 6/27/2006 Other Health Professional Germany
Primary
Concomitant
Skin Necrosis Hospitalization 4/20/2006 72 Male 198 lb 6/29/2006 Consumer France
Primary
Secondary
Concomitant
Muscle Spasms 3/31/2006 Male 212 lb 6/29/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/9/2006 56 Male 205 lb 6/23/2006 Physician Brazil
Primary
Concomitant
Arrhythmia Supraventricular Hospitalization 12/12/2005 67 Male 7/5/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/13/2006 67 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 6/23/2006 57 Male 192 lb 7/4/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Death Male 6/29/2006 Physician Germany
Primary
Concomitant
Immobile Hospitalization 4/4/2006 75 Female 199 lb 6/30/2006 Other Health Professional United States
Primary
Concomitant
Lethargy Hospitalization 5/5/2006 70 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/9/2006 56 Male 205 lb 7/5/2006 Physician Brazil
Primary
Concomitant
Impingement Syndrome Hospitalization 4/4/2006 80 Female 199 lb 7/10/2006 Physician Germany
Primary
Concomitant
Hypoglycaemia Hospitalization 4/14/2006 76 Male 7/11/2006 Sweden
Primary
Secondary
Concomitant
Syncope Other Serious 11/24/2005 64 Male 159 lb 7/5/2006 Physician Poland
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/1/2002 66 Male 7/13/2006 United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/19/2006 81 Male 110 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Streptococcal Infection Hospitalization 4/24/2006 72 Male 198 lb 7/20/2006
Primary
Secondary
Concomitant
Rash Hospitalization 5/29/2006 81 Male 243 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 1/1/2005 77 Male 7/14/2006 Consumer Canada
Primary
Concomitant
Skin Necrosis Hospitalization 4/20/2006 72 Male 7/24/2006 Other Health Professional France
Primary
Secondary
Hyperhidrosis Required Intervention 7/11/2006 54 Male 165 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Muscular Weakness Hospitalization 5/5/2006 Male 7/19/2006 Pharmacist United States
Primary
Concomitant
Sepsis Required Intervention 8/13/2005 58 Male 194 lb 7/8/2006 Pharmacist United States
Primary
Concomitant
Bradycardia Hospitalization 6/5/2006 71 Male Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/15/2006 88 Male 198 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Troponin I Increased Hospitalization 69 Male 7/20/2006 United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 52 Male 209 lb 7/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Erectile Dysfunction 3/6/2006 78 Male 6/28/2006 United States
Primary
Concomitant
Treatment Noncompliance Death 3/28/2005 68 Male 163 lb 7/25/2006 Pharmacist United States
Primary
Concomitant
Streptococcal Infection Hospitalization 4/20/2006 72 Male 198 lb 7/28/2006 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/1/2006 Male 119 lb 7/28/2006 Other Health Professional France
Primary
Secondary
Cardiac Failure Other Serious 9/1/2005 75 Male 190 lb 7/14/2006 Physician Germany
Primary
Concomitant
Sudden Death Death 3/4/2006 43 Male 7/25/2006 Physician Germany
Primary
Concomitant
Hypertension Other Serious 1/1/2000 73 Male 217 lb 7/19/2006 Consumer United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 7/19/2006 77 Male 8/3/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 67 Female 7/28/2006 Pharmacist Germany
Primary
Concomitant
Myalgia Other Serious 5/15/2006 88 Female 7/28/2006 United Kingdom
Primary
Concomitant
Constipation Required Intervention 8/1/2006 80 Male 175 lb 8/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Nausea 4/25/2006 69 Female 200 lb 7/12/2006 Consumer United States
Primary
Concomitant
Urinary Hesitation Hospitalization 7/29/2006 72 Male 219 lb 8/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5/7/2005 71 Female 209 lb 8/10/2006 Physician United States
Primary
Concomitant
Vomiting Death 6/7/2006 69 Male 8/4/2006 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2006 81 Male 8/8/2006 France
Primary
Secondary
Respiratory Failure Hospitalization 5/22/2006 60 Male 8/10/2006 Netherlands
Primary
Concomitant
Sepsis Hospitalization 7/20/2006 56 Male 203 lb 8/10/2006 Physician Brazil
Primary
Concomitant
Myalgia 5/2/2006 Male 229 lb 8/16/2006 Pharmacist United States
Primary
Concomitant
Vomiting Death 6/7/2006 69 Male 8/14/2006 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 6/19/2006 77 Male 8/23/2006 Other Health Professional France
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/23/2006
Primary
Concomitant
Transplant Rejection Hospitalization 4/17/2006 55 Male 261 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 8/3/2006 76 Male 8/25/2006 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haemorrhage Other Serious 9/17/2004 74 Female 141 lb 8/28/2006 Australia
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/22/2006 United Kingdom
Primary
Concomitant
Sepsis Hospitalization 7/20/2006 56 Male 203 lb 8/22/2006 Physician Brazil
Primary
Concomitant
Epididymitis Hospitalization 7/27/2006 Male 8/23/2006 Other Health Professional Austria
Primary
Concomitant
Lactic Acidosis Hospitalization 77 Male 8/23/2006 United Kingdom
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 8/30/2006
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2000 52 Female 143 lb 8/25/2006
Primary
Secondary
Concomitant
Tongue Discolouration Other Serious 7/20/2006 81 Male 8/29/2006 Thailand
Primary
Concomitant
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Septic Shock Other Serious 3/28/2006 73 Male 165 lb 9/1/2006 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 7/18/2006 56 Male 203 lb 9/1/2006 Brazil
Primary
Concomitant
Sepsis Hospitalization 7/18/2006 56 Male 203 lb 9/1/2006 Brazil
Primary
Concomitant
Rhabdomyolysis Other Serious 5/4/2006 52 Male 209 lb 9/6/2006 United Kingdom
Primary
Concomitant
Neck Pain Other Serious 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Yellow Skin Hospitalization 8/27/2006 69 Male 9/8/2006 Physician Austria
Primary
Concomitant
Respiratory Failure Hospitalization 5/22/2006 60 Male 9/8/2006 Netherlands
Primary
Concomitant
Tongue Discolouration Other Serious 7/20/2006 81 Male 8/30/2006 Thailand
Primary
Concomitant
Tongue Discolouration Other Serious 7/20/2006 81 Male 9/8/2006 Thailand
Primary
Concomitant
Neoplasm Progression Life Threatening 6/2/2006 Male 9/18/2006
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 52 Female 143 lb 9/7/2006 Physician Austria
Primary
Concomitant
Rhinorrhoea Hospitalization 8/8/2006 60 Male 234 lb 9/12/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Ultrasound Abdomen Abnormal Other Serious 70 Male 9/12/2006 Physician Switzerland
Primary
Concomitant
Tongue Discolouration Other Serious 7/20/2006 81 Male 9/8/2006 Thailand
Primary
Concomitant
Cardiac Arrest Death 9/13/2006 53 Female 353 lb 9/21/2006 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 9/18/2006 Other Health Professional Brazil
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Tumour Invasion Life Threatening 6/2/2006 Male 9/25/2006
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/11/2006 79 Female 154 lb 10/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 4/5/2005 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
Yellow Skin Hospitalization 8/27/2006 69 Male 9/28/2006 Physician Austria
Primary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 9/27/2006 Other Health Professional Brazil
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 79 Female 154 lb 9/29/2006 United Kingdom
Primary
Concomitant
Sudden Death Death 6/16/2006 57 Male 179 lb 10/5/2006 Physician Germany
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 74 Male 10/5/2006
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 6/18/2006 87 Male 179 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Epididymitis Hospitalization 7/27/2006 Male 10/3/2006 Physician Austria
Primary
Concomitant
Respiratory Tract Infection Other Serious 5/30/2006 74 Female 10/3/2006 Other Health Professional Sweden
Primary
Concomitant

Drug Data