Rabeprazole Sodium combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Angioneurotic Oedema Hospitalization 10/11/2005 80 Male 10/27/2005 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 8/1/2005 59 Male 1/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/21/2005 Male 1/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lacunar Infarction Other Serious 9/23/2002 72 Male 240 lb 2/22/2006 Physician United States
Primary
Concomitant
Viral Infection Hospitalization 1/1/2002 71 Male 2/27/2006 Physician Puerto Rico
Primary
Concomitant
Vascular Dementia Other Serious 9/23/2002 72 Male 240 lb 2/28/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 11/23/2004 66 Female 135 lb 12/21/2005 Consumer United States
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 11/6/2005 53 Male 12/27/2005 Consumer United States
Primary
Concomitant
Pneumonia Staphylococcal Hospitalization 8/22/2005 80 Male 191 lb 12/27/2005 Consumer United States
Primary
Concomitant
Renal Function Test Abnormal Hospitalization 7/20/2005 82 Male 3/21/2006 Physician Sweden
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 3/14/2006 Other Health Professional Austria
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/2/2006 Male 5/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 5/17/2006 Physician Austria
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 10/3/2005 42 Male 1/25/2006 United States
Primary
Concomitant
Post Procedural Vomiting Hospitalization 5/24/2006 82 Male 119 lb 8/4/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 5/24/2006 82 Male 119 lb 8/8/2006 Physician Japan
Primary
Concomitant
Pemphigus Other Serious 6/9/2006 61 Female 8/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Life Threatening 1/10/2006 Female 146 lb 9/7/2006 Physician Germany
Primary
Concomitant
Myalgia Other Serious 5/9/2006 79 Male 182 lb 9/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lethargy Other Serious 8/3/2006 72 Male 172 lb 9/28/2006 Consumer United Kingdom
Primary
Concomitant
Death Life Threatening 10/1/2006 81 Female 11/21/2006 Physician Canada
Primary
Concomitant
Vertigo Hospitalization 4/20/2006 76 Male 11/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 12/29/2006 United Kingdom
Primary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 1/24/2007 United Kingdom
Primary
Concomitant
Procedural Pain Other Serious 11/25/2006 74 Female 259 lb 3/30/2007 Consumer United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 9/21/2006 63 Female 145 lb 4/10/2007 Consumer United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 72 Male 4/19/2007
Primary
Secondary
Concomitant
Fatigue Hospitalization 72 Male 4/27/2007 United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 10/13/2000 Male 5/7/2007 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Disability 4/12/2007 71 Female 198 lb 5/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious Male 5/23/2007 Pharmacist Australia
Primary
Concomitant
Oedema Peripheral Other Serious 4/22/2007 58 Female 6/15/2007 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious Male 7/3/2007 Pharmacist Australia
Primary
Concomitant
Sepsis Hospitalization 6/11/2007 Male 101 lb 7/13/2007 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/19/2007 71 Male 132 lb 7/20/2007 Physician Japan
Primary
Secondary
Concomitant
Oesophagitis 5/22/2007 73 Male 7/19/2007 Pharmacist United States
Primary
Concomitant
Rash Papular Hospitalization 5/22/2007 76 8/10/2007 Physician France
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 8/17/2007 Physician Austria
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 Female 152 lb 8/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/20/2006 65 Female 152 lb 8/23/2007 Physician Austria
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 8/23/2007 United Kingdom
Primary
Concomitant
Syncope Hospitalization 6/8/2007 86 Female 123 lb 8/30/2007 Physician Japan
Primary
Concomitant
Interacting
Paraesthesia Disability 67 Female 9/5/2007 Physician
Primary
Concomitant
Visual Disturbance Disability 2/19/2007 67 Female 181 lb 9/12/2007 Physician
Primary
Concomitant
Pulmonary Embolism Other Serious 1/1/2004 80 Female 10/1/2007 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 7/11/2007 59 Female 10/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Disability 6/5/2005 41 Male 9/20/2007 Physician Japan
Primary
Concomitant
Rhinitis Other Serious 7/5/2007 10/10/2007 Consumer United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 99 Male 10/17/2007 Pharmacist Australia
Primary
Concomitant
Rash Vesicular Hospitalization 10/9/2007 62 Female 154 lb 11/6/2007 Other Health Professional Greece
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/19/2007 71 Male 11/16/2007 Other Health Professional France
Primary
Secondary
Concomitant
Completed Suicide Other Serious 1/10/2005 Female 176 lb 12/18/2007 Physician Japan
Primary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/21/2006 63 Female 145 lb 2/12/2008 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 3/10/2008 71 Male 165 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 8/13/2005 Female 139 lb 4/25/2008 United Kingdom
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 3/3/2008 67 Male 4/30/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Skin Reaction Death 1/23/2008 57 Female 5/5/2008 Consumer Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/29/2008 67 Male 6/9/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 9/3/2007 6/12/2008 Consumer Canada
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/29/2008 67 Male 6/12/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Pulse Absent Hospitalization Male 205 lb 6/19/2008 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 7/11/2007 65 Female 175 lb 6/9/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/11/2007 73 Female 8/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/1/2001 62 Male 205 lb 8/26/2008 Other Health Professional United States
Primary
Concomitant
Abdominal Discomfort 10/18/2007 Male 190 lb 8/27/2008 Consumer United States
Primary
Concomitant
Urticaria 4/12/2008 Female 165 lb 8/27/2008 United States
Primary
Concomitant
Rash Generalised 5/14/2008 Female 165 lb 8/27/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Death 1/9/2008 Male 223 lb 8/28/2008 United Kingdom
Primary
Concomitant
Vitamin B12 Decreased Other Serious 70 9/12/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 12/1/2001 62 Male 205 lb 9/26/2008 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 7/11/2007 65 Female 175 lb 9/12/2008 United States
Primary
Concomitant
Rectal Haemorrhage Male 10/27/2008 Physician Netherlands
Primary
Concomitant
Microsurgery To Hand Hospitalization 1/19/2006 Female 170 lb 11/3/2008 United Kingdom
Primary
Concomitant
Soft Tissue Disorder Hospitalization 1/19/2006 Female 170 lb 11/4/2008 United Kingdom
Primary
Concomitant
Congestive Cardiomyopathy Hospitalization 9/1/2008 Female 102 lb 11/24/2008 Other Health Professional Ireland
Primary
Concomitant
Rash Generalised 9/15/2008 Female 12/12/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 12/1/2006 65 Female 1/16/2009 United States
Primary
Concomitant
Rheumatoid Arthritis Death 1/9/2008 Male 223 lb 2/18/2009 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Death 12/19/2008 80 Male 149 lb 3/4/2009 Physician Japan
Primary
Secondary
Concomitant
Skin Cancer Other Serious 1/1/2004 75 Female 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Other Serious 3/12/2009 Male 4/12/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 4/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 4/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 4/8/2009 176 lb 5/15/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 44 Female 5/15/2009 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 5/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 44 Female 5/22/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Arrhythmia Life Threatening 44 Female 6/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 44 Female 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Hospitalization 4/8/2009 176 lb 6/25/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 44 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Disability 3/6/2009 75 Male 8/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Disability 3/6/2009 75 Male 8/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Angioedema Disability 3/6/2009 75 Male 8/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Disability 3/6/2009 75 Male 8/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Angioedema Disability 3/6/2009 75 Male 8/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Flushing 9/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Swollen Tongue Disability 3/6/2009 75 Male 8/18/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Angioedema Disability 3/6/2009 75 Male 8/18/2009 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination, Visual Other Serious 8/1/2009 77 Male 189 lb 9/8/2009 Physician United Kingdom
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 10/26/2009 89 Female 11/20/2009 Pharmacist Canada
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 10/26/2009 89 Female 12/21/2009 Pharmacist Canada
Primary
Concomitant
Hypokalaemia Life Threatening 44 Female 1/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 44 Female 2/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 12/23/2009 Female 163 lb 2/2/2010 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Other Serious Male 3/5/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 7/19/2003 Male 175 lb 3/29/2010 Other Health Professional Japan
Primary
Concomitant
Skin Ulcer Death 11/1/2008 78 Female 163 lb 4/1/2010 Physician United Kingdom
Primary
Concomitant
Vascular Insufficiency Other Serious 1/1/1995 57 Male 5/11/2010 United States
Primary
Secondary
Concomitant
Disease Recurrence Disability 3/5/2009 75 Male 5/6/2010 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 6/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 6/15/2010 United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 11/1/2008 78 Female 163 lb 6/24/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/18/2008 80 Male 149 lb 6/23/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/7/2010 United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 8/21/2006 51 Male 250 lb 7/8/2010 United States
Primary
Concomitant
Swollen Tongue Disability 3/6/2009 75 Male 7/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 75 Female 119 lb 7/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 6/11/2010 69 Female 207 lb 7/14/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Disorder Other Serious 1/1/2004 75 Female 119 lb 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/1/2002 68 Male 7/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 6/11/2010 69 Female 207 lb 8/3/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 84 Female 9/2/2010 Other Health Professional Denmark
Primary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Disability 1/1/2005 54 Male 194 lb 9/20/2010 United States
Primary
Concomitant
Intentional Overdose Death 79 Female 10/21/2010 Canada
Primary
Concomitant
Coronary Artery Disease Hospitalization 8/26/2010 11/2/2010 Physician Germany
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 10/23/2010 12/8/2010 Physician Japan
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 10/23/2010 12/13/2010 Physician Japan
Primary
Concomitant
Vision Blurred Hospitalization 10/23/2010 12/23/2010 Physician Japan
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 12/1/2010 62 Male 1/24/2011 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 10/23/2010 63 Female 108 lb 2/7/2011 Other Health Professional Japan
Primary
Concomitant
Depression Other Serious 8/1/2003 60 Male 200 lb 3/3/2011 Lawyer United States
Primary
Concomitant
Anhedonia Other Serious 8/1/2003 60 Male 200 lb 3/3/2011 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 2/28/2011 68 Female 155 lb 3/14/2011 Consumer United Kingdom
Primary
Concomitant
Cerebral Ischaemia Hospitalization 1/1/2007 68 Male 3/3/2011 Physician United States
Primary
Concomitant
Ageusia Other Serious 1/5/2011 72 Female 190 lb 3/21/2011 Consumer United Kingdom
Primary
Concomitant
Ageusia Other Serious 1/5/2011 72 Female 190 lb 3/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Ageusia Other Serious 72 Female 3/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypomagnesaemia Other Serious 1/1/1995 57 Male 3/28/2011 Lawyer United States
Primary
Secondary
Concomitant

Drug Data