Crestor combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rhabdomyolysis Hospitalization 76 Female 130 lb 3/24/2006 Physician Canada
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 76 Female 130 lb 4/12/2006 Physician Canada
Primary
Concomitant
Interacting
Pyrexia Other Serious 5/19/2006 71 Male 6/19/2006 Physician Singapore
Primary
Concomitant
Splenomegaly Death 7/1/2006 36 Female 7/28/2006 Physician Philippines
Primary
Concomitant
Splenomegaly Other Serious 7/1/2006 36 Female 8/3/2006 Physician Philippines
Primary
Concomitant
Red Blood Cells Urine Positive Other Serious 5/19/2006 71 Male 8/30/2006 Physician Singapore
Primary
Concomitant
Mitochondrial Myopathy Other Serious 52 Female 8/31/2006 Austria
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/26/2006 44 Male 132 lb 11/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Stent Placement Life Threatening 6/18/2006 60 Male 202 lb 1/19/2007 Physician United States
Primary
Concomitant
Pollakiuria Other Serious 72 Female 178 lb 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 9/1/2006 Male 211 lb 12/15/2006 Pharmacist United States
Primary
Concomitant
Myalgia Required Intervention 3/9/2006 76 Male 8/17/2006 Pharmacist United States
Primary
Concomitant
Polymyalgia Rheumatica Required Intervention 4/12/2007 65 Male 173 lb 6/3/2007 Consumer United States
Primary
Secondary
Urine Colour Abnormal Other Serious 5/15/2007 78 Male 8/6/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 6/13/2007 Male 117 lb 8/21/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 12/1/2006 73 Male 163 lb 8/29/2007 Consumer Brazil
Primary
Concomitant
Sepsis Other Serious 6/13/2007 Male 117 lb 8/31/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/15/2007 72 Female 10/1/2007 Pharmacist Thailand
Primary
Concomitant
Urine Colour Abnormal Other Serious 5/15/2007 78 Male 8/6/2007 Physician United States
Primary
Secondary
Concomitant
Pancreatic Abscess Life Threatening 1/30/2006 Male 176 lb 10/9/2007 Physician Denmark
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/15/2007 72 Female 10/10/2007 Pharmacist Thailand
Primary
Concomitant
Depression Other Serious 10/24/2007 Physician Denmark
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/15/2007 72 Female 10/26/2007 Pharmacist Thailand
Primary
Concomitant
Sepsis Other Serious 6/13/2007 Male 117 lb 1/11/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Insomnia Other Serious 9/1/2007 58 Male 170 lb 2/22/2008 Consumer Brazil
Primary
Secondary
Concomitant
Insomnia Other Serious 9/1/2007 58 Male 170 lb 3/12/2008 Consumer Brazil
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 41 Male 216 lb 4/4/2008 Other Health Professional Australia
Primary
Concomitant
Pain In Extremity Hospitalization 2/13/2008 67 Female 4/29/2008 United States
Primary
Concomitant
Rectal Prolapse Hospitalization 8/1/2001 Female 106 lb 5/8/2008 Consumer United States
Primary
Secondary
Rhabdomyolysis Life Threatening 1/1/2008 75 Male 7/10/2008 Physician Australia
Primary
Secondary
Concomitant
Sepsis Other Serious 6/13/2007 Male 117 lb 8/18/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Myalgia Required Intervention 12/26/2007 55 Male 215 lb 11/13/2008 Consumer United States
Primary
Secondary
Muscle Spasms 81 Male 155 lb 12/17/2008 Consumer United States
Primary
Concomitant
Nausea Male 12/17/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 46 Female 200 lb 12/18/2008 Pharmacist United States
Primary
Concomitant
Renal Function Test Abnormal Other Serious 10/5/2008 55 Male 12/19/2008 Consumer United States
Primary
Concomitant
Pain Hospitalization 12/1/2006 48 Female 235 lb 1/23/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 1/29/2009 Other Health Professional Brazil
Primary
Secondary
Concomitant
Interstitial Lung Disease Death Male 2/16/2009 Consumer Finland
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 12/1/2006 61 Male 200 lb 3/6/2009 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 6/30/2008 Female 3/12/2009 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 2/24/2009 66 Female 201 lb 3/10/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious Male 3/27/2009 Consumer Switzerland
Primary
Secondary
Concomitant
Chest Pain Other Serious 49 Male 4/1/2009 Consumer Canada
Primary
Concomitant
Movement Disorder Other Serious 10/1/2006 38 Female 180 lb 4/1/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 54 Male 200 lb 4/16/2009 Consumer United States
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 7/21/2008 Female 188 lb 5/15/2009 Physician United States
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 7/21/2008 Female 188 lb 6/3/2009 Physician United States
Primary
Concomitant
Rash Other Serious 6/21/2009 64 Male 7/13/2009 Physician Denmark
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/29/2009 84 Female 7/2/2009 Other Health Professional United States
Primary
Concomitant
Alopecia Other Serious Female 154 lb 7/9/2009 Consumer United States
Primary
Secondary
Myalgia Other Serious 9/1/2007 58 Male 170 lb 8/13/2009 Consumer Brazil
Primary
Secondary
Concomitant
Tendon Injury Other Serious Male 8/13/2009 Physician United States
Primary
Secondary
Medication Error Other Serious Male 8/20/2009 United States
Primary
Concomitant
Hyperhidrosis Female 8/22/2009 United States
Primary
Concomitant
Surgery Hospitalization 64 Male 8/20/2009 United States
Primary
Concomitant
Chromaturia Other Serious 8/6/2009 62 Male 240 lb 8/26/2009 Physician Canada
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 9/2/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 71 Female 9/8/2009 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Liver Disorder Hospitalization 6/1/2009 46 Female 10/12/2009 Physician South Africa
Primary
Concomitant
Tachycardia Hospitalization 64 Male 10/18/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 10/17/2009 United States
Primary
Concomitant
Pain Hospitalization 62 Male 10/16/2009 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 10/20/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 64 Male 201 lb 10/26/2009 United States
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 11/4/2009 United States
Primary
Concomitant
Pain 1/18/2009 72 Female 220 lb 9/21/2009 Consumer United States
Primary
Secondary
Wrong Drug Administered Life Threatening 1/1/2008 75 Male 11/23/2009 Physician Australia
Primary
Secondary
Thyroid Disorder Other Serious 60 Female 121 lb 11/16/2009 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 53 Female 11/17/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 64 Male 201 lb 11/18/2009 United States
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 11/17/2009 United States
Primary
Concomitant
X-ray Limb Abnormal Other Serious 72 Male 11/16/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/28/2005 70 Female 11/18/2009 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 53 Female 11/24/2009 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 11/1/2007 Female 117 lb 12/4/2009 Brazil
Primary
Concomitant
Thyroid Disorder Other Serious 60 Female 121 lb 12/7/2009 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 53 Female 12/10/2009 United States
Primary
Concomitant
Vomiting Hospitalization 79 Male 12/10/2009 United States
Primary
Concomitant
Pain In Extremity 50 Female 270 lb 12/15/2009 United States
Primary
Secondary
Hypoaesthesia 1/1/2008 75 Male 12/21/2009 Consumer United States
Primary
Concomitant
Somnolence 10/6/2009 Female 12/22/2009 Consumer United States
Primary
Concomitant
Pruritus Generalised 76 Female 155 lb 12/22/2009 Consumer United States
Primary
Concomitant
Blood Triglycerides Increased 49 Female 142 lb 12/22/2009 Consumer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 58 Male 12/22/2009 Physician United States
Primary
Concomitant
Pain In Extremity 73 Female 190 lb 12/22/2009 Consumer United States
Primary
Concomitant
Vasculitis Female 12/22/2009 Physician United States
Primary
Secondary
Paraesthesia Male 12/22/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 60 Female 121 lb 12/23/2009 Physician United States
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 1/12/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 72 Male 201 lb 1/11/2010 United States
Primary
Concomitant
Hypokalaemia Other Serious 12/21/2009 Female 120 lb 1/21/2010 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious Female 119 lb 1/22/2010 United States
Primary
Secondary
Weight Decreased Other Serious 72 Male 201 lb 1/20/2010 United States
Primary
Concomitant
Vomiting Hospitalization 79 Male 1/21/2010 United States
Primary
Concomitant
Weight Decreased 64 Female 1/21/2010 United States
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 1/22/2010 United States
Primary
Concomitant
Stent Placement Other Serious 11/1/2008 Female 200 lb 2/5/2010 Consumer France
Primary
Concomitant
Vertigo Hospitalization 62 Male 187 lb 2/5/2010 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 9/17/2006 Female 2/25/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/26/2005 Male 170 lb 2/26/2010 Physician United States
Primary
Concomitant
Skin Disorder Other Serious 10/10/2009 60 Female 201 lb 3/9/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/1/2007 Male 3/16/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 56 Female 170 lb 3/15/2010 Consumer United States
Primary
Secondary
Renal Failure Chronic Hospitalization 2/8/2008 Female 280 lb 3/19/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 3/25/2010 United States
Primary
Concomitant
Pain Other Serious 1/1/2007 64 Female 97 lb 2/1/2010 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 4/14/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 3/10/2010 67 Male 4/15/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 4/15/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 4/22/2010 Lawyer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 11/1/2007 68 Female 117 lb 4/29/2010 Brazil
Primary
Concomitant
Weight Decreased Other Serious 8/1/2009 52 Male 132 lb 4/30/2010 Consumer Brazil
Primary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 5/3/2010 United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/1/2008 79 Female 150 lb 5/28/2010 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 75 Male 5/25/2010 Lawyer United States
Primary
Concomitant
Liver Injury Hospitalization 1/13/2010 54 Male 183 lb 6/1/2010 Germany
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 6/15/2010 United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 195 lb 6/16/2010 Physician United States
Primary
Secondary
Vomiting Other Serious 12/1/2007 25 Female 229 lb 6/22/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 3/13/2003 66 Male 174 lb 6/23/2010 United States
Primary
Concomitant
Vomiting Hospitalization 46 Male 6/28/2010 Consumer Sweden
Primary
Secondary
Concomitant
Death Death 6/9/2010 51 Female 264 lb 6/30/2010 Consumer United States
Primary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Pain In Extremity 10/26/2007 54 Female 180 lb 7/16/2010 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 59 Male 7/19/2010 Pharmacist United States
Primary
Concomitant
Urine Odour Abnormal 1/24/2008 43 Female 163 lb 7/19/2010 Consumer United States
Primary
Concomitant
Death Death 6/9/2010 51 Female 264 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 7/28/2010 United States
Primary
Concomitant
Muscle Spasms Hospitalization 2/1/2010 66 Male 7/29/2010 Consumer Brazil
Primary
Secondary
Concomitant
Death Death 6/9/2010 51 Female 264 lb 7/30/2010 Other Health Professional United States
Primary
Concomitant
Impaired Work Ability 11/1/2006 48 Female 125 lb 7/31/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 1/1/2004 61 Female 130 lb 8/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 84 Female 8/5/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 7/1/2010 Female 8/6/2010 Physician United States
Primary
Secondary
Depression Other Serious 5/21/2010 68 Female 157 lb 8/11/2010 Physician United States
Primary
Concomitant
Myalgia Other Serious Female 8/11/2010 United States
Primary
Secondary
Myalgia Other Serious Female 8/20/2010 Consumer United States
Primary
Secondary
Vomiting Other Serious 12/1/2007 25 Female 229 lb 8/23/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 59 Male 8/23/2010 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Hospitalization 6/2/2010 51 Female 264 lb 8/25/2010 Physician United States
Primary
Concomitant
Wound Other Serious 3/13/2003 66 Male 174 lb 8/25/2010 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 12/19/2007 68 Male 179 lb 8/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 8/27/2010 United States
Primary
Secondary
Concomitant
Somnolence 8/23/2009 48 Male 270 lb 8/27/2010 United States
Primary
Secondary
Concomitant

Drug Data