Ezetimibe combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperglycaemia Hospitalization 11/9/2005 62 Male 1/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 10/5/2005 Male 10/25/2005 United States
Primary
Secondary
Musculoskeletal Stiffness Other Serious 7/1/2004 14 Male 220 lb 3/10/2006 Physician United Kingdom
Primary
Interacting
Weight Decreased Hospitalization 2/9/2006 70 Male 170 lb 4/10/2006 Physician Canada
Primary
Concomitant
Hypothyroidism Life Threatening 6/19/2005 53 Male 242 lb 6/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Panic Attack 3/1/2006 56 Female 5/23/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/12/2005 51 Female 2/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/18/2005 56 Female 5/16/2006 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/19/2006 Male 120 lb 7/30/2006 Pharmacist United States
Primary
Secondary
Pain Other Serious 3/23/2006 69 Male 190 lb 4/20/2006 United States
Primary
Secondary
Urinary Hesitation Hospitalization 7/29/2006 72 Male 219 lb 8/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased 5/22/2006 65 Female 301 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 5/7/2005 71 Female 209 lb 8/10/2006 Physician United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/6/2006 47 Male 4/18/2006 Consumer United States
Primary
Concomitant
Rhabdomyolysis Death Male 154 lb 9/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subdural Haematoma Hospitalization 3/25/2006 66 Male 231 lb 10/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Other Serious 91 Male 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Required Intervention 35 Male 11/7/2006 United States
Primary
Concomitant
Pruritus Other Serious 1/1/2006 53 Female 211 lb 11/1/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Required Intervention 10/9/2006 67 Male 11/16/2006 Consumer United States
Primary
Concomitant
Hepatitis Other Serious 9/1/2006 61 Female 130 lb 12/21/2006 Physician United States
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 7/1/2006 70 Female 1/9/2007 Consumer United States
Primary
Concomitant
Rash Maculo-papular Other Serious 12/12/2006 65 Male 229 lb 1/13/2007 Other Health Professional United States
Primary
Concomitant
Blood Pressure Increased Hospitalization 9/1/2006 83 Female 1/12/2007 Consumer United States
Primary
Concomitant
Swelling Hospitalization 1/16/2007 78 Male 194 lb 1/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vestibular Ataxia Hospitalization 7/3/2006 85 Female 187 lb 1/22/2007 United Kingdom
Primary
Concomitant
Weight Decreased 1/1/2005 72 Male 182 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 2/7/2007 74 Male 138 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Muscle Spasms Other Serious 9/1/2006 Male 211 lb 12/15/2006 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased Hospitalization 1/10/2007 72 Male 3/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 2/18/2007 72 Female 205 lb 4/17/2007 Physician United Kingdom
Primary
Concomitant
Vitamin K Deficiency Hospitalization 4/12/2007 68 Male 4/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 83 Female 12/13/2006 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasms 5/1/2006 63 Male 3/13/2007 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Death 5/15/2007 58 Male 6/5/2007 Physician Switzerland
Primary
Concomitant
Hereditary Angioedema Life Threatening 62 Male 298 lb 6/8/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1996 32 Female 4/2/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 26 Male 310 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Dyspnoea Hospitalization 6/1/2007 Male 163 lb 7/10/2007 United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 5/1/2007 61 Female 7/5/2007 Pharmacist Netherlands
Primary
Concomitant
Rhabdomyolysis Other Serious 12/26/2006 76 Male 218 lb 7/12/2007 Physician United States
Primary
Concomitant
Cerebral Ischaemia Hospitalization 7/1/2007 71 Male 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 Female 150 lb 9/10/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 8/1/2007 Male 9/18/2007 Pharmacist United States
Primary
Concomitant
Dyspnoea Exertional Disability 7/27/2007 60 Male 163 lb 9/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neck Pain Hospitalization 7/11/2007 58 Female 267 lb 9/20/2007 Consumer United States
Primary
Concomitant
Dyspnoea Exertional Disability 7/27/2007 60 Male 163 lb 9/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 8/29/2007 52 Female 321 lb 9/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Exertional Disability 7/27/2007 60 Male 9/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Myalgia 10/23/2006 65 Male 10/22/2007 Physician United States
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 7/4/2007 54 Male 246 lb 10/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 7/4/2007 Male 246 lb 10/22/2007 Physician United States
Primary
Concomitant
Wrong Drug Administered Other Serious 7/4/2007 54 Male 246 lb 11/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Death 59 Male 11/19/2007 Belgium
Primary
Secondary
Epilepsy Other Serious 39 Male 11/21/2007 Other Health Professional Germany
Primary
Concomitant
Pain Other Serious 6/19/2007 68 Male 154 lb 11/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Epilepsy Other Serious 39 Male 11/19/2007 United Kingdom
Primary
Concomitant
Epilepsy Other Serious 11/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Blood Glucose Decreased 8/6/2007 Female 252 lb 11/29/2007 Consumer United States
Primary
Concomitant
Treatment Noncompliance Life Threatening 10/11/2007 Male 145 lb 10/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 39 Male 229 lb 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Epilepsy Other Serious 39 Male 11/26/2007 United Kingdom
Primary
Concomitant
Retching 3/1/2007 37 Female 10/9/2007 Consumer United States
Primary
Concomitant
Joint Swelling 8/19/2007 Male 165 lb 12/14/2007 United States
Primary
Concomitant
Weight Decreased 1/1/2005 72 Male 182 lb 10/9/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 11/30/2007 76 Female 154 lb 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 9/8/2007 75 Female 12/17/2007 United Kingdom
Primary
Concomitant
Syncope Other Serious 11/30/2007 76 Female 154 lb 12/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram St Segment Elevation Other Serious 12/14/2007 49 Female 194 lb 12/27/2007 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 Female 150 lb 1/2/2008 Physician United States
Primary
Concomitant
Treatment Failure Life Threatening 9/23/2007 79 Male 198 lb 11/12/2007 Pharmacist United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 12/3/2007 66 Male 185 lb 12/6/2007 Pharmacist United States
Primary
Concomitant
Depression Other Serious 12/1/2007 1/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Medication Error Other Serious 7/4/2007 Male 246 lb 1/21/2008 Physician United States
Primary
Concomitant
Depression Other Serious 12/1/2007 59 Male 167 lb 1/30/2008 United Kingdom
Primary
Concomitant
Sleep Disorder Hospitalization 8/1/2006 68 Female 12/3/2007 Consumer United States
Primary
Concomitant
Blood Pressure Increased Hospitalization 9/1/2006 Female 2/18/2008 Consumer United States
Primary
Concomitant
Tenderness Other Serious 58 Male 2/27/2008 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 64 Male 258 lb 2/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2005 72 Male 182 lb 1/10/2008 Consumer United States
Primary
Concomitant
Pseudoporphyria Other Serious 65 Male 2/29/2008 United Kingdom
Primary
Concomitant
Pneumonia 12/1/2007 Female 351 lb 3/15/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/5/2007 84 Male 172 lb 3/12/2008 Pharmacist United States
Primary
Secondary
Intermittent Claudication Other Serious Male 3/17/2008 Consumer United Kingdom
Primary
Concomitant
Pain In Extremity Disability 10/1/2007 Male 4/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Carotid Artery Occlusion Hospitalization 3/27/2008 60 4/9/2008 Other Health Professional
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 3/12/2008 4/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Life Threatening 67 Female 4/7/2008 United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 Female 136 lb 4/10/2008 Physician United States
Primary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 Male 4/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Cardiogenic Shock Life Threatening 11/19/2007 64 Male 4/18/2008 Germany
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 3/27/2008 60 Male 4/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Infusion Related Reaction Hospitalization 4/1/2008 63 Male 4/30/2008 Consumer United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 9/1/2007 71 Female 5/5/2008 Germany
Primary
Concomitant
Nausea Hospitalization Female 170 lb 4/27/2008 Physician United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 5/13/2008 Physician United States
Primary
Secondary
Concomitant
Anosmia Other Serious 6/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/1/2007 Male 139 lb 6/12/2008 United States
Primary
Concomitant
Rash Papular Other Serious 4/22/2008 Female 6/17/2008 Physician United Kingdom
Primary
Concomitant
Heart Rate Increased Other Serious 5/28/2008 79 Male 6/12/2008 Consumer United States
Primary
Concomitant
Anosmia Other Serious 75 Female 136 lb 6/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ischaemic Stroke Life Threatening 5/29/2008 73 Female 6/24/2008 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 76 Female 172 lb 7/3/2008 Consumer Brazil
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/15/2008 62 Male 7/10/2008 Pharmacist United States
Primary
Secondary
Rhabdomyolysis Required Intervention 78 Male 7/1/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/24/2008 70 Male 205 lb 7/15/2008 Pharmacist United States
Primary
Secondary
Concomitant
Splenic Infarction Other Serious 2/1/2008 52 Male 170 lb 7/21/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2005 Female 136 lb 7/21/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2008 58 Female 7/25/2008 United Kingdom
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2008 Male 7/25/2008 Consumer United States
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2008 Male 8/1/2008 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 7/5/2008 Male 249 lb 8/15/2008 Physician United Kingdom
Primary
Concomitant
Full Blood Count Abnormal Other Serious 7/31/2008 Female 176 lb 8/15/2008 Consumer United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 6/1/2008 75 Male 161 lb 8/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 7/11/2008 Male 240 lb 8/21/2008 Consumer United Kingdom
Primary
Concomitant
Hyperglycaemia Hospitalization 8/1/2004 75 Female 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization Female 8/27/2008 United States
Primary
Secondary
Concomitant
Urticaria 4/12/2008 Female 165 lb 8/27/2008 United States
Primary
Concomitant
Rash Generalised 5/14/2008 Female 165 lb 8/27/2008 Consumer United States
Primary
Concomitant
Burning Sensation 7/16/2008 Female 8/29/2008 United States
Primary
Concomitant
Hyperglycaemia Hospitalization 8/1/2004 Female 9/4/2008 United States
Primary
Secondary
Concomitant
Rash Papular Other Serious 4/22/2008 Male 9/17/2008 Physician United Kingdom
Primary
Concomitant
Gastric Infection Hospitalization 7/13/2008 Male 240 lb 9/19/2008 Consumer United Kingdom
Primary
Concomitant
Asthenia 46 Male 10/2/2008 Consumer United States
Primary
Concomitant
X-ray Abnormal Hospitalization 10/2/2007 69 Male 231 lb 9/30/2008 Other Health Professional United States
Primary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/13/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tooth Infection Hospitalization 9/25/2008 72 Male 10/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 10/16/2008 Physician United States
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Hair Texture Abnormal Other Serious 8/6/2007 66 Male 179 lb 10/16/2008 Austria
Primary
Secondary
Concomitant
Tooth Abscess Life Threatening 9/30/2008 72 Male 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sensory Loss Other Serious 77 Male 10/22/2008 Canada
Primary
Concomitant
Tooth Infection Life Threatening 9/30/2008 72 Male 10/27/2008
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 11/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 11/10/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 77 Male 11/11/2008 Canada
Primary
Concomitant
Pneumonia Hospitalization 1/1/2008 Female 11/18/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Required Intervention 7/16/2008 55 Male 218 lb 7/31/2008 Pharmacist United States
Primary
Concomitant
Hyperglycaemia Hospitalization 8/1/2004 Female 149 lb 11/20/2008 United States
Primary
Secondary
Concomitant

Drug Data