Simvastatin combined with Tramadol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rales Life Threatening 11/11/2005 85 Female 1/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dizziness Other Serious 11/18/2005 76 Male 189 lb 11/18/2005 Pharmacist United States
Primary
Concomitant
Neuropathy Peripheral Required Intervention 1/15/2006 Male 400 lb 2/3/2006 Consumer United States
Primary
Concomitant
Haematocrit Decreased Hospitalization 12/28/2005 62 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/24/2005 58 Male 203 lb 12/1/2005 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 12/14/2005 86 Male 2/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 5/28/2005 68 Female 2/16/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Angioedema Hospitalization 12/10/2008 73 Female 170 lb 12/11/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 9/18/2008 67 Male 158 lb 12/26/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Postoperative Adhesion Death 1/1/2008 Female 100 lb 12/24/2008 Physician United Kingdom
Primary
Concomitant
Joint Dislocation Hospitalization 5/12/2008 Male 1/5/2009 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Peripheral Vascular Disorder Disability 3/18/2009 4/8/2009 Physician United Kingdom
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/22/2008 Female 4/14/2009 Physician United States
Primary
Concomitant
Haematuria Other Serious 9/15/2008 Male 176 lb 4/15/2009 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 5/4/2005 56 Female 175 lb 4/17/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/1/2005 35 Female 250 lb 4/17/2009 Consumer United States
Primary
Concomitant
Peripheral Vascular Disorder Disability 3/18/2009 4/17/2009 Physician United Kingdom
Primary
Concomitant
Blood Pressure Increased Other Serious 3/2/2009 4/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Flatulence Other Serious 10/1/2008 Male 192 lb 5/14/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 2/5/2001 54 Male 194 lb 5/15/2009 United States
Primary
Concomitant
Muscle Twitching Other Serious 2/18/2009 77 Female 133 lb 5/15/2009 Consumer United States
Primary
Concomitant
Dizziness Other Serious 1/1/2009 65 5/22/2009 Consumer Sweden
Primary
Concomitant
Obesity Hospitalization 3/10/2009 Female 229 lb 5/27/2009 United States
Primary
Secondary
Concomitant
Dizziness Other Serious 1/1/2009 65 6/8/2009 Consumer Sweden
Primary
Concomitant
Oropharyngeal Blistering Other Serious 1/1/2009 65 6/22/2009 Physician Sweden
Primary
Concomitant
Productive Cough Other Serious 6/1/2009 68 Female 7/9/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 Female 436 lb 7/29/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 41 Male 303 lb 7/30/2009 United States
Primary
Concomitant
Renal Failure Acute Life Threatening 6/30/2009 61 8/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 72 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 71 Female 7/22/2009 United States
Primary
Concomitant
Oesophageal Adenocarcinoma Life Threatening 8/1/2008 66 Female 8/4/2009 United Kingdom
Primary
Concomitant
Oesophageal Adenocarcinoma Life Threatening 8/1/2008 66 Female 8/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Death 60 Male 8/3/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/28/2005 71 Female 8/5/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 72 Female 8/5/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 8/14/2009 Consumer
Primary
Concomitant
Gastric Ulcer Other Serious 77 Female 8/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Haematemesis Other Serious 8/12/2009 76 Female 9/9/2009 United Kingdom
Primary
Concomitant
Respiratory Rate Increased Other Serious 8/20/2009 Female 176 lb 11/17/2009 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 70 Female 12/11/2009 United States
Primary
Concomitant
Nausea Other Serious Male 183 lb 12/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abdominal Pain Death 12/5/2009 Male 179 lb 12/24/2009 Other Health Professional Spain
Primary
Concomitant
Cerebrovascular Accident Other Serious 11/19/2009 Female 12/31/2009 Physician Switzerland
Primary
Concomitant
Oesophageal Adenocarcinoma Life Threatening 8/1/2008 66 Female 1/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 Female 137 lb 1/17/2010 Consumer Brazil
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 155 lb 1/15/2010 Physician United States
Primary
Concomitant
Oesophageal Adenocarcinoma Life Threatening 8/1/2008 66 Female 1/19/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Disability 7/1/2007 Female 1/21/2010 Physician Norway
Primary
Concomitant
Syncope Hospitalization 46 Female 1/12/2010 Lawyer United States
Primary
Concomitant
Vascular Rupture Hospitalization 70 Female 1/7/2010 United States
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 12/23/2008 78 Female 1/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 11/12/2009 Female 173 lb 1/27/2010 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/3/2009 Female 1/27/2010 Other Health Professional United States
Primary
Concomitant
Drug Dose Omission 9/1/2009 Female 160 lb 1/29/2010 Consumer United States
Primary
Concomitant
Death Death Female 2/1/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/22/2010 United States
Primary
Concomitant
Vasculitis Other Serious 1/31/2010 66 Male 325 lb 2/8/2010 Pharmacist United States
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 2/1/2010 80 Female 182 lb 2/8/2010 Physician United States
Primary
Concomitant
Surgery Hospitalization 2/3/2010 Male 2/12/2010 Physician Brazil
Primary
Concomitant
Cerebrovascular Accident Death Male 135 lb 2/17/2010 Other Health Professional United States
Primary
Concomitant
Death Death Female 2/18/2010 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 12/1/2009 71 Male 183 lb 4/6/2010 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 3/25/2010 84 Female 4/29/2010 Physician United Kingdom
Primary
Concomitant
Oesophagitis Hospitalization 2/4/2010 67 Male 224 lb 4/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 45 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Drug Level Increased Other Serious 11/24/2009 49 Male 250 lb 5/7/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Myocardial Infarction Other Serious 12/1/2009 78 Male 155 lb 5/10/2010 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 4/18/2010 50 Female 223 lb 5/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Confusional State Other Serious 3/23/2010 65 Male 172 lb 5/13/2010 Consumer United States
Primary
Concomitant
Sedation Other Serious 11/24/2009 49 Male 269 lb 5/14/2010 Consumer United States
Primary
Secondary
Concomitant
Interacting
Mood Swings Other Serious 3/1/2010 57 Female 148 lb 5/25/2010 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 4/18/2010 50 Female 223 lb 5/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Hospitalization 3/20/2010 84 Female 209 lb 5/20/2010 Other Health Professional
Primary
Concomitant
Demyelination Other Serious 65 Female 6/1/2010 Physician United Kingdom
Primary
Concomitant
Impaired Healing Hospitalization 4/12/2010 60 203 lb 6/2/2010 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2010 52 Male 400 lb 6/2/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 71 Female 79 lb 5/26/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2002 43 Male 6/1/2010 Physician United States
Primary
Concomitant
Wheezing Hospitalization 81 Male 6/2/2010 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 5/27/2010 56 Female 224 lb 6/4/2010 Pharmacist United States
Primary
Secondary
Concomitant
Tangentiality Hospitalization 4/3/2010 55 Male 182 lb 6/9/2010 Other Health Professional United States
Primary
Concomitant
Ulna Fracture Other Serious 1/1/1920 Female 6/14/2010 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 4/18/2010 50 Female 223 lb 6/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Haematochezia Other Serious 6/8/2010 86 Female 134 lb 6/30/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 60 Female 6/28/2010 Other Health Professional Denmark
Primary
Concomitant
Weight Decreased Other Serious 73 Female 6/25/2010 United States
Primary
Concomitant
Throat Irritation 5/8/2008 69 Female 7/7/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 73 Female 7/2/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 10/3/2006 52 Male 161 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Nausea 5/6/2007 54 Female 160 lb 7/13/2010 Consumer United States
Primary
Concomitant
Spinal Column Injury Other Serious 1/9/2010 88 Female 7/13/2010 Consumer United States
Primary
Concomitant
Nausea 8/18/2007 73 Female 135 lb 7/16/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 2/18/2008 66 Female 227 lb 7/16/2010 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2007 58 Male 183 lb 7/17/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Myoclonus Disability 5/15/2007 56 Female 7/21/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Periorbital Haematoma Other Serious 5/9/2010 73 Female 196 lb 7/23/2010 Consumer United States
Primary
Concomitant
Pain 5/1/2009 78 Female 145 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Female 198 lb 8/4/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 7/29/2010 55 Female 8/17/2010 Physician Thailand
Primary
Secondary
Concomitant
Shock Hospitalization 8/6/2010 64 Male 8/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/18/2008 66 Female 227 lb 8/17/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 1/16/2008 64 Female 154 lb 8/19/2010 Other Health Professional United States
Primary
Concomitant
Shock Hospitalization 8/6/2010 64 Male 8/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis 2/1/2010 51 Female 175 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
Reflux Gastritis Other Serious 10/1/2009 59 Male 9/7/2010 Physician United States
Primary
Concomitant
Reflux Gastritis Other Serious 10/1/2009 59 Male 9/14/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 9/1/2010 83 Female 9/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Demyelination Other Serious 65 Female 9/16/2010 Physician United Kingdom
Primary
Concomitant
Mood Swings Other Serious 3/1/2010 57 Female 148 lb 9/16/2010 Consumer United States
Primary
Concomitant
Periorbital Haematoma Other Serious 5/9/2010 73 Female 196 lb 9/16/2010 Consumer United States
Primary
Concomitant
Vomiting 8/27/2009 78 Female 140 lb 9/16/2010 Consumer United States
Primary
Concomitant
Withdrawal Syndrome 54 Female 9/17/2010 United States
Primary
Concomitant
Metrorrhagia 6/1/2009 65 Female 140 lb 9/17/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 3/23/2001 53 Male 219 lb 9/21/2010 United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 5/13/2009 75 Male 172 lb 9/21/2010 Physician Brazil
Primary
Concomitant
Oropharyngeal Pain 1/1/2009 81 Male 9/21/2010 Consumer
Primary
Concomitant
Pain Hospitalization 2/1/2010 65 Female 9/24/2010 Pharmacist Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 53 Female 9/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 6/1/2010 75 Male 9/28/2010 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 48 Male 9/29/2010 Consumer United States
Primary
Concomitant
Chills Other Serious 71 Female 10/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 2/1/2010 65 Female 10/10/2010 Pharmacist Netherlands
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 10/11/2010 United States
Primary
Secondary
Concomitant
Drug Ineffective 2/4/2010 47 Female 212 lb 10/11/2010 Physician United States
Primary
Concomitant
Pain 9/1/2010 85 Female 142 lb 10/11/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 71 Female 134 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Reflux Gastritis Other Serious 1/1/2006 55 Male 140 lb 10/22/2010 Physician United States
Primary
Concomitant
Speech Disorder Hospitalization 9/20/2010 61 Female 10/22/2010 Consumer United States
Primary
Concomitant
Scratch Life Threatening 11/10/2010 71 Male 190 lb 11/12/2010 Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 12/31/2008 63 Male 205 lb 11/5/2010 United States
Primary
Concomitant
Unevaluable Event Hospitalization 2/13/2008 66 Male 210 lb 11/5/2010 Lawyer United States
Primary
Concomitant
Weight Loss Poor Other Serious 1/1/2009 49 Male 254 lb 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2010 49 Female 11/24/2010 Consumer United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 9/28/2005 74 Female 11/11/2010 United States
Primary
Concomitant
Tremor Other Serious 71 Female 117 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Haemoptysis Hospitalization 1/31/2010 66 Male 325 lb 10/28/2010 Pharmacist
Primary
Concomitant
Pancreatic Carcinoma Other Serious 7/6/2010 61 Male 254 lb 12/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/1/2009 69 Male 165 lb 12/13/2010 Consumer Netherlands
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 12/14/2010 Physician United States
Primary
Concomitant
Periorbital Haematoma Other Serious 5/9/2010 73 Female 196 lb 7/23/2010 Consumer United States
Primary
Concomitant
Mood Swings Other Serious 3/1/2010 57 Female 148 lb 5/25/2010 Consumer United States
Primary
Concomitant
Demyelination Other Serious 65 Female 6/1/2010 Physician United Kingdom
Primary
Concomitant
Sinusitis Female 175 lb 11/5/2010 Other Health Professional United States
Primary
Concomitant
Nervous System Disorder Other Serious Female 12/15/2010 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 5/1/2010 65 Male 183 lb 12/16/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/13/2010 12/16/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 8/1/2010 80 Female 240 lb 12/17/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2010 68 Female 126 lb 12/21/2010 Consumer United States
Primary
Concomitant

Drug Data