Acetaminophen W/ Codeine combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Supraventricular Tachycardia Other Serious 3/5/2006 66 Female 3/20/2006 Other Health Professional Canada
Primary
Concomitant
Urethral Haemorrhage 4/18/2006 76 Male 5/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Stomach Discomfort Other Serious 3/15/2006 Male 227 lb 6/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 6/20/2006 Canada
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 7/21/2006 Canada
Primary
Concomitant
Alveolitis Hospitalization 4/1/2005 Female 231 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Life Threatening 6/4/2006 55 Male 8/10/2006
Primary
Concomitant
Blood Potassium Increased Other Serious Female 8/8/2006 Other Health Professional Denmark
Primary
Concomitant
Pulmonary Oedema Other Serious 9/4/2003 57 Female 8/21/2006 United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 8/11/2006 Canada
Primary
Concomitant
Stomach Discomfort Other Serious 3/15/2006 Male 8/18/2006 Other Health Professional Denmark
Primary
Concomitant
Large Granular Lymphocytosis Other Serious 4/11/2006 Female 9/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Clonal Evolution 4/11/2006 Female 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/15/2005 32 Male 9/26/2006 Australia
Primary
Secondary
Concomitant
Electrocardiogram T Wave Inversion Hospitalization 9/18/2006 80 Male 215 lb 10/10/2006 Physician
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/8/2006 81 Female 11/7/2006 Consumer United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 10/23/2006 Canada
Primary
Concomitant
Vasculitis Hospitalization 9/1/2006 71 Male 11/7/2006 Physician United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious 7/6/2006 Male 282 lb 11/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Synovitis Other Serious 9/4/2003 57 Female 11/17/2006 United States
Primary
Concomitant
Hypoglycaemia Other Serious 8/25/2006 Female 254 lb 10/30/2006 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 54 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Vision Blurred Hospitalization 10/26/2006 47 Male 110 lb 11/27/2006 Physician United Kingdom
Primary
Concomitant
Cardiac Hypertrophy Death 11/15/2006 51 Female 252 lb 12/11/2006 Physician United Kingdom
Primary
Concomitant
Asthenia Other Serious 1/1/2006 73 Female 12/8/2006 Physician Portugal
Primary
Secondary
Tachycardia Other Serious 7/11/2006 80 Female 2/19/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/1/2006 77 Male 3/2/2007 Physician Germany
Primary
Concomitant
Fatigue Hospitalization 72 Male 4/19/2007
Primary
Secondary
Concomitant
Fatigue Hospitalization 72 Male 4/27/2007 United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 4/18/2007 57 Male 194 lb 4/30/2007 Consumer Brazil
Primary
Concomitant
Dermatitis Infected Hospitalization 8/23/2006 Male 5/4/2007 Physician Australia
Primary
Concomitant
Metastasis Other Serious 6/20/2006 75 Female 6/18/2007 Pharmacist United Kingdom
Primary
Concomitant
Sinus Disorder Other Serious 52 Female 7/12/2007 Pharmacist United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Female 220 lb 7/13/2007 Physician United States
Primary
Secondary
Sinus Headache Other Serious 52 Female 8/2/2007 Consumer United Kingdom
Primary
Concomitant
Sleep Disorder Other Serious 5/17/2007 Male 300 lb 8/8/2007 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 8/15/2007 Female 170 lb 9/6/2007 United Kingdom
Primary
Concomitant
Myoclonus Disability 56 Female 8/30/2007 United Kingdom
Primary
Secondary
Concomitant
Myoclonus Disability 5/15/2007 56 Female 9/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 8/15/2007 Male 196 lb 11/21/2007 United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 8/15/2007 Female 170 lb 11/29/2007 United Kingdom
Primary
Concomitant
Productive Cough Other Serious 1/31/2008 71 Male 176 lb 2/29/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 50 Female 3/3/2008 United States
Primary
Concomitant
Interacting
Febrile Neutropenia Hospitalization 4/18/2007 70 Female 110 lb 3/4/2008 Physician Brazil
Primary
Secondary
Concomitant
Oropharyngeal Blistering Other Serious 1/7/2008 Male 161 lb 3/4/2008 Physician United Kingdom
Primary
Concomitant
Urine Output Decreased Hospitalization 50 Female 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 4/18/2007 Female 161 lb 4/18/2008 Consumer United Kingdom
Primary
Concomitant
Oropharyngeal Blistering Other Serious 1/7/2008 Male 161 lb 4/18/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/4/2008 Female 4/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 1/15/2008 Female 187 lb 4/24/2008 Physician United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious 3/31/2008 Female 200 lb 4/29/2008 Consumer United Kingdom
Primary
Concomitant
Blood Glucose Increased Other Serious 51 Male 151 lb 4/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Other Serious 3/1/2008 Female 194 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/4/2008 Female 5/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Mood Swings Disability 58 Female 5/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2008 50 Female 5/28/2008 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 11/1/2007 Female 167 lb 6/12/2008 Consumer United Kingdom
Primary
Concomitant
Pain In Extremity 2/1/2008 Female 200 lb 6/12/2008 Consumer United States
Primary
Concomitant
Nightmare Other Serious 5/1/2008 72 Female 123 lb 6/16/2008 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 5/1/2002 Female 6/20/2008 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 12/14/2007 Female 172 lb 6/25/2008 United Kingdom
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Female 263 lb 6/24/2008 Physician United States
Primary
Secondary
Hysterectomy Other Serious 12/15/2007 60 Female 137 lb 6/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 5/10/2008 85 Female 163 lb 7/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Limb Injury Hospitalization 8/30/2007 Male 198 lb 7/15/2008 United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2005 66 Female 7/16/2008 Physician Sweden
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 1/15/2008 Female 187 lb 7/16/2008 Physician United Kingdom
Primary
Concomitant
Hypokalaemia Other Serious 6/27/2008 Female 176 lb 7/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 7/28/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 3/15/2008 Male 245 lb 8/11/2008 United Kingdom
Primary
Concomitant
Angle Closure Glaucoma Other Serious 8/10/2008 61 Female 79 lb 9/4/2008 Physician United Kingdom
Primary
Concomitant
Pneumonia Pneumococcal Hospitalization 69 Male 9/9/2008 Consumer United Kingdom
Primary
Secondary
Tension Other Serious 1/1/2007 65 Male 9/11/2008 Consumer United Kingdom
Primary
Secondary
Angioedema Hospitalization 7/22/2008 65 Female 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Pneumococcal Other Serious 69 Male 9/10/2008 United Kingdom
Primary
Secondary
Concomitant
Self Esteem Decreased Other Serious 7/22/2008 Male 9/18/2008 Consumer United Kingdom
Primary
Concomitant
Large Intestine Perforation Hospitalization 12/1/2007 Male 9/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tension Other Serious 1/1/2007 65 Male 9/24/2008 Consumer United Kingdom
Primary
Secondary
Pancreatic Carcinoma Metastatic Life Threatening 60 Male 165 lb 10/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Life Threatening 9/17/2008 83 Female 10/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 50 Female 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Malaise Life Threatening 9/17/2008 88 Female 10/6/2008
Primary
Secondary
Concomitant
Self Esteem Decreased Other Serious 7/1/2008 Male 10/15/2008 Consumer United Kingdom
Primary
Concomitant
Tension Other Serious 1/1/2007 67 Male 10/17/2008 Consumer United Kingdom
Primary
Secondary
Lung Neoplasm Malignant Other Serious 10/20/2008 Female 176 lb 10/24/2008 Netherlands
Primary
Concomitant
Angioedema Hospitalization 7/22/2008 65 Female 10/22/2008 Other Health Professional Denmark
Primary
Concomitant
Pneumonia Death 12/11/2007 94 Female 99 lb 10/17/2008
Primary
Concomitant
Muscle Spasms Other Serious 3/15/2006 Male 10/22/2008 Denmark
Primary
Concomitant
Blood Potassium Increased Other Serious Female 10/23/2008 Other Health Professional Denmark
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 9/8/2008 Female 176 lb 10/31/2008 Netherlands
Primary
Concomitant
Pyrexia Hospitalization 1/1/2007 Male 10/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 3/8/2008 66 Female 10/29/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 6/1/2008 56 Female 11/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 9/8/2008 Female 176 lb 11/13/2008 Netherlands
Primary
Concomitant
Confusional State Other Serious 10/24/2008 75 Female 11/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious Male 11/26/2008 Consumer United Kingdom
Primary
Secondary
Haemoglobin Decreased Life Threatening 10/21/2008 86 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 9/11/2008 83 Female 12/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious 11/1/2008 85 Male 12/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious 11/1/2008 12/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 9/11/2008 83 Female 12/12/2008 Other Health Professional Denmark
Primary
Concomitant
Myositis Other Serious 11/1/2008 85 Male 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 11/21/2008 Female 12/18/2008 Physician United States
Primary
Concomitant
Hernia Other Serious 9/1/2008 Male 189 lb 12/19/2008 Consumer United Kingdom
Primary
Concomitant
Myositis Other Serious 11/1/2008 85 Male 12/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 9/11/2008 83 Female 12/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 9/11/2008 83 Female 12/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 50 Female 12/30/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Pneumococcal Hospitalization 69 Male 1/5/2009 Consumer United Kingdom
Primary
Secondary
Myositis Other Serious 11/1/2008 85 Male 1/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious 11/1/2008 1/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tension Other Serious 1/1/2007 67 Male 1/13/2009 Consumer United Kingdom
Primary
Secondary
Pneumonia Hospitalization 12/14/2007 Female 172 lb 1/15/2009 United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious 9/1/2008 64 Male 1/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 76 Female 126 lb 1/22/2009 Physician United Kingdom
Primary
Concomitant
Oesophageal Carcinoma Other Serious 54 Female 1/16/2009 Physician United Kingdom
Primary
Concomitant
Myositis Other Serious 11/1/2008 85 Male 1/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 12/2/2008 1/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myositis Disability 11/1/2008 85 Male 1/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 76 Female 1/21/2009 United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 76 Female 126 lb 1/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myositis Other Serious 11/1/2008 2/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death Male 205 lb 2/9/2009 United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious 9/1/2008 64 Male 2/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 2/16/2009 United Kingdom
Primary
Secondary
Concomitant
Syncope Death 8/18/2008 Female 214 lb 2/24/2009 Physician United Kingdom
Primary
Concomitant
Dyspnoea Death 8/18/2008 Female 214 lb 2/25/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 9/1/2008 Male 2/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Hospitalization 86 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hallucination Hospitalization 9/15/2008 Male 190 lb 3/6/2009 United Kingdom
Primary
Concomitant
Oedema Hospitalization 1/14/2009 Female 3/16/2009 Physician Sweden
Primary
Concomitant
Pericarditis Other Serious 2/11/2009 Male 264 lb 3/24/2009 Consumer United Kingdom
Primary
Concomitant
Pneumonia Pneumococcal Hospitalization 1/1/2009 69 Male 3/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 3/24/2009 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2008 70 Male 3/20/2009 Consumer United States
Primary
Concomitant
Tension Other Serious 1/1/2007 Male 4/6/2009 Consumer United Kingdom
Primary
Secondary
Type 1 Diabetes Mellitus Other Serious 4/1/2002 42 Male 175 lb 4/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 4/3/2002 42 Male 175 lb 4/6/2009 United States
Primary
Secondary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/10/2009 United Kingdom
Primary
Concomitant
Platelet Count Decreased Death 68 Male 198 lb 4/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2008 73 Male 4/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Productive Cough Other Serious 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Productive Cough Hospitalization 1/6/2009 Female 117 lb 4/17/2009 United Kingdom
Primary
Concomitant
Somnolence Hospitalization 8/16/2007 64 Female 128 lb 5/1/2009 Lawyer United States
Primary
Concomitant
Syncope Other Serious 4/30/2009 55 Female 132 lb 5/11/2009 Consumer Brazil
Primary
Concomitant
Interstitial Lung Disease Other Serious 1/1/2009 73 Female 5/11/2009 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/1/2009 73 Female 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 1/1/2009 73 Female 5/13/2009 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data