Gleevec combined with Simvastatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Death 6/28/2006 58 Male 172 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization Female 7/10/2006 Physician Denmark
Primary
Secondary
Rhabdomyolysis Hospitalization 6/26/2006 72 Female 7/17/2006 Physician Denmark
Primary
Secondary
Rhabdomyolysis Hospitalization 6/26/2006 72 Female 7/24/2006 Physician Denmark
Primary
Secondary
Cataract Operation Hospitalization 3/8/2005 62 Male 7/25/2006 Physician Netherlands
Primary
Concomitant
Weight Increased Other Serious 6/22/2006 59 Male 172 lb 10/28/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Hospitalization 1/16/2007 78 Male 194 lb 1/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization Male 1/26/2007 United States
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 1/1/2006 72 Female 3/31/2007 Physician Denmark
Primary
Secondary
Concomitant
Thyroid Operation Other Serious 1/1/2005 Male 179 lb 5/7/2007 Physician Germany
Primary
Secondary
Concomitant
Confusional State Hospitalization 8/3/2006 90 Female 108 lb 4/24/2007 Other Health Professional United States
Primary
Concomitant
Death Other Serious Male 168 lb 7/18/2007 Consumer Brazil
Primary
Concomitant
Thyroid Operation Other Serious 1/1/2005 Male 179 lb 10/2/2007 Pharmacist Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 10/2/2007 Male 170 lb 10/3/2007 United States
Primary
Secondary
Concomitant
Thrombosis Life Threatening 10/2/2007 65 Male 170 lb 10/4/2007 United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 11/1/2007 77 Male 207 lb 12/24/2007 Physician United States
Primary
Concomitant
Stent Placement Other Serious 1/1/2007 Male 3/21/2008 Physician United Kingdom
Primary
Concomitant
Injury Death 6/12/2008 Male 6/18/2008 United States
Primary
Concomitant
Injury Death 6/12/2008 Male 6/23/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2007 Male 7/15/2008 Physician United Kingdom
Primary
Concomitant
Therapy Responder Other Serious Female 8/26/2008 Physician Israel
Primary
Concomitant
Road Traffic Accident Other Serious 8/29/2008 Male 132 lb 8/6/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/1/2009 Male 170 lb 9/25/2009 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization Female 12/8/2009 United States
Primary
Concomitant
Blood Product Transfusion Dependent Other Serious 9/9/2008 Male 176 lb 12/9/2009 Physician Australia
Primary
Concomitant
Retinal Haemorrhage Other Serious 12/1/2009 1/25/2010 Consumer South Africa
Primary
Concomitant
Interacting
Ischaemic Stroke Hospitalization 12/7/2009 72 Male 2/5/2010 United States
Primary
Secondary
Concomitant
Death Death 2/1/2009 Female 3/18/2010 United States
Primary
Concomitant
Urine Output Decreased Hospitalization 2/11/2010 Female 124 lb 3/22/2010 United States
Primary
Concomitant
Renal Cancer Other Serious 1/1/2008 66 Male 4/9/2010 Physician France
Primary
Secondary
Concomitant
Renal Cancer Hospitalization Male 220 lb 4/13/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Cancer Hospitalization Male 220 lb 4/13/2010 Other Health Professional France
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 72 Male 5/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious Male 5/27/2010 Consumer United States
Primary
Concomitant
Interacting
Visual Impairment Other Serious Male 6/1/2010 Consumer United States
Primary
Concomitant
Interacting
Stress Other Serious 1/1/2010 85 Female 6/17/2010 United States
Primary
Concomitant
Swelling Other Serious 5/1/2010 61 Male 212 lb 6/21/2010 United States
Primary
Concomitant
Death Death 1/18/2010 69 Female 7/5/2010 United States
Primary
Concomitant
Stress Other Serious 1/1/2010 85 Female 7/13/2010 United States
Primary
Concomitant
Nightmare 45 Female 283 lb 7/19/2010 Consumer United States
Primary
Concomitant
Interacting
Urosepsis Hospitalization 6/23/2010 88 Male 8/6/2010 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 5/8/2009 68 Female 8/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Malabsorption Other Serious 4/1/2008 67 Male 8/26/2010 Physician United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 5/8/2009 68 Female 8/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urosepsis Hospitalization 6/23/2010 88 Male 190 lb 9/1/2010 United States
Primary
Concomitant
Renal Cancer Hospitalization 6/1/2009 66 Male 220 lb 9/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/15/2010 63 Male 10/13/2010 United States
Primary
Concomitant
Interacting
Ventricular Extrasystoles Other Serious 5/8/2009 68 Female 10/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 5/8/2009 68 Female 11/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/4/2010 70 Female 159 lb 12/15/2010 United States
Primary
Concomitant
Weight Increased Other Serious 8/4/2010 70 Female 159 lb 12/31/2010 United States
Primary
Concomitant
Blood Blister Other Serious 11/11/2010 77 Male 300 lb 2/11/2011 United States
Primary
Concomitant
Melaena Hospitalization 12/1/2010 Female 2/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death Male 2/21/2011 United States
Primary
Concomitant
Surgery Hospitalization 2/16/2011 71 Female 188 lb 2/21/2011 Physician Brazil
Primary
Secondary
Concomitant
Malaise Other Serious 11/5/2010 55 Female 126 lb 2/22/2011 United States
Primary
Concomitant
Dyspepsia Other Serious 11/5/2010 55 Female 126 lb 3/10/2011 United States
Primary
Concomitant
Nocturia Death 1/8/2011 80 Male 3/10/2011 Consumer United States
Primary
Concomitant
Blood Blister Other Serious 11/11/2010 77 Male 300 lb 3/23/2011 Pharmacist United States
Primary
Concomitant
Gastrointestinal Stromal Tumour Death Male 3/23/2011 Consumer United States
Primary
Concomitant
Fatigue Other Serious 1/1/2005 58 Male 3/24/2011 Physician United Kingdom
Primary
Concomitant
Ear Disorder Other Serious 8/4/2010 70 Female 159 lb 3/24/2011 United States
Primary
Concomitant
Haematocrit Decreased Other Serious 5/6/2008 68 Female 156 lb 3/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 1/1/2005 58 Male 4/7/2011 Physician United Kingdom
Primary
Concomitant
Subdural Haematoma Hospitalization 2/16/2011 71 Female 188 lb 4/12/2011 Physician Brazil
Primary
Secondary
Concomitant
Diarrhoea Other Serious Male 194 lb 4/21/2011 United States
Primary
Concomitant
Glycosuria Hospitalization 2/28/2011 85 Male 4/21/2011 Other Health Professional France
Primary
Concomitant
Neoplasm Progression Other Serious 11/5/2010 55 Female 126 lb 4/26/2011 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious Female 5/3/2011 Consumer United States
Primary
Concomitant
Hypercholesterolaemia Other Serious Female 5/9/2011 United States
Primary
Concomitant
Nausea Hospitalization 12/1/2010 Female 5/17/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious Female 5/23/2011 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 69 Male 6/6/2011 Consumer Germany
Primary
Concomitant
Haematochezia Other Serious 3/1/2011 64 Male 134 lb 6/7/2011 Physician United Kingdom
Primary
Concomitant
Mucosal Discolouration Other Serious 12/1/2008 64 Female 6/10/2011 Other Health Professional Sweden
Primary
Concomitant
Hypertension Life Threatening 6/4/2011 70 Female 6/20/2011 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 5/14/2011 71 Male 6/23/2011 Singapore
Primary
Concomitant
Arrhythmia Other Serious 1/1/2008 69 Male 231 lb 7/14/2011 Consumer Germany
Primary
Concomitant
Muscle Spasms 1/1/2005 61 Male 179 lb 7/26/2011 Consumer Germany
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Other Serious 4/29/2011 57 Male 253 lb 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Male 8/4/2011 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 5/14/2011 73 Male 8/5/2011 Consumer United States
Primary
Concomitant
Blood Blister Other Serious 11/11/2010 77 Male 8/22/2011 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected Male 9/6/2011 United States
Primary
Secondary
Concomitant
Dyslipidaemia Hospitalization Female 157 lb 9/9/2011 Physician United States
Primary
Concomitant
Myalgia Other Serious 1/25/2011 68 Male 229 lb 9/20/2011 Physician Germany
Primary
Concomitant
Oedema Peripheral Other Serious 2/4/2011 77 Female 104 lb 9/28/2011 Consumer United States
Primary
Concomitant
Dyspnoea Disability 6/29/2011 71 Female 10/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Anaemia Other Serious Male 10/25/2011 United States
Primary
Concomitant
Neurofibromatosis Other Serious Female 10/31/2011 United States
Primary
Concomitant
Tongue Dry Other Serious 8/29/2008 46 Male 10/31/2011 Consumer Singapore
Primary
Concomitant
Lipids Increased Other Serious Male 11/2/2011 Consumer United States
Primary
Secondary
Concomitant
Intercapillary Glomerulosclerosis Other Serious Male 271 lb 11/24/2011 United States
Primary
Concomitant
Nausea Other Serious 10/1/2010 68 Male 182 lb 11/29/2011 Physician United States
Primary
Concomitant
Lipids Increased Other Serious Male 12/8/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 10/1/2010 68 Male 185 lb 12/19/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious 2/1/2011 70 Female 1/31/2012 Consumer Australia
Primary
Concomitant
Vomiting Hospitalization 1/16/2012 85 Female 142 lb 2/2/2012 United States
Primary
Concomitant
Fatigue Death 9/1/2010 56 Male 2/6/2012 Consumer United States
Primary
Concomitant
Haematochezia Other Serious 6/15/2011 79 Male 170 lb 2/21/2012 Consumer United States
Primary
Concomitant
Feeling Abnormal Other Serious Female 2/23/2012 Consumer United States
Primary
Concomitant
Death Death Female 3/5/2012 Consumer United States
Primary
Concomitant
Death Death 2/28/2012 76 Female 3/5/2012 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 3/4/2011 83 Female 3/9/2012 Consumer United States
Primary
Concomitant
Dizziness Other Serious 6/15/2011 79 Male 170 lb 3/20/2012 United States
Primary
Concomitant
Oropharyngeal Discomfort Other Serious Female 3/27/2012 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 82 Female 3/26/2012 Consumer Singapore
Primary
Concomitant
Discomfort Other Serious 6/11/2011 76 Male 157 lb 4/4/2012 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 5/1/2008 77 Female 7/8/2009 Physician United States
Primary
Concomitant
Gout Disability 7/8/2008 76 Female 214 lb 7/8/2009 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Hospitalization 11/17/2008 72 Female 180 lb 7/8/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/17/2008 72 Female 180 lb 7/8/2009 Pharmacist United States
Primary
Concomitant
Escherichia Infection Hospitalization 86 Male 5/16/2011 Consumer United States
Primary
Concomitant
Arthralgia Disability 7/8/2008 76 Female 214 lb 7/8/2009 Consumer United States
Primary
Concomitant
Pain Hospitalization Male 5/28/2010 Physician United States
Primary
Concomitant
Dyspnoea Exertional Other Serious 9/16/2009 80 Male 154 lb 5/28/2010 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 7/31/2008 61 Female 5/28/2010 Pharmacist United States
Primary
Concomitant
Fluid Overload Hospitalization 70 Male 5/28/2010 Physician United States
Primary
Concomitant
Pain Hospitalization 5/28/2010 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 65 Male 2/7/2012 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 9/25/2009 52 Male 5/28/2010 Physician United States
Primary
Concomitant
Protein Total Decreased Other Serious 8/4/2009 60 Female 136 lb 5/28/2010 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 70 Male 205 lb 5/16/2011 Physician United States
Primary
Concomitant
Papilloedema Other Serious 1/1/2011 65 Female 132 lb 5/16/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious Female 5/2/2012 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/6/2010 67 Male 107 lb 5/16/2011 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2000 84 Male 220 lb 5/16/2011 Physician United States
Primary
Concomitant
Endotracheal Intubation Death 9/1/2009 66 Female 130 lb 5/16/2011 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 85 Male 5/16/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 3/5/2012 73 Female 304 lb 5/8/2012 Physician United States
Primary
Concomitant
Necrosis Ischaemic Other Serious 1/1/2008 68 Male 187 lb 5/16/2012 Consumer France
Primary
Secondary
Concomitant
Back Pain Other Serious Male 5/17/2012 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious Male 5/24/2012 Consumer United States
Primary
Concomitant
Death Death 7/10/2012 56 Male 7/12/2012 Consumer United States
Primary
Concomitant
Stress Other Serious 1/2010 Female 10/15/2012 Consumer Us
Primary
Concomitant
Pain In Extremity Other Serious 10/2010 Male 185 lb 3/1/2013 Consumer Country Not Specified
Primary
Concomitant
Rash Other Serious 6/15/2011 79 Male 170 lb 10/5/2012 Physician Us
Primary
Concomitant
Death Death Female 9/11/2012 Consumer Us
Primary
Concomitant
Vomiting Hospitalization 9/1/2012 69 Male 165 lb 3/8/2013 Consumer Us
Primary
Concomitant
Rash Hospitalization 5/10/2012 72 Female 11/8/2012 Consumer Us
Primary
Concomitant
Mycobacterial Infection Other Serious 6/23/2012 69 Male 11/30/2012 Consumer Country Not Specified
Primary
Concomitant
Death Death 12/30/2012 75 Male 1/7/2013 Consumer Us
Primary
Concomitant
Vomiting Other Serious Female 1/31/2013 Consumer Us
Primary
Concomitant
Pleural Effusion Other Serious Female 1/29/2013 Consumer Us
Primary
Secondary
Concomitant
Death Death 3/8/2013 93 Male 3/13/2013 Physician Us
Primary
Concomitant
Nausea Female 3/26/2013 Physician Us
Primary
Concomitant
Vomiting Other Serious 74 Female 5/18/2012 Registered Nurse Us
Primary
Concomitant
Thrombosis Hospitalization Female 4/1/2013 Physician Us
Primary
Secondary
Concomitant
Lung Neoplasm Male 4/1/2013 Pharmacist Us
Primary
Concomitant
Yellow Skin 62 Male 130 lb 4/4/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data