| Primary |
| Renal Transplant |
19.3% |
| Liver Transplant |
13.3% |
| Immunosuppression |
11.3% |
| Dermatitis Atopic |
9.0% |
| Lupus Nephritis |
7.7% |
| Immunosuppressant Drug Therapy |
6.2% |
| Prophylaxis Against Transplant Rejection |
5.8% |
| Rheumatoid Arthritis |
4.5% |
| Colitis Ulcerative |
3.3% |
| Product Used For Unknown Indication |
3.0% |
| Prophylaxis |
2.6% |
| Lung Transplant |
2.2% |
| Heart Transplant |
2.1% |
| Stem Cell Transplant |
2.0% |
| Prophylaxis Against Graft Versus Host Disease |
1.9% |
| Hypertension |
1.8% |
| Myasthenia Gravis |
1.3% |
| Nephrotic Syndrome |
1.1% |
| Graft Versus Host Disease |
0.9% |
| Asthma |
0.8% |
|
| Death |
44.5% |
| Lymphadenopathy |
6.0% |
| Thrombotic Microangiopathy |
5.4% |
| Off Label Use |
4.4% |
| Transplant Rejection |
3.8% |
| Vomiting |
3.8% |
| Tremor |
3.5% |
| Sepsis |
3.2% |
| Drug Interaction |
2.9% |
| Pneumonia |
2.4% |
| Drug Ineffective |
2.3% |
| Weight Decreased |
2.3% |
| Renal Impairment |
2.3% |
| Neutrophil Pelger-huet Anomaly Present |
2.1% |
| Septic Shock |
2.1% |
| Toxicity To Various Agents |
2.1% |
| White Blood Cell Count Increased |
1.9% |
| Pyrexia |
1.7% |
| Drug Level Increased |
1.6% |
| Kidney Fibrosis |
1.6% |
|
| Secondary |
| Immunosuppression |
14.9% |
| Renal Transplant |
14.7% |
| Prophylaxis Against Transplant Rejection |
12.0% |
| Product Used For Unknown Indication |
7.7% |
| Liver Transplant |
6.8% |
| Prophylaxis |
6.6% |
| Colitis Ulcerative |
5.2% |
| Immunosuppressant Drug Therapy |
4.9% |
| Rheumatoid Arthritis |
4.0% |
| Drug Use For Unknown Indication |
3.9% |
| Prophylaxis Against Graft Versus Host Disease |
2.8% |
| Infection Prophylaxis |
2.7% |
| Hypertension |
2.7% |
| Prophylaxis Against Renal Transplant Rejection |
2.3% |
| Burkitt's Lymphoma |
2.0% |
| Graft Versus Host Disease |
1.6% |
| Heart Transplant |
1.6% |
| Bone Marrow Conditioning Regimen |
1.5% |
| Antifungal Prophylaxis |
1.3% |
| Transplant Rejection |
1.0% |
|
| Transplant Rejection |
16.6% |
| Urinary Tract Infection |
8.1% |
| Renal Impairment |
7.3% |
| Vomiting |
6.0% |
| Thrombotic Microangiopathy |
5.6% |
| Sepsis |
5.3% |
| Liver Transplant Rejection |
5.1% |
| Pyrexia |
4.7% |
| Renal Disorder |
4.5% |
| Upper Respiratory Tract Infection |
4.5% |
| Diarrhoea |
3.8% |
| Renal Failure Acute |
3.8% |
| Kidney Transplant Rejection |
3.4% |
| Pneumonia |
3.3% |
| Renal Failure |
3.2% |
| Cytomegalovirus Infection |
3.1% |
| Urosepsis |
3.1% |
| Respiratory Failure |
2.9% |
| Neutrophil Pelger-huet Anomaly Present |
2.8% |
| Diabetes Mellitus |
2.7% |
|
| Concomitant |
| Product Used For Unknown Indication |
24.6% |
| Prophylaxis Against Graft Versus Host Disease |
8.2% |
| Infection Prophylaxis |
7.7% |
| Prophylaxis |
7.7% |
| Bone Marrow Conditioning Regimen |
7.4% |
| Prophylaxis Against Transplant Rejection |
5.7% |
| Immunosuppression |
5.2% |
| Renal Transplant |
4.9% |
| Drug Use For Unknown Indication |
4.2% |
| Rheumatoid Arthritis |
3.7% |
| Premedication |
3.1% |
| Antifungal Prophylaxis |
3.0% |
| Stem Cell Transplant |
2.5% |
| Acute Myeloid Leukaemia |
2.5% |
| Antiviral Prophylaxis |
2.2% |
| Graft Versus Host Disease |
1.9% |
| Antibiotic Prophylaxis |
1.6% |
| Hypertension |
1.5% |
| Immunosuppressant Drug Therapy |
1.4% |
| Acute Graft Versus Host Disease |
1.1% |
|
| Vomiting |
10.4% |
| Transplant Rejection |
10.3% |
| Urinary Tract Infection |
8.4% |
| Venoocclusive Liver Disease |
6.9% |
| Pyrexia |
6.8% |
| Sepsis |
5.7% |
| Thrombotic Microangiopathy |
4.8% |
| White Blood Cell Count Decreased |
4.6% |
| Renal Impairment |
4.4% |
| Renal Failure |
4.1% |
| Thrombocytopenia |
3.9% |
| Graft Versus Host Disease |
3.8% |
| Renal Failure Acute |
3.8% |
| Acute Graft Versus Host Disease |
3.7% |
| Off Label Use |
3.3% |
| Respiratory Failure |
3.3% |
| Stomatitis |
3.1% |
| Diarrhoea |
3.0% |
| Multi-organ Failure |
2.8% |
| Death |
2.8% |
|
| Interacting |
| Immunosuppression |
18.2% |
| Immunosuppressant Drug Therapy |
12.3% |
| Renal Transplant |
9.7% |
| Product Used For Unknown Indication |
9.6% |
| Hiv Infection |
7.4% |
| Drug Use For Unknown Indication |
7.0% |
| Hypertension |
5.0% |
| Prophylaxis Against Transplant Rejection |
4.8% |
| Pneumonia |
4.0% |
| Tuberculosis |
3.5% |
| Prophylaxis |
3.1% |
| Renal Failure Chronic |
2.8% |
| Lung Transplant |
2.6% |
| Liver Transplant |
2.2% |
| Aspergillosis |
1.8% |
| Antiretroviral Therapy |
1.4% |
| Upper Respiratory Tract Infection |
1.4% |
| Hepatitis C |
1.2% |
| Pulmonary Tuberculosis |
1.2% |
| Fungal Oesophagitis |
1.1% |
|
| Drug Interaction |
19.9% |
| Drug Level Increased |
12.6% |
| Transplant Rejection |
10.1% |
| Immunosuppressant Drug Level Increased |
8.7% |
| Hyperglycaemia |
6.3% |
| Renal Failure Acute |
6.3% |
| Nephropathy Toxic |
4.9% |
| Haemolytic Uraemic Syndrome |
4.2% |
| Electrocardiogram Qt Prolonged |
3.5% |
| Vomiting |
3.5% |
| Toxicity To Various Agents |
3.1% |
| Pyrexia |
2.8% |
| Overdose |
2.1% |
| Renal Impairment |
2.1% |
| Rhabdomyolysis |
2.1% |
| Wrong Technique In Drug Usage Process |
2.1% |
| Kidney Transplant Rejection |
1.4% |
| Liver Transplant Rejection |
1.4% |
| Stomatitis |
1.4% |
| Treatment Noncompliance |
1.4% |
|