Itraconazole combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urticaria Required Intervention 6/28/2005 Male 168 lb Pharmacist United States
Primary
Concomitant
Wound Infection Hospitalization 7/5/2005 65 Male 2/1/2006 Physician Spain
Primary
Secondary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 2/2/2006 Physician Spain
Primary
Secondary
Concomitant
Vitamin A Increased Required Intervention 2/25/2006 41 Male 140 lb 3/15/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 4/11/2006 Physician Spain
Primary
Secondary
Concomitant
Post Procedural Infection Hospitalization 7/5/2005 65 Male 4/26/2007 Physician Spain
Primary
Secondary
Concomitant
Skin Papilloma Other Serious 64 Male 10/15/2007
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2005 60 Male 10/16/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2005 60 Male 11/5/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2005 60 Male 11/5/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/1/1999 58 Female 11/9/2007
Primary
Secondary
Concomitant
Neuropathy Other Serious 52 Male 11/12/2007 Physician Belgium
Primary
Concomitant
Neuropathy Other Serious 52 Male 11/19/2007 Physician Belgium
Primary
Concomitant
Tinnitus Hospitalization 47 Female 3/7/2008 Pharmacist United States
Primary
Concomitant
Trismus Death 45 Male 4/21/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 31 Male 7/18/2008
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2007 52 Male 7/16/2008 Japan
Primary
Concomitant
Subcutaneous Nodule Other Serious 49 Female 1/26/2009
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 1 Male 4/24/2009 Other Health Professional United States
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 16 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 16 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Hospitalization 1/7/2008 55 5/27/2009 Physician Portugal
Primary
Concomitant
Upper Respiratory Tract Infection 16 5/21/2009 United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 6/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 13 Female 7/7/2009 Physician France
Primary
Concomitant
Interacting
Liver Transplant Rejection Death 7/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyperglycaemia Other Serious 56 Male 7/15/2009 Other Health Professional Japan
Primary
Concomitant
Interacting
Hyperglycaemia Other Serious 56 Male 7/21/2009 Other Health Professional Japan
Primary
Concomitant
Interacting
Rheumatoid Nodule Hospitalization 10/17/2007 58 Male 154 lb 7/16/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Transplant Rejection Other Serious 7/27/2009 Physician United Kingdom
Primary
Secondary
Liver Transplant Rejection Other Serious 8/7/2009 Other Health Professional United Kingdom
Primary
Interacting
Upper Respiratory Tract Infection Other Serious 16 8/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Transplant Rejection Other Serious 9/11/2009 Other Health Professional United Kingdom
Primary
Interacting
Somnambulism Other Serious 10/3/2009 53 Male 160 lb 10/7/2009 Pharmacist United States
Primary
Concomitant
Neutropenia Other Serious 17 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Other Serious 17 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 17 Male 2/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Graft Versus Host Disease Death 7/1/2009 Female 3/29/2010 Italy
Primary
Concomitant
Renal Impairment Other Serious 17 Male 3/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 3/19/2010 United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 6/28/2009 Male 3/30/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 17 Male 3/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 4/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Chronic Graft Versus Host Disease Death 7/1/2009 65 Female 4/20/2010 Italy
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/19/2009 54 Male 132 lb 6/21/2010 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 9/21/2009 37 Female 93 lb 8/9/2010 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/23/2010 66 Male 130 lb 8/13/2010 Consumer Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/17/2010 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 1/23/2010 67 Male 130 lb 8/19/2010 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 65 Female 8/20/2010
Primary
Secondary
Thrombotic Microangiopathy Other Serious 1/23/2010 67 Male 130 lb 8/24/2010 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 7/1/2009 65 Female 8/24/2010 Other Health Professional Italy
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/31/2010 Physician Japan
Primary
Concomitant
Skin Disorder Other Serious 55 Male 9/7/2010 Other Health Professional Japan
Primary
Concomitant
Chronic Graft Versus Host Disease Death 7/1/2009 65 Female 9/13/2010 Italy
Primary
Concomitant
Multi-organ Failure Hospitalization 6/24/2009 15 Male 126 lb 9/23/2010 Physician Japan
Primary
Concomitant
Skin Disorder Other Serious 1/1/2007 55 Male 9/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Disorder 4/5/2007 55 Male 10/7/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 11/3/2010 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 5/6/2010 59 Female 99 lb 11/3/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 1/17/2010 Male 168 lb 11/22/2010 Physician Japan
Primary
Concomitant
Multi-organ Failure Hospitalization 6/24/2009 15 Male 126 lb 11/23/2010 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening Male 112 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening Male 112 lb 11/24/2010 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 5/26/2010 Male 18 lb 11/24/2010 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Death 1/27/2010 55 Female 128 lb 11/29/2010 Physician Japan
Primary
Concomitant
Tendonitis Other Serious 4/5/2007 55 Male 12/10/2010 Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2010 69 Male 130 lb 12/30/2010 Physician Japan
Primary
Concomitant
Bacterial Infection Death 8/20/2009 46 Male 161 lb 1/3/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Death 8/6/2010 67 Female 110 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 8/11/2010 24 Male 141 lb 1/7/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Test Positive Death 5/1/2010 54 Female 119 lb 1/10/2011 Physician Japan
Primary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/10/2011 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 2/26/2010 56 Male 134 lb 1/10/2011 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 1/10/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Death 8/6/2010 35 Female 71 lb 1/10/2011 Physician Japan
Primary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Hospitalization 5/1/2010 54 Female 119 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 10/26/2009 59 Male 121 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Hospitalization 2/26/2010 56 Male 134 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 8/6/2010 35 Female 71 lb 1/14/2011 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2009 18 Male 137 lb 1/24/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 5/6/2010 59 Female 99 lb 1/26/2011 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 1/26/2011 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/17/2010 43 Female 119 lb 1/26/2011 Physician Japan
Primary
Concomitant
Gastroenteritis Other Serious 7/17/2007 26 Female 1/19/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Death 1/1/2010 77 Female 2/7/2011 Consumer Japan
Primary
Concomitant
Fungal Infection Hospitalization 6/24/2009 15 Male 126 lb 2/14/2011 Consumer Japan
Primary
Concomitant
Sepsis Other Serious 9/10/2009 18 Male 137 lb 2/15/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 17 Male 2/17/2011 Physician United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 7/19/2010 32 Female 108 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2011 Consumer United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 5/6/2010 59 Female 99 lb 3/3/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 3/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 3/7/2011 Consumer United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/24/2010 19 Male 115 lb 3/10/2011 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 119 lb 3/10/2011 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 17 Male 3/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutrophil Pelger-huet Anomaly Present Other Serious 20 Male 3/14/2011 Physician United States
Primary
Secondary
Weight Decreased Other Serious 17 Male 3/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Pelger-huet Anomaly Present Other Serious 20 Male 3/24/2011 Physician United States
Primary
Secondary
Neutrophil Pelger-huet Anomaly Present Other Serious 20 Male 3/24/2011 Physician United States
Primary
Secondary
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 119 lb 3/25/2011 Physician Japan
Primary
Concomitant
Neutrophil Pelger-huet Anomaly Present Other Serious 20 Male 3/28/2011 Other Health Professional United States
Primary
Secondary
Neutrophil Pelger-huet Anomaly Present Other Serious 20 Male 3/29/2011 Other Health Professional United States
Primary
Secondary
Eosinophilic Pneumonia Hospitalization 9/9/2009 36 Female 115 lb 4/6/2011 Physician Japan
Primary
Secondary
Concomitant
Toothache Hospitalization 9/21/2009 37 Female 93 lb 4/14/2011 Physician Japan
Primary
Concomitant
Drug Tolerance Other Serious 20 Male 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fungal Infection Other Serious 10/13/2009 36 Male 143 lb 4/27/2011 Physician Japan
Primary
Concomitant
Neutrophil Pelger-huet Anomaly Present Other Serious 20 Male 5/10/2011 Physician United States
Primary
Secondary
Neutrophil Pelger-huet Anomaly Present Other Serious 20 Male 5/16/2011 Physician United States
Primary
Secondary
Dysplasia Other Serious 1/1/2011 20 Male 5/16/2011 Other Health Professional United States
Primary
Secondary
Respiratory Failure Death 10/26/2009 59 Male 121 lb 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/17/2010 55 Male 168 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 7/13/2009 65 Male 176 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 2/4/2008 73 Male 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Pelger-huet Anomaly Present Other Serious 20 Male 6/16/2011 Physician United States
Primary
Secondary
Pneumonia Death 2/4/2008 73 Male 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 7/21/2010 7/5/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data