Famotidine combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 14 Male 1/13/2006 United States
Primary
Concomitant
Renal Impairment Hospitalization 3/9/2006 52 Female 4/6/2006 Physician Czech Republic
Primary
Concomitant
Pruritus Generalised Hospitalization 8/10/2006 Female 9/21/2006 Pharmacist Japan
Primary
Concomitant
Vascular Anomaly Hospitalization Female 5 lb 2/16/2007 Physician United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious Female 5 lb 6/1/2007 Physician United States
Primary
Secondary
Concomitant
Nephrectomy Required Intervention 8/21/2003 54 Male 214 lb 2/28/2005 Other Health Professional United States
Primary
Concomitant
Haematemesis Hospitalization 6/28/2006 75 Female 9/4/2007 Physician Japan
Primary
Secondary
Concomitant
Swelling Other Serious 12/4/2003 50 Male 154 lb 10/11/2007 Physician Japan
Primary
Secondary
Concomitant
Temporal Lobe Epilepsy Other Serious 4/25/2001 12 Female 104 lb 10/19/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Death 2/9/2006 66 Female 108 lb 2/20/2008 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Required Intervention 4/6/2008 65 Male 223 lb 4/14/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/13/2008 51 Male 234 lb 4/22/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Required Intervention 4/6/2008 65 Male 223 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 4/6/2008 65 223 lb 4/29/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 4/13/2008 51 Male 234 lb 5/8/2008 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 42 Female 130 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 4/3/2007 Female 229 lb 7/25/2008 Physician United States
Primary
Concomitant
Pneumomediastinum Other Serious 6/1/2007 Male 7/31/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 65 Female 8/8/2008 Physician United States
Primary
Secondary
Sinus Bradycardia Hospitalization 65 Female 8/11/2008 Physician United States
Primary
Secondary
Pneumomediastinum Other Serious 6/1/2007 Male 8/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Wound Secretion Life Threatening 5/29/2008 39 Male 143 lb 8/8/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Shock Life Threatening 5/29/2008 39 Male 143 lb 9/25/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Weight Increased Other Serious 3/31/2008 54 Male 164 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 9/27/2004 70 Female 117 lb 12/10/2008 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 3/31/2002 26 Female 123 lb 12/10/2008 Physician Japan
Primary
Secondary
Concomitant
Vesicoureteric Reflux Hospitalization 3/2/2004 Female 4/2/2009 Physician Turkey
Primary
Concomitant
Sepsis Death 1/1/2006 40 Male 4/3/2009 United States
Primary
Concomitant
Renal Impairment Other Serious 5/21/2007 52 Male 5/29/2009 Physician Japan
Primary
Concomitant
Serum Sickness Other Serious 4/30/2007 24 Female 194 lb 5/28/2009 Physician United States
Primary
Concomitant
Varicella Life Threatening 5/13/2007 18 Female 110 lb 6/8/2009 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Other Serious 11/21/2003 Male 121 lb 6/23/2009 Physician Turkey
Primary
Secondary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Ureteric Stenosis Hospitalization 11/29/2004 Male 187 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 9/16/2004 Male 198 lb 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/12/2004 Female 125 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 6/15/2009 Male 7/10/2009 Physician Japan
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 7/22/2009 Physician Japan
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 7/27/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 9/30/2008 Female 8/3/2009 Japan
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 8/10/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 8/1/2008 37 Female 118 lb 9/9/2009 Physician Japan
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 10/8/2009 Japan
Primary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 10/26/2009 Japan
Primary
Concomitant
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/19/2009 Male 11/18/2009 Pharmacist United States
Primary
Concomitant
Polymyositis Other Serious 7/27/2006 55 Male 163 lb 11/20/2009 Consumer Japan
Primary
Secondary
Concomitant
Syncope Other Serious 9/18/2009 56 Male 11/24/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Syncope Other Serious 9/18/2009 56 Male 12/4/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/23/2009 Female 140 lb 12/28/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/23/2009 Female 129 lb 1/8/2010 Physician United States
Primary
Concomitant
Stress Other Serious 10/11/2007 56 Female 98 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/11/2007 56 Female 98 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 1/24/2010 Male 200 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Gastroenteritis Viral Hospitalization 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 5/20/2010 United States
Primary
Concomitant
Pain In Extremity Other Serious 52 Female 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 3/24/2010 56 Male 190 lb 6/4/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 3/23/2010 56 Male 190 lb 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transfusion Reaction Other Serious 6/3/2006 9 Female 56 lb 6/2/2010 Physician United States
Primary
Secondary
Concomitant
Transfusion Reaction Other Serious 6/3/2006 9 Female 56 lb 6/3/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 7/1/2010 United States
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 7/12/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 7/21/2010 Physician Japan
Primary
Concomitant
Transfusion Reaction Other Serious 6/3/2006 9 Female 56 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 8/11/2010 Physician Japan
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 8/16/2010 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/17/2010 Physician Japan
Primary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 8/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Oedema Syndrome Other Serious 52 Female 8/13/2010 United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 52 Female 8/13/2010 United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/31/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/13/2009 4 Female 31 lb 9/9/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 9/13/2010 United States
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 9/27/2010 Physician Japan
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 9/27/2010 Physician Japan
Primary
Concomitant
Pneumothorax Other Serious 3/23/2010 56 Male 190 lb 10/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 3/23/2010 56 Male 190 lb 10/6/2010 Physician United States
Primary
Secondary
Concomitant
Premature Baby Congenital Anomaly 5/21/2010 Male 26 lb 10/1/2010 Other Health Professional United States
Primary
Secondary
Premature Baby Other Serious 5/21/2010 37 Female 168 lb 10/1/2010 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Premature Labour Other Serious 5/21/2010 37 Female 168 lb 10/4/2010 Other Health Professional United States
Primary
Secondary
Premature Baby Congenital Anomaly 5/21/2010 Male 26 lb 10/4/2010 Other Health Professional United States
Primary
Secondary
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 223 lb 10/28/2010 United States
Primary
Concomitant
Ear Discomfort Other Serious 2/1/2010 68 Female 132 lb 11/18/2010 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 5/26/2010 Male 18 lb 11/24/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/13/2009 4 Female 31 lb 12/20/2010 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 60 Male 12/10/2010 Other Health Professional Japan
Primary
Concomitant
Ear Discomfort Other Serious 2/1/2010 68 Female 132 lb 12/27/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 223 lb 12/29/2010 United States
Primary
Concomitant
Sepsis Life Threatening 7/28/2010 30 Female 99 lb 1/6/2011 Physician Japan
Primary
Concomitant
Haemorrhage Death 4/13/2009 4 Female 31 lb 1/7/2011 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Recurrent Death 8/6/2010 67 Female 110 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Deafness Bilateral Other Serious 2/1/2010 68 Female 132 lb 1/12/2011 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2009 18 Male 137 lb 1/24/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Hospitalization 9/30/2009 18 Female 137 lb 1/28/2011 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 9/10/2009 18 Male 137 lb 2/15/2011 Physician Japan
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 46 Female 2/28/2011 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 1/20/2011 61 Male 97 lb 2/28/2011 Consumer Japan
Primary
Secondary
Concomitant
Graft Complication Hospitalization 46 Female 3/8/2011 Other Health Professional United States
Primary
Secondary
Blood Creatinine Increased Hospitalization 12/31/2010 65 Male 165 lb 3/23/2011 Pharmacist United States
Primary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 4/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fungal Infection Other Serious 10/13/2009 36 Male 143 lb 4/27/2011 Physician Japan
Primary
Concomitant
Nausea Hospitalization 2/1/2006 3 Female 29 lb 5/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Compression Fracture Hospitalization 12/1/2010 80 Female 66 lb 5/18/2011 Physician Japan
Primary
Concomitant
Deafness Bilateral Other Serious 2/1/2010 68 Female 132 lb 6/10/2011 Physician Japan
Primary
Concomitant
Abdominal Pain Hospitalization 10/21/2007 16 Male 99 lb 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Vein Occlusion Death 9/17/2005 60 Male 119 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Death 7/28/2010 30 Female 99 lb 6/22/2011 Physician Japan
Primary
Concomitant
Lupus Nephritis Hospitalization 1/1/2011 32 Female 6/22/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Death 8/30/2002 6 Male 35 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Foot Fracture Other Serious 52 Female 6/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 8/27/2008 43 Male 131 lb 6/17/2011 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious 2/10/2010 23 Male 117 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Bacterial Infection Life Threatening 11/8/2009 15 Male 157 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertension Life Threatening 4/22/2010 13 Male 90 lb 7/5/2011 Physician Japan
Primary
Concomitant
Memory Impairment Hospitalization 2/10/2010 23 Male 117 lb 7/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 6/14/2010 7 Female 31 lb 7/8/2011 Physician Japan
Primary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 52 Female 7/12/2011 United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lupus Nephritis Hospitalization 1/1/2011 32 Female 7/13/2011 Physician Japan
Primary
Concomitant
Human Herpesvirus 6 Infection Hospitalization 3/27/2010 23 Male 117 lb 7/14/2011 Physician Japan
Primary
Secondary
Concomitant
Engraft Failure Other Serious 6/9/2010 10 Female 88 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 8/11/2009 19 Female 86 lb 7/18/2011 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 6/9/2010 10 Female 88 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Death 4/25/2009 4 Female 32 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Death 8/23/2003 11 Female 74 lb 7/20/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Density Decreased Hospitalization 10/20/2004 44 Male 168 lb 7/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pain Other Serious 52 Female 8/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 10/29/2008 34 Female 99 lb 8/3/2011 Physician Japan
Primary
Concomitant
Complex Regional Pain Syndrome Other Serious 52 Female 8/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
No Adverse Event 32 Female 8/16/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Death 2/17/2010 8/19/2011 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 2/7/2011 20 Male 196 lb 8/22/2011 Physician Japan
Primary
Concomitant
Pain Other Serious 10/12/2007 36 Female 103 lb 8/25/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data