Humira combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tuberculosis Required Intervention 37 Male 12/20/2005 Physician United States
Primary
Concomitant
Malaise Hospitalization 5/29/2007 Female 110 lb 10/17/2007 United Kingdom
Primary
Concomitant
Pain In Extremity 1/1/2006 Male 150 lb 3/15/2008 Consumer United States
Primary
Concomitant
Swelling Other Serious 1/1/2007 Female 155 lb 6/12/2008 Consumer United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 1/1/2007 Female 126 lb 9/4/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/24/2008 Male 130 lb 10/17/2008 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/24/2008 Male 130 lb 10/29/2008 Japan
Primary
Concomitant
Weight Decreased Hospitalization 5/1/2008 Male 201 lb 11/14/2008 Physician United States
Primary
Concomitant
Urticaria Hospitalization 8/30/2008 Female 84 lb 12/5/2008 Japan
Primary
Concomitant
Retinal Vein Occlusion Hospitalization 11/27/2008 71 Male 110 lb 12/16/2008 United States
Primary
Concomitant
Visual Impairment Hospitalization 11/27/2008 Male 110 lb 12/26/2008 United States
Primary
Concomitant
Joint Swelling Hospitalization 12/17/2008 Female 12/31/2008 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/24/2008 Male 130 lb 2/6/2009 Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/28/2008 Male 157 lb 2/20/2009 Japan
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Decreased 1/1/2009 Female 3/14/2009 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/28/2008 Male 157 lb 3/19/2009 Japan
Primary
Secondary
Concomitant
Suffocation Feeling Hospitalization 2/6/2009 Female 101 lb 3/20/2009 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/24/2008 Male 130 lb 4/9/2009 Japan
Primary
Concomitant
Urticaria Hospitalization 8/30/2008 Female 84 lb 4/21/2009 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/24/2008 Male 130 lb 4/30/2009 Japan
Primary
Concomitant
Tooth Abscess Hospitalization 1/16/2009 Male 125 lb 5/11/2009 Japan
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 11/27/2008 Male 110 lb 6/22/2009 Japan
Primary
Concomitant
Tendon Rupture Other Serious 6/18/2009 Male 6/26/2009 Physician Japan
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 6/15/2009 Male 7/10/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Injury Other Serious 9/30/2008 Female 7/13/2009 Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 9/30/2008 Female 7/14/2009 Japan
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 7/22/2009 Physician Japan
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 7/27/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/1/2009 Male 150 lb 7/29/2009 Canada
Primary
Concomitant
Liver Disorder Other Serious 9/30/2008 Female 8/3/2009 Japan
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 8/10/2009 Physician Japan
Primary
Secondary
Concomitant
Suffocation Feeling Hospitalization 2/6/2009 Female 101 lb 8/21/2009 Japan
Primary
Secondary
Concomitant
Suffocation Feeling Hospitalization 2/6/2009 Female 101 lb 8/25/2009 Japan
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 8/4/2009 Male 131 lb 8/28/2009 Japan
Primary
Concomitant
Completed Suicide Death 8/14/2009 Male 137 lb 8/31/2009 Japan
Primary
Concomitant
Completed Suicide Death 8/14/2009 Male 137 lb 9/4/2009 Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 10/4/2008 Male 106 lb 9/17/2009 Japan
Primary
Concomitant
Suffocation Feeling Hospitalization 2/6/2009 Female 101 lb 9/21/2009 Japan
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 8/4/2009 Male 131 lb 10/1/2009 Japan
Primary
Concomitant
Completed Suicide Death 8/14/2009 Male 137 lb 10/2/2009 Japan
Primary
Concomitant
Organising Pneumonia Other Serious 5/18/2009 Female 10/2/2009 Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/14/2009 Female 80 lb 10/8/2009 Japan
Primary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 10/8/2009 Japan
Primary
Concomitant
Vein Disorder Other Serious 9/19/2009 Female 250 lb 10/9/2009 Canada
Primary
Concomitant
Tendon Rupture Other Serious 4/1/2009 Male 10/26/2009 Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 10/4/2008 Male 106 lb 10/28/2009 Japan
Primary
Concomitant
Raynaud's Phenomenon Hospitalization 10/19/2009 Female 84 lb 10/29/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 10/27/2009 Female 130 lb 11/4/2009 Japan
Primary
Concomitant
Organising Pneumonia Other Serious 5/18/2009 Female 11/6/2009 Japan
Primary
Secondary
Concomitant
Shock Other Serious 7/1/2009 Male 150 lb 11/13/2009 Canada
Primary
Concomitant
Pseudomonas Infection Other Serious 5/18/2009 Female 12/29/2009 Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/6/2010 Female 115 lb 1/12/2010 Japan
Primary
Concomitant
Pain Other Serious 1/6/2010 Female 115 lb 1/28/2010 Japan
Primary
Secondary
Concomitant
Vomiting Death 1/7/2010 Female 1/29/2010 Physician Japan
Primary
Concomitant
Vomiting Death 1/7/2010 Female 2/9/2010 Physician Japan
Primary
Concomitant
Organising Pneumonia Other Serious 5/18/2009 Female 2/10/2010 Japan
Primary
Secondary
Concomitant
Pain Other Serious 1/6/2010 Female 115 lb 2/26/2010 Japan
Primary
Secondary
Concomitant
Organising Pneumonia Other Serious 5/18/2009 Female 3/17/2010 Japan
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 1/4/2010 Female 110 lb 3/25/2010 Japan
Primary
Secondary
Concomitant
Shock Other Serious 1/6/2010 Female 115 lb 3/26/2010 Japan
Primary
Secondary
Concomitant
Suffocation Feeling Hospitalization 10/29/2009 45 Female 4/21/2010 Japan
Primary
Concomitant
Blood Glucose Increased Hospitalization 1/4/2010 84 Female 110 lb 5/5/2010 Japan
Primary
Secondary
Concomitant
Suffocation Feeling Hospitalization 10/29/2009 45 Female 6/3/2010 Physician Japan
Primary
Concomitant
Blood Glucose Increased Hospitalization 1/4/2010 84 Female 110 lb 6/4/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 1/6/2010 67 Female 115 lb 6/17/2010 Physician Japan
Primary
Secondary
Concomitant
Suffocation Feeling Hospitalization 10/29/2009 45 Female 6/21/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 5/8/2010 72 Male 6/24/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 3/31/2010 79 Female 7/1/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 5/8/2010 72 Male 7/1/2010 Physician Japan
Primary
Concomitant
Respiratory Disorder Death 4/15/2010 54 Male 132 lb 7/2/2010 Physician Japan
Primary
Secondary
Respiratory Disorder Death 4/15/2010 54 Male 132 lb 7/2/2010 Physician Japan
Primary
Secondary
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 7/12/2010 Physician Japan
Primary
Concomitant
Respiratory Disorder Death 3/5/2010 53 Male 132 lb 7/21/2010 Physician Japan
Primary
Secondary
Respiratory Disorder Death 4/15/2010 54 Male 132 lb 7/28/2010 Physician Japan
Primary
Secondary
Interstitial Lung Disease Death 4/1/2010 52 Female 99 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/5/2010 66 Female 82 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 3/31/2010 79 Female 8/5/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 4/1/2010 52 Female 99 lb 8/13/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 8/16/2010 Physician Japan
Primary
Concomitant
Respiratory Disorder Death 4/15/2010 54 Male 132 lb 8/17/2010 Physician Japan
Primary
Secondary
Shock Other Serious 1/6/2010 67 Female 115 lb 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Life Threatening 6/26/2010 64 Female 8/20/2010 Physician Japan
Primary
Concomitant
Spondylitis Other Serious 6/2/2010 64 Female 8/27/2010 Physician Japan
Primary
Concomitant
Drug Ineffective Other Serious 2/1/2009 8/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/8/2010 72 Male 8/31/2010 Physician Japan
Primary
Concomitant
Road Traffic Accident Hospitalization 9/19/2009 66 Female 104 lb 9/13/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 8/30/2010 37 Female 198 lb 9/15/2010 Physician United Kingdom
Primary
Concomitant
Road Traffic Accident Hospitalization 9/19/2009 66 Female 104 lb 9/16/2010 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 5/8/2010 72 Male 9/20/2010 Physician Japan
Primary
Concomitant
Respiratory Disorder Death 4/15/2010 54 Male 132 lb 9/20/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 3/31/2010 79 Female 9/23/2010 Physician Japan
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 9/27/2010 Physician Japan
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 9/27/2010 Physician Japan
Primary
Concomitant
Streptococcus Test Positive Death 4/15/2010 54 Male 132 lb 10/4/2010 Physician Japan
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 9/7/2010 14 Male 103 lb 10/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Spondylitis Other Serious 6/2/2010 64 Female 10/13/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/29/2010 60 Female 10/15/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 8/29/2010 60 Female 161 lb 10/21/2010 Physician Japan
Primary
Secondary
Septic Shock Other Serious 5/8/2010 72 Male 10/27/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 8/29/2010 60 Female 161 lb 11/2/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 3/31/2010 79 Female 11/3/2010 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 5/8/2010 72 Male 11/5/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 9/9/2010 71 Female 11/9/2010 Physician Japan
Primary
Concomitant
Malignant Pleural Effusion Other Serious 8/12/2010 71 Male 11/10/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 8/29/2010 60 Female 161 lb 11/12/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 9/9/2010 71 Female 11/16/2010 Physician Japan
Primary
Concomitant
Ear Discomfort Other Serious 2/1/2010 68 Female 132 lb 11/18/2010 Physician Japan
Primary
Concomitant
Malignant Pleural Effusion Other Serious 8/12/2010 71 Male 11/22/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 9/9/2010 71 Female 11/22/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 8/1/2010 79 Female 83 lb 12/13/2010 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 5/8/2010 72 Male 12/15/2010 Physician Japan
Primary
Concomitant
Aortic Dissection Hospitalization 11/26/2010 77 Female 95 lb 12/15/2010 Physician Japan
Primary
Concomitant
Malaise Other Serious 3/13/2010 63 Female 143 lb 12/17/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 8/27/2010 60 Female 161 lb 12/18/2010 Physician Japan
Primary
Secondary
Concomitant
Ear Discomfort Other Serious 2/1/2010 68 Female 132 lb 12/27/2010 Physician Japan
Primary
Concomitant
Aortic Dissection Hospitalization 11/26/2010 77 Female 95 lb 1/5/2011 Physician Japan
Primary
Concomitant
Deafness Bilateral Other Serious 2/1/2010 68 Female 132 lb 1/12/2011 Physician Japan
Primary
Concomitant
Drug Ineffective Hospitalization 2/1/2009 1/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 12/14/2010 50 Female 126 lb 1/28/2011 Physician Germany
Primary
Concomitant
Daydreaming Hospitalization 1/1/2010 24 Female 2/9/2011 Consumer Germany
Primary
Concomitant
Cardio-respiratory Arrest Death 8/1/2010 79 Female 83 lb 2/17/2011 Physician Japan
Primary
Concomitant
Respiratory Disorder Hospitalization 4/6/2010 62 Male 117 lb 2/23/2011 Physician Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/10/2010 47 Male 4/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/10/2010 47 Male 4/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Localised Infection Other Serious 3/4/2011 58 Female 5/9/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Hospitalization 11/22/2010 56 Male 139 lb 5/12/2011 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Other Serious 3/4/2011 58 Female 5/13/2011 Physician Japan
Primary
Secondary
Concomitant
Compression Fracture Hospitalization 12/1/2010 80 Female 66 lb 5/18/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/6/2010 62 Male 117 lb 5/23/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/22/2010 56 Male 139 lb 5/24/2011 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 4/1/2010 52 Female 99 lb 6/2/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/4/2011 67 Female 6/7/2011 Physician Japan
Primary
Concomitant
Haemorrhage Subcutaneous Hospitalization 6/1/2010 69 Male 137 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 6/1/2010 69 Male 137 lb 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Deafness Bilateral Other Serious 2/1/2010 68 Female 132 lb 6/10/2011 Physician Japan
Primary
Concomitant
Peripheral Embolism Hospitalization 5/3/2011 87 Male 6/13/2011 Physician Australia
Primary
Concomitant
Dna Antibody Positive Hospitalization 11/22/2010 56 Male 139 lb 6/13/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 8/20/2010 64 Female 6/20/2011 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 3/4/2011 58 Female 71 lb 6/22/2011 Physician Japan
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 12/17/2010 49 Female 137 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 3/1/2011 67 Female 84 lb 6/28/2011 Physician Japan
Primary
Secondary
Concomitant
Crohn's Disease Other Serious 4/18/2011 41 Female 97 lb 6/28/2011 Physician Germany
Primary
Concomitant
Adverse Drug Reaction Other Serious 3/1/2011 67 Female 84 lb 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Aortic Dissection Hospitalization 11/26/2010 77 Female 95 lb 7/6/2011 Physician Japan
Primary
Concomitant
Embolism Hospitalization 5/3/2011 87 Male 7/11/2011 Physician Australia
Primary
Concomitant
Wound Infection Other Serious 6/3/2010 57 Female 71 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Embolism Hospitalization 5/3/2011 87 Male 7/25/2011 Physician Australia
Primary
Concomitant
Dna Antibody Positive Hospitalization 11/22/2010 56 Male 139 lb 8/19/2011 Physician Japan
Primary
Concomitant
Liver Disorder Death 4/15/2010 54 Male 132 lb 9/21/2011 Physician Japan
Primary
Secondary
Concomitant
Erythrodermic Psoriasis Hospitalization 9/21/2010 46 Male 126 lb 9/21/2011 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data