Lansoprazole combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Urticaria Required Intervention 6/28/2005 Male 168 lb Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/20/2005 Female 9/22/2005 United States
Primary
Concomitant
Prurigo Hospitalization 7/28/2005 Female 2/8/2006 Physician Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 1/1/2004 68 Female 2/3/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization Female 3/13/2006 Physician United Kingdom
Primary
Concomitant
Pyloric Stenosis Hospitalization 7/28/2005 Female 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 1/8/2005 69 Female 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Required Intervention 12/2/2005 60 Male 161 lb 12/29/2005 United States
Primary
Concomitant
Rash Pruritic Required Intervention 11/23/2005 60 Male 12/1/2005 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/2/2006 66 198 lb 7/11/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2006 Male 7/19/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 8/7/2005 64 Male 7/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/26/2005 52 Female 7/24/2006 United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 4/20/2006 Male 219 lb 4/21/2006 Pharmacist United States
Primary
Concomitant
Septic Shock Life Threatening 8/28/2006 76 Female 77 lb 9/15/2006 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 8/28/2006 76 Female 77 lb 10/3/2006 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 8/28/2006 76 Female 77 lb 10/3/2006 Physician Japan
Primary
Concomitant
Pneumonia Death 7/22/2006 80 Male 136 lb 10/3/2006 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Death 2/1/2006 74 Female 9/29/2006 Physician Japan
Primary
Concomitant
Respiratory Disorder Other Serious 42 Male 11/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Death 2/1/2006 74 Female 11/21/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 42 Male 12/4/2006 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Required Intervention 8/1/2006 Male 8/7/2006 Pharmacist United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/2/2007 52 Female 134 lb 1/17/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/2/2007 52 Female 134 lb 1/24/2007 United States
Primary
Concomitant
Staphylococcal Infection Life Threatening 1/31/2006 68 Male 146 lb 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 3/8/2007 11 Female 53 lb 3/30/2007 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 12/27/2006 Male 211 lb 1/5/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/12/2006 39 Male 186 lb 8/31/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Death 7/22/2006 80 Male 136 lb 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 3/26/2007 53 Male 143 lb 4/13/2007 Physician Japan
Primary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Life Threatening 4/3/2005 54 Male 5/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 3/26/2007 53 Male 143 lb 6/4/2007 Physician Japan
Primary
Concomitant
Staphylococcal Infection Life Threatening 1/31/2006 68 Male 146 lb 6/1/2007 Physician Japan
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/30/2007 Female 31 lb 6/28/2007 Pharmacist United States
Primary
Concomitant
Angioedema Hospitalization 10/31/2006 60 Female 203 lb 7/27/2007 Physician France
Primary
Secondary
Concomitant
Serum Sickness Hospitalization 8/23/2006 53 Male 277 lb 1/15/2007 Physician United States
Primary
Concomitant
Biliary Anastomosis Complication Hospitalization 10/31/2006 60 Female 203 lb 8/1/2007 Physician France
Primary
Secondary
Concomitant
Sudden Death Death 3/26/2007 53 Male 143 lb 7/17/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 6/4/2007 31 Female 139 lb 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
Perinephric Effusion Hospitalization 3/13/2006 47 Female 1/15/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 107 lb 6/11/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/17/2007 55 Female 133 lb 5/29/2007 United States
Primary
Concomitant
Renal Failure Acute Required Intervention 3/12/2007 58 Male 225 lb 3/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Colitis Ulcerative Hospitalization 1/7/2007 21 Male 114 lb 2/1/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/2/2007 75 Female 101 lb 9/4/2007 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious 5/30/2007 Female 31 lb 9/17/2007 Pharmacist
Primary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 31 Female 139 lb 9/18/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/1/1998 26 Male 146 lb 10/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 10/27/2006 84 Female 113 lb 11/5/2007 Physician Japan
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 9/29/2005 58 Male 181 lb 11/5/2007 Physician Japan
Primary
Concomitant
Microangiopathic Haemolytic Anaemia Hospitalization 5/2/1998 26 Male 11/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 10/5/2006 9 Female 41 lb 11/24/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 10/5/2006 9 Female 40 lb 12/2/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 9 Female 41 lb 11/29/2007 United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/5/2006 9 Female 41 lb 12/1/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 10/27/2006 84 Female 113 lb 11/26/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 10/5/2006 9 Female 41 lb 11/30/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Life Threatening 2/24/2006 Female 76 lb 11/26/2007 Physician Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 11/6/2007 Female 115 lb 11/15/2007 Pharmacist United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 10/27/2006 84 Female 113 lb 1/18/2008 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 65 Male 3/6/2008
Primary
Secondary
Concomitant
Tinnitus Hospitalization 47 Female 3/7/2008 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Hospitalization 70 Female 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Life Threatening 10/6/2005 Male 143 lb 3/17/2008 Physician Japan
Primary
Secondary
Concomitant
Underdose Other Serious 6/4/2007 55 Female 110 lb 4/2/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased 5/2/2007 75 Female 101 lb 4/21/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 31 Female 139 lb 4/28/2008 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 1/1/2008 33 Female 110 lb 5/12/2008 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 5/1/2007 Female 5/29/2008 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/19/2008 3/26/2008 Pharmacist United States
Primary
Concomitant
Tremor Life Threatening 5/15/2008 Male 207 lb 5/23/2008 Pharmacist United States
Primary
Concomitant
Suicide Attempt Hospitalization 1/1/2008 33 Female 110 lb 6/17/2008 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 5/1/2007 Female 6/27/2008 Physician Canada
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 5/1/2007 Female 7/28/2008 Physician Canada
Primary
Secondary
Concomitant
Pneumomediastinum Other Serious 6/1/2007 Male 7/31/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 12/21/2005 82 Female 7/28/2008 Physician Japan
Primary
Concomitant
Streptococcal Infection Other Serious 10/12/2005 64 Female 93 lb 8/6/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 33 Male 8/13/2008 Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 33 Male 9/4/2008 Consumer Italy
Primary
Secondary
Pulmonary Fibrosis Other Serious 10/12/2005 63 Female 68 lb 8/27/2008 Physician Japan
Primary
Secondary
Concomitant
Streptococcal Infection Other Serious 10/12/2005 63 Female 68 lb 9/2/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 33 Male 9/5/2008 Italy
Primary
Secondary
Wound Infection Staphylococcal Other Serious 5/1/2007 Female 9/23/2008 Physician Canada
Primary
Secondary
Concomitant
Thrombosis Hospitalization 8/4/2005 15 Male 159 lb 9/26/2008 Physician United States
Primary
Concomitant
Nephrotic Syndrome Hospitalization 6/28/2006 Female 101 lb 10/6/2008 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 30 Female 126 lb 10/15/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/26/2007 57 146 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 8/4/2005 15 Male 159 lb 11/18/2008 Physician United States
Primary
Concomitant
Lethargy Hospitalization 10/20/2008 48 Female 10/20/2008 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased Required Intervention 5/31/2008 51 Male 150 lb 6/24/2008 Pharmacist United States
Primary
Concomitant
Pain In Extremity Required Intervention 9/6/2008 58 Female 172 lb 10/3/2008 United States
Primary
Concomitant
Mononeuropathy Multiplex Other Serious 4/20/2008 Female 110 lb 11/24/2008 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 8/18/2008 54 Male 8/25/2008 Pharmacist United States
Primary
Concomitant
Urticaria Hospitalization 8/30/2008 Female 84 lb 12/5/2008 Japan
Primary
Concomitant
Hallucination Other Serious 69 Male 12/12/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 11/27/2008 Male 110 lb 12/26/2008 United States
Primary
Concomitant
Thrombotic Stroke Hospitalization 1/30/2008 64 Female 102 lb 1/12/2009 Pharmacist Japan
Primary
Concomitant
Somnolence Other Serious 11/21/2007 59 Female 95 lb 2/3/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/4/2005 15 Male 159 lb 3/13/2009 Physician United States
Primary
Concomitant
Sepsis Death 1/1/2006 40 Male 4/3/2009 United States
Primary
Concomitant
Urticaria Hospitalization 8/30/2008 Female 84 lb 4/21/2009 Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/24/2008 61 Male 251 lb 1/7/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/2/2009 Male 186 lb 2/12/2009 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Life Threatening 5/18/2002 65 Female 5/5/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Death 4/2/2009 64 Male 174 lb 5/20/2009 Other Health Professional Japan
Primary
Concomitant
Visual Impairment Hospitalization 11/27/2008 Male 110 lb 6/22/2009 Japan
Primary
Concomitant
Wound Infection Hospitalization 4/2/2004 Female 220 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 11/1/2004 Male 141 lb 6/23/2009 Physician Turkey
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/2/2004 Male 141 lb 6/23/2009 Physician Turkey
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 4/2/2009 39 Female 110 lb 4/28/2009 Pharmacist United States
Primary
Concomitant
Respiratory Distress Hospitalization 4/20/2009 59 Male 196 lb 4/22/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 1/2/2007 52 Female 134 lb 8/7/2009 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 66 Male 207 lb 9/1/2009 Physician Italy
Primary
Concomitant
Pyrexia Required Intervention 6/21/2009 55 Male 202 lb 7/14/2009 Pharmacist United States
Primary
Concomitant
Laboratory Test Abnormal Life Threatening 8/24/2009 Female 169 lb 8/24/2009 United States
Primary
Concomitant
Somnolence Life Threatening 8/26/2009 65 Male 8/27/2009 Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 11/4/2008 39 Male 11/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/20/2009 67 Female 135 lb 7/17/2009 Pharmacist United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 49 Female 99 lb 10/6/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2008 Female 10/23/2009 Physician Japan
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 10/6/2006 50 Male 148 lb 10/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 66 Male 207 lb 11/4/2009 Physician Italy
Primary
Concomitant
Application Site Cellulitis Hospitalization 11/8/2009 Male 171 lb 11/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 12/14/2009 Male 101 lb 12/24/2009 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Life Threatening 9/27/2009 51 Female 130 lb 10/2/2009 United States
Primary
Concomitant
Methaemoglobinaemia Hospitalization 12/14/2009 Male 101 lb 1/5/2010 Physician United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 2/4/2008 39 Female 97 lb 12/24/2009 Physician Japan
Primary
Concomitant
Pyoderma Life Threatening 8/24/2009 80 Male 119 lb 12/28/2009 Physician Japan
Primary
Concomitant
Traumatic Fracture Hospitalization 12/11/2007 41 Female 12/30/2009 Physician Japan
Primary
Secondary
Concomitant
Methaemoglobinaemia Hospitalization 12/14/2009 Male 101 lb 1/11/2010 Physician United States
Primary
Secondary
Concomitant
Stress Other Serious 10/11/2007 56 Female 98 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/11/2007 56 Female 98 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/14/2009 56 Female 136 lb 1/21/2010 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/14/2009 56 Female 136 lb 2/12/2010 United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 2/4/2008 39 Female 97 lb 3/3/2010 Physician Japan
Primary
Concomitant
Pneumonia Death 1/12/2010 69 Male 214 lb 1/13/2010 Pharmacist United States
Primary
Concomitant
Infusion Related Reaction Other Serious 1/6/2010 22 Female 125 lb 1/26/2010 Pharmacist United States
Primary
Concomitant
Thrombosis Hospitalization 10/28/2009 Male 171 lb 3/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 6/28/2009 Male 3/30/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/1/2007 47 Female 3/24/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data