Pantoprazole combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transplant Rejection Hospitalization 58 Female 12/29/2005 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Required Intervention 10/1/2005 58 Female 1/16/2006 Physician United States
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome 11/20/2005 49 Male 1/23/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 9/6/2005 66 Male 1/9/2006 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/9/2006 Male 294 lb 1/22/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 9/9/2006 Male 294 lb 1/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Drug Level Increased 3/26/2007 41 Male 4/26/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/12/2005 62 Male 192 lb 2/7/2008 Physician United States
Primary
Secondary
Concomitant
Procedural Pain 12/21/2007 26 Female 6/10/2008 Physician United States
Primary
Concomitant
Respiratory Distress Other Serious 8/13/2008 69 Female 9/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 1/7/2009 Lawyer United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 194 lb 1/7/2009 Lawyer United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Recurrent Other Serious 7/18/2007 Male 1/29/2009 Physician Germany
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 45 Male 2/12/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 45 Male 2/23/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/8/2008 2/25/2009 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/20/2009 Male 194 lb 4/9/2009 Physician Canada
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/8/2008 48 Male 5/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vein Disorder Other Serious 9/19/2009 Female 250 lb 10/9/2009 Canada
Primary
Concomitant
Renal Tubular Necrosis Other Serious 5/1/2009 Female 12/7/2009 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 234 lb 12/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 1/1/2009 Male 155 lb 12/29/2009 Physician Germany
Primary
Concomitant
Urosepsis Other Serious 12/1/2009 Male 157 lb 1/11/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urosepsis Other Serious 11/27/2009 Male 157 lb 1/15/2010 Physician Netherlands
Primary
Secondary
Concomitant
Urosepsis Other Serious 11/27/2009 Male 157 lb 1/19/2010 Physician Netherlands
Primary
Secondary
Concomitant
Urosepsis Other Serious 12/11/2009 Male 157 lb 1/19/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urosepsis Other Serious 11/27/2009 Male 157 lb 1/20/2010 Physician Netherlands
Primary
Secondary
Concomitant
Death Death Male 1/20/2010 Physician Germany
Primary
Concomitant
Urosepsis Other Serious 11/27/2009 Male 157 lb 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Urosepsis Other Serious 11/27/2009 Male 157 lb 1/28/2010 Physician Netherlands
Primary
Secondary
Concomitant
Intestinal Infarction Death 9/1/2009 71 Male 2/2/2010 Physician Germany
Primary
Concomitant
Urosepsis Other Serious 12/28/2009 Male 157 lb 2/5/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Lactic Acidosis Life Threatening 12/18/2007 36 Male 159 lb 2/11/2010 Other Health Professional Germany
Primary
Concomitant
Vitamin D Deficiency Hospitalization 45 Male 2/15/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 58 Female 3/9/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 56 Male 3/5/2010 Canada
Primary
Secondary
Concomitant
Intestinal Infarction Other Serious 9/30/2009 71 Male 3/25/2010 Physician Germany
Primary
Concomitant
Septic Shock Life Threatening 10/11/2008 48 Male 4/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urosepsis Other Serious 11/27/2009 70 Male 157 lb 5/12/2010 Physician Netherlands
Primary
Secondary
Concomitant
Blood Bilirubin Increased 1/1/2008 70 Male 5/19/2010 Pharmacist United States
Primary
Secondary
Hypotension Death Female 5/21/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 46 Female 176 lb 5/24/2010 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/1/2010 38 Female 6/15/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/1/2010 38 Female 6/16/2010 Other Health Professional United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 55 Female 6/17/2010 Other Health Professional Austria
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/30/2008 56 Male 159 lb 6/22/2010 Physician Canada
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 6/15/2010 64 Female 174 lb 6/22/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/7/2010 46 Female 176 lb 7/12/2010 Pharmacist United States
Primary
Concomitant
Orthopnoea Hospitalization 7/20/2010 49 Female 212 lb 7/31/2010 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 8/4/2010 Other Health Professional Algeria
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/22/2010 55 Male 189 lb 8/10/2010 Other Health Professional United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 1/3/2010 24 Female 143 lb 8/31/2010 Pharmacist United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 1/3/2010 24 Female 143 lb 9/7/2010 Pharmacist United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 41 Male 9/1/2010 Pharmacist United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 1/3/2010 24 Female 143 lb 9/30/2010 Pharmacist United States
Primary
Concomitant
Cardiomyopathy Other Serious 9/22/2010 25 Female 120 lb 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 1/3/2010 24 Female 143 lb 10/8/2010 Pharmacist United States
Primary
Concomitant
Cardiomyopathy Other Serious 9/22/2010 25 Female 119 lb 10/13/2010 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 9/22/2010 25 Female 120 lb 10/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transmission Of An Infectious Agent Via A Medicinal Product Other Serious 7/9/2010 65 Female 164 lb 10/1/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Ischaemia Hospitalization 10/25/2010 Male 11/10/2010 Pharmacist United States
Primary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 234 lb 11/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 1/1/1998 63 Male 234 lb 11/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2009 12/9/2010 Other Health Professional Australia
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 10/15/2010 54 Male 12/23/2010 Physician United States
Primary
Concomitant
Transplant Rejection Hospitalization 4/1/2008 62 Male 12/29/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombosis Other Serious 8/1/2008 Male 12/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Other Serious 11/1/2009 65 Female 99 lb 1/5/2011 Physician Germany
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious 11/1/2009 65 Female 99 lb 1/21/2011 Physician Germany
Primary
Secondary
Concomitant
Arthralgia Other Serious 8/1/2008 Male 1/27/2011 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2009 53 Male 110 lb 2/3/2011 Other Health Professional Australia
Primary
Concomitant
Gastroenteritis Hospitalization 1/28/2011 37 Male 167 lb 2/8/2011 Physician Australia
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/28/2011 37 Male 167 lb 2/21/2011 Physician Australia
Primary
Secondary
Concomitant
Clostridial Infection Death 10/15/2010 54 Male 250 lb 3/11/2011 Physician United States
Primary
Concomitant
Pyrexia Other Serious 8/1/2008 Male 3/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 58 Male 209 lb 3/22/2011 Physician United States
Primary
Concomitant
Gastroenteritis Other Serious 1/28/2011 37 Male 167 lb 3/28/2011 Physician Australia
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 12/31/2010 65 Male 165 lb 3/23/2011 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 8/1/2008 Male 4/8/2011 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/28/2011 37 Male 167 lb 4/8/2011 Physician Australia
Primary
Secondary
Concomitant
Convulsion Hospitalization 6/3/2010 68 Male 5/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bursitis Hospitalization 8/1/2008 43 Male 5/19/2011 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 5/25/2011 8 Female 80 lb 5/27/2011 Physician United States
Primary
Concomitant
Peripheral Embolism Hospitalization 5/3/2011 87 Male 6/13/2011 Physician Australia
Primary
Concomitant
Tumour Pain Hospitalization 11/16/2010 63 Male 146 lb 6/21/2011 Physician Netherlands
Primary
Secondary
Concomitant
Metastatic Squamous Cell Carcinoma Hospitalization 12/30/2010 58 Male 6/21/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Lung Cancer Metastatic Hospitalization 11/16/2010 63 Male 146 lb 6/23/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Disorder Hospitalization 8/1/2008 43 Male 6/27/2011 Lawyer United States
Primary
Secondary
Concomitant
Crohn's Disease Other Serious 4/18/2011 41 Female 97 lb 6/28/2011 Physician Germany
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 8/1/2008 43 Male 166 lb 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Lung Cancer Metastatic Hospitalization 11/16/2010 63 Male 146 lb 7/8/2011 Physician Netherlands
Primary
Secondary
Concomitant
Embolism Hospitalization 5/3/2011 87 Male 7/11/2011 Physician Australia
Primary
Concomitant
Pancytopenia Other Serious 5/20/2011 59 Male 7/15/2011 Other Health Professional France
Primary
Secondary
Concomitant
Gynaecomastia Other Serious 10/1/2010 70 Male 7/15/2011 Consumer Netherlands
Primary
Concomitant
Embolism Hospitalization 5/3/2011 87 Male 7/25/2011 Physician Australia
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 12/30/2010 58 Male 8/16/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Localised Infection Other Serious 8/1/2008 43 Male 166 lb 8/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 1/27/2011 52 Male 187 lb 9/2/2011 Other Health Professional France
Primary
Concomitant
Interacting
Ischaemic Stroke Other Serious 62 10/7/2011 Other Health Professional Italy
Primary
Secondary
Neutropenia Hospitalization 9/12/2011 50 Male 10/13/2011 Other Health Professional France
Primary
Secondary
Concomitant
Haematochezia Hospitalization 4/18/2011 41 Female 106 lb 10/20/2011 Physician Germany
Primary
Concomitant
Haematochezia Hospitalization 4/18/2011 41 Female 106 lb 10/24/2011 Physician Germany
Primary
Concomitant
Tendonitis Life Threatening 4/16/2011 54 Male 143 lb 11/9/2011 Physician Australia
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 4/1/2008 62 Male 11/21/2011 Germany
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 4/1/2008 62 Male 11/29/2011 Germany
Primary
Secondary
Concomitant
Night Sweats Other Serious 4/18/2011 41 Female 106 lb 12/9/2011 Physician Germany
Primary
Concomitant
Neutropenia Hospitalization 9/12/2011 50 Male 12/15/2011 Other Health Professional France
Primary
Secondary
Concomitant
Immune System Disorder Other Serious 11/10/2011 68 Female 12/15/2011 United States
Primary
Concomitant
Transplant Rejection Hospitalization 12/16/2011 63 Male 172 lb 1/2/2012 Germany
Primary
Secondary
Concomitant
Malaise Hospitalization 3/22/2011 35 Female 1/6/2012 Physician Australia
Primary
Concomitant
Pneumonia Other Serious 1/20/2012 34 Female 118 lb 1/24/2012 Pharmacist United States
Primary
Concomitant
Transplant Rejection Hospitalization 12/16/2011 63 Male 172 lb 1/25/2012 Germany
Primary
Secondary
Concomitant
Dysarthria Other Serious 59 Female 2/2/2012 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 11/14/2011 62 Female 186 lb 2/16/2012 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 11/14/2011 62 Female 186 lb 2/21/2012 Physician Germany
Primary
Concomitant
Transplant Failure Life Threatening 5/16/2011 66 Male 201 lb 3/16/2012 Physician Germany
Primary
Concomitant
Endocarditis Hospitalization 5/16/2011 66 Male 201 lb 3/29/2012 Physician Germany
Primary
Concomitant
Aggression Other Serious 5/1/2010 48 Male 181 lb 3/30/2012 Physician Germany
Primary
Secondary
Concomitant
Constipation Other Serious 1/1/2011 56 Male 174 lb 4/3/2012 Physician Germany
Primary
Secondary
Concomitant
Tremor Other Serious 2/8/2010 53 Male 143 lb 4/20/2012 Physician Australia
Primary
Secondary
Concomitant
Urosepsis Hospitalization 3/5/2010 63 Male 181 lb 5/11/2012 Physician Germany
Primary
Secondary
Concomitant
Hepatic Artery Stenosis Hospitalization 3/16/2010 63 Male 181 lb 5/14/2012 Physician Germany
Primary
Secondary
Concomitant
Enterococcal Infection Hospitalization 5/16/2011 66 Male 198 lb 5/22/2012 Physician Germany
Primary
Concomitant
Bone Marrow Disorder Hospitalization 8/1/2008 43 Male 166 lb 5/29/2012 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/27/2012 54 Male 154 lb 6/6/2012 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 5/16/2011 66 Male 198 lb 6/22/2012 Physician Germany
Primary
Concomitant
Oedema Hospitalization 9/3/2008 62 Male 185 lb 6/28/2012 Physician Germany
Primary
Concomitant
Drug Interaction Other Serious 58 Female 7/3/2012 Physician United States
Primary
Concomitant
Interacting
Cardiac Arrest Life Threatening 58 Female 7/4/2012 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 44 Male 143 lb 7/11/2012 United States
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 44 Male 143 lb 7/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 12/1/2011 74 Female 97 lb 8/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 49 Male 1/29/2010 Other Health Professional United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 49 Male 11/9/2010 Other Health Professional United States
Primary
Concomitant
Asthenia Hospitalization 8/1/2008 43 Male 166 lb 8/14/2012 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 8/1/2008 43 Male 166 lb 8/23/2012 Consumer United States
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Increased Death 45 Male 9/11/2012 Other Health Professional Be
Primary
Concomitant
Interacting
Weight Decreased Other Serious 1/2012 74 Female 92 lb 8/29/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Lung Cancer Metastatic Other Serious 4/24/2012 80 Male 10/25/2012 Consumer Es
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 8/16/2012 48 Male 176 lb 11/30/2012 Physician Au
Primary
Concomitant
Rib Fracture Other Serious 7/2012 Female 92 lb 10/4/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Hiccups Other Serious 9/29/2012 55 Male 10/5/2012 Physician In
Primary
Concomitant
Vomiting Life Threatening 10/24/2012 66 Female 175 lb 11/5/2012 Pharmacist Us
Primary
Concomitant

Drug Data