Tacrolimus combined with Voriconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/21/2004 17 Female 73 lb 8/21/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Disorder Hospitalization 4/1/2006 37 Male 110 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Tubular Disorder Hospitalization 4/1/2006 37 Male 110 lb 11/2/2006 Other Health Professional France
Primary
Secondary
Concomitant
Dyspnoea 10/29/2006 Pharmacist United States
Primary
Concomitant
Post Procedural Complication Hospitalization 6/12/2006 69 Male 11/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Other Serious 10/20/2006 9 Male 82 lb 1/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Tuberculosis Hospitalization 2/5/2007 Germany
Primary
Secondary
Disease Progression Other Serious 45 Female 2/27/2007 Japan
Primary
Concomitant
Weight Increased Hospitalization 4/1/2006 37 Male 110 lb 3/2/2007 Other Health Professional
Primary
Secondary
Concomitant
Sepsis Other Serious 10/20/2006 9 Male 82 lb 3/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Weight Increased Hospitalization 4/1/2006 37 Male 110 lb 3/9/2007 Other Health Professional
Primary
Secondary
Concomitant
Systemic Candida Death 45 Female 3/14/2007 Japan
Primary
Concomitant
Septic Shock Death 63 Female 4/9/2007 Physician Spain
Primary
Concomitant
Septic Shock Other Serious 63 Female 4/12/2007 Physician Spain
Primary
Concomitant
Hyperkalaemia Hospitalization 4/6/2007 Female 112 lb 4/27/2007 United States
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 11/1/2005 61 Male 174 lb 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Other Serious 63 Female 154 lb 5/18/2007 Physician Spain
Primary
Concomitant
Paranoia 6/12/2007 62 Female 6/13/2007 United States
Primary
Secondary
Intubation Other Serious 5/31/2007 29 Female 117 lb 8/23/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 107 lb 6/11/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 2/3/2007 39 Male 212 lb 5/2/2007 Pharmacist United States
Primary
Secondary
Mental Status Changes 20 Female 8/15/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 9/11/2007 58 Male 176 lb 9/20/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 98 lb 6/20/2007 United States
Primary
Concomitant
Pleural Effusion Required Intervention 6/25/2007 44 Female 86 lb 7/30/2007 United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2004 Female 10/22/2007 Physician United States
Primary
Secondary
Sepsis Hospitalization 18 Male 10/23/2007
Primary
Secondary
Concomitant
Neuropathy Other Serious 52 Male 11/12/2007 Physician Belgium
Primary
Concomitant
Pneumothorax Death 15 Male 11/14/2007 United Kingdom
Primary
Secondary
Concomitant
Neuropathy Other Serious 52 Male 11/19/2007 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pseudomonas Infection Required Intervention 9/27/2007 39 Male 154 lb 11/1/2007 Pharmacist United States
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 52 Male 1/16/2008
Primary
Secondary
Concomitant
Sepsis Other Serious 10/20/2006 9 Male 82 lb 2/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Peripheral Sensory Neuropathy Other Serious 34 Male 3/3/2008 France
Primary
Concomitant
Neuromyopathy Other Serious 25 Male 3/3/2008 France
Primary
Concomitant
Neuromyopathy Other Serious 24 Male 3/3/2008 France
Primary
Concomitant
Neuromyopathy Other Serious 60 Male 3/3/2008 France
Primary
Concomitant
Neuromyopathy Other Serious 29 Female 3/3/2008 France
Primary
Concomitant
Neuromyopathy Other Serious 17 Male 3/3/2008 France
Primary
Concomitant
Neuromyopathy Other Serious 36 Male 3/3/2008 France
Primary
Concomitant
Neuromyopathy Other Serious 26 Female 3/3/2008 France
Primary
Concomitant
Neuromyopathy Other Serious 43 Female 3/3/2008 France
Primary
Concomitant
Respiratory Failure Other Serious 15 Male 3/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Other Serious 15 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nocardiosis Other Serious Female 3/13/2008 Physician United States
Primary
Concomitant
No Adverse Event 29 Female 4/14/2008 France
Primary
Concomitant
No Adverse Event 25 Male 4/14/2008 France
Primary
Concomitant
No Adverse Event 26 Female 4/16/2008 France
Primary
Concomitant
No Adverse Event 34 Male 4/16/2008 France
Primary
Concomitant
No Adverse Event 24 Male 4/16/2008 France
Primary
Concomitant
Respiratory Failure Hospitalization 11/12/2007 Female 4/17/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/12/2007 Female 4/17/2008 Physician United States
Primary
Secondary
Concomitant
No Adverse Event 43 Female 4/18/2008 France
Primary
Concomitant
No Adverse Event 17 Male 4/18/2008 France
Primary
Concomitant
No Adverse Event 60 Male 4/18/2008 France
Primary
Concomitant
No Adverse Event 36 Male 4/22/2008 France
Primary
Concomitant
Dystonia Other Serious 55 Female 5/19/2008 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 6/13/2008 Physician United States
Primary
Interacting
Zygomycosis Death 62 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Zygomycosis Death 62 Male 6/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/16/2008 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization 49 Male 203 lb 7/18/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 31 Male 7/18/2008
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 15 Male 7/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/18/2008 66 Male 172 lb 8/28/2008 Physician United States
Primary
Secondary
Concomitant
Acanthamoeba Infection Other Serious 53 Male 9/25/2008 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 61 Female 10/6/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/26/2007 Male 185 lb 11/26/2008 Canada
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Haemorrhage Other Serious 61 Male 1/9/2009 Physician United States
Primary
Concomitant
Respiratory Tract Haemorrhage Other Serious 61 Male 2/9/2009 Physician United States
Primary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 24 Male 2/20/2009
Primary
Secondary
Concomitant
Cerebral Aspergillosis Other Serious 42 Male 3/4/2009
Primary
Secondary
Respiratory Failure Other Serious 11/1/2007 3/11/2009 Other Health Professional Canada
Primary
Concomitant
Renal Failure Hospitalization 10/22/2007 58 Male 130 lb 4/1/2009 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/22/2007 58 Male 130 lb 4/6/2009 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/26/2007 58 Male 130 lb 4/7/2009 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/26/2007 4/10/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/10/2008 4/20/2009 Other Health Professional Canada
Primary
Concomitant
Renal Failure Acute Other Serious 11/26/2007 4/20/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2007 41 Female 4/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/23/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/29/2009 Other Health Professional United States
Primary
Concomitant
Graft Versus Host Disease Death 7/5/2008 71 Male 157 lb 5/1/2009 Physician Belgium
Primary
Concomitant
Leukaemia Recurrent Hospitalization 12/26/2006 20 5/12/2009 Physician France
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/26/2007 47 5/14/2009 Physician Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Hospitalization 1/7/2008 55 5/20/2009 Physician Portugal
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 5/25/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Hospitalization 38 Female 5/21/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 43 5/25/2009 Other Health Professional Canada
Primary
Concomitant
Graft Versus Host Disease Hospitalization 1/7/2008 55 5/27/2009 Physician Portugal
Primary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Other Serious 1/29/2009 Male 186 lb 6/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination Life Threatening 3/7/2009 30 Male 174 lb 4/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
Sudden Death Other Serious 7/6/2009 Other Health Professional United States
Primary
Concomitant
Drug Resistance Other Serious 2/27/2009 26 7/15/2009 Physician United Kingdom
Primary
Concomitant
Fungal Infection Death 36 Male 123 lb 7/17/2009 Physician United Kingdom
Primary
Concomitant
Pneumonia Cytomegaloviral Hospitalization 10/22/2006 36 Female 8/25/2009 Physician United States
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 2/4/2009 58 Male 206 lb 8/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 10/28/2009 Physician Korea, Republic Of
Primary
Concomitant
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/13/2009 42 Female 209 lb 10/29/2009 Physician United States
Primary
Concomitant
Periostitis Other Serious 64 Female 11/6/2009 Other Health Professional United States
Primary
Concomitant
Periostitis Other Serious 48 Female 11/6/2009 Other Health Professional United States
Primary
Concomitant
Periostitis Other Serious 38 Male 11/6/2009 Other Health Professional United States
Primary
Concomitant
Periostitis Other Serious 59 Male 11/6/2009 Other Health Professional United States
Primary
Concomitant
Periostitis Hospitalization 67 Female 11/6/2009 Other Health Professional United States
Primary
Concomitant
Death Death Male 141 lb 11/10/2009 Physician Korea, Republic Of
Primary
Concomitant
Myositis Other Serious 34 Female 11/9/2009 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 7 Male 11/17/2009 Consumer United Kingdom
Primary
Secondary
Hepatic Function Abnormal Other Serious 7/12/2009 42 Female 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Other Serious 7/12/2009 42 Female 11/13/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 9/18/2009 56 Male 11/24/2009 United States
Primary
Concomitant
Stenotrophomonas Infection Other Serious 45 Male 11/30/2009
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 5/1/2003 40 Male 12/4/2009 Other Health Professional France
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 1/1/2007 53 Male 12/4/2009 Other Health Professional France
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 1/1/2005 24 Female 12/4/2009 Other Health Professional France
Primary
Concomitant
Syncope Other Serious 9/18/2009 56 Male 12/4/2009 United States
Primary
Concomitant
Stem Cell Transplant Death 9/16/2009 24 Female 126 lb 12/31/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 11/14/2009 56 Female 136 lb 1/21/2010 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/13/2009 42 Female 209 lb 1/28/2010 Physician United States
Primary
Concomitant
Hypersensitivity Hospitalization 1/24/2010 Male 200 lb 2/12/2010 Other Health Professional United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 54 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 28 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 9 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 41 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 28 Male 3/17/2010 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 1/1/2010 9 Male 3/18/2010 Physician United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 1/1/2010 54 Male 3/18/2010 Physician United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 1/1/2010 41 Male 3/18/2010 Physician United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 1/1/2010 28 Male 3/18/2010 Physician United States
Primary
Secondary
Hepatic Function Abnormal Life Threatening 6/28/2009 Male 3/30/2010 Physician Japan
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 9 Male 3/27/2010 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 1/1/2007 53 Male 4/30/2010 Other Health Professional France
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 1/1/2005 24 Female 4/30/2010 Other Health Professional France
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 5/1/2003 40 Male 4/30/2010 Other Health Professional France
Primary
Concomitant
Pneumothorax Other Serious 3/24/2010 56 Male 190 lb 6/4/2010 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 3/23/2010 56 Male 190 lb 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 64 Male 6/8/2010 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 37 Female 6/11/2010 Other Health Professional France
Primary
Secondary
Subcutaneous Nodule Death 54 Female 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data