Fluconazole combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cerebrovascular Accident Hospitalization 11/25/2005 62 Male 1/12/2006 Physician Belgium
Primary
Secondary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 10/18/2004 54 9/16/2005 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 11/25/2005 62 Male 1/23/2006 Physician Belgium
Primary
Secondary
Concomitant
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Required Intervention 12/2/2005 60 Male 161 lb 12/29/2005 United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/18/2006 67 Male 153 lb 4/18/2006 Pharmacist United States
Primary
Secondary
Renal Failure Acute Hospitalization 6/17/2006 44 Female 147 lb 6/30/2006 Other Health Professional United States
Primary
Secondary
Ventricular Tachycardia Life Threatening 8/7/2005 64 Male 7/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 7/13/2006 9 Male 59 lb 7/13/2006 Other Health Professional United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 7/10/2006 26 Female 151 lb 8/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 7/14/2006 18 Female 99 lb 8/9/2006 Pharmacist United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 7/8/2006 68 Female 179 lb 8/9/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 7/11/2006 46 Male 205 lb 8/24/2006 Australia
Primary
Concomitant
Pyrexia Other Serious 9/7/2005 45 Male 205 lb 8/29/2006 Australia
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 7/8/2006 68 Female 179 lb 8/16/2006 Pharmacist United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 7/14/2006 18 Female 99 lb 8/16/2006 Pharmacist United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 7/8/2006 68 Female 179 lb 8/24/2006 Pharmacist United States
Primary
Concomitant
Klebsiella Bacteraemia Other Serious 8/7/2006 Male 10/27/2006 Physician United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 9/7/2005 45 Male 205 lb 10/31/2006 Australia
Primary
Concomitant
Skin Exfoliation Other Serious 31 Female 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Necrosis Other Serious 63 Male 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 34 Female 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Death 65 Male 11/7/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 9/7/2005 45 Male 205 lb 11/16/2006 Australia
Primary
Concomitant
Klebsiella Bacteraemia Other Serious 8/7/2006 Male 35 lb 11/30/2006 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 10/12/2006 46 Male 186 lb 12/7/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 9/7/2005 45 Male 205 lb 1/16/2007 Australia
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/2/2007 52 Female 134 lb 1/17/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/2/2007 52 Female 134 lb 1/24/2007 United States
Primary
Concomitant
Tuberculosis Hospitalization 2/5/2007 Germany
Primary
Secondary
Platelet Count Decreased Other Serious 11/7/2006 62 Male 165 lb 3/9/2007 Physician United States
Primary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/13/2007 Physician Norway
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 11/25/2005 62 Male 4/20/2007 Physician Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 11/7/2006 61 Male 165 lb 4/13/2007 Physician United States
Primary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/30/2007 Physician Norway
Primary
Secondary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Neck Pain Hospitalization 4/17/2007 Male 5/10/2007 Physician United States
Primary
Secondary
Concomitant
Pathogen Resistance Hospitalization 3/29/2007 55 5/15/2007 United Kingdom
Primary
Secondary
Concomitant
Wound Secretion Life Threatening 4/24/2005 44 Female 5/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Life Threatening 5/24/2007 1 Male 21 lb 5/25/2007 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haemorrhage Life Threatening 11/25/2006 33 Female 6/6/2007 Pharmacist United States
Primary
Concomitant
Mucous Membrane Disorder Other Serious 57 Female 6/13/2007 Japan
Primary
Secondary
Concomitant
Liver Transplant Rejection Other Serious 4/16/2007 Male 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Death 63 Male 9/12/2007 Physician United States
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/8/2007 Other Health Professional Malaysia
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/12/2007 Other Health Professional Malaysia
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/1/2003 24 Male 10/16/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2004 Female 10/22/2007 Physician United States
Primary
Secondary
Splenomegaly Hospitalization 3/1/2003 24 Male 10/23/2007
Primary
Secondary
Concomitant
Sepsis Hospitalization 49 Male 11/26/2007
Primary
Secondary
Concomitant
Sepsis Hospitalization 49 Male 12/14/2007 Physician France
Primary
Secondary
Concomitant
Bacterial Infection Other Serious 1 Male 12/23/2007 Physician Poland
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 10/12/2006 Female 143 lb 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 52 Male 1/16/2008
Primary
Secondary
Concomitant
Aspergillosis Death 1 Male 1/24/2008 Physician Poland
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 7/6/2007 Male 2/5/2008 Physician United Kingdom
Primary
Concomitant
Hepatitis C Hospitalization 4/16/2007 Male 2/5/2008 Physician United States
Primary
Concomitant
Immune Reconstitution Syndrome Hospitalization 1/1/2006 49 Male 1/30/2008 Other Health Professional France
Primary
Secondary
Platelet Count Decreased Hospitalization 12/26/2007 48 Female 115 lb 2/12/2008 Pharmacist United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/1/2008 57 Female 2/15/2008 Physician United States
Primary
Concomitant
Splenomegaly Hospitalization 7/6/2007 Male 2/28/2008 Physician United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/12/2008 57 Female 3/11/2008 Physician United States
Primary
Concomitant
Hepatic Artery Stenosis Hospitalization 11/2/2006 60 Female 227 lb 3/13/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 7/21/2006 54 Male 134 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tachypnoea Hospitalization 10/31/2006 59 Female 93 lb 3/27/2008 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 11/7/2006 62 Male 165 lb 3/28/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2005 25 Female 4/8/2008 Physician Austria
Primary
Concomitant
Thrombosis Hospitalization 45 Male 4/3/2008 Physician Singapore
Primary
Secondary
Concomitant
Pyrexia Other Serious 1 Female 4/16/2008 Other Health Professional France
Primary
Secondary
Concomitant
Liver Function Test Abnormal Required Intervention 4/6/2008 65 Male 223 lb 4/14/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 3/1/2008 60 Male 197 lb 4/22/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/13/2008 51 Male 234 lb 4/22/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Required Intervention 4/6/2008 65 Male 223 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 4/6/2008 65 223 lb 4/29/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 3/19/2008 60 Male 197 lb 5/5/2008 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/19/2008 60 Male 197 lb 5/7/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 4/13/2008 51 Male 234 lb 5/8/2008 Physician United States
Primary
Secondary
Concomitant
Transplant Failure Death 6/5/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 5/22/2008 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 3/21/2008 50 Male 234 lb 5/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Disease Other Serious 3/20/2008 60 Male 197 lb 5/15/2008 Physician United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 9 Female 6/13/2008 Germany
Primary
Secondary
Urinary Tract Infection Other Serious 1/1/2007 Female 182 lb 6/17/2008 Physician United States
Primary
Concomitant
Graft Versus Host Disease Hospitalization 5/12/2008 60 Female 234 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Tremor Life Threatening 5/15/2008 Male 207 lb 5/23/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/28/2008 Female 112 lb 5/29/2008 Pharmacist United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 5/12/2008 60 Female 200 lb 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 10/31/2006 59 Female 93 lb 6/20/2008 Physician United States
Primary
Concomitant
Weight Increased Life Threatening 11/4/2007 0 Male 9 lb 6/24/2008 Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9 Female 6/25/2008 Other Health Professional Germany
Primary
Concomitant
Transplant Failure Other Serious 63 Male 7/1/2008 Japan
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 63 Female 7/1/2008 Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 61 Male 7/1/2008 Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 59 Female 7/1/2008 Japan
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 57 Female 7/1/2008 Japan
Primary
Secondary
Concomitant
Tachypnoea Other Serious 10/28/2006 59 Female 93 lb 6/27/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 Female 182 lb 7/10/2008 Physician United States
Primary
Concomitant
Drug Level Increased Other Serious 19 Female 7/11/2008 Other Health Professional United States
Primary
Secondary
Stem Cell Transplant Hospitalization 5/12/2008 60 Female 200 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Eye Disorder Other Serious 34 Male 7/25/2008 Pharmacist United States
Primary
Concomitant
Multi-organ Failure Other Serious 57 Female 8/7/2008 Japan
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 63 Female 8/7/2008 Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 59 Female 8/7/2008 Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 63 Male 8/7/2008 Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 61 Male 8/7/2008 Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 65 Female 8/8/2008 Physician United States
Primary
Secondary
Sinus Bradycardia Hospitalization 65 Female 8/11/2008 Physician United States
Primary
Secondary
Weight Increased Other Serious 5/29/2008 Female 114 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Transplant Rejection Other Serious 33 Male 8/6/2008 Physician Italy
Primary
Secondary
Venoocclusive Liver Disease Other Serious 8/15/2008 Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 33 Male 8/13/2008 Italy
Primary
Secondary
Concomitant
Neck Pain Hospitalization 4/17/2007 Male 8/28/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 33 Male 9/4/2008 Consumer Italy
Primary
Secondary
Renal Failure Hospitalization 33 Male 9/5/2008 Italy
Primary
Secondary
Neck Pain Hospitalization 4/17/2007 Male 9/16/2008 Physician United States
Primary
Secondary
Concomitant
Neck Pain Hospitalization 4/17/2007 Male 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization Female 9/12/2008 Other Health Professional
Primary
Concomitant
Weight Increased Other Serious 5/29/2008 Female 114 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Sinus Bradycardia Other Serious 65 Female 10/16/2008 Physician United States
Primary
Secondary
Concomitant
Transplant Rejection Death 10/4/2007 Female 169 lb 10/8/2008 United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 10/8/2008 69 Male 229 lb 10/23/2008 Pharmacist United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 44 Male 11/3/2008 Physician Italy
Primary
Secondary
Concomitant
Viral Infection Other Serious 50 Male 11/3/2008 Physician Italy
Primary
Secondary
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Stomatitis Hospitalization 10/26/2007 10 Male 12/8/2008 Physician Japan
Primary
Secondary
Sputum Culture Positive Other Serious 58 Male 12/12/2008 Other Health Professional Turkey
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 57 Female 79 lb 12/12/2008 Physician China
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/16/2008 Male 12/30/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 5/1/2008 68 Female 122 lb 12/26/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/3/2009 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/5/2009 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/20/2009 42 Male 287 lb 3/23/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/23/2009 Female 25 lb 3/25/2009 United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 7/5/2008 71 Male 157 lb 5/1/2009 Physician Belgium
Primary
Concomitant
Respiratory Arrest Death 63 Male 5/1/2009 Physician China
Primary
Concomitant
Septic Shock Other Serious 11/30/2007 50 Female 119 lb 5/22/2009 Physician Belgium
Primary
Concomitant
Retinopathy Disability 5/4/2009 Male 5/27/2009 Physician United Kingdom
Primary
Concomitant
Transplant Rejection Other Serious 41 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Sickness Other Serious 4/30/2007 24 Female 194 lb 5/28/2009 Physician United States
Primary
Concomitant
Sepsis Disability 5/4/2009 Male 6/11/2009 Physician United Kingdom
Primary
Concomitant
Viral Infection Other Serious 41 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Interacting
Bone Marrow Failure Hospitalization 8/11/2003 Male 146 lb 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Wound Infection Hospitalization 4/2/2004 Female 220 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Lymphocele Hospitalization 6/17/2004 Male 159 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant

Drug Data