Cyclophosphamide combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transplant Rejection Hospitalization 58 Female 12/29/2005 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Required Intervention 10/1/2005 58 Female 1/16/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 12/16/2005 Male 160 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 6/7/2006 Male 135 lb 6/8/2006 United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 2 Male 6/29/2006 United States
Primary
Concomitant
Troponin I Increased Hospitalization 8/1/2006 Male 181 lb 8/1/2006 United States
Primary
Secondary
Hospitalisation Other Serious 1/19/2006 Female 179 lb 10/30/2006 Other Health Professional United States
Primary
Concomitant
Skin Exfoliation Other Serious 31 Female 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Mechanical Ileus Other Serious 11 Male 12/8/2006 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Mechanical Ileus Other Serious 11 Male 12/20/2006 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 1/30/2007 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Viral Myocarditis Other Serious 56 Male 2/22/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 56 Male 2/26/2007
Primary
Secondary
Chronic Graft Versus Host Disease Other Serious 48 Male 3/3/2007 Japan
Primary
Concomitant
Weight Decreased Other Serious 48 Male 3/10/2007 Japan
Primary
Secondary
Concomitant
Ureteric Stenosis Other Serious 35 Male 3/14/2007 Japan
Primary
Secondary
Concomitant
Vomiting Disability 1/30/2007 7 Female 3/13/2007 Japan
Primary
Concomitant
Ureteric Stenosis Other Serious 35 Male 3/28/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 52 Male 4/4/2007 Other Health Professional United States
Primary
Secondary
Staphylococcal Sepsis Other Serious 31 Male 4/4/2007 Other Health Professional United States
Primary
Secondary
Varicella Hospitalization 12/20/2006 52 Male 4/19/2007 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2006 54 Female 4/19/2007 Japan
Primary
Secondary
Concomitant
Vomiting Death 12/20/2006 52 Male 5/7/2007 Japan
Primary
Secondary
Concomitant
Weight Increased Death 2/14/2007 39 Female 5/17/2007 Japan
Primary
Secondary
Concomitant
Sinusitis Fungal Hospitalization 62 Male 6/11/2007 Japan
Primary
Secondary
Concomitant
Sinusitis Fungal Hospitalization 62 Male 6/11/2007 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2006 54 Female 6/11/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 6/22/2007 Japan
Primary
Secondary
Concomitant
Vomiting Death 12/20/2006 52 Male 6/20/2007 Japan
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 6/22/2007 Japan
Primary
Secondary
Concomitant
Mechanical Ileus Life Threatening 8/30/2006 11 Male 7/3/2007 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/30/2006 11 Male 7/5/2007 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 2/10/2001 12 Male 7/5/2007 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 2/10/2001 12 Male 7/5/2007 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/30/2007 7 Female 8/16/2007 Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 3/21/2007 20 Male 9/18/2007 Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 14 Male 9/19/2007 Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 12/18/2006 50 Male 9/20/2007 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Liver Disease 7/30/2007 51 Male 10/26/2007 Japan
Primary
Concomitant
Somnolence Other Serious 52 Male 10/31/2007 Physician Japan
Primary
Secondary
Concomitant
Cerebral Toxoplasmosis Other Serious 52 Male 11/16/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2007 4 Male 11/16/2007 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/19/2007 18 Female 11/16/2007 Japan
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 65 Female 11/26/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Virus Serology Test Positive Other Serious 56 Male 11/20/2007 Japan
Primary
Secondary
Stem Cell Transplant Other Serious 1/1/2005 65 Female 11/20/2007 Consumer United States
Primary
Secondary
Oral Herpes Other Serious 1/1/2005 65 Female 11/29/2007 Consumer
Primary
Secondary
Thrombotic Microangiopathy Other Serious 23 Female 12/6/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 48 Male 12/6/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 46 Male 12/6/2007 Other Health Professional Japan
Primary
Secondary
Rhinorrhoea Other Serious 55 Male 12/6/2007 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 48 Male 12/13/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 46 Male 12/14/2007 Other Health Professional Japan
Primary
Secondary
Rhinorrhoea Other Serious 55 Male 12/14/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Dysfunction Life Threatening 11/3/2007 16 Female 208 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 3/21/2007 20 Male 1/3/2008 Japan
Primary
Concomitant
Thrombotic Microangiopathy Death 23 Female 1/14/2008
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 48 Male 1/14/2008
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 46 Male 1/14/2008
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/28/2007 Female 197 lb 1/8/2008 United States
Primary
Secondary
Nuclear Magnetic Resonance Imaging Brain Abnormal Death 11 Female 1/22/2008 Other Health Professional Saudi Arabia
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 1/1/2005 65 Female 1/15/2008 Consumer United States
Primary
Secondary
Sepsis Hospitalization 2/3/2008 Male 167 lb 2/6/2008 United States
Primary
Secondary
Serositis Death 1 3/6/2008 Consumer Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 3/7/2008 Consumer United Kingdom
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 11 3/11/2008 Consumer Japan
Primary
Concomitant
Venoocclusive Disease Other Serious 13 3/11/2008 Consumer Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 14 3/11/2008 Consumer Japan
Primary
Concomitant
Cytomegalovirus Enteritis Other Serious 12 3/11/2008 Consumer Japan
Primary
Concomitant
Stem Cell Transplant Other Serious 15 Unknown 3/13/2008 Japan
Primary
Concomitant
Stem Cell Transplant Death 1 3/13/2008 Japan
Primary
Concomitant
Serositis Death 1 3/24/2008 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 15 3/24/2008 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 11 3/24/2008 Physician Japan
Primary
Concomitant
Venoocclusive Disease Other Serious 13 3/24/2008 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 14 3/24/2008 Physician Japan
Primary
Concomitant
Cytomegalovirus Enteritis Other Serious 12 3/24/2008 Physician Japan
Primary
Concomitant
Venoocclusive Disease Hospitalization 2/12/2008 Male 231 lb 3/17/2008 United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 12 Male 3/27/2008 Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/27/2008 Other Health Professional Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/31/2008 Other Health Professional Germany
Primary
Secondary
Therapeutic Agent Toxicity Death 4/2/2008 Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death Male 4/2/2008 Germany
Primary
Secondary
Vertigo Death 58 Male 3/29/2008 Physician Germany
Primary
Secondary
Venoocclusive Liver Disease Other Serious 4/7/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12 Male 4/7/2008 Japan
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/3/2007 16 Female 208 lb 4/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 66 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 2/12/2008 Male 231 lb 4/16/2008 United States
Primary
Secondary
Stomatitis Life Threatening 10/31/2007 50 Male 4/30/2008 Japan
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 2/6/2007 23 Male 4/30/2008 Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious Male 5/13/2008 Other Health Professional United States
Primary
Secondary
Pyrexia Other Serious 5 Female 5/13/2008
Primary
Secondary
Concomitant
Vertigo Death Male 5/2/2008 Germany
Primary
Concomitant
Serositis Hospitalization 12/15/2007 Female 104 lb 5/2/2008 United States
Primary
Secondary
Concomitant
Serositis Hospitalization 12/15/2007 Female 104 lb 5/9/2008 United States
Primary
Secondary
Concomitant
Transplant Failure Death 6/5/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 49 Male 5/19/2008 Other Health Professional United States
Primary
Secondary
Sepsis Life Threatening 10/8/2007 57 Female 5/15/2008 Other Health Professional Japan
Primary
Concomitant
Pneumonia Aspiration Hospitalization 12/20/2007 1 Male 5/15/2008 Physician Japan
Primary
Concomitant
Tumour Flare Life Threatening 10/30/2007 34 Male 5/15/2008 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 12/13/2006 30 Male 5/15/2008 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/6/2007 55 Female 5/15/2008 Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 23 Male 5/20/2008 Other Health Professional United States
Primary
Secondary
Vulval Cancer Other Serious 5/20/2008 United States
Primary
Secondary
Concomitant
Vulval Cancer Other Serious 5/22/2008 United States
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 20 Female 6/4/2008 Other Health Professional United States
Primary
Secondary
Sepsis Death 62 Male 6/5/2008 Other Health Professional Austria
Primary
Secondary
Intestinal Obstruction Other Serious 20 Female 6/9/2008 Other Health Professional United States
Primary
Secondary
Sepsis Death 62 Male 6/10/2008 Other Health Professional Austria
Primary
Secondary
Vomiting Life Threatening 10/21/2007 42 Male 6/6/2008 Japan
Primary
Concomitant
Respiratory Failure Other Serious 64 Female 6/13/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 20 Female 6/6/2008 United States
Primary
Secondary
Concomitant
Zygomycosis Death 62 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 12/13/2006 30 Male 6/11/2008 Japan
Primary
Secondary
Concomitant
Zygomycosis Death 62 Male 6/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Life Threatening 1/22/2008 26 Female 6/27/2008 Other Health Professional Japan
Primary
Concomitant
Oral Disorder Death 45 Female 6/27/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 23 Male 7/3/2008
Primary
Secondary
Concomitant
Stomatitis Life Threatening 10/23/2007 50 Male 7/1/2008 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 2/29/2008 1 Female 7/2/2008 Japan
Primary
Concomitant
Stomatitis Hospitalization 8/31/2007 60 Male 7/10/2008 Japan
Primary
Concomitant
Stomatitis 2/3/2008 3 Female 7/16/2008 Japan
Primary
Concomitant
Stomatitis Life Threatening 11/30/2007 50 Male 7/16/2008 Japan
Primary
Concomitant
Hypertrophic Cardiomyopathy 5/15/2008 1 Male 7/17/2008 Other Health Professional Japan
Primary
Concomitant
Nausea Death 6/27/2007 47 Female 7/17/2008 Other Health Professional Japan
Primary
Concomitant
Leukaemia Other Serious 39 Female 8/5/2008 United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 39 Female 8/5/2008 Other Health Professional United States
Primary
Secondary
Therapeutic Agent Toxicity Death 8/7/2008 Germany
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 8/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Bone Pain Other Serious 8/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 8/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Death 39 Female 8/9/2008 United States
Primary
Secondary
Weight Increased Other Serious 5/29/2008 Female 114 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting 11/30/2007 9 Male 8/14/2008 Other Health Professional Japan
Primary
Concomitant
Stomatitis 5/23/2007 29 Female 8/14/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 4/17/2007 40 Female 8/14/2008 Other Health Professional Japan
Primary
Concomitant
Stem Cell Transplant Disability 39 Female 8/20/2008 Physician United States
Primary
Secondary
Stomatitis Hospitalization 5/27/2007 53 Female 8/22/2008 Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 3/14/2007 35 Female 9/10/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 12/16/2006 50 Male 9/9/2008 Japan
Primary
Concomitant

Drug Data