Neoral combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Visual Field Defect Hospitalization 12/8/2005 Female 1/3/2006 Physician Japan
Primary
Concomitant
Myocarditis Life Threatening 8/12/2006 58 Male 123 lb 8/23/2006 Physician Brazil
Primary
Secondary
White Blood Cell Count Increased Hospitalization 4/28/2006 Male 123 lb 9/8/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/18/2002 41 Male 10/5/2006 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/12/2006 33 Male 10/5/2006 Japan
Primary
Secondary
Concomitant
Myocarditis Life Threatening 8/12/2006 58 Male 123 lb 10/11/2006 Physician Brazil
Primary
Secondary
White Blood Cell Count Increased Hospitalization 1/18/2002 41 Male 10/12/2006 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/12/2006 33 Male 10/12/2006 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/12/2006 33 Male 10/12/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/18/2002 41 Male 10/12/2006 Japan
Primary
Secondary
Concomitant
Myasthenia Gravis Hospitalization 80 11/28/2006 Physician Japan
Primary
Concomitant
Sinusitis Fungal Hospitalization 62 Male 6/11/2007 Japan
Primary
Secondary
Concomitant
Sinusitis Fungal Hospitalization 62 Male 6/11/2007 Japan
Primary
Secondary
Concomitant
Urine Analysis Abnormal Hospitalization 3/2/2004 38 Male 158 lb 6/15/2007 Physician United Kingdom
Primary
Secondary
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 6/22/2007 Japan
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 6/22/2007 Japan
Primary
Secondary
Concomitant
Endocarditis Hospitalization 10/27/2005 68 Female 1/15/2007 Physician France
Primary
Concomitant
Renal Impairment Hospitalization 4/1/1998 26 Male 146 lb 10/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Microangiopathic Haemolytic Anaemia Hospitalization 5/2/1998 26 Male 11/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/1/2001 52 Male 12/21/2007 Japan
Primary
Concomitant
Liver Transplant Rejection Other Serious 6/22/2004 58 Female 108 lb 2/6/2008 Japan
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 2/12/2008 69 Female 117 lb 2/26/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 2/12/2008 69 Female 117 lb 2/29/2008 Japan
Primary
Secondary
Concomitant
Tremor Life Threatening 1/20/2008 75 Male 4/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/7/2005 8 Male 7/9/2008 Japan
Primary
Secondary
Concomitant
Pneumomediastinum Other Serious 6/1/2007 Male 7/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumomediastinum Other Serious 6/1/2007 Male 7/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/7/2005 8 Male 7/30/2008 Japan
Primary
Secondary
Concomitant
Pneumomediastinum Other Serious 6/1/2007 Male 7/31/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumomediastinum Other Serious 6/1/2007 Male 8/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Cyst Other Serious 3/1/2008 36 Male 9/19/2008 Other Health Professional Japan
Primary
Secondary
Tachycardia Hospitalization 7/25/2008 Male 126 lb 10/16/2008 Physician Australia
Primary
Secondary
Concomitant
Myopathy Hospitalization 8/15/2000 Female 140 lb 10/23/2008 Physician Spain
Primary
Secondary
Concomitant
Tachycardia Other Serious 7/25/2008 Male 126 lb 10/28/2008 Physician Australia
Primary
Secondary
Concomitant
Pyrexia Life Threatening 10/13/2008 Female 12/5/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/18/2007 27 Female 12/17/2008 Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 10/13/2008 Female 12/19/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Tremor Other Serious 10/28/2008 64 Female 1/27/2009 Other Health Professional France
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/7/2005 8 Male 1/29/2009 Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/1/2008 6 Male 2/9/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Sclerema Other Serious 10/1/2004 2/18/2009 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 6/1/2008 Male 192 lb 3/11/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Tract Haemorrhage Other Serious 9/2/2006 18 Male 3/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyelonephritis Disability 2/19/2008 39 Female 134 lb 5/12/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2008 Female 6/30/2009 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Other Serious 55 Female 7/21/2009 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Other Serious 55 Female 7/21/2009 Physician Japan
Primary
Secondary
Concomitant
Postictal State Other Serious 4/13/2009 54 Male 215 lb 7/24/2009 Consumer United States
Primary
Concomitant
Tumour Excision Other Serious 1/1/2006 38 Female 8/7/2009 Other Health Professional France
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 57 Female 9/4/2009 Other Health Professional Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 6/1/2008 Male 192 lb 10/11/2009 Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 55 Male 10/12/2009 Physician Belgium
Primary
Secondary
Cholelithiasis Hospitalization 12/25/2007 30 Male 145 lb 10/12/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2007 49 Female 99 lb 10/6/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2008 Female 10/23/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2008 Female 10/27/2009 Physician Japan
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 1/8/2009 62 Female 117 lb 11/13/2009 Physician Japan
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 1/8/2009 62 117 lb 12/2/2009 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 1/8/2009 62 Female 117 lb 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2008 Female 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Hospitalization 4/1/2008 Female 141 lb 3/11/2010 Physician Germany
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 12/15/2008 49 Female 4/12/2010 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 12/15/2008 49 Female 4/12/2010 Other Health Professional Japan
Primary
Concomitant
Peritoneal Disorder Hospitalization 4/29/2009 53 Male 163 lb 4/28/2010 Physician France
Primary
Concomitant
Tremor Other Serious 9/1/2007 49 Female 99 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Ureteritis Other Serious 10/5/2005 48 Male 4/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 3/5/2008 46 Female 5/10/2010 Physician Germany
Primary
Secondary
Concomitant
Ureteritis Other Serious 10/5/2005 48 Male 5/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/13/2008 24 Female 5/27/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 5/1/2007 45 Female 6/11/2010 Physician Germany
Primary
Secondary
Concomitant
Pyelonephritis Disability 2/19/2008 39 Female 134 lb 6/24/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/10/2010 67 Male 155 lb 6/25/2010 United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 4/10/2010 67 Male 155 lb 7/8/2010 United Kingdom
Primary
Concomitant
Transaminases Increased Other Serious 5/1/2007 45 Female 7/16/2010 Physician Germany
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/3/2008 45 Male 220 lb 9/3/2010 Physician Netherlands
Primary
Secondary
Concomitant
Skin Disorder Other Serious 1/1/2007 55 Male 9/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Disorder 4/5/2007 55 Male 10/7/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 6/24/2010 27 Female 127 lb 10/13/2010 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 5/1/2010 48 Male 181 lb 11/2/2010 Physician Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 37 Female 11/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 2/1/2006 3 Female 29 lb 11/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/1/2010 48 Male 181 lb 11/19/2010 Physician Germany
Primary
Secondary
Concomitant
Tendonitis Other Serious 4/5/2007 55 Male 12/10/2010 Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2006 52 Male 119 lb 12/17/2010 Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/2/2010 56 Female 132 lb 12/21/2010 Physician Brazil
Primary
Secondary
Urinary Tract Infection Hospitalization 12/2/2010 56 Female 132 lb 1/20/2011 Physician Brazil
Primary
Secondary
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 12/15/2008 49 Female 2/10/2011 Other Health Professional Japan
Primary
Concomitant
Alopecia Other Serious 2/1/2010 45 Female 2/18/2011 Other Health Professional Canada
Primary
Secondary
Blood Creatinine Increased Other Serious 12/15/2008 49 Female 161 lb 2/23/2011 Other Health Professional Japan
Primary
Concomitant
Liver Disorder Hospitalization 5/20/2008 49 Female 3/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 8/10/2009 13 Female 87 lb 2/23/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Decreased Hospitalization 12/1/2006 52 Male 119 lb 3/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 5/1/2004 51 Male 3/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Other Serious 8/10/2009 13 Female 87 lb 3/11/2011 Physician Japan
Primary
Concomitant
Hypertriglyceridaemia Other Serious 50 Male 3/29/2011 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 2/1/2006 3 Female 29 lb 5/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Transplant Rejection Death 4/12/2001 1 Male 17 lb 6/16/2011 Physician Japan
Primary
Concomitant
Dysplasia Hospitalization Female 130 lb 6/21/2011 United States
Primary
Concomitant
Thrombosis Hospitalization 8/24/2009 43 Female 165 lb 6/21/2011 Consumer United States
Primary
Concomitant
Hepatitis C Hospitalization 55 Female 7/13/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 55 Female 7/19/2011 Japan
Primary
Secondary
Concomitant
Bile Duct Stone Hospitalization 12/18/2010 56 Female 7/19/2011 Consumer United States
Primary
Concomitant
Speech Disorder Hospitalization 61 Male 7/21/2011 United States
Primary
Concomitant
Haematoma Hospitalization 6/4/2004 54 Female 7/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Ischaemia Other Serious 4/5/2011 64 Female 7/26/2011 Other Health Professional Switzerland
Primary
Concomitant
Ovarian Neoplasm Other Serious 2/1/2010 45 Female 7/29/2011 Other Health Professional Canada
Primary
Secondary
Ovarian Neoplasm Other Serious 2/1/2010 45 Female 8/2/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Necrosis Other Serious 64 Female 8/3/2011 Other Health Professional Switzerland
Primary
Concomitant
Renal Infarct Other Serious 64 Female 8/11/2011 Other Health Professional Switzerland
Primary
Concomitant
Blindness Unilateral Hospitalization 61 Male 8/16/2011 United States
Primary
Concomitant
Speech Disorder Hospitalization 12/2/2010 61 Male 123 lb 8/16/2011 Consumer United States
Primary
Concomitant
Acne Other Serious 2/1/2010 45 Female 8/22/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Ischaemia Other Serious 64 Female 9/13/2011 Other Health Professional Switzerland
Primary
Concomitant
Device Occlusion Hospitalization 4/15/2008 50 Male 10/21/2011 Physician Germany
Primary
Secondary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 12/15/2004 31 Female 11/14/2011 Japan
Primary
Secondary
Concomitant
Glucose Tolerance Impaired Hospitalization Male 95 lb 11/21/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 10/3/2011 65 Female 11/29/2011 Physician United States
Primary
Secondary
Fluid Retention Other Serious 10/3/2011 65 Female 11/29/2011 Physician United States
Primary
Secondary
Diarrhoea Other Serious 40 Female 12/6/2011 Other Health Professional Japan
Primary
Secondary
Pathological Fracture Hospitalization 11/25/2011 64 Male 12/14/2011 Other Health Professional Sweden
Primary
Concomitant
Abdominal Pain Hospitalization 1/6/2003 3 Female 12/19/2011 Japan
Primary
Secondary
Concomitant
Arrhythmia Death 12/7/2011 16 Male 88 lb 12/20/2011 Pharmacist Japan
Primary
Concomitant
Herpes Zoster Other Serious 48 Male 12/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 6/13/2009 74 Female 1/3/2012 Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 6/12/2009 56 Male 110 lb 1/18/2012 Physician Japan
Primary
Concomitant
Oedema Other Serious Male 154 lb 2/13/2012 Pharmacist Ireland
Primary
Secondary
Concomitant
Cerebral Infarction Death 6/12/2009 56 Male 110 lb 2/22/2012 Physician Japan
Primary
Concomitant
Pharyngeal Oedema Other Serious 10/3/2011 65 Female 2/28/2012 Physician United States
Primary
Secondary
Anuria Other Serious 10/3/2011 65 Female 2/28/2012 Consumer United States
Primary
Secondary
Respiratory Failure Death 7/21/2004 55 Female 3/2/2012 Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Recurrent Death 9/21/2005 59 Male 3/5/2012 Japan
Primary
Secondary
Concomitant
Sinusitis Hospitalization 1/6/2003 3 Female 3/6/2012 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/21/2009 58 Male 216 lb 1/6/2012 Other Health Professional United States
Primary
Concomitant
Diverticulitis Hospitalization 8/20/2007 38 Male 1/6/2012 Consumer United States
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 8/22/2006 12 Female 1/6/2012 Consumer United States
Primary
Concomitant
Speech Disorder Hospitalization 12/2/2010 61 Male 123 lb 1/6/2012 Other Health Professional United States
Primary
Concomitant
Speech Disorder Hospitalization 12/2/2010 61 Male 123 lb 1/6/2012 Other Health Professional United States
Primary
Concomitant
Behcet's Syndrome Hospitalization 7/1/2011 6 Male 42 lb 3/30/2012 Japan
Primary
Concomitant
Dehydration Life Threatening Male 154 lb 4/2/2012 Pharmacist Ireland
Primary
Secondary
Concomitant
Behcet's Syndrome Hospitalization 7/1/2011 6 Male 42 lb 4/6/2012 Japan
Primary
Concomitant
Rash Other Serious 8/10/2009 13 Female 87 lb 4/6/2012 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 4/1/2010 47 Female 130 lb 4/13/2012 Lawyer United States
Primary
Concomitant
Pneumonia Death 4/20/2012 Other Health Professional China
Primary
Secondary
Concomitant
Post Transplant Distal Limb Syndrome Hospitalization 37 Male 4/25/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 37 Male 4/25/2012 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data