Folic Acid combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/20/2005 Female 9/22/2005 United States
Primary
Concomitant
Urticaria 9/14/2005 78 Male 240 lb United States
Primary
Concomitant
Nephropathy Toxic Required Intervention 7/28/2005 66 Male 157 lb 10/25/2005 Pharmacist United States
Primary
Concomitant
Pleurisy Hospitalization 8/7/2005 71 Male 2/6/2006 Physician Japan
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/1/2006 28 Female 112 lb 3/28/2006 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 1/1/2006 Male 5 lb 3/28/2006 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 5/1/2006 11 Male 5/16/2006 Canada
Primary
Concomitant
Ventricular Tachycardia Life Threatening 8/7/2005 64 Male 7/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 1/16/2006 57 Male 206 lb 5/4/2006 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 4/20/2006 Male 219 lb 4/21/2006 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased Hospitalization 4/13/2006 53 Male 167 lb 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/12/2006 58 Female 205 lb 11/20/2006 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 10/12/2006 46 Male 186 lb 12/7/2006 Pharmacist United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Disability 7/24/2006 43 Male 148 lb 12/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wound Debridement Required Intervention 4/18/2006 54 Male 174 lb 8/8/2006 Pharmacist United States
Primary
Concomitant
Stent Occlusion Other Serious 10/7/2004 Male 127 lb 3/22/2007 Physician United Kingdom
Primary
Concomitant
Stress Other Serious 12/21/2006 80 Female 81 lb 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/13/2006 59 Male 4/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious Male 4/27/2007 Pharmacist United Kingdom
Primary
Concomitant
Peritonitis Sclerosing Hospitalization 3/13/2006 59 Male 5/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 5/31/2007 51 Female 155 lb 6/25/2007 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased 1/1/2006 Female 7/25/2007 Other Health Professional United States
Primary
Concomitant
Septic Shock Life Threatening 2/20/2007 Female 8/17/2007 Other Health Professional France
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/22/2006 Male 173 lb 12/26/2006 Pharmacist United States
Primary
Concomitant
Colitis Ulcerative Hospitalization 1/7/2007 21 Male 114 lb 2/1/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/20/2006 68 Female 154 lb 9/13/2007 Pharmacist United States
Primary
Concomitant
Stem Cell Transplant Hospitalization 7/28/2007 Male 9/20/2007 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 Male 9/28/2007 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 5/29/2007 Female 110 lb 10/17/2007 United Kingdom
Primary
Concomitant
Myositis Hospitalization 3/22/2007 59 Female 144 lb 11/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Microangiopathic Haemolytic Anaemia Hospitalization 5/2/1998 26 Male 11/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/23/2007 Female 86 lb 12/11/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/23/2007 57 Female 110 lb 12/31/2007 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/19/2007 Female 86 lb 1/2/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/15/2008 53 Female 126 lb 1/24/2008 Physician United States
Primary
Secondary
Concomitant
Death Other Serious Female 90 lb 2/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 1/1/2008 Female 2/22/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious Female 90 lb 2/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Complications Of Transplanted Liver Death 10/26/2007 Female 2/26/2008 Physician United States
Primary
Secondary
Concomitant
Viral Diarrhoea Hospitalization 2/4/2008 56 Female 2/29/2008 Physician Sweden
Primary
Concomitant
Tinnitus Hospitalization 47 Female 3/7/2008 Pharmacist United States
Primary
Concomitant
Transplant Rejection Hospitalization 1/17/2003 68 Male 3/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/12/2007 Female 4/17/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/12/2007 Female 4/17/2008 Physician United States
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 10/7/2004 69 Male 4/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Death 1/4/2007 Male 216 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 4/25/2008 60 Male 5/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 3/25/2008 60 Male 6/3/2008 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 42 Female 130 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Life Threatening 5/29/2008 39 Male 143 lb 8/8/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Ventricular Hypoplasia Congenital Anomaly 1/1/2008 Female 8/27/2008 Other Health Professional United States
Primary
Secondary
Rib Deformity Congenital Anomaly Female 8/28/2008
Primary
Secondary
Supraventricular Extrasystoles Hospitalization 8/16/2008 68 Male 8/27/2008 Physician United States
Primary
Concomitant
Rib Deformity Congenital Anomaly Female 9/26/2008
Primary
Secondary
Supraventricular Extrasystoles Hospitalization 8/16/2008 68 Male 9/24/2008 Physician United States
Primary
Concomitant
Shock Life Threatening 5/29/2008 39 Male 143 lb 9/25/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Pleural Effusion Hospitalization 8/16/2008 68 Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Hypoplasia Congenital Anomaly Female 11/5/2008
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 7/31/2008 Female 103 lb 11/5/2008 Pharmacist United States
Primary
Concomitant
Respiratory Rate Decreased Required Intervention 7/16/2008 72 Male 159 lb 8/1/2008 Pharmacist United States
Primary
Secondary
Concomitant
Myositis Hospitalization 7/15/2008 59 Male 11/25/2008 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 1/1/2007 Male 110 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Myositis Hospitalization 7/15/2008 59 Male 2/13/2009 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 9/1/2007 Female 90 lb 2/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Microtia Congenital Anomaly 3/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Life Threatening 9/1/2007 73 Female 90 lb 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myositis Hospitalization 7/15/2008 59 Male 3/11/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 9/1/2007 Female 88 lb 3/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 9/1/2007 73 Female 90 lb 3/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 9/1/2007 73 Female 90 lb 3/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/1/2006 40 Male 4/3/2009 United States
Primary
Concomitant
Rheumatoid Arthritis Life Threatening 9/1/2007 73 Female 90 lb 3/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/25/2004 Female 126 lb 4/3/2009 Physician Brazil
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/10/2008 4/20/2009 Other Health Professional Canada
Primary
Concomitant
Viral Infection Other Serious 3/27/2007 Female 99 lb 4/27/2009 Physician Canada
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 2/1/2008 59 Female 6/12/2009 Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 8/5/2003 Male 141 lb 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Ureteric Stenosis Hospitalization 11/29/2004 Male 187 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 59 Female 6/26/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 59 Female 6/26/2009
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 4/2/2009 39 Female 110 lb 4/28/2009 Pharmacist United States
Primary
Concomitant
Hypertrichosis Other Serious 4/23/2004 Female 7/1/2009 Physician Spain
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 59 Female 7/6/2009 Other Health Professional Canada
Primary
Concomitant
Interacting
Rheumatoid Nodule Hospitalization 10/17/2007 58 Male 154 lb 7/1/2009 Physician Japan
Primary
Secondary
Concomitant
Ventricular Hypoplasia Death Female 9/9/2009 Physician United States
Primary
Secondary
Ventricular Hypoplasia Death Female 9/9/2009 Physician United States
Primary
Secondary
Ventricular Hypoplasia Hospitalization Female 9/21/2009
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/17/2009 41 Male 158 lb 9/14/2009 Physician United States
Primary
Concomitant
Ventricular Hypoplasia Death 1/1/2008 Female 10/2/2009 Other Health Professional United States
Primary
Secondary
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Hospitalization 10/5/2009 46 Male 10/30/2009 Physician United States
Primary
Concomitant
Product Quality Issue Other Serious 8/26/2009 53 Male 128 lb 10/2/2009 United States
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 10/5/2009 46 Male 11/12/2009 Physician United States
Primary
Concomitant
Viral Haemorrhagic Cystitis Hospitalization 8/17/2009 41 Male 158 lb 11/9/2009 Physician United States
Primary
Concomitant
Syncope Other Serious 9/18/2009 56 Male 11/24/2009 United States
Primary
Concomitant
Viral Haemorrhagic Cystitis Hospitalization 8/17/2009 41 Male 158 lb 11/10/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Syncope Other Serious 9/18/2009 56 Male 12/4/2009 United States
Primary
Concomitant
Herpes Zoster Hospitalization 5/6/2008 Male 110 lb 12/30/2009 Japan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 1/1/2009 41 Male 158 lb 12/16/2009 Physician United States
Primary
Concomitant
Viral Haemorrhagic Cystitis Required Intervention 6/8/2009 41 Male 158 lb 1/4/2010 Physician United States
Primary
Concomitant
Palpitations Other Serious 12/26/2009 56 Male 1/21/2010 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 59 Female 1/22/2010 Other Health Professional Thailand
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 6/18/2009 57 Male 1/12/2010 Other Health Professional France
Primary
Concomitant
Pain Other Serious 1/6/2010 Female 115 lb 1/28/2010 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/22/2009 Female 2/1/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 6/18/2009 57 Male 2/3/2010 Physician France
Primary
Concomitant
Pain Other Serious 1/6/2010 Female 115 lb 2/26/2010 Japan
Primary
Secondary
Concomitant
Shock Other Serious 1/6/2010 Female 115 lb 3/26/2010 Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/18/2009 57 Male 3/29/2010 Other Health Professional France
Primary
Concomitant
Vomiting Required Intervention 6/8/2009 41 Male 158 lb 3/31/2010 Physician United States
Primary
Concomitant
Suffocation Feeling Hospitalization 10/29/2009 45 Female 4/21/2010 Japan
Primary
Concomitant
Drug Interaction Other Serious Male 5/4/2010 Pharmacist France
Primary
Concomitant
Interacting
Drug Interaction Other Serious Male 5/6/2010 Physician France
Primary
Concomitant
Interacting
Vomiting Other Serious 9/1/2009 20 Female 5/20/2010 United States
Primary
Concomitant
Hypotension Death Female 5/21/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 12/18/2009 68 Female 5/19/2010 Japan
Primary
Secondary
Concomitant
Intestinal Fistula Hospitalization 5/12/2010 13 Male 82 lb 5/28/2010 Physician United States
Primary
Concomitant
Stem Cell Transplant Hospitalization 5/12/2010 64 Male 5/25/2010 Other Health Professional Canada
Primary
Concomitant
Suffocation Feeling Hospitalization 10/29/2009 45 Female 6/3/2010 Physician Japan
Primary
Concomitant
Shock Other Serious 1/6/2010 67 Female 115 lb 6/17/2010 Physician Japan
Primary
Secondary
Concomitant
Suffocation Feeling Hospitalization 10/29/2009 45 Female 6/21/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 7/1/2010 United States
Primary
Concomitant
Transplant Rejection Hospitalization 6/21/2010 51 Male 7/6/2010 Other Health Professional Colombia
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 7/12/2010 Physician Japan
Primary
Concomitant
Agranulocytosis Life Threatening 6/22/2010 57 Male 7/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/1/2010 52 Female 99 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 6/23/2010 66 Female 90 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/1/2010 52 Female 99 lb 8/13/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 8/16/2010 Physician Japan
Primary
Concomitant
Shock Other Serious 1/6/2010 67 Female 115 lb 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Life Threatening 6/26/2010 64 Female 8/20/2010 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 5/1/2010 20 Female 8/26/2010 Consumer Colombia
Primary
Concomitant
Spondylitis Other Serious 6/2/2010 64 Female 8/27/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 9/13/2010 United States
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 9/27/2010 Physician Japan
Primary
Concomitant
Cerebellar Infarction Hospitalization 3/2/2010 66 Male 9/27/2010 Physician Japan
Primary
Concomitant
Premature Baby Hospitalization 8/17/2010 Male 4 lb 9/20/2010 Pharmacist Ireland
Primary
Concomitant
Premature Labour Hospitalization 9/1/2007 32 Female 163 lb 9/20/2010 Pharmacist Ireland
Primary
Concomitant
Osteonecrosis Hospitalization 7/8/2009 65 Female 99 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Spondylitis Other Serious 6/2/2010 64 Female 10/13/2010 Physician Japan
Primary
Secondary
Concomitant
Premature Labour Hospitalization 9/1/2007 32 Female 163 lb 10/4/2010 Pharmacist Ireland
Primary
Concomitant
Osteonecrosis Hospitalization 7/8/2009 65 Female 99 lb 10/26/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 223 lb 10/28/2010 United States
Primary
Concomitant
Aortic Dissection Hospitalization 11/26/2010 77 Female 95 lb 12/15/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 9/1/2009 20 Female 223 lb 12/29/2010 United States
Primary
Concomitant

Drug Data