Etoposide combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Systemic Candida Other Serious 45 Female 3/5/2007 Japan
Primary
Concomitant
Vomiting Disability 1/30/2007 7 Female 3/13/2007 Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 31 Male 4/4/2007 Other Health Professional United States
Primary
Secondary
Streptococcal Infection Other Serious 3/13/2007 63 Female 196 lb 5/24/2007 Other Health Professional United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 2/10/2001 12 Male 7/5/2007 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 2/10/2001 12 Male 7/5/2007 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/30/2007 7 Female 8/16/2007 Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 14 Male 9/19/2007 Japan
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 65 Female 11/26/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 1/1/2005 65 Female 11/20/2007 Consumer United States
Primary
Secondary
Oral Herpes Other Serious 1/1/2005 65 Female 11/29/2007 Consumer
Primary
Secondary
Lung Neoplasm Malignant Other Serious 9/1/2006 46 Male 12/7/2007
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Life Threatening 11/3/2007 16 Female 208 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 1/1/2005 65 Female 1/15/2008 Consumer United States
Primary
Secondary
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Serositis Death 1 3/6/2008 Consumer Japan
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 11 3/11/2008 Consumer Japan
Primary
Concomitant
Cytomegalovirus Enteritis Other Serious 12 3/11/2008 Consumer Japan
Primary
Concomitant
Stem Cell Transplant Other Serious 15 Unknown 3/13/2008 Japan
Primary
Concomitant
Stem Cell Transplant Death 1 3/13/2008 Japan
Primary
Concomitant
Serositis Death 1 3/24/2008 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 15 3/24/2008 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 11 3/24/2008 Physician Japan
Primary
Concomitant
Cytomegalovirus Enteritis Other Serious 12 3/24/2008 Physician Japan
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/3/2007 16 Female 208 lb 4/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 5 Male 4/10/2008 Other Health Professional Germany
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 5 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Pneumonia Aspiration Hospitalization 12/20/2007 1 Male 5/15/2008 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 2/29/2008 1 Female 7/2/2008 Japan
Primary
Concomitant
Skin Exfoliation Other Serious 9/10/2006 Male 174 lb 7/5/2008 Physician United States
Primary
Secondary
Stomatitis 2/3/2008 3 Female 7/16/2008 Japan
Primary
Concomitant
Vomiting 5/5/2008 12 Female 7/17/2008 Japan
Primary
Concomitant
Leukaemia Other Serious 39 Female 8/5/2008 United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 39 Female 8/5/2008 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 9/10/2006 Male 174 lb 8/7/2008 Physician United States
Primary
Secondary
Stem Cell Transplant Death 39 Female 8/9/2008 United States
Primary
Secondary
Stem Cell Transplant Disability 39 Female 8/20/2008 Physician United States
Primary
Secondary
Vomiting Life Threatening 3/3/2006 9 Female 9/8/2008 Japan
Primary
Concomitant
Recurrent Cancer Hospitalization 8/26/2008 29 Male 10/15/2008 Physician Korea, Republic Of
Primary
Concomitant
Vomiting Other Serious 8 Male 12/1/2008 Japan
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 1/1/2008 36 Female 134 lb 12/1/2008 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 2/10/2007 0 Female 12/4/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 2/10/2007 0 Female 12/9/2008 Japan
Primary
Concomitant
Wheezing Other Serious 4 Male 12/2/2009 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Liver Disease 1 Female 12/1/2009 Japan
Primary
Concomitant
Venoocclusive Liver Disease 1 Female 12/14/2009 Japan
Primary
Concomitant
Wheezing Other Serious 4 Male 12/21/2009 Other Health Professional Japan
Primary
Concomitant
Neutropenia Other Serious 17 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 1/19/2010 United Kingdom
Primary
Secondary
Tic Other Serious 13 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nephropathy Other Serious 1/1/2009 10 Male 2/5/2010 Other Health Professional United States
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vena Cava Injury Other Serious 9/1/2006 28 Male 3/4/2010
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 3/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Disorder Other Serious 16 Male 3/23/2010 Physician Japan
Primary
Concomitant
Tic Other Serious 13 Male 3/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Tic Other Serious Male 3/18/2010 United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 3/30/2010 Consumer United States
Primary
Secondary
Renal Failure Other Serious 3/30/2010 Consumer United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 3/30/2010 Consumer United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 3/30/2010 Consumer United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 3/30/2010 Consumer United States
Primary
Secondary
Thrombotic Microangiopathy Required Intervention 3/30/2010 United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 3/30/2010 United States
Primary
Secondary
Renal Failure Other Serious Unknown 3/30/2010 United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious Unknown 3/30/2010 United States
Primary
Secondary
Thrombotic Microangiopathy Required Intervention Unknown 3/30/2010 United States
Primary
Secondary
Respiratory Disorder Other Serious 7/6/2009 16 Male 110 lb 4/5/2010 Physician Japan
Primary
Concomitant
Pulmonary Congestion Hospitalization 5/4/2010 56 Male 234 lb 5/24/2010 Physician United States
Primary
Concomitant
Stem Cell Transplant Death 3/10/2008 59 Male 5/24/2010 Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/4/2010 56 Male 234 lb 6/4/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/4/2010 56 Male 234 lb 6/7/2010 Physician United States
Primary
Concomitant
Transfusion Reaction Other Serious 6/3/2006 9 Female 56 lb 6/2/2010 Physician United States
Primary
Secondary
Concomitant
Transfusion Reaction Other Serious 6/3/2006 9 Female 56 lb 6/3/2010 Physician United States
Primary
Secondary
Concomitant
Transfusion Reaction Other Serious 6/3/2006 9 Female 56 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 8/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Tic Other Serious 13 Male 9/2/2010 Consumer United Kingdom
Primary
Secondary
Tic Required Intervention 13 Male 8/27/2010 United Kingdom
Primary
Secondary
Sepsis Other Serious 4/20/2010 1 Male 15 lb 9/3/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 4/20/2010 1 Male 15 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 9/9/2010 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/1/2004 29 Male 9/9/2010 United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 13 Male 9/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 9/15/2010 Consumer United Kingdom
Primary
Secondary
Tic Other Serious 13 Male 9/3/2010 United Kingdom
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 66 Male 9/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/22/2010 14 Female 97 lb 10/22/2010 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 11/3/2010 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 5/6/2010 59 Female 99 lb 11/3/2010 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening Male 112 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening Male 112 lb 11/24/2010 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 8/21/2009 13 Male 97 lb 12/8/2010 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 8/18/2009 13 Male 97 lb 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 4/20/2010 1 Male 15 lb 12/10/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2010 69 Male 130 lb 12/30/2010 Physician Japan
Primary
Concomitant
Bacterial Infection Death 8/20/2009 46 Male 161 lb 1/3/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 8/11/2010 24 Male 141 lb 1/7/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Test Positive Death 5/1/2010 54 Female 119 lb 1/10/2011 Physician Japan
Primary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/10/2011 Physician Japan
Primary
Concomitant
Sepsis Death Female 170 lb 1/10/2011 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 1/10/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Death 8/6/2010 35 Female 71 lb 1/10/2011 Physician Japan
Primary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Hospitalization 5/1/2010 54 Female 119 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Adult T-cell Lymphoma/leukaemia Death Female 126 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 8/6/2010 35 Female 71 lb 1/14/2011 Physician Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 5/6/2010 59 Female 99 lb 1/26/2011 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 1/26/2011 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/17/2010 43 Female 119 lb 1/26/2011 Physician Japan
Primary
Concomitant
Eschar Death 63 Male 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 9 Female 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Hypoxia Death 2 Male 2/11/2011 Other Health Professional United States
Primary
Concomitant
Fungal Infection Hospitalization 6/24/2009 15 Male 126 lb 2/14/2011 Consumer Japan
Primary
Concomitant
Sepsis Hospitalization 7/22/2010 14 Female 97 lb 2/14/2011 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 17 Male 2/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neoplasm Malignant Death 60 Male 2/23/2011 Physician United States
Primary
Secondary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 5/6/2010 59 Female 99 lb 3/3/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Endothelial Dysfunction Other Serious 2 Male 2/25/2011 Physician United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/24/2010 19 Male 115 lb 3/10/2011 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 119 lb 3/10/2011 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 17 Male 3/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Hospitalization 5/17/2010 43 Female 119 lb 3/25/2011 Physician Japan
Primary
Concomitant
Pulmonary Granuloma Other Serious 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Stem Cell Transplant Death 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Microangiopathy Death 2 Male 4/1/2011 Other Health Professional United States
Primary
Concomitant
Thrombotic Microangiopathy Death 12 Female 6/10/2011 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 9 Male 6/13/2011 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/1991 16 Female 6/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 63 Male 6/15/2011 Other Health Professional United States
Primary
Secondary
Acanthamoeba Infection Other Serious 6/17/2011 Physician United States
Primary
Secondary
Leukopenia Hospitalization 63 Male 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 63 Male 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 26 Female 6/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious 2/10/2010 23 Male 117 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data