Tacrolimus combined with Trimethoprim + Sulfamethoxazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombotic Microangiopathy Hospitalization 1/8/2004 68 Male 176 lb 2/7/2006 Physician Spain
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome 11/20/2005 49 Male 1/23/2006 Pharmacist United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Vitamin A Increased Required Intervention 2/25/2006 41 Male 140 lb 3/15/2006 Pharmacist United States
Primary
Concomitant
Gastroenteritis Hospitalization 10/9/2005 55 Female 5/30/2006 Physician Germany
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 7/1/2006 Male 9/20/2006 Pharmacist United States
Primary
Concomitant
Gastroenteritis Hospitalization 10/9/2005 55 Female 10/6/2006 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Other Serious 2/25/2006 68 Male 9/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Cortical Necrosis Life Threatening 45 Female 2/15/2007 United States
Primary
Concomitant
Vascular Anomaly Hospitalization Female 5 lb 2/16/2007 Physician United States
Primary
Secondary
Concomitant
Vascular Anomaly Other Serious Female 5 lb 6/1/2007 Physician United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 7/1/2001 22 Female 9/24/2007
Primary
Secondary
Nephrogenic Systemic Fibrosis Other Serious 22 Female 9/26/2007 Physician United States
Primary
Concomitant
Liver And Pancreas Transplant Rejection Other Serious 10/14/2007 1 Male 23 lb 10/26/2007 Pharmacist Canada
Primary
Concomitant
Transplant Failure Other Serious 5/12/2006 45 Female 159 lb 2/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Meningitis Cryptococcal Other Serious 6/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/28/2008 Female 112 lb 5/29/2008 Pharmacist United States
Primary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Urosepsis Other Serious 6/25/2008 Colombia
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 63 Female 7/1/2008 Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 61 Male 7/1/2008 Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 59 Female 7/1/2008 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/16/2008 Other Health Professional United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 63 Female 8/7/2008 Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 59 Female 8/7/2008 Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 61 Male 8/7/2008 Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 61 Male 9/12/2008 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Death 61 Male 9/18/2008 Other Health Professional United States
Primary
Secondary
Septic Shock Other Serious 8/1/2008 58 Male 123 lb 10/16/2008 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/1/2008 58 Male 123 lb 10/17/2008 Physician Spain
Primary
Secondary
Concomitant
Tachycardia Other Serious 8/1/2008 Male 10/22/2008 Other Health Professional Spain
Primary
Concomitant
Septic Shock Other Serious 61 Male 12/10/2008
Primary
Secondary
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/3/2009 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/18/2008 58 Male 132 lb 3/5/2009 Physician Spain
Primary
Secondary
Concomitant
Tachycardia Other Serious 8/18/2008 58 Male 3/6/2009 Other Health Professional Spain
Primary
Concomitant
Pyrexia Hospitalization 54 Male 3/13/2009 Other Health Professional United States
Primary
Secondary
Atrial Fibrillation Other Serious 5/28/2004 Male 201 lb 4/3/2009 Physician Israel
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2007 41 Female 4/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 8/3/2008 30 Female 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/2/2009 Male 186 lb 2/12/2009 Pharmacist United States
Primary
Concomitant
Trichosporon Infection Other Serious 6/16/2009 United States
Primary
Secondary
Concomitant
Trichosporon Infection Other Serious 6/17/2009 United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/8/2004 Male 176 lb 6/23/2009 Physician Spain
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 10/8/2004 Male 185 lb 6/23/2009 Physician Spain
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 4/20/2009 59 Male 196 lb 4/22/2009 Pharmacist United States
Primary
Concomitant
Sudden Death Other Serious 7/6/2009 Other Health Professional United States
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/8/2004 70 Male 7/29/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 8/3/2008 30 Female 8/28/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/20/2009 67 Female 135 lb 7/17/2009 Pharmacist United States
Primary
Concomitant
Drug Level Increased Hospitalization 22 Female 10/14/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Wound Dehiscence Death 57 Male 10/15/2009 Physician Italy
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Hospitalization 10/5/2009 46 Male 10/30/2009 Physician United States
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 10/5/2009 46 Male 11/12/2009 Physician United States
Primary
Concomitant
Stenotrophomonas Infection Other Serious 45 Male 11/30/2009
Primary
Secondary
Transplant Rejection Hospitalization 64 Female 11/30/2009
Primary
Secondary
Neutropenia Other Serious 17 Male 1/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 31 Male 2/25/2010
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 62 Female 2/25/2010
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 75 Male 2/25/2010
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 24 Male 2/25/2010
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 37 Female 2/25/2010
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 46 Male 2/26/2010
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 34 Male 2/26/2010
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 17 Male 2/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vena Cava Injury Other Serious 9/1/2006 28 Male 3/4/2010
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 58 Male 3/5/2010
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 58 Female 3/9/2010 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 17 Male 3/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Heart Transplant Other Serious Male 7/1/2010 United Kingdom
Primary
Concomitant
Right Ventricular Failure Other Serious 1 7/15/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 10 7/15/2010 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Other Serious 64 Male 7/16/2010 Other Health Professional United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 7/16/2010 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Other Serious 7/19/2010 Other Health Professional United States
Primary
Concomitant
Glucose Tolerance Impaired Other Serious 7/19/2010 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Other Serious 64 Male 7/19/2010 Other Health Professional United States
Primary
Concomitant
Hypotension Other Serious 47 Female 7/19/2010 United States
Primary
Concomitant
Heart Transplant Life Threatening 5/1/2010 20 Male 7/14/2010 United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2009 50 Female 110 lb 7/29/2010 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/17/2010 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2009 50 Female 110 lb 8/19/2010 Other Health Professional Japan
Primary
Concomitant
Tachycardia Other Serious 65 Female 8/20/2010
Primary
Secondary
Renal Impairment Other Serious 20 Male 8/30/2010 Other Health Professional Sweden
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 3/11/2009 23 Female 97 lb 8/31/2010 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 9/24/2010 Other Health Professional United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 9/24/2010 Other Health Professional United States
Primary
Concomitant
Glucose Tolerance Impaired Other Serious 9/24/2010 Other Health Professional United States
Primary
Concomitant
Right Ventricular Failure Other Serious 1 9/24/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 10 9/24/2010 Other Health Professional United States
Primary
Concomitant
Abscess Fungal Hospitalization 50 Male 10/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 12/27/2008 52 Male 152 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 64 Female 11/2/2010 United States
Primary
Concomitant
Sepsis Other Serious 5/26/2009 7 Female 29 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 55 Female 11/12/2010 Other Health Professional United States
Primary
Concomitant
Cytomegalovirus Infection Other Serious 7/17/2009 28 Male 110 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 49 Male 11/15/2010 United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2010 12/2/2010 Other Health Professional United States
Primary
Concomitant
Pseudomonal Sepsis Other Serious 5/21/2010 Male 154 lb 12/3/2010 Physician Japan
Primary
Concomitant
Transplant Failure Other Serious 16 Female 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Transplant Failure Other Serious 12 Male 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 10 Female 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Enterocolitis Other Serious 12 Male 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 6 Male 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 11 Male 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 16 Female 12/20/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 11 12/21/2010 Other Health Professional Russian Federation
Primary
Concomitant
Cytomegalovirus Viraemia Other Serious 12 12/21/2010 Other Health Professional Russian Federation
Primary
Concomitant
Febrile Neutropenia Other Serious 10 12/21/2010 Other Health Professional Russian Federation
Primary
Concomitant
Cytomegalovirus Viraemia Other Serious 16 12/21/2010 Other Health Professional Russian Federation
Primary
Concomitant
Enterocolitis Other Serious 12 12/21/2010 Other Health Professional Russian Federation
Primary
Concomitant
Vomiting Other Serious 3/15/2010 54 Female 95 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 60 Male 12/10/2010 Other Health Professional Japan
Primary
Concomitant
Graft Dysfunction Other Serious 1/19/2011 Physician Canada
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 26 Male 1/20/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Transplant Failure Death 56 Male 1/24/2011 Physician United States
Primary
Concomitant
Vascular Pseudoaneurysm Ruptured Death 26 Female 1/24/2011 Physician United States
Primary
Concomitant
Death Other Serious 55 Female 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 26 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 26 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Infection Other Serious 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 27 Female 2/17/2011 Physician Japan
Primary
Secondary
Haemorrhage Intracranial Other Serious 3/2/2011 United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2010 48 Female 128 lb 3/28/2011 Other Health Professional United States
Primary
Concomitant
Engraftment Syndrome Other Serious 4/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 1/1/2007 4/18/2011 Physician France
Primary
Secondary
Concomitant
Rash Hospitalization 3/15/2010 54 Female 95 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Other Serious 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious 44 Male 4/21/2011 Other Health Professional United States
Primary
Concomitant
Adenovirus Infection Death 16 Male 4/22/2011 Other Health Professional Sweden
Primary
Concomitant
Drug Interaction Hospitalization 64 Female 5/20/2011 Pharmacist United States
Primary
Concomitant
Interacting
Histiocytosis Haematophagic Other Serious 16 Male 6/1/2011 Other Health Professional Sweden
Primary
Concomitant
Hepatotoxicity Hospitalization 64 Male 5/25/2011 Physician United States
Primary
Concomitant
Circulatory Collapse Death 67 7/25/2011 Physician United States
Primary
Secondary
Concomitant
Circulatory Collapse Death 61 Female 7/25/2011 Physician United States
Primary
Secondary
Concomitant
Circulatory Collapse Death 51 7/25/2011 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Other Serious 7/25/2011 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Other Serious 7/25/2011 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Other Serious 7/25/2011 Physician United States
Primary
Secondary
Concomitant
Oral Cavity Fistula Hospitalization 30 Male 8/4/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Lymphopenia Other Serious 2/1/2011 11 Male 8/11/2011 Physician Israel
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 49 Male 9/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Lymphocyte Count Decreased Other Serious 10/13/2003 44 Male 166 lb 9/29/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/11/2009 23 Female 97 lb 9/29/2011 Physician Japan
Primary
Concomitant
Acute Psychosis 52 Male 10/10/2011 United Kingdom
Primary
Concomitant
Pneumonia Aspiration Hospitalization 49 Male 10/6/2011 United Kingdom
Primary
Secondary
Nocardiosis Hospitalization 54 Female 10/19/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data