Azathioprine combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Hypoplasia Death 0 1/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Polyneuropathy Other Serious 56 Male 1/19/2006 Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 2/3/2006 France
Primary
Concomitant
Urine Output Decreased Other Serious 1/1/2006 28 Female 112 lb 3/28/2006 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 1/1/2006 Male 5 lb 3/28/2006 Physician United Kingdom
Primary
Concomitant
Transplant Rejection Other Serious 26 Male 4/12/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Tachycardia Required Intervention 9/6/2005 66 Male 1/9/2006 United States
Primary
Concomitant
Rash Pruritic Required Intervention 11/23/2005 60 Male 12/1/2005 Pharmacist United States
Primary
Concomitant
Transplant Rejection Other Serious 36 Male 6/12/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 1/1/2000 39 Male 7/20/2006 Other Health Professional Finland
Primary
Secondary
Vomiting Other Serious 25 Female 7/28/2006 Other Health Professional France
Primary
Secondary
Von Willebrand's Disease Hospitalization 38 Female 8/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Subcutaneous Nodule Death 60 Male 9/25/2006
Primary
Secondary
Death Other Serious 37 Male 10/7/2006 Physician Guatemala
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2006 38 Male 11/3/2006 Japan
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 42 Male 11/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 6/12/2006 69 Male 11/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 42 Male 12/4/2006 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/23/2006 Female 134 lb 12/15/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 11/24/2006 23 Female 97 lb 1/11/2007 Consumer United Kingdom
Primary
Concomitant
Interacting
Adenocarcinoma Hospitalization 9/9/2006 Female 148 lb 1/24/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/20/2006 69 Female 154 lb 1/25/2007 Physician United States
Primary
Concomitant
Oesophageal Squamous Cell Carcinoma Other Serious 54 Male 3/15/2007 Other Health Professional Germany
Primary
Secondary
Muscular Weakness Hospitalization 11/21/2006 68 Female 152 lb 3/21/2007 Pharmacist United States
Primary
Concomitant
Tri-iodothyronine Decreased Life Threatening 7/29/2006 Male 150 lb 3/29/2007 Other Health Professional Germany
Primary
Concomitant
Drug Level Decreased Life Threatening 1/1/2007 61 Male 163 lb 3/16/2007 Physician Germany
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Decreased Life Threatening 1/1/2007 61 Male 163 lb 3/27/2007 Physician Germany
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 2/11/2007 0 Female 5 lb 3/20/2007 Pharmacist United Kingdom
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 9/8/2006 64 Male 188 lb 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 36 Female 5/16/2007 Other Health Professional Belgium
Primary
Concomitant
Pathogen Resistance Hospitalization 3/29/2007 55 5/15/2007 United Kingdom
Primary
Secondary
Concomitant
Pleural Disorder Hospitalization 1/1/2003 58 Male 7/26/2007 Pharmacist Spain
Primary
Concomitant
Vomiting Hospitalization 7/23/2007 12 84 lb 8/14/2007 Other Health Professional Australia
Primary
Concomitant
Metastases To Pleura Hospitalization 1/1/2003 58 Male 8/2/2007 Pharmacist Spain
Primary
Concomitant
Vomiting Hospitalization 7/23/2007 12 84 lb 8/24/2007 Other Health Professional Australia
Primary
Concomitant
Intestinal Adenocarcinoma Hospitalization 9/21/2006 Female 148 lb 8/24/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 6/1/2002 42 Male 8/17/2007 Physician France
Primary
Concomitant
Post Procedural Complication Death 8/1/2006 51 Male 8/20/2007 Physician Czech Republic
Primary
Secondary
Post Procedural Complication Other Serious 8/1/2006 51 Male 8/29/2007 Physician Czech Republic
Primary
Secondary
Waist Circumference Increased Other Serious 1/1/2005 49 Male 8/27/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vertigo Other Serious 62 Female 8/31/2007 Physician France
Primary
Secondary
Transplant Rejection Other Serious 8/1/2006 51 Male 9/4/2007 Physician Czech Republic
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/20/2006 68 Female 154 lb 9/13/2007 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 4/1/1998 26 Male 146 lb 10/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 18 Male 10/23/2007
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/16/1996 53 Female 96 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Temporal Lobe Epilepsy Other Serious 4/25/2001 12 Female 104 lb 10/19/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/7/2007 Physician Norway
Primary
Concomitant
Renal Impairment Other Serious 11/20/2007 Physician Norway
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 23 Female 12/6/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 48 Male 12/6/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 46 Male 12/6/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 48 Male 12/13/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 46 Male 12/14/2007 Other Health Professional Japan
Primary
Secondary
Vascular Injury Other Serious 5/21/2007 65 Female 101 lb 11/30/2007 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 24 Female 12/20/2007 Netherlands
Primary
Concomitant
Rash Erythematous Other Serious 10/4/2007 Male 2/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Transplant Rejection Other Serious Male 1/17/2008 Physician Australia
Primary
Secondary
Splenomegaly Hospitalization 7/6/2007 Male 2/5/2008 Physician United Kingdom
Primary
Concomitant
Tenderness Hospitalization 39 Male 1/30/2008 Physician United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 8/1/1989 39 Female 2/21/2008
Primary
Secondary
Venoocclusive Liver Disease Other Serious 30 Female 2/25/2008
Primary
Secondary
Splenomegaly Hospitalization 7/6/2007 Male 2/28/2008 Physician United Kingdom
Primary
Concomitant
Rash Erythematous Other Serious 10/4/2007 Male 2/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/1/2007 56 Male 2/22/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Bronchiectasis Life Threatening 10/1/2007 49 Female 203 lb 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 3/7/2008 Consumer United Kingdom
Primary
Concomitant
Pain In Extremity 1/1/2006 Male 150 lb 3/15/2008 Consumer United States
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 3/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Maculo-papular Hospitalization 1/1/2007 56 Male 3/7/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12 Male 3/27/2008 Japan
Primary
Concomitant
Sepsis Hospitalization 7/21/2006 54 Male 134 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2005 25 Female 4/8/2008 Physician Austria
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 12 Male 4/7/2008 Japan
Primary
Concomitant
Hepatitis E Other Serious 1/1/2005 30 Female 4/17/2008 Netherlands
Primary
Secondary
Ventricular Hypokinesia Hospitalization 57 Male 4/10/2008 Physician Australia
Primary
Concomitant
Hepatic Cancer Metastatic Other Serious 1/22/2008 Male 4/18/2008 Physician Australia
Primary
Concomitant
Oesophageal Varices Haemorrhage Other Serious 4/12/1999 30 Female 4/21/2008 Physician Netherlands
Primary
Secondary
Trismus Death 45 Male 4/21/2008 Physician United States
Primary
Secondary
Concomitant
Surgical Procedure Repeated Hospitalization 40 Female 4/29/2008 Netherlands
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2/1/2005 18 Female 5/1/2008 Other Health Professional United States
Primary
Secondary
Urinary Incontinence Death 45 Male 5/1/2008 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 7/1/2005 65 Male 5/1/2008 Other Health Professional United States
Primary
Secondary
Venoocclusive Liver Disease Other Serious 5/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious 5 Female 5/13/2008
Primary
Secondary
Concomitant
Tumour Necrosis Other Serious 17 Male 5/9/2008 Physician Turkey
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 4/9/2008 13 Male 83 lb 5/21/2008 Other Health Professional Australia
Primary
Concomitant
Polyomavirus-associated Nephropathy Other Serious 28 Male 5/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/1/2004 34 Male 5/28/2008 Physician Turkey
Primary
Secondary
Concomitant
Transfusion Microchimerism Other Serious 9 Female 6/6/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Zygomycosis Death 25 Female 6/6/2008 Physician United States
Primary
Secondary
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Weight Decreased Other Serious 30 Female 7/18/2008 Brazil
Primary
Secondary
Dystonia Hospitalization 6/18/2008 Male 8/15/2008 Other Health Professional France
Primary
Secondary
Concomitant
Dystonia Hospitalization 6/18/2008 Male 8/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Premature Baby Congenital Anomaly Female Germany
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 9 Female 9/30/2008 Physician Australia
Primary
Secondary
Concomitant
Kaposi's Sarcoma Other Serious 49 Male 10/3/2008 Physician United States
Primary
Secondary
Visual Impairment Required Intervention 1/9/2008 21 Female 106 lb 10/7/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 28 Female 10/8/2008 Kuwait
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 15 Female 10/20/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Surgery Hospitalization 44 Male 10/20/2008 Other Health Professional Netherlands
Primary
Secondary
Transplant Rejection Other Serious 44 Male 10/13/2008 Physician Netherlands
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Hospitalization 6/1/2008 55 Male 143 lb 10/23/2008 Physician Spain
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Recurrent Other Serious 10/13/2008 Male 170 lb 10/30/2008 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious Female 10/20/2008 Physician United States
Primary
Concomitant
Premature Baby Hospitalization 6 lb 10/20/2008 Physician United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 44 Male 10/29/2008 Physician Netherlands
Primary
Secondary
Splenomegaly Other Serious 9 Male 11/12/2008 Other Health Professional United States
Primary
Secondary
Urinary Bladder Excision Other Serious 40 Female 11/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 22 Female 11/27/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Kidney Transplant Rejection Hospitalization 1/1/2005 40 Female 12/1/2008 United Kingdom
Primary
Secondary
Urinary Bladder Excision Other Serious 40 Female 11/25/2008 United Kingdom
Primary
Secondary
Polyomavirus-associated Nephropathy Hospitalization 40 Female 11/25/2008 United Kingdom
Primary
Secondary
Renal Impairment Other Serious 40 Female 12/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Kaposi's Sarcoma Other Serious 49 Male 12/11/2008
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 56 Male 12/9/2008 Physician United States
Primary
Secondary
Urinary Bladder Excision Other Serious 40 Female 12/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Human Herpesvirus 6 Infection Other Serious 43 Male 12/16/2008
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Other Serious 45 Female 12/22/2008 Physician Germany
Primary
Concomitant
Drug Toxicity Other Serious 22 Female 1/9/2009
Primary
Secondary
Sepsis Hospitalization 56 Male 1/14/2009
Primary
Secondary
Hepatic Neoplasm Malignant Recurrent Other Serious 10/13/2008 Male 170 lb 1/15/2009 Physician United Kingdom
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 26 Female 1/14/2009 United Kingdom
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 45 Male 1/22/2009 Physician Australia
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Hospitalization 1/1/2008 56 Male 1/28/2009 Physician United States
Primary
Secondary
Tuberculosis Hospitalization 60 Female 1/30/2009 United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious Female 2/5/2009 Other Health Professional Australia
Primary
Secondary
Vitamin D Deficiency Other Serious 45 Male 2/12/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 45 Male 2/23/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Death 39 Female 2/24/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Death 39 Female 3/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 26 Female 3/5/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Transplant Hospitalization 34 Male 3/11/2009 United Kingdom
Primary
Secondary
Tachycardia Hospitalization 60 Female 3/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 8/3/2008 30 Female 4/7/2009 Physician Australia
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 45 Male 4/7/2009 Other Health Professional Australia
Primary
Concomitant
Transplant Rejection Other Serious 1 Male 4/24/2009 Other Health Professional United States
Primary
Secondary
Thrombotic Microangiopathy Death 11/26/2008 13 Male 118 lb 4/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Death 39 Female 4/27/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 8/3/2008 30 Female 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 64 Male 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Visual Impairment Hospitalization 38 Female 5/21/2009 Physician United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 4/3/2006 Male 51 lb 6/4/2009 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 31 Male 6/8/2009 Physician Italy
Primary
Secondary
Small Intestinal Obstruction Life Threatening 1/1/2009 64 Male 6/9/2009 Physician United Kingdom
Primary
Secondary
Vomiting Other Serious 6/1/2000 Female 6/10/2009 Other Health Professional France
Primary
Secondary
Small Intestinal Obstruction Other Serious 64 Male 6/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Transitional Cell Carcinoma Hospitalization 46 Male 6/12/2009 Other Health Professional Australia
Primary
Secondary

Drug Data