Fludara combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oral Mucosal Disorder Hospitalization 2/9/2006 10 Male 8/7/2006 Consumer United States
Primary
Secondary
Concomitant
Oral Mucosal Disorder Hospitalization 2/9/2006 10 Male 8/30/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 40 Female 10/24/2007 Physician Japan
Primary
Concomitant
Status Epilepticus Life Threatening 2/10/2005 39 Male 10/26/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2005 60 Male 11/5/2007 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Life Threatening 10/22/2006 40 Female 12/10/2007 Physician Japan
Primary
Concomitant
Transplant Failure Death 6/5/2007 Physician United States
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 7/11/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 9/12/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 11/4/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 3/5/2005 64 Female 121 lb 12/12/2008 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/21/2008 56 Male 132 lb 4/15/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 1/30/2009 40 Male 110 lb 5/14/2009 Japan
Primary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 6/27/2008 44 Male 148 lb 8/17/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 1/30/2009 40 Male 110 lb 8/27/2009 Japan
Primary
Concomitant
Renal Impairment Death 12/1/2008 61 Male 115 lb 9/8/2009 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 1/30/2009 40 Male 110 lb 9/9/2009 Japan
Primary
Concomitant
Sepsis Other Serious 1/30/2009 40 Male 110 lb 9/11/2009 Japan
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/11/2008 56 Male 132 lb 9/24/2009 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 44 Female 10/20/2009 Other Health Professional Japan
Primary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Other Serious 1/1/2009 12 Male 10/23/2009 Other Health Professional Japan
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 12/1/2009 Other Health Professional Japan
Primary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Other Serious 2/1/2009 12 Male 12/2/2009 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 44 Female 12/7/2009 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Death 12/1/2008 61 Male 115 lb 2/12/2010 Physician Japan
Primary
Concomitant
Renal Impairment Death 12/1/2008 61 Male 115 lb 2/22/2010 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 1/1/2008 44 Female 4/20/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/20/2008 44 Female 6/21/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/12/2010 59 Male 132 lb 7/16/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 3/12/2010 59 Male 132 lb 7/19/2010 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 6/26/2006 54 Female 115 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/30/2009 22 Female 112 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/20/2008 44 Female 97 lb 8/3/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 9/2/2010 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4/30/2010 32 Female 9/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 9/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 8/10/2008 4 Male 26 lb 9/15/2010 Physician Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 9/16/2009 22 Male 169 lb 9/28/2010 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Death 5/1/2009 18 Female 110 lb 8/18/2010 Physician Japan
Primary
Concomitant
Stem Cell Transplant Death 5/19/2009 53 Female 101 lb 8/18/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Death 1/1/2009 50 Female 99 lb 8/18/2010 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 8/10/2008 4 Male 26 lb 10/27/2010 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 12/27/2008 52 Male 152 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 16 Female 10/29/2010 Physician Germany
Primary
Secondary
Concomitant
Oedema Life Threatening 1/29/2010 59 Male 176 lb 11/3/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 5/26/2009 7 Female 29 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 7/17/2009 28 Male 110 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 6/10/2010 2 Female 24 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening Male 112 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 3/1/2009 54 Male 152 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 4/23/2009 54 Female 115 lb 11/12/2010 Physician Japan
Primary
Concomitant
Shock Life Threatening 11/11/2007 12 Female 80 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Mouth Haemorrhage Death 4/25/2009 4 Female 32 lb 12/8/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 8/18/2009 13 Male 97 lb 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 16 Female 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Transplant Failure Other Serious 12 Male 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 10 Female 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Sepsis Other Serious 15 Male 12/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Enterocolitis Other Serious 12 Male 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 6 Male 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 11 Male 12/13/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 16 Female 12/20/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Vomiting Other Serious 3/15/2010 54 Female 95 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 11/7/2010 49 Female 97 lb 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Death 20 Male 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Fungal Death 1/4/2011 Physician United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 42 Male 1/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 11/11/2007 12 Female 80 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/13/2010 58 Male 121 lb 1/6/2011 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/6/2011 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Death 5/5/2010 48 Male 137 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Death 8/6/2010 67 Female 110 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Disease Progression Death 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Death 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Glossitis Hospitalization 9/13/2010 58 Male 121 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 1/10/2011 Physician United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Death 1/1/2010 52 Female 143 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 5/12/2009 56 Male 139 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Life Threatening 7/4/2010 73 Female 97 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Hospitalization 5/1/2010 54 Female 119 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 10/26/2009 59 Male 121 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Life Threatening 11/7/2009 66 Male 128 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Hospitalization 2/26/2010 56 Male 134 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Adult T-cell Lymphoma/leukaemia Death Female 126 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Liver Other Serious 3 Male 1/19/2011 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 35 Male 177 lb 1/24/2011 Pharmacist United States
Primary
Secondary
Concomitant
Infection Death 4/25/2009 4 Female 32 lb 1/24/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Male 117 lb 1/26/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 26 Male 1/27/2011 Physician Germany
Primary
Secondary
Concomitant
Sepsis Death 8/27/2010 57 Male 130 lb 1/31/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 4/22/2007 41 Male 132 lb 2/4/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 16 Female 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 3 Female 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 2/14/2008 17 Female 134 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 12 Male 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 16 Female 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 3 Female 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 9 Female 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 19 Male 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 12 Male 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 2 Female 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 7 Male 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 20 Male 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 7 Female 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious Female 2/11/2011 Physician Japan
Primary
Secondary
Concomitant
Fungal Infection Hospitalization 6/24/2009 15 Male 126 lb 2/14/2011 Consumer Japan
Primary
Concomitant
Sepsis Hospitalization 2/2/2008 61 Female 117 lb 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Hospitalization 3/27/2010 23 Male 117 lb 2/14/2011 Physician Japan
Primary
Secondary
Concomitant
Bk Virus Infection Other Serious 2 Female 2/17/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Liver Other Serious 9/22/2010 46 Female 64 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 2/18/2011 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 43 Female 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 66 Female 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 38 Male 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 72 Male 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Disease Progression Death 70 Male 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Hospitalization Female 66 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 76 Female 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 29 Female 2/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 7/19/2010 32 Female 108 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 52 Female 2/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 56 Female 2/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 48 Female 2/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 10/15/2010 7 Female 42 lb 2/23/2011 Physician Japan
Primary
Secondary
Concomitant
Aspergillosis Death 55 Female 2/23/2011 Physician United States
Primary
Secondary
Concomitant
Multi-organ Disorder Death 58 Male 2/23/2011 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 24 Male 2/23/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Fungal Death 52 Female 2/23/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 18 Female 2/23/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 63 Female 2/23/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data