Everolimus combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombotic Microangiopathy Other Serious 34 Male 117 lb 11/13/2007 India
Primary
Secondary
Concomitant
Renal Tubular Atrophy Other Serious 39 Male 9/17/2008 Other Health Professional Poland
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 54 3/20/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 61 3/20/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 54 3/20/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 55 3/20/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 64 3/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11/1/2007 5/6/2009 Other Health Professional Spain
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/1/2008 57 Male 5/6/2009 Other Health Professional Spain
Primary
Concomitant
Transplant Rejection Other Serious 41 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 41 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Interacting
Transplant Rejection Other Serious 41 6/26/2009 Physician United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 1/1/2007 53 Male 1/29/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Tubular Atrophy Other Serious 39 Male 2/4/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Peritoneal Disorder Hospitalization 4/29/2009 53 Male 163 lb 4/28/2010 Physician France
Primary
Concomitant
Transplant Rejection Other Serious 41 6/2/2010 Physician United States
Primary
Secondary
Transplant Rejection Other Serious 57 Male 8/16/2010 Other Health Professional France
Primary
Secondary
Blood Creatinine Increased Hospitalization 6/24/2010 16 Male 8/17/2010 Other Health Professional France
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 8/17/2010 Other Health Professional Greece
Primary
Secondary
Urinary Tract Infection Fungal Other Serious 12 Female 68 lb 8/25/2010
Primary
Secondary
Rhinitis Other Serious 38 Male 9/21/2010 Other Health Professional Italy
Primary
Secondary
Tinea Versicolour Other Serious 10/14/2010 Physician Turkey
Primary
Secondary
Squamous Cell Carcinoma Other Serious 1/1/2007 53 Male 10/13/2010 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 2/1/2006 3 Female 29 lb 11/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 12/3/2010 12/22/2010 Physician Italy
Primary
Concomitant
Renal Impairment Other Serious 1/1/2007 66 Female 12/27/2010 Physician Belgium
Primary
Concomitant
Bone Marrow Failure Other Serious 12/3/2010 12/30/2010 Physician Italy
Primary
Concomitant
Aphthous Stomatitis Other Serious 1/1/2007 66 Female 1/14/2011 Physician Belgium
Primary
Concomitant
Renal Impairment Other Serious 1/1/2007 66 Female 2/9/2011 Physician Belgium
Primary
Concomitant
Disorientation Hospitalization 12/12/2009 21 Male 110 lb 2/22/2011 Physician Germany
Primary
Secondary
Portal Hypertension Other Serious 8/3/2010 61 Male 3/7/2011 Physician Germany
Primary
Secondary
Liver Function Test Abnormal Hospitalization 9/29/2009 44 Male 4/13/2011 Physician Germany
Primary
Secondary
Concomitant Disease Progression Hospitalization 9/29/2009 44 Male 5/5/2011 Physician Germany
Primary
Secondary
Nausea Hospitalization 2/1/2006 3 Female 29 lb 5/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Injury Other Serious 7/28/2010 61 Male 5/16/2011 Physician Germany
Primary
Secondary
Chemical Peritonitis Hospitalization 2/3/2009 63 Male 157 lb 5/17/2011 Physician Italy
Primary
Secondary
Concomitant
Anaemia Hospitalization 9/29/2009 44 Male 5/20/2011 Physician Germany
Primary
Secondary
Hepatitis C Hospitalization 9/29/2009 44 Male 5/24/2011 Physician Germany
Primary
Secondary
Fluid Overload Disability 11/24/2009 66 Male 203 lb 5/26/2011 Physician Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 42 Male 5/24/2011 Other Health Professional Belgium
Primary
Concomitant
Neutropenic Sepsis Hospitalization 9/16/2010 59 Male 174 lb 7/8/2011 Physician Belgium
Primary
Secondary
Concomitant
Renal Impairment Other Serious 5 Female 8/9/2011 Other Health Professional Germany
Primary
Concomitant
Neutropenia Hospitalization 9/16/2010 59 Male 174 lb 9/9/2011 Physician Belgium
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/5/2010 57 Male 97 lb 9/15/2011 Physician Germany
Primary
Secondary
Concomitant
Death Death 3/24/2010 42 Male 161 lb 10/10/2011 Physician Germany
Primary
Secondary
Eye Pain Hospitalization 1/28/2010 62 Female 203 lb 10/10/2011 Physician Australia
Primary
Secondary
Liver Transplant Rejection Hospitalization 3/11/2010 24 Male 10/10/2011 Physician Germany
Primary
Secondary
Diabetes Mellitus Hospitalization 9/15/2009 69 Female 132 lb 10/10/2011 Physician Germany
Primary
Secondary
Biliary Ischaemia Hospitalization 12/7/2009 66 Male 150 lb 10/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant Disease Progression Hospitalization 3/24/2010 57 Male 10/10/2011 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/23/2010 46 Male 187 lb 10/11/2011 Physician Canada
Primary
Secondary
Liver Function Test Abnormal Hospitalization 9/29/2009 44 Male 10/11/2011 Physician Germany
Primary
Secondary
Biliary Ischaemia Hospitalization 6/4/2010 56 Male 119 lb 10/13/2011 Physician Germany
Primary
Secondary
Anxiety Hospitalization 8/10/2010 56 Female 174 lb 10/19/2011 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 5/4/2010 57 Male 187 lb 10/19/2011 Physician Netherlands
Primary
Secondary
Proteinuria Other Serious 52 Female 10/25/2011 Physician Poland
Primary
Secondary
Concomitant
Lung Infection Hospitalization 4/28/2009 66 Male 183 lb 11/9/2011 Physician Spain
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 9/16/2010 59 Male 174 lb 11/9/2011 Physician Belgium
Primary
Secondary
Concomitant
Tendonitis Life Threatening 4/16/2011 54 Male 143 lb 11/9/2011 Physician Australia
Primary
Secondary
Concomitant
Complications Of Transplanted Liver Hospitalization 3/10/2009 34 Male 209 lb 11/17/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Life Threatening 12/20/2010 60 Male 183 lb 11/28/2011 Physician Czech Republic
Primary
Secondary
Concomitant
Migraine Hospitalization 11/16/2011 53 Female 143 lb 11/28/2011 Physician Germany
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 52 Female 11/30/2011 Physician Poland
Primary
Secondary
Concomitant
Pneumonia Klebsiella Hospitalization 10/6/2011 61 Male 183 lb 12/5/2011 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Pneumonia Klebsiella Life Threatening 10/6/2011 61 Male 183 lb 12/8/2011 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Migraine Hospitalization 11/16/2011 53 Female 143 lb 12/9/2011 Physician Germany
Primary
Secondary
Concomitant
Hypertrichosis Other Serious 12/15/2011 Uruguay
Primary
Secondary
Hirsutism Other Serious 12/15/2011 Uruguay
Primary
Secondary
Chemical Peritonitis Hospitalization 2/3/2009 63 Male 157 lb 12/31/2011 Physician Italy
Primary
Secondary
Concomitant
Dyspnoea Disability 11/24/2009 66 Male 203 lb 1/6/2012 Physician Belgium
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9/16/2010 59 Male 174 lb 1/9/2012 Physician Belgium
Primary
Secondary
Concomitant
Gingival Hypertrophy Hospitalization 72 Male 1/20/2012 Other Health Professional Poland
Primary
Secondary
Drug Ineffective Hospitalization 3/11/2010 24 Male 1/30/2012 Physician Germany
Primary
Secondary
Renal Cyst Hospitalization 11/23/2009 66 Male 150 lb 2/2/2012 Other Health Professional Germany
Primary
Secondary
Bile Duct Stenosis Hospitalization 3/11/2010 24 Male 2/3/2012 Physician Germany
Primary
Secondary
Metabolic Encephalopathy Death 11/23/2009 66 Male 150 lb 2/3/2012 Physician Germany
Primary
Secondary
Monoparesis Hospitalization 1/26/2010 67 Male 159 lb 2/3/2012 Physician Germany
Primary
Secondary
Mesenteric Vein Thrombosis Hospitalization 5/4/2010 57 Male 187 lb 2/8/2012 Physician Netherlands
Primary
Secondary
Metabolic Encephalopathy Hospitalization 11/23/2009 66 Male 150 lb 2/8/2012 Other Health Professional Germany
Primary
Secondary
Death Death 3/24/2010 42 Male 161 lb 2/9/2012 Physician Germany
Primary
Secondary
Pyrexia Death 4/7/2010 43 Male 163 lb 2/9/2012 Physician Argentina
Primary
Secondary
Concomitant
Gastrointestinal Infection Hospitalization 4/7/2010 43 Male 163 lb 2/9/2012 Physician Argentina
Primary
Secondary
Concomitant
Liver Transplant Rejection Death 1/4/2010 47 Male 170 lb 2/10/2012 Physician Australia
Primary
Secondary
Liver Abscess Hospitalization 6/4/2010 56 Male 119 lb 2/13/2012 Physician Germany
Primary
Secondary
Hepatic Artery Stenosis Hospitalization 6/4/2010 56 Male 119 lb 2/20/2012 Physician Germany
Primary
Secondary
Death Death 3/24/2010 42 Male 161 lb 2/24/2012 Physician Germany
Primary
Secondary
Gingivitis Other Serious 5/4/2010 60 Female 159 lb 2/24/2012 Physician Australia
Primary
Secondary
Respiratory Failure Hospitalization 3/23/2010 46 Male 187 lb 2/27/2012 Physician Canada
Primary
Secondary
Renal Impairment Hospitalization 12/12/2008 64 Male 172 lb 2/28/2012 Physician Australia
Primary
Secondary
Concomitant Disease Progression Hospitalization 2/5/2010 45 Male 117 lb 3/13/2012 Physician France
Primary
Secondary
Concomitant
Asthenia Hospitalization 3/10/2009 34 Male 209 lb 3/13/2012 Physician Russian Federation
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/6/2011 61 Male 183 lb 3/13/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Hepatic Artery Stenosis Death 4/7/2010 43 Male 163 lb 3/13/2012 Physician Argentina
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/21/2010 52 Male 192 lb 3/14/2012 Physician Germany
Primary
Secondary
Neutropenic Sepsis Hospitalization 9/16/2010 59 Male 174 lb 3/14/2012 Physician Belgium
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 9/16/2010 59 Male 174 lb 3/14/2012 Physician Belgium
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 3/24/2010 57 Male 3/14/2012 Physician Germany
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 1/25/2010 67 Male 161 lb 3/13/2012 Physician Belgium
Primary
Secondary
Aspartate Aminotransferase Increased Hospitalization 8/27/2009 47 Female 123 lb 3/14/2012 Physician Russian Federation
Primary
Secondary
Concomitant
Obstructive Airways Disorder Hospitalization 3/4/2010 57 Male 3/13/2012 Physician France
Primary
Secondary
Concomitant
Migraine Hospitalization 11/16/2011 53 Female 143 lb 3/14/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/7/2010 43 Male 163 lb 4/2/2012 Physician Argentina
Primary
Secondary
Concomitant
Angiosarcoma Other Serious 59 Female 4/3/2012 Other Health Professional Turkey
Primary
Secondary
Bile Duct Stenosis Hospitalization 3/8/2010 24 Male 4/5/2012 Physician Germany
Primary
Secondary
Anaemia Hospitalization 9/29/2009 44 Male 4/5/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 12/20/2010 60 Male 183 lb 4/11/2012 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Scar Hospitalization 8/15/2009 62 Female 149 lb 4/13/2012 Physician Belgium
Primary
Secondary
Concomitant
Splenic Vein Thrombosis Hospitalization 5/4/2010 57 Male 187 lb 4/13/2012 Physician Netherlands
Primary
Secondary
Respiratory Failure Death 10/1/2010 40 Female 4/13/2012 Physician Australia
Primary
Concomitant
Septic Shock Hospitalization 11/24/2009 49 Male 170 lb 4/16/2012 Physician Brazil
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 12/19/2008 65 Male 165 lb 4/16/2012 Physician Germany
Primary
Secondary
Nephrotic Syndrome Hospitalization 9/29/2009 44 Male 4/17/2012 Physician Germany
Primary
Secondary
Aspergillosis Hospitalization 4/28/2009 66 Male 183 lb 4/17/2012 Physician Spain
Primary
Secondary
Concomitant
Chemical Peritonitis Hospitalization 2/3/2009 63 Male 157 lb 4/17/2012 Physician Italy
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 8/7/2009 29 Male 143 lb 4/17/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 7/24/2009 63 Male 137 lb 4/17/2012 Physician Italy
Primary
Secondary
Concomitant
Bacterial Infection Hospitalization 6/2/2009 68 Male 154 lb 4/17/2012 Physician Germany
Primary
Secondary
Blood Creatinine Increased Hospitalization 11/30/2009 41 Female 205 lb 4/17/2012 Physician Germany
Primary
Secondary
Klebsiella Sepsis Hospitalization 9/21/2010 73 Female 115 lb 4/18/2012 France
Primary
Secondary
Concomitant
Pyrexia Death 4/7/2010 43 Male 163 lb 4/20/2012 Physician Argentina
Primary
Secondary
Concomitant
Adverse Drug Reaction Hospitalization 3/23/2010 46 Male 187 lb 4/20/2012 Physician Canada
Primary
Secondary
Fatigue Hospitalization 3/23/2010 46 Male 187 lb 4/20/2012 Physician Canada
Primary
Secondary
Tremor Other Serious 2/8/2010 53 Male 143 lb 4/20/2012 Physician Australia
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 9/29/2009 44 Male 4/23/2012 Physician Germany
Primary
Secondary
Hepatic Artery Stenosis Hospitalization 6/4/2010 56 Male 119 lb 4/23/2012 Physician Germany
Primary
Secondary
Septic Shock Hospitalization 11/24/2009 49 Male 172 lb 4/30/2012 Physician Brazil
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 4/25/2012 67 Female 128 lb 5/10/2012 Physician Spain
Primary
Concomitant
Gingivitis Other Serious 5/4/2010 60 Female 159 lb 5/11/2012 Physician Australia
Primary
Secondary
Urosepsis Hospitalization 3/5/2010 63 Male 181 lb 5/11/2012 Physician Germany
Primary
Secondary
Concomitant
Hepatitis C Hospitalization 9/29/2009 44 Male 5/11/2012 Physician Germany
Primary
Secondary
Fall Hospitalization 1/9/2011 57 Male 5/14/2012 Physician Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/27/2009 47 Female 123 lb 5/14/2012 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Artery Stenosis Hospitalization 3/16/2010 63 Male 181 lb 5/14/2012 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/28/2010 62 Female 203 lb 5/14/2012 Physician Australia
Primary
Secondary
Dyspnoea Life Threatening 11/24/2009 66 Male 203 lb 5/14/2012 Physician Belgium
Primary
Secondary
Concomitant
Complications Of Transplanted Liver Life Threatening 10/6/2011 61 Male 183 lb 5/15/2012 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 12/20/2010 60 Male 183 lb 5/15/2012 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Liver Transplant Rejection Hospitalization 9/9/2009 44 Male 181 lb 5/16/2012 Physician Colombia
Primary
Secondary
Concomitant
Anaemia Hospitalization 6/30/2009 55 Female 161 lb 5/16/2012 Physician Spain
Primary
Secondary
Gingivitis Other Serious 5/4/2010 60 Female 159 lb 5/18/2012 Physician Australia
Primary
Secondary
Liver Transplant Rejection Hospitalization 11/24/2009 66 Male 203 lb 5/18/2012 Physician Belgium
Primary
Secondary
Concomitant
Hepatic Artery Thrombosis Other Serious 5/21/2012 Other Health Professional Germany
Primary
Concomitant
Renal Impairment Hospitalization 4/25/2012 67 Female 128 lb 6/1/2012 Physician Spain
Primary
Concomitant
Leukopenia Hospitalization 7/25/2008 50 Male 143 lb 5/31/2012 Physician Spain
Primary
Secondary
Abdominal Pain Hospitalization 7/25/2008 50 Male 143 lb 5/31/2012 Physician Spain
Primary
Secondary
Diarrhoea Hospitalization 2/1/2006 3 Female 29 lb 6/7/2012 Physician Japan
Primary
Secondary
Concomitant
Hepatic Cyst Other Serious 60 Female 6/8/2012 Other Health Professional Turkey
Primary
Concomitant
Renal Impairment Hospitalization 4/25/2012 67 Female 128 lb 6/22/2012 Physician Spain
Primary
Concomitant
Renal Impairment Hospitalization 4/25/2012 67 Female 128 lb 6/26/2012 Physician Spain
Primary
Concomitant
Skin Erosion Other Serious 68 Male 6/27/2012 Other Health Professional Italy
Primary
Secondary

Drug Data