Amphotericin B combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteopenia Hospitalization 8/4/2005 61 Male 2/17/2006 Physician Belgium
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Renal Failure Disability 15 Male 3/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 4/25/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 5/23/2006 Physician Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 8/7/2005 64 Male 7/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/31/2005 45 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 10/30/2006 Other Health Professional United States
Primary
Concomitant
Skin Ulcer Other Serious 57 Male 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Death 65 Male 11/7/2006 Physician United States
Primary
Secondary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 8/4/2005 61 Male 11/24/2006 Physician Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Osteopenia Hospitalization 8/4/2005 61 Male 12/26/2006 Physician Belgium
Primary
Secondary
Concomitant
Vomiting Other Serious 10 Male 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Shock Death Male 2/23/2007 Physician Germany
Primary
Concomitant
Osteopenia Hospitalization 8/4/2005 61 Male 3/1/2007 Physician Belgium
Primary
Secondary
Concomitant
Fatigue Hospitalization 7/13/2006 60 Male 4/4/2007 Physician France
Primary
Secondary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/13/2007 Physician Norway
Primary
Secondary
Concomitant
Cytomegalovirus Test Hospitalization 7/1/2005 65 Male 4/19/2007 Physician France
Primary
Secondary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/30/2007 Physician Norway
Primary
Secondary
Concomitant
Sepsis Other Serious 11/17/2005 40 Female 5/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 8/15/2007 1 Female 26 lb 9/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/8/2007 Other Health Professional Malaysia
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/12/2007 Other Health Professional Malaysia
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/1/2007 Other Health Professional Austria
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/2/2007 Other Health Professional Austria
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/2/2007 Other Health Professional Austria
Primary
Concomitant
Renal Artery Stenosis Hospitalization 10/24/2003 34 Male 161 lb 11/9/2007 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 8/22/2004 51 Male 152 lb 11/19/2007 Physician Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 49 Male 11/26/2007
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 8/22/2004 51 Male 152 lb 12/12/2007 Physician Germany
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 57 Male 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 49 Male 12/14/2007 Physician France
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 52 Male 1/16/2008
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 1/1/2006 49 Male 1/30/2008 Other Health Professional France
Primary
Secondary
Multi-organ Failure Other Serious 7 Male 2/26/2008 United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 4 Female 2/26/2008 United States
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious 12 Female 3/1/2008 Physician United States
Primary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Zygomycosis Other Serious 2/1/2007 47 Male 6/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Zygomycosis Other Serious 2/1/2007 47 Male 6/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Zygomycosis Other Serious 2/1/2007 47 Male 6/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Level Increased Other Serious 19 Female 7/11/2008 Other Health Professional United States
Primary
Secondary
Drug Level Increased Other Serious 9/21/2008 1 Female 22 lb 10/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Gastrointestinal Hypermotility Other Serious 9/21/2008 1 Female 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 4/1/2008 62 Male 11/7/2008 Physician Germany
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Increased Other Serious 9/21/2008 1 Female 11/6/2008 United Kingdom
Primary
Secondary
Concomitant
Skin Nodule Other Serious 1/1/2006 36 Female 12/1/2008 Other Health Professional Germany
Primary
Concomitant
Septic Shock Other Serious 61 Male 12/10/2008
Primary
Secondary
Visual Impairment Hospitalization 11/27/2008 Male 110 lb 12/26/2008 United States
Primary
Concomitant
Immunosuppressant Drug Level Increased Other Serious 12/12/2008 4 Male 1/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Level Increased Other Serious 9/21/2008 1 Female 1/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Subcutaneous Nodule Other Serious 49 Female 1/26/2009
Primary
Secondary
Concomitant
Cerebral Aspergillosis Other Serious 42 Male 3/4/2009
Primary
Secondary
Respiratory Failure Other Serious 2/11/2009 35 Male 174 lb 3/18/2009 Physician Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 2/11/2009 35 Male 174 lb 3/20/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 3/10/2009 26 Female 3/24/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/22/2007 58 Male 130 lb 4/1/2009 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/22/2007 58 Male 130 lb 4/6/2009 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/26/2007 58 Male 130 lb 4/7/2009 Physician Belgium
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 1/30/2004 Male 4/8/2009 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 2/11/2009 35 Male 174 lb 3/30/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 3/10/2009 26 Female 93 lb 4/7/2009 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2007 41 Female 4/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 1 Male 4/24/2009 Other Health Professional United States
Primary
Secondary
Respiratory Failure Hospitalization 38 Female 4/22/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 38 Female 5/21/2009 Physician United States
Primary
Secondary
Concomitant
Trichosporon Infection Other Serious 6/16/2009 United States
Primary
Secondary
Concomitant
Trichosporon Infection Other Serious 6/17/2009 United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 11/27/2008 Male 110 lb 6/22/2009 Japan
Primary
Concomitant
Soft Tissue Infection Hospitalization 8/19/2003 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/20/2003 Female 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Artery Stenosis Hospitalization 10/24/2003 Male 161 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Urosepsis Hospitalization 5/26/2004 Female 134 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Cyst Life Threatening 1/27/2004 Female 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Stomatitis Necrotising Hospitalization 2/2/2004 Female 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 5/20/2003 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/6/2003 Male 132 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 9/9/2004 Female 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Retention Life Threatening 7/5/2004 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/10/2004 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Bronchitis Hospitalization 3/31/2005 Female 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Ureteral Stent Insertion Hospitalization 3/3/2003 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 4/10/2005 Male 158 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 9/16/2004 Male 198 lb 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Vesical Fistula Other Serious 3/26/2003 Female 6/24/2009 Physician Germany
Primary
Secondary
Concomitant
Stomatitis Necrotising Hospitalization 2/2/2004 Female 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 5/2/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Urosepsis Hospitalization 5/26/2004 Female 7/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Suture Rupture Life Threatening 8/26/2004 33 Male 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/20/2003 50 Female 8/5/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 7/1/2004 64 Male 8/17/2009 Physician Germany
Primary
Secondary
Concomitant
Wound Dehiscence Death 57 Male 10/15/2009 Physician Italy
Primary
Secondary
Concomitant
Drug Ineffective Death 54 Male 1/22/2010 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 58 Female 3/9/2010 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/25/2010 49 Male 147 lb 2/10/2010 Pharmacist United States
Primary
Concomitant
Septic Shock Other Serious 29 Female 5/12/2010 Other Health Professional France
Primary
Secondary
Concomitant
Varicella Virus Test Positive Other Serious 9 Male 6/23/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 43 Male 104 lb 7/20/2010 Taiwan, Province Of China
Primary
Secondary
Concomitant
Staphylococcal Skin Infection Hospitalization 8 Male 7/28/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2009 50 Female 110 lb 7/29/2010 Other Health Professional Japan
Primary
Concomitant
Supraventricular Tachycardia Life Threatening 8/4/2010 Other Health Professional Algeria
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2009 50 Female 110 lb 8/19/2010 Other Health Professional Japan
Primary
Concomitant
Staphylococcal Skin Infection Other Serious 9 Male 8/20/2010 Other Health Professional Netherlands
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/13/2009 4 Female 31 lb 9/9/2010 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 43 Male 9/10/2010 Physician Australia
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 6/24/2009 15 Male 126 lb 9/23/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/10/2009 4 Female 31 lb 10/11/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 5/1/2010 48 Male 181 lb 11/2/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 11/3/2010 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 5/8/2010 63 Female 11/5/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Death 2/8/2010 38 Male 146 lb 11/8/2010 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 5/1/2010 48 Male 181 lb 11/19/2010 Physician Germany
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 7/17/2009 28 Male 110 lb 11/23/2010 Physician Japan
Primary
Concomitant
Multi-organ Failure Hospitalization 6/24/2009 15 Male 126 lb 11/23/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 6/10/2010 2 Female 24 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 5/14/2010 2 Female 24 lb 11/29/2010 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Life Threatening 2/19/2010 7 Male 51 lb 12/13/2010 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 5/8/2010 63 Female 12/17/2010 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/13/2009 4 Female 31 lb 12/20/2010 Physician Japan
Primary
Concomitant
Transplant Rejection Hospitalization 4/1/2008 62 Male 12/29/2010 Physician Germany
Primary
Secondary
Concomitant
Candidiasis Hospitalization 26 Male 1/6/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/28/2010 30 Female 99 lb 1/6/2011 Physician Japan
Primary
Concomitant
Haemorrhage Death 4/13/2009 4 Female 31 lb 1/7/2011 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Death 1/1/2010 1/7/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Death 8/11/2010 24 Male 141 lb 1/7/2011 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 7/12/2010 52 Male 115 lb 1/10/2011 Physician Japan
Primary
Concomitant
Adult T-cell Lymphoma/leukaemia Death Female 126 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Heat Illness Hospitalization 26 Male 1/14/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 26 Male 1/20/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2009 18 Male 137 lb 1/24/2011 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 1/26/2011 Physician Japan
Primary
Concomitant
Lymphopenia Hospitalization 16 1/28/2011 Physician Israel
Primary
Secondary
Concomitant
Movement Disorder Other Serious 26 Male 1/31/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 2/11/2009 35 Male 174 lb 1/17/2011 Physician Japan
Primary
Concomitant
Infection Other Serious 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 16 2/7/2011 Physician Israel
Primary
Secondary
Concomitant
Fungal Infection Hospitalization 6/24/2009 15 Male 126 lb 2/14/2011 Consumer Japan
Primary
Concomitant
Sepsis Other Serious 9/10/2009 18 Male 137 lb 2/15/2011 Physician Japan
Primary
Concomitant
Haematemesis Other Serious 14 Male 2/9/2011 Physician United States
Primary
Secondary
Engraftment Syndrome Other Serious 4/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Enteritis Other Serious 4/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Enteritis Other Serious 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Other Serious 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data