Rabeprazole Sodium combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Treatment Noncompliance 7/13/2005 Female 121 lb 8/4/2006 Other Health Professional United States
Primary
Concomitant
Therapy Non-responder Death 2/1/2006 74 Female 11/21/2006 Physician Japan
Primary
Concomitant
Stress Other Serious 12/21/2006 80 Female 81 lb 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
Trigeminal Neuralgia Hospitalization 2/26/2007 Female 9/11/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 7/1/2006 77 Male 143 lb 10/25/2007 Physician Japan
Primary
Concomitant
Vascular Graft Hospitalization 9/21/2005 73 Female 11/9/2007 Physician Japan
Primary
Concomitant
Metabolic Acidosis Other Serious 9/1/2007 67 Female 97 lb 11/28/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 6/27/2007 69 Female 100 lb 11/27/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Death 6/7/2006 77 Male 143 lb 12/27/2007 Physician Japan
Primary
Concomitant
Metabolic Acidosis Other Serious 9/1/2007 67 Female 97 lb 1/21/2008 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 6/27/2007 69 Female 100 lb 1/25/2008 Physician Japan
Primary
Concomitant
Meningitis Hospitalization 6/27/2007 Female 110 lb 2/15/2008 Physician Japan
Primary
Concomitant
Meningitis Hospitalization 6/27/2007 Female 110 lb 2/21/2008 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 1/14/2008 44 Female 216 lb 3/19/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 1/3/2008 36 Female 134 lb 3/14/2008 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Hospitalization 1/3/2008 36 Female 134 lb 4/8/2008 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Hospitalization 1/3/2008 36 Female 134 lb 4/18/2008 Physician Japan
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 1/1/2008 36 Female 134 lb 6/10/2008 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 1/11/2008 85 Female 6/24/2008 Physician Japan
Primary
Secondary
Concomitant
Tremor Hospitalization 10/18/2007 44 Female 118 lb 8/7/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 9/12/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 10/12/2008 Female 10/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 4/21/2007 69 Female 82 lb 11/4/2008 Physician Japan
Primary
Secondary
Concomitant
Viral Pharyngitis Hospitalization 10/12/2008 Female 11/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/26/2007 Male 185 lb 11/26/2008 Canada
Primary
Secondary
Concomitant
Peritonitis Lupus Hospitalization 9/12/2007 29 Male 116 lb 12/24/2008 Physician Japan
Primary
Concomitant
Retroperitoneal Fibrosis Hospitalization 9/12/2007 29 Male 116 lb 1/22/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 3/11/2009 Other Health Professional Canada
Primary
Concomitant
Renal Failure Acute Other Serious 11/26/2007 4/10/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/10/2008 4/20/2009 Other Health Professional Canada
Primary
Concomitant
Renal Failure Acute Other Serious 11/26/2007 4/20/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 10/9/2007 Male 5/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/26/2007 47 5/14/2009 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 43 5/25/2009 Other Health Professional Canada
Primary
Concomitant
Varicella Life Threatening 5/13/2007 18 Female 110 lb 6/8/2009 Physician Japan
Primary
Secondary
Concomitant
Ileitis Hospitalization 5/20/2009 45 Male 127 lb 6/4/2009 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 12/3/2007 Male 7/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 10/4/2008 Male 106 lb 9/17/2009 Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/14/2009 Female 80 lb 10/8/2009 Japan
Primary
Concomitant
Vomiting Other Serious 9/1/2007 49 Female 99 lb 10/6/2009 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 10/4/2008 Male 106 lb 10/28/2009 Japan
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 1/8/2009 62 Female 117 lb 11/13/2009 Physician Japan
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 1/8/2009 62 117 lb 12/2/2009 Physician Japan
Primary
Secondary
Concomitant
Vitreous Floaters Other Serious 9/10/2009 Male 175 lb 1/14/2010 Physician Canada
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/3/2007 23 Female 128 lb 1/26/2010 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 1/8/2009 62 Female 117 lb 1/29/2010 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 1/8/2009 62 Female 117 lb 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 1/1/2005 3/3/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2005 3/8/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2005 3/15/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 10/10/2009 21 Female 172 lb 3/17/2010 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 7/1/2009 Female 3/29/2010 Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2010 33 Male 99 lb 4/1/2010 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 10/10/2009 21 Female 172 lb 4/1/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2010 33 Male 99 lb 4/9/2010 Physician Japan
Primary
Concomitant
Somnolence Other Serious 12/1/2004 4/12/2010 Physician United States
Primary
Concomitant
Chronic Graft Versus Host Disease Death 7/1/2009 65 Female 4/20/2010 Italy
Primary
Concomitant
Tremor Other Serious 9/1/2007 49 Female 99 lb 4/26/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 12/18/2009 68 Female 5/19/2010 Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/1/2010 63 Male 159 lb 5/26/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 12/1/2004 6/14/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/20/2010 63 Male 159 lb 6/11/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2004 6/23/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2004 29 Male 7/9/2010 Other Health Professional United States
Primary
Concomitant
Henoch-schonlein Purpura Hospitalization 12/20/2008 17 Female 88 lb 8/2/2010 Other Health Professional Japan
Primary
Concomitant
Drug Level Increased Other Serious 34 Male 8/17/2010 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2004 29 Male 8/17/2010 United States
Primary
Concomitant
Chronic Graft Versus Host Disease Death 7/1/2009 65 Female 8/24/2010 Other Health Professional Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2004 29 Male 9/9/2010 United States
Primary
Concomitant
Chronic Graft Versus Host Disease Death 7/1/2009 65 Female 9/13/2010 Italy
Primary
Concomitant
Transplant Failure Other Serious 4/14/2006 44 Male 9/14/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 10/8/2008 20 Female 133 lb 10/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious 4/14/2006 44 Male 11/5/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/17/2010 Male 168 lb 11/22/2010 Physician Japan
Primary
Concomitant
Transplant Failure Other Serious 4/14/2006 44 Male 11/16/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3/15/2010 54 Female 95 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 54 Female 95 lb 12/27/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Fungal Hospitalization 7/26/2010 51 Male 198 lb 1/3/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Artery Thrombosis Life Threatening 10/5/2010 54 Female 143 lb 1/4/2011 France
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 10/18/2007 44 Female 118 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Artery Thrombosis Life Threatening 10/5/2010 54 Female 143 lb 4/19/2011 France
Primary
Secondary
Concomitant
Rash Hospitalization 3/15/2010 54 Female 95 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Fungal Infection Other Serious 10/13/2009 36 Male 143 lb 4/27/2011 Physician Japan
Primary
Concomitant
Pruritus Hospitalization 3/12/2010 54 Female 95 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Candida Test Positive Hospitalization 3/12/2010 54 Female 95 lb 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 3/8/2011 31 Male 5/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Life Threatening 12/6/2010 53 Male 165 lb 5/27/2011 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 6/3/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 1/17/2010 55 Male 168 lb 6/6/2011 Consumer Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/17/2010 55 Male 168 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Hospitalization 6/1/2010 69 Male 137 lb 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 5/6/2011 62 Male 157 lb 6/7/2011 Physician Japan
Primary
Concomitant
Interacting
Drug Ineffective Hospitalization 6/1/2010 69 Male 137 lb 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Level Increased Other Serious 5/6/2011 62 Male 157 lb 6/20/2011 Physician Japan
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Death 12/18/2010 81 Male 78 lb 6/22/2011 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 12/18/2010 81 Male 78 lb 7/11/2011 Physician Japan
Primary
Concomitant
Adenovirus Infection Hospitalization 8/26/2008 50 Male 141 lb 7/27/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 5/1/2011 62 Male 8/3/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Renal Disorder Hospitalization 3/1/2011 59 Female 8/9/2011 Physician Japan
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 4/12/2011 78 Female 132 lb 8/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Myalgia Hospitalization 10/8/2008 20 Female 133 lb 9/1/2011 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 8/27/2008 43 Male 131 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 8/27/2008 43 Male 131 lb 9/22/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 9/21/2010 37 Female 102 lb 10/13/2011 Physician Japan
Primary
Secondary
Concomitant
Interacting
Staphylococcal Sepsis Life Threatening 10/13/2009 36 Male 143 lb 11/7/2011 Physician Japan
Primary
Concomitant
Enteritis Other Serious 2/23/2011 16 Female 85 lb 11/14/2011 Physician Japan
Primary
Concomitant
Radiation Injury Hospitalization 5/3/2011 60 Female 110 lb 11/18/2011 Physician Japan
Primary
Concomitant
Basal Cell Carcinoma Hospitalization 4/4/2011 59 Male 185 lb 11/18/2011 Australia
Primary
Concomitant
Liver Disorder Other Serious 12/7/2009 21 Male 132 lb 12/1/2011 Physician Japan
Primary
Concomitant
Basal Cell Carcinoma Hospitalization 4/4/2011 59 Male 185 lb 12/5/2011 Australia
Primary
Concomitant
Enteritis Other Serious 2/23/2011 16 Female 85 lb 12/9/2011 Physician Japan
Primary
Concomitant
Ileus Hospitalization 5/3/2011 60 Female 110 lb 12/22/2011 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Disability 3/14/2011 25 Male 123 lb 1/3/2012 Physician Japan
Primary
Concomitant
Hyperglycaemia Hospitalization 6/13/2009 74 Female 1/3/2012 Japan
Primary
Secondary
Concomitant
Pneumonia Death 12/21/2005 61 Female 136 lb 1/26/2012 Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 5/3/2011 60 Female 110 lb 1/30/2012 Physician Japan
Primary
Concomitant
Renal Disorder Disability 8/19/2011 50 Female 112 lb 2/9/2012 Physician Japan
Primary
Concomitant
Atrial Fibrillation Hospitalization 6/1/2011 68 Female 2/13/2012 Physician Japan
Primary
Concomitant
Enteritis Other Serious 2/23/2011 16 Female 85 lb 2/29/2012 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 8/19/2011 50 Female 112 lb 3/1/2012 Physician Japan
Primary
Concomitant
Respiratory Failure Death 7/21/2004 55 Female 3/2/2012 Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Recurrent Death 9/21/2005 59 Male 3/5/2012 Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/17/2010 55 Male 168 lb 3/7/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 1/17/2010 55 Male 168 lb 3/12/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder 8/19/2011 50 Female 112 lb 3/19/2012 Physician Japan
Primary
Concomitant
Dizziness 1/28/2011 57 Female 7/5/2011 Other Health Professional United States
Primary
Concomitant
Urticaria 1/28/2011 57 Female 7/5/2011 Other Health Professional United States
Primary
Concomitant
Liver Disorder Disability 7/9/2011 59 Female 126 lb 3/28/2012 Physician Japan
Primary
Secondary
Concomitant
Post Transplant Lymphoproliferative Disorder Disability 3/14/2011 25 Male 123 lb 4/2/2012 Physician Japan
Primary
Concomitant
Headache Other Serious 12/1/2004 29 Male 4/17/2012 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 4/1/2010 47 Female 130 lb 4/13/2012 Lawyer United States
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1/1/2010 36 Male 128 lb 4/19/2012 Physician Japan
Primary
Concomitant
Cardiovascular Disorder Hospitalization 1/21/2008 27 Male 4/19/2012 Physician Japan
Primary
Secondary
Concomitant
Gastroenteritis Staphylococcal Other Serious 7/1/2011 70 Female 108 lb 5/1/2012 Physician Japan
Primary
Concomitant
Blood Urea Increased Other Serious 5/30/2007 55 Female 121 lb 5/1/2012 Physician Japan
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Hospitalization 4/4/2011 59 Male 185 lb 5/15/2012 Australia
Primary
Concomitant
Squamous Cell Carcinoma Hospitalization 4/4/2011 59 Male 185 lb 5/17/2012 Australia
Primary
Concomitant
Drug Eruption Other Serious 4/25/2012 46 Female 82 lb 6/4/2012 Physician Japan
Primary
Concomitant
Squamous Cell Carcinoma Hospitalization Male 185 lb 6/26/2012 Physician Australia
Primary
Concomitant
Drug Eruption Other Serious 4/25/2012 46 Female 82 lb 6/26/2012 Physician Japan
Primary
Concomitant
Bronchitis Chronic Other Serious 4/5/2010 39 Female 101 lb 6/18/2012 Physician Japan
Primary
Secondary
Concomitant
Lupus Nephritis Other Serious 2/1/2008 23 Female 107 lb 6/22/2012 Physician Japan
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 6/9/2010 51 Female 7/6/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Life Threatening 4/1/2012 60 Male 130 lb 7/11/2012 Other Health Professional Canada
Primary
Concomitant
Thrombosis Other Serious 12/22/2011 78 Male 7/10/2012 Physician Japan
Primary
Concomitant
Beta-n-acetyl-d-glucosaminidase Increased Other Serious 5/15/2008 57 Female 121 lb 7/24/2012 Physician Japan
Primary
Concomitant
Malaise Other Serious 12/1/2004 29 Male 7/30/2012 Lawyer United States
Primary
Concomitant
Cystitis Hospitalization 8/4/2012 59 Female 8/15/2012 Physician Japan
Primary
Concomitant
Graft Loss Hospitalization 12/27/2011 13 Male 60 lb 8/20/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data