Cyclosporine combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Life Threatening 12/23/2003 Male 1/12/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Transplant Other Serious 8/29/2005 Male 1/13/2006 Physician Finland
Primary
Concomitant
Polyneuropathy Other Serious 56 Male 1/19/2006 Germany
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 12/23/2003 Male 1/19/2006 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/23/2003 Male 1/19/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2004 63 Male 2/1/2006 Hong Kong
Primary
Secondary
Subdural Haematoma Other Serious 12/23/2003 Male 2/9/2006 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 8/31/1999 42 Male 2/10/2006 Belgium
Primary
Concomitant
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 26 Male 4/12/2006 Physician United Kingdom
Primary
Concomitant
Septic Shock Death 40 Female 115 lb 4/28/2006 Physician Japan
Primary
Concomitant
Tachyarrhythmia Other Serious 7/1/2004 64 Male 5/20/2006 Consumer Germany
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 36 Male 6/12/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pain Other Serious 42 Female 6/12/2006 Japan
Primary
Secondary
Pain Other Serious 42 Female 6/16/2006 Japan
Primary
Secondary
Skin Exfoliation Other Serious 2 Male 6/29/2006 United States
Primary
Concomitant
Urinary Retention Other Serious 3/15/2005 64 Male 7/8/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/1996 43 Female 7/17/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 11/1/2001 52 Male 7/17/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 1/1/2000 39 Male 7/20/2006 Other Health Professional Finland
Primary
Secondary
Vomiting Other Serious 25 Female 7/28/2006 Other Health Professional France
Primary
Secondary
Thrombotic Microangiopathy Other Serious 41 Male 8/4/2006 Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 33 Male 8/3/2006 Japan
Primary
Secondary
Von Willebrand's Disease Hospitalization 38 Female 8/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 38 Female 8/11/2006 France
Primary
Secondary
Concomitant
Nocardia Sepsis Other Serious 46 Male 8/18/2006 Turkey
Primary
Secondary
Liver Transplant Rejection Other Serious 53 Male 9/30/2006 Other Health Professional Argentina
Primary
Concomitant
Soft Tissue Inflammation Hospitalization 7/1/2003 49 Female 10/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Trichosporon Infection Death 42 Male 10/9/2006 Japan
Primary
Secondary
Concomitant
Melaena Other Serious 1/1/2004 41 Female 10/17/2006 Japan
Primary
Secondary
Concomitant
Trichosporon Infection Death 42 Male 10/17/2006 Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/1/2005 38 Male 10/23/2006 Japan
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 31 Female 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2006 38 Male 11/3/2006 Japan
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 57 Male 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 23 Male 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombotic Microangiopathy Death 51 Male 11/10/2006 Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 6/1/2005 6 Male 1/9/2007 Japan
Primary
Secondary
Renal Failure Other Serious 11/24/2006 23 Female 97 lb 1/11/2007 Consumer United Kingdom
Primary
Concomitant
Interacting
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 1/30/2007 Japan
Primary
Concomitant
Colitis Ulcerative Other Serious 12/19/2006 Male 2/1/2007 Physician Czech Republic
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Ureteric Operation Hospitalization 9/14/2006 36 Male 2/12/2007 Consumer Australia
Primary
Secondary
Disease Progression Other Serious 45 Female 2/27/2007 Japan
Primary
Concomitant
Postrenal Failure Other Serious 35 Male 2/27/2007 Japan
Primary
Concomitant
Postrenal Failure Other Serious 35 Male 2/27/2007 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 15 Female 3/3/2007 Japan
Primary
Secondary
Chronic Graft Versus Host Disease Other Serious 48 Male 3/3/2007 Japan
Primary
Concomitant
Weight Decreased Other Serious 48 Male 3/10/2007 Japan
Primary
Secondary
Concomitant
Systemic Candida Death 45 Female 3/14/2007 Japan
Primary
Concomitant
Ureteric Stenosis Other Serious 35 Male 3/14/2007 Japan
Primary
Secondary
Concomitant
Oesophageal Squamous Cell Carcinoma Other Serious 59 Male 3/15/2007 Other Health Professional Germany
Primary
Secondary
Oesophageal Squamous Cell Carcinoma Other Serious 54 Male 3/15/2007 Other Health Professional Germany
Primary
Secondary
White Blood Cell Count Decreased Other Serious 15 Female 3/15/2007 Japan
Primary
Secondary
Concomitant
Undifferentiated Sarcoma Life Threatening 15 Male 3/26/2007 Physician Japan
Primary
Secondary
Concomitant
Ureteric Stenosis Other Serious 35 Male 3/28/2007 Japan
Primary
Secondary
Concomitant
Ureteric Stenosis Hospitalization 9/14/2006 36 Male 5/17/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Tachyarrhythmia Other Serious 7/1/2004 64 Male 5/18/2007 Consumer Germany
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 18 Female 6/13/2007 Other Health Professional Germany
Primary
Secondary
White Blood Cell Disorder Other Serious 1/1/2006 64 Female 101 lb 6/20/2007 Consumer Brazil
Primary
Secondary
Concomitant
Tremor Other Serious 54 Male 7/11/2007 Other Health Professional France
Primary
Secondary
Wound Infection Hospitalization 65 Female 7/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 40 Male 7/30/2007 Physician Kuwait
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 4/17/2007 Male 185 lb 8/3/2007 Physician Austria
Primary
Concomitant
Mucormycosis Death Male 8/6/2007 Japan
Primary
Secondary
Zygomycosis Hospitalization 10/1/2005 Male 8/14/2007 Japan
Primary
Secondary
Lung Infiltration Other Serious 4/17/2007 Male 185 lb 8/17/2007 Physician Austria
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 2/1/2003 27 Male 1/15/2007 Physician Austria
Primary
Concomitant
Death Life Threatening 50 Male 8/30/2007 Consumer United States
Primary
Secondary
Concomitant
Lung Infiltration Other Serious 4/17/2007 Male 185 lb 8/30/2007 Physician Austria
Primary
Concomitant
Keratoconjunctivitis Sicca Other Serious 6/1/2007 54 Female 9/11/2007 Netherlands
Primary
Secondary
Concomitant
Stomatitis Life Threatening 5/6/2007 56 Female 9/18/2007 Japan
Primary
Secondary
Concomitant
Lung Infiltration Other Serious 4/17/2007 Male 185 lb 10/1/2007 Physician Austria
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/8/2007 Other Health Professional Malaysia
Primary
Concomitant
Pericardial Disease Other Serious 54 Female 9/24/2007 Netherlands
Primary
Secondary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/12/2007 Other Health Professional Malaysia
Primary
Concomitant
Transitional Cell Carcinoma Other Serious 12 Male 10/17/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 11/1/2007
Primary
Secondary
Drug Interaction Other Serious 45 Female 11/6/2007 Japan
Primary
Concomitant
Interacting
Renal Impairment Other Serious 11/7/2007 Physician Norway
Primary
Concomitant
Renal Artery Stenosis Hospitalization 10/24/2003 34 Male 161 lb 11/9/2007 Physician Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 34 Male 117 lb 11/13/2007 India
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 1 Female 11/14/2007
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/20/2007 Physician Norway
Primary
Concomitant
Thyroiditis Other Serious 50 Male 11/26/2007 Other Health Professional Saudi Arabia
Primary
Secondary
Erythema Infectiosum Other Serious 32 Male 12/7/2007
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/1/2001 52 Male 12/10/2007 Japan
Primary
Concomitant
Vital Capacity Decreased Other Serious 4/1/2003 17 Female 12/14/2007 Other Health Professional Japan
Primary
Concomitant
Liver Transplant Rejection Other Serious 58 Female 12/14/2007 Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 57 Male 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 24 Female 12/20/2007 Netherlands
Primary
Concomitant
Viral Infection Death 11/30/2007 51 Female 106 lb 12/28/2007 Physician Belgium
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 31 Male 12/20/2007 Physician United States
Primary
Concomitant
Liver Transplant Rejection Other Serious 58 Female 1/10/2008 Japan
Primary
Secondary
Concomitant
Intention Tremor Other Serious 58 Female 1/15/2008 Physician Japan
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Brain Abnormal Death 11 Female 1/22/2008 Other Health Professional Saudi Arabia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/23/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 68 Male 1/22/2008 Physician United States
Primary
Concomitant
Kidney Transplant Rejection Other Serious 31 Unknown 2/1/2008 Poland
Primary
Concomitant
Rash Other Serious 61 Male 2/15/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Splenomegaly Other Serious 8/1/1989 39 Female 2/21/2008
Primary
Secondary
Renal Failure Other Serious 2/22/2008 Other Health Professional United States
Primary
Secondary
Renal Failure Other Serious 49 Male 2/25/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Interacting
Venoocclusive Liver Disease Other Serious 30 Female 2/25/2008
Primary
Secondary
Multi-organ Failure Other Serious 7 Male 2/26/2008 United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 2/29/2008 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Other Serious 47 Male 2/18/2008 Physician Australia
Primary
Concomitant
Pulmonary Oedema Other Serious 3/7/2008 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 49 Female 3/10/2008 Other Health Professional Germany
Primary
Secondary
Venoocclusive Liver Disease Hospitalization 3/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Level Increased Hospitalization 2/1/2008 30 Male 3/18/2008 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Male 3/26/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Obliterative Bronchiolitis Other Serious 10 Female 3/26/2008 Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 12 Male 3/27/2008 Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/27/2008 Other Health Professional Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/31/2008 Other Health Professional Germany
Primary
Secondary
Sepsis Hospitalization 7/21/2006 54 Male 134 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Viral Infection Other Serious 11/30/2007 51 Female 106 lb 4/1/2008 Physician Belgium
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death Male 4/2/2008 Germany
Primary
Secondary
Vertigo Death 58 Male 3/29/2008 Physician Germany
Primary
Secondary
Venoocclusive Liver Disease Other Serious 4/7/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Viral Infection Other Serious 11/30/2007 51 Female 106 lb 4/7/2008 Physician Belgium
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 12 Male 4/7/2008 Japan
Primary
Concomitant
Vertigo Other Serious 58 Male 4/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Viral Infection Other Serious 11/30/2007 51 Female 106 lb 4/10/2008 Physician Belgium
Primary
Concomitant
Rash Death 5/1/2005 42 Female 4/3/2008 Other Health Professional Belgium
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 5 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Rhabdomyolysis Hospitalization 66 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis E Other Serious 1/1/2005 30 Female 4/17/2008 Netherlands
Primary
Secondary
Speech Disorder Death 45 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 44 Female 4/17/2008 Physician United States
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Other Serious 4/12/1999 30 Female 4/21/2008 Physician Netherlands
Primary
Secondary
Trismus Death 45 Male 4/21/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 44 Female 4/29/2008 Physician United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 26 Male 4/29/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 26 Male 5/2/2008 United States
Primary
Secondary
Concomitant
Surgical Procedure Repeated Hospitalization 40 Female 4/29/2008 Netherlands
Primary
Secondary
Concomitant
Urinary Incontinence Death 45 Male 5/1/2008 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 5/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious 5 Female 5/13/2008
Primary
Secondary
Concomitant
Vertigo Death Male 5/2/2008 Germany
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 4/3/2008 26 Male 5/14/2008 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Thrombotic Microangiopathy Other Serious 5/22/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Male 5/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Transfusion Microchimerism Other Serious 9 Female 6/6/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Pneumomediastinum Other Serious 1/1/2007 61 Male 6/13/2008 Other Health Professional Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 9 Female 6/13/2008 Germany
Primary
Secondary

Drug Data