Methylprednisolone combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cerebrovascular Accident Hospitalization 11/25/2005 62 Male 1/12/2006 Physician Belgium
Primary
Secondary
Concomitant
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 11/25/2005 62 Male 1/23/2006 Physician Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/20/2005 Female 9/22/2005 United States
Primary
Concomitant
Renal Failure Acute Other Serious 14 Male 1/13/2006 United States
Primary
Concomitant
Wound Infection Hospitalization 7/5/2005 65 Male 2/1/2006 Physician Spain
Primary
Secondary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 2/2/2006 Physician Spain
Primary
Secondary
Concomitant
Neurological Symptom Hospitalization 1/15/2006 39 Female 2/8/2006 Physician United Kingdom
Primary
Secondary
Liver Abscess Hospitalization 8/22/2005 53 Male 2/27/2006 Physician France
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Erythema Infectiosum Hospitalization 1/18/2006 52 Female 137 lb 3/16/2006 Physician Canada
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 5/10/2005 41 Male 3/23/2006 Physician France
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 1/16/2006 58 Female 3/31/2006 Physician Germany
Primary
Secondary
Concomitant
Toe Amputation Hospitalization 11/3/2005 67 Male 4/7/2006 Physician Germany
Primary
Secondary
Concomitant
Gastrointestinal Infection Hospitalization 2/28/2005 61 Male 4/11/2006 Physician Germany
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 26 Male 4/12/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/28/2005 66 Male 4/14/2006 Physician Spain
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 4/25/2006 Physician Germany
Primary
Secondary
Concomitant
Foot Amputation Hospitalization 10/31/2005 67 Male 4/28/2006 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Death 40 Female 115 lb 4/28/2006 Physician Japan
Primary
Concomitant
Urine Output Decreased Required Intervention 11/15/2005 64 Female 118 lb 1/3/2006 United States
Primary
Concomitant
Pyrexia Required Intervention 12/2/2005 60 Male 161 lb 12/29/2005 United States
Primary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 5/23/2006 Physician Germany
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 3/30/2006 65 Male 6/5/2006 Physician Sweden
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/17/2006 52 Female 137 lb 6/5/2006 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 6/19/2004 67 Male 6/9/2006 Physician Sweden
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 36 Male 6/12/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 5/10/2005 41 Male 6/15/2006 Physician France
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2005 65 Male 6/19/2006 Physician Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2005 65 Male 6/26/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 26 Male 7/6/2006 Physician United Kingdom
Primary
Concomitant
Urethral Haemorrhage Other Serious 1/1/2000 39 Male 7/20/2006 Other Health Professional Finland
Primary
Secondary
Respiratory Depression Life Threatening 2/25/2005 44 Female 7/24/2006 Physician Germany
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 3/23/2005 26 Male 7/25/2006 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 1/16/2006 58 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/31/2005 45 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Splenic Rupture Death 39 Male 8/7/2006 Physician Finland
Primary
Secondary
Liver Disorder Other Serious 40 Male 8/12/2006 Japan
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 1/16/2006 58 Female 8/21/2006 Physician Germany
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 8/21/2005 47 Female 8/22/2006 Physician France
Primary
Secondary
Concomitant
Liver Disorder Other Serious 40 Male 8/22/2006 Japan
Primary
Secondary
Concomitant
Wound Drainage Hospitalization 8/20/2006 69 Male 200 lb 8/22/2006 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/16/2006 58 Female 9/5/2006 Physician Germany
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 9/8/2006 55 Male 192 lb 9/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 8/21/2005 59 Female 9/29/2006 Physician Germany
Primary
Secondary
Concomitant
Liver Abscess Hospitalization 8/22/2005 53 Male 10/3/2006 Physician France
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/12/2006 33 Male 10/5/2006 Japan
Primary
Secondary
Concomitant
Staphylococcal Abscess Hospitalization 8/22/2005 53 Male 10/9/2006 Physician France
Primary
Secondary
Concomitant
Trichosporon Infection Death 42 Male 10/9/2006 Japan
Primary
Secondary
Concomitant
Rash Other Serious 4/28/2005 1 Male 10/10/2006 Physician Spain
Primary
Concomitant
Hepatitis C Hospitalization 4/24/2005 65 Male 10/11/2006 Physician France
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/12/2006 33 Male 10/12/2006 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/12/2006 33 Male 10/12/2006 Japan
Primary
Secondary
Concomitant
Melaena Other Serious 1/1/2004 41 Female 10/17/2006 Japan
Primary
Secondary
Concomitant
Trichosporon Infection Death 42 Male 10/17/2006 Japan
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 11/13/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 1/16/2006 43 Male 11/15/2006 Physician France
Primary
Secondary
Concomitant
Kaposi's Sarcoma Other Serious 6/1/2006 44 Male 11/17/2006 Physician France
Primary
Secondary
Concomitant
Deep Vein Thrombosis Disability 8/9/2005 72 Female 11/27/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/4/2005 61 Male 11/24/2006 Physician Belgium
Primary
Secondary
Concomitant
Deep Vein Thrombosis Disability 8/9/2005 72 Female 11/29/2006 Physician Japan
Primary
Secondary
Concomitant
Deep Vein Thrombosis Disability 8/9/2005 72 Female 2/2/2007 Physician Japan
Primary
Secondary
Concomitant
Shock Life Threatening 12/17/2005 24 Male 3/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 5/12/2006 69 Male 3/19/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Life Threatening 5/10/2006 62 Male 3/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Disability 8/9/2005 72 Female 4/6/2007 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/7/2005 64 Male 3/21/2007 Physician Switzerland
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 10/20/2004 67 Male 4/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/1/2005 49 Female 4/24/2007 Other Health Professional Belgium
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 4/13/2005 59 Male 4/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 11/25/2005 62 Male 4/25/2007 Other Health Professional Belgium
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/20/2006 53 Female 5/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/1/2005 49 Female 5/3/2007 Other Health Professional Belgium
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/7/2005 64 Male 5/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/1/2005 49 Female 5/12/2007 Other Health Professional Belgium
Primary
Secondary
Concomitant
Hepatorenal Syndrome Other Serious 8/4/2004 46 Female 5/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Surgical Procedure Repeated Life Threatening 6/30/2005 58 Male 5/23/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 5/24/2007 Physician France
Primary
Secondary
Concomitant
Surgical Procedure Repeated Life Threatening 7/14/2004 53 Male 6/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 4/13/2005 59 Male 6/6/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/21/2006 85 Female 84 lb 6/18/2007 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 7/11/2005 52 Female 6/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/30/2005 58 Male 6/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 6/25/2004 59 Male 4/4/2007 Physician Sweden
Primary
Secondary
Concomitant
Epilepsy Hospitalization 11/27/2004 44 Female 3/30/2007 Physician Belgium
Primary
Secondary
Concomitant
Virus Urine Test Positive Hospitalization 31 Male 6/30/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 6/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/7/2007 Female 99 lb 7/3/2007 Physician Japan
Primary
Concomitant
Systemic Inflammatory Response Syndrome Death 7/6/2005 64 Male 6/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Encephalopathy Other Serious 13 Male 7/13/2007 Japan
Primary
Secondary
Myocardial Infarction Hospitalization 7/13/2006 85 Female 84 lb 7/6/2007 Physician Japan
Primary
Concomitant
Subcutaneous Abscess Hospitalization 39 Male 7/18/2007 Japan
Primary
Secondary
Wound Infection Staphylococcal Other Serious 39 Male 7/31/2007 Japan
Primary
Secondary
Thrombocytopenia Life Threatening 6/4/2007 31 Female 139 lb 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
Linear Iga Disease Other Serious 65 Male 8/29/2007 Other Health Professional Austria
Primary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 5 Male 40 lb 9/18/2007
Primary
Secondary
Transplant Rejection Other Serious 9/20/2007 Physician Germany
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/20/2006 68 Female 154 lb 9/13/2007 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 5 Male 39 lb 9/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 5/26/2005 Male 192 lb 9/24/2007 Physician United Kingdom
Primary
Concomitant
Stem Cell Transplant Hospitalization 7/28/2007 Male 9/20/2007 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 52 Male 9/26/2007 Other Health Professional Belgium
Primary
Secondary
Transplant Rejection Hospitalization 5/26/2005 Male 192 lb 9/26/2007 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 31 Female 139 lb 9/18/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/1/1998 26 Male 146 lb 10/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 Male 9/28/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/11/2007 58 Male 176 lb 9/20/2007 Pharmacist United States
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/8/2007 Other Health Professional Malaysia
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/12/2007 Other Health Professional Malaysia
Primary
Concomitant
Pleural Effusion Required Intervention 6/25/2007 44 Female 86 lb 7/30/2007 United States
Primary
Concomitant
Transitional Cell Carcinoma Other Serious 12 Male 10/17/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Sepsis Other Serious 58 Female 10/30/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 8/16/1996 53 Female 96 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Liver And Pancreas Transplant Rejection Other Serious 10/14/2007 1 Male 23 lb 10/26/2007 Pharmacist Canada
Primary
Concomitant
Renal Artery Stenosis Hospitalization 10/24/2003 34 Male 161 lb 11/9/2007 Physician Germany
Primary
Secondary
Concomitant
Neuropathy Other Serious 52 Male 11/12/2007 Physician Belgium
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 34 Male 117 lb 11/13/2007 India
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 1 Female 11/14/2007
Primary
Secondary
Concomitant
Neuropathy Other Serious 52 Male 11/19/2007 Physician Belgium
Primary
Concomitant
Thyroiditis Other Serious 50 Male 11/26/2007 Other Health Professional Saudi Arabia
Primary
Secondary
Pseudomonas Infection Required Intervention 9/27/2007 39 Male 154 lb 11/1/2007 Pharmacist United States
Primary
Concomitant
Transaminases Increased Hospitalization 11 Male 12/3/2007 Japan
Primary
Secondary
Wound Dehiscence Hospitalization 52 Male 12/3/2007 Belgium
Primary
Secondary
Retinal Detachment Hospitalization 1/1/2006 68 Female 12/4/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 54 Female 12/10/2007 United States
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 5/1/2006 59 Female 12/10/2007 United States
Primary
Secondary
Weight Decreased Other Serious 12/1/2005 55 Male 12/10/2007 United States
Primary
Secondary
Sepsis Hospitalization 70 Male 12/18/2007 Spain
Primary
Secondary
Platelet Count Decreased Life Threatening 11/6/2007 Female 115 lb 11/15/2007 Pharmacist United States
Primary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/12/2005 62 Male 192 lb 1/17/2008 Physician United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Life Threatening 23 Female 1/17/2008 Other Health Professional Greece
Primary
Secondary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/12/2005 62 Male 192 lb 2/7/2008 Physician United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 5/12/2006 45 Female 159 lb 2/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vesicoureteric Reflux Other Serious 9 Male 2/15/2008 Other Health Professional Japan
Primary
Concomitant
Liver Abscess Hospitalization 8/1/2005 18 Female 2/14/2008 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 9 Female 2/18/2008 Physician Australia
Primary
Concomitant
Protein Total Decreased Other Serious 12 Female 3/1/2008 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Life Threatening 2/12/2008 69 Female 117 lb 2/26/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Serositis Death 1 3/6/2008 Consumer Japan
Primary
Concomitant
Kaposi's Sarcoma Other Serious 65 3/6/2008 Other Health Professional Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/7/2008 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/7/2008 Physician Belgium
Primary
Concomitant

Drug Data