Allopurinol combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Syncytial Virus Infection Other Serious 12/16/2005 Male 160 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/1/2006 60 Male 2/17/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/1/2006 60 Male 3/9/2006 Consumer United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 4/25/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 5/23/2006 Physician Germany
Primary
Secondary
Concomitant
Urticaria Generalised Other Serious 1/25/2006 71 Female 219 lb 6/5/2006 Physician Canada
Primary
Concomitant
Tremor Hospitalization 1/16/2006 57 Male 206 lb 5/4/2006 United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 2/25/2006 68 Male 9/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2006 38 Male 11/3/2006 Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 9/5/2006 72 Female 12/6/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 7/20/2006 50 Female 119 lb 3/19/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 7/22/2006 80 Male 136 lb 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Life Threatening 1/1/2006 Male 159 lb 4/16/2007 Physician Germany
Primary
Concomitant
Transplant Failure Life Threatening 3/30/2006 Male 159 lb 6/26/2007 Physician Germany
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 12/1/2005 66 Male 243 lb 1/15/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 6/8/2007 Male 107 lb 6/11/2007 Pharmacist United States
Primary
Concomitant
Transplant Rejection Other Serious 8/1/2006 51 Male 9/4/2007 Physician Czech Republic
Primary
Secondary
Concomitant
Multiple Myeloma Hospitalization 5/4/2006 67 Male 172 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 1/1/2006 68 Female 12/4/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Transplant Failure Life Threatening 3/30/2006 Male 159 lb 12/12/2007 Physician Germany
Primary
Concomitant
Ventricular Dysfunction Life Threatening 11/3/2007 16 Female 208 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 2/1/2008 30 Male 3/18/2008 Physician France
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 1/17/2003 68 Male 3/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/3/2007 16 Female 208 lb 4/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Human Polyomavirus Infection Other Serious 5/19/2004 Male 183 lb 4/17/2008 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/11/2007 31 Female 139 lb 4/28/2008 Physician Japan
Primary
Secondary
Concomitant
Chest Pain Life Threatening 5/8/2008 63 Male 5/14/2008 Sweden
Primary
Concomitant
Persecutory Delusion Hospitalization 2/24/2008 62 Male 5/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Impaired Work Ability Life Threatening 2/1/2008 63 Male 128 lb 6/5/2008 Sweden
Primary
Concomitant
Graft Versus Host Disease Hospitalization 5/12/2008 60 Female 234 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 5/12/2008 60 Female 200 lb 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/10/2006 Male 174 lb 7/5/2008 Physician United States
Primary
Secondary
Stem Cell Transplant Hospitalization 5/12/2008 60 Female 200 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 Male 7/25/2008 Physician Japan
Primary
Concomitant
Angiosarcoma Life Threatening 4/1/2008 68 Male 8/4/2008 Physician Germany
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 5/29/2007 36 Female 8/4/2008 Physician United States
Primary
Secondary
Concomitant
Angiosarcoma Life Threatening 4/1/2008 68 Male 8/6/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 9/10/2006 Male 174 lb 8/7/2008 Physician United States
Primary
Secondary
Cardiac Failure Life Threatening 8/3/2008 63 Male 8/8/2008 Sweden
Primary
Concomitant
Presyncope Other Serious 6/1/2008 63 Male 131 lb 8/11/2008 Sweden
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 8/16/2008 68 Male 8/27/2008 Physician United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/2/2008 68 Male 8/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Hospitalization 8/16/2008 68 Male 9/24/2008 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 8/16/2008 68 Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 9/15/2008 Male 234 lb 11/3/2008 Pharmacist United States
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 2/3/2009 Male 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 1/13/2009 51 Male 198 lb 4/24/2009 Physician Canada
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 1/13/2009 51 Male 198 lb 4/28/2009 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 73 Male 287 lb 5/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 10/9/2007 Male 5/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 5/17/2005 29 Female 5/7/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Serum Sickness Other Serious 4/30/2007 24 Female 194 lb 5/28/2009 Physician United States
Primary
Concomitant
Human Polyomavirus Infection Other Serious 5/19/2004 Male 183 lb 6/23/2009 Physician Spain
Primary
Secondary
Concomitant
Leiomyosarcoma Hospitalization 3/16/2005 Male 194 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 11/26/2003 Female 133 lb 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 12/3/2007 Male 7/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 1/13/2009 51 Male 198 lb 7/15/2009 Physician Canada
Primary
Concomitant
Postictal State Other Serious 4/13/2009 54 Male 215 lb 7/24/2009 Consumer United States
Primary
Concomitant
Leiomyosarcoma Hospitalization 3/16/2005 72 Male 8/13/2009 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/30/2009 Female 8/27/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Liver Injury Hospitalization 4/22/2009 47 Male 201 lb 9/10/2009 Physician Germany
Primary
Concomitant
Liver Injury Hospitalization 1/1/2009 47 Male 201 lb 9/15/2009 Physician Germany
Primary
Concomitant
Liver Injury Hospitalization 4/17/2009 47 Male 201 lb 9/17/2009 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 6/30/2009 55 Female 9/14/2009 United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 6/14/2009 45 Male 249 lb 6/16/2009 Pharmacist United States
Primary
Concomitant
Drug Toxicity Other Serious 9/9/2008 58 Female 137 lb 10/15/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Hypertension Other Serious 9/9/2008 58 Female 137 lb 10/21/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Application Site Cellulitis Hospitalization 11/8/2009 Male 171 lb 11/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 1/1/2009 Male 155 lb 12/4/2009 Physician Germany
Primary
Concomitant
Transplant Failure Other Serious 1/1/2009 Male 155 lb 12/14/2009 Physician Germany
Primary
Concomitant
Transplant Failure Other Serious 1/1/2009 Male 155 lb 12/29/2009 Physician Germany
Primary
Concomitant
Stress Other Serious 10/11/2007 56 Female 98 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/11/2007 56 Female 98 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Hospitalization 10/28/2009 Male 171 lb 3/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombosis Hospitalization 10/28/2009 Male 3/31/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis Hospitalization 10/28/2009 62 Male 4/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis Hospitalization 10/28/2009 62 Male 171 lb 4/6/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombosis Hospitalization 10/29/2009 62 Male 171 lb 4/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 5/4/2010 56 Male 234 lb 5/24/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/4/2010 56 Male 234 lb 6/4/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 5/4/2010 56 Male 234 lb 6/7/2010 Physician United States
Primary
Concomitant
Overdose Other Serious 12/11/2008 48 Male 6/10/2010 Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 4/18/2010 48 Female 6/21/2010 Pharmacist Japan
Primary
Concomitant
Respiratory Failure Hospitalization 5/8/2010 72 Male 6/24/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 5/8/2010 72 Male 7/1/2010 Physician Japan
Primary
Concomitant
Ileus Hospitalization 4/18/2010 48 Female 7/2/2010 Pharmacist Japan
Primary
Concomitant
Respiratory Failure Hospitalization 5/8/2010 72 Male 8/31/2010 Physician Japan
Primary
Concomitant
Kidney Transplant Rejection Death 56 Male 8/31/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Septic Shock Other Serious 5/8/2010 72 Male 9/20/2010 Physician Japan
Primary
Concomitant
Transplant Failure Other Serious 4/14/2006 44 Male 9/14/2010 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 6/30/2010 56 Male 184 lb 9/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 10/21/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Other Serious 5/8/2010 72 Male 10/27/2010 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 5/8/2010 72 Male 11/5/2010 Physician Japan
Primary
Concomitant
Pancreatitis Other Serious 4/14/2006 44 Male 11/5/2010 Physician Japan
Primary
Secondary
Concomitant
Transplant Failure Other Serious 4/14/2006 44 Male 11/16/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 5/8/2010 72 Male 12/15/2010 Physician Japan
Primary
Concomitant
Lung Adenocarcinoma Other Serious 8/5/2009 64 Male 137 lb 12/1/2010 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Hospitalization 11/20/2009 41 Male 126 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Death 35 Male 153 lb 1/7/2011 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Death 35 Male 177 lb 1/24/2011 Pharmacist United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Hospitalization 9/30/2009 18 Female 137 lb 1/28/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 3/12/2010 2 Male 22 lb 3/9/2011 Physician Japan
Primary
Concomitant
Hypertonia Disability 1/21/2011 Male 11 lb 3/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertonia Disability 1/21/2011 0 Male 11 lb 3/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypertonia Disability 1/21/2011 0 Male 11 lb 3/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Convulsion Disability 1/21/2011 0 Male 3/15/2011 Physician Denmark
Primary
Secondary
Concomitant
Pulmonary Granuloma Other Serious 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Blood Creatinine Increased Hospitalization 12/31/2010 65 Male 165 lb 3/23/2011 Pharmacist United States
Primary
Concomitant
Stem Cell Transplant Death 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/1/2010 71 Female 154 lb 3/29/2011 Consumer Spain
Primary
Concomitant
Colitis Hospitalization 1/27/2011 68 Male 201 lb 4/13/2011 Consumer India
Primary
Concomitant
Venoocclusive Liver Disease Death 35 Male 177 lb 4/21/2011 Pharmacist United States
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 5/17/2006 56 Male 159 lb 5/16/2011 Physician Germany
Primary
Concomitant
Cytomegalovirus Infection Disability 10/14/2005 8 Male 55 lb 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 7/25/2009 70 Male 5/31/2011 Pharmacist United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 2/28/2011 70 Male 229 lb 6/3/2011 Other Health Professional United States
Primary
Concomitant
Drug Level Increased Hospitalization 7/13/2009 65 Male 176 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 60 Male 6/16/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Serum Sickness Death 7/16/2010 68 Male 121 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Skin Other Serious 60 Male 6/17/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Hepatic Failure Death 8/30/2002 6 Male 35 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Eating Disorder Other Serious 9/1/2010 26 Female 121 lb 7/7/2011 Physician Japan
Primary
Concomitant
Neutropenic Sepsis Hospitalization 9/16/2010 59 Male 174 lb 7/8/2011 Physician Belgium
Primary
Secondary
Concomitant
Drug Interaction Other Serious 62 Male 7/13/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Muscle Enzyme Increased Other Serious 62 Male 7/14/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Hyperuricaemia Hospitalization 2/7/2008 38 Male 7/7/2011 Physician Japan
Primary
Secondary
Concomitant
Discomfort Death 7/19/2011 60 Male 7/21/2011 Consumer United States
Primary
Concomitant
Interacting
Anhedonia Other Serious Male 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 3/1/2011 59 Female 8/9/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2010 59 Male 174 lb 9/9/2011 Physician Belgium
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 4/23/2008 48 Male 138 lb 9/12/2011 Physician Japan
Primary
Secondary
Concomitant
Induration Other Serious 3/1/2007 67 Female 230 lb 9/27/2011 Physician United States
Primary
Secondary
Concomitant
Arthralgia Other Serious 4/1/2005 50 Male 170 lb 9/27/2011 Consumer United States
Primary
Secondary
Concomitant
Fatigue Death 12/30/2008 70 Male 9/30/2011 Physician United States
Primary
Concomitant
Periorbital Oedema Life Threatening 1/27/2011 6 Female 40 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 12/7/2010 6 Female 40 lb 10/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 6 Female 40 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Disease Recurrence Other Serious 3/28/2008 42 Female 10/7/2011 Japan
Primary
Concomitant
Pancreatic Enzymes Increased Hospitalization 8/9/2011 50 Male 10/13/2011 Other Health Professional France
Primary
Secondary
Concomitant

Drug Data