Rapamune combined with Tacrolimus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Tubular Atrophy Hospitalization 4/3/2005 63 Male 2/1/2006 Germany
Primary
Concomitant
Scedosporium Infection Hospitalization 8/1/2005 56 Male 3/13/2006 Physician Australia
Primary
Secondary
Concomitant
Dehydration Other Serious 11/10/2004 55 Female 167 lb 3/13/2006 United States
Primary
Concomitant
Vomiting Life Threatening 3/5/2006 64 Female 4/14/2006 Spain
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/2005 51 Female 4/7/2006 Physician France
Primary
Concomitant
Vomiting Life Threatening 3/3/2006 64 Female 6/13/2006 Spain
Primary
Concomitant
Renal Failure Other Serious 7/26/2005 52 Female 7/24/2006 United Kingdom
Primary
Secondary
Concomitant
Dilatation Intrahepatic Duct Acquired Other Serious 7/5/2006 59 Male 10/17/2006 United Kingdom
Primary
Concomitant
Osteoporosis Other Serious 4/1/2005 46 Male 10/17/2006 United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/14/2005 39 Male 11/2/2006 United States
Primary
Secondary
Concomitant
Liver Abscess Other Serious 7/5/2006 59 Male 11/21/2006 United Kingdom
Primary
Concomitant
Hypertension Life Threatening 3/5/2006 Female 211 lb 2/26/2007 Physician Spain
Primary
Concomitant
Hypertension Life Threatening 3/5/2006 Female 211 lb 2/27/2007 Physician Spain
Primary
Concomitant
Hypertension Hospitalization 11/12/2004 Female 3/9/2007 Physician United States
Primary
Secondary
Premature Baby Other Serious Female 3/16/2007 Physician United States
Primary
Secondary
Concomitant
Premature Baby Other Serious Female 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Transplant Failure Life Threatening 1/1/2006 Male 159 lb 4/16/2007 Physician Germany
Primary
Concomitant
Hypertension Hospitalization 11/12/2004 Female 122 lb 4/18/2007 Physician United States
Primary
Secondary
Concomitant
Transplant Failure Life Threatening 3/30/2006 Male 159 lb 6/26/2007 Physician Germany
Primary
Concomitant
Pulmonary Embolism Life Threatening 3/15/2007 Male 223 lb 7/2/2007 Physician United States
Primary
Secondary
Transplant Rejection Other Serious 9/20/2007 Physician Germany
Primary
Concomitant
Complications Of Transplanted Kidney Hospitalization 11/8/2004 Male 9/25/2007 Physician Canada
Primary
Concomitant
Rhabdomyolysis Other Serious 4/6/2007 Male 123 lb 10/3/2007 Physician Spain
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 1/1/2004 Female 10/22/2007 Physician United States
Primary
Secondary
Transplant Failure Life Threatening 3/30/2006 Male 159 lb 12/12/2007 Physician Germany
Primary
Concomitant
Lymphocele Hospitalization 4/3/2005 Male 1/11/2008 Physician Germany
Primary
Concomitant
Transplant Rejection Hospitalization 10/12/2006 Female 143 lb 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/9/2005 Male 127 lb 1/17/2008 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/13/2007 Male 123 lb 1/17/2008 Physician Spain
Primary
Concomitant
Interacting
Type 2 Diabetes Mellitus Hospitalization 1/30/2005 Male 131 lb 1/17/2008 Physician United States
Primary
Secondary
Drug Toxicity Other Serious 2/10/2005 Female 108 lb 1/22/2008 Physician United States
Primary
Secondary
Multi-organ Failure Life Threatening 1/1/2007 58 Male 265 lb 2/28/2008 Other Health Professional Belgium
Primary
Concomitant
Renal Failure Acute Hospitalization 2/11/2008 Male 154 lb 3/17/2008 Physician Germany
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Other Serious 3/1/2005 64 Female 4/17/2008 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 4/3/2008 26 Male 5/14/2008 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Toxic Epidermal Necrolysis Hospitalization 4/25/2008 60 Male 5/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Serositis Hospitalization 12/15/2007 Female 104 lb 5/9/2008 United States
Primary
Secondary
Concomitant
Lobar Pneumonia Other Serious 1/1/2008 Female 110 lb 6/9/2008 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 3/25/2008 60 Male 6/3/2008 Physician United States
Primary
Secondary
Concomitant
Lobar Pneumonia Other Serious 1/1/2008 Female 110 lb 6/13/2008 Physician United States
Primary
Concomitant
Premature Baby Other Serious 3 lb 7/7/2008 Other Health Professional United States
Primary
Secondary
Death Death Female 143 lb 7/10/2008 Physician Bulgaria
Primary
Concomitant
Renal Failure Chronic Other Serious Female 143 lb 7/17/2008 Physician Bulgaria
Primary
Concomitant
Premature Baby Other Serious 3 lb 7/29/2008 Other Health Professional United States
Primary
Secondary
Platelet Count Decreased Hospitalization Male 231 lb 9/15/2008 Physician Sweden
Primary
Concomitant
Urinary Fistula Other Serious 9/11/2008 Male 165 lb 10/3/2008 Physician Brazil
Primary
Concomitant
Urinary Fistula Hospitalization 9/28/2008 Female 120 lb 10/9/2008 Physician Brazil
Primary
Concomitant
Skin Ulcer Hospitalization 9/3/2008 Male 185 lb 10/10/2008 Physician Germany
Primary
Concomitant
Urinary Fistula Hospitalization 9/28/2008 Female 120 lb 10/21/2008 Physician Brazil
Primary
Concomitant
Haemolysis Other Serious 27 Male 10/21/2008 Other Health Professional Australia
Primary
Concomitant
Urinary Fistula Other Serious 9/11/2008 Male 165 lb 10/22/2008 Physician Brazil
Primary
Concomitant
Soft Tissue Infection Other Serious 2/10/2004 40 Female 157 lb 10/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Soft Tissue Infection Other Serious 2/17/2004 40 Female 157 lb 10/27/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 2/21/2008 Male 231 lb 10/27/2008 Physician Sweden
Primary
Secondary
Soft Tissue Infection Other Serious 2/17/2004 40 Female 157 lb 10/29/2008 Physician United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 10/21/2008 Male 228 lb 10/30/2008 Physician Canada
Primary
Concomitant
Transplant Rejection Other Serious 10/21/2008 Male 228 lb 11/4/2008 Physician Canada
Primary
Concomitant
Urinary Fistula Other Serious 10/26/2008 Male 158 lb 11/10/2008 Physician Brazil
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 2/21/2008 Male 231 lb 11/13/2008 Physician Sweden
Primary
Secondary
Thrombotic Microangiopathy Hospitalization 7/18/2008 Male 198 lb 11/13/2008 Physician Sweden
Primary
Concomitant
Urinary Fistula Other Serious 10/26/2008 Male 158 lb 11/19/2008 Physician Brazil
Primary
Concomitant
Respiratory Rate Decreased Required Intervention 7/16/2008 72 Male 159 lb 8/1/2008 Pharmacist United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 10/22/2008 60 Male 11/24/2008 Physician Spain
Primary
Concomitant
Transplant Rejection Other Serious 10/21/2008 Male 228 lb 12/3/2008 Physician Canada
Primary
Concomitant
Pruritus Hospitalization 9/15/2008 Male 187 lb 12/19/2008 Physician Germany
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/23/2008 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 9/3/2008 Male 185 lb 1/28/2009 Physician Germany
Primary
Concomitant
Hepatic Neoplasm Malignant Recurrent Other Serious 7/18/2007 Male 1/29/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/23/2009 Female 25 lb 3/25/2009 United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/20/2009 Male 194 lb 4/9/2009 Physician Canada
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 4/21/2009 United States
Primary
Secondary
Diabetes Mellitus Other Serious 4/21/2009 United States
Primary
Secondary
Diabetes Mellitus Other Serious 4/21/2009 United States
Primary
Secondary
Diabetes Mellitus Other Serious 4/21/2009 United States
Primary
Secondary
Diabetes Mellitus Other Serious 4/21/2009 United States
Primary
Secondary
Treatment Noncompliance Life Threatening 1/4/2009 Male 125 lb 1/7/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/11/2008 Male 154 lb 5/15/2009 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/13/2007 Male 123 lb 5/18/2009 Physician Spain
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 2/11/2008 Male 154 lb 5/22/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/13/2009 Male 155 lb 6/17/2009 Physician Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/13/2007 Male 123 lb 6/19/2009 Physician Spain
Primary
Concomitant
Interacting
Stomatitis Necrotising Hospitalization 2/2/2004 Female 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/19/2004 Female 6/25/2009 Physician Spain
Primary
Secondary
Concomitant
Ureteric Obstruction Hospitalization 12/3/2003 Female 6/30/2009 Physician Sweden
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/1/2004 Male 6/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/18/2004 Female 6/30/2009 Physician Sweden
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 7/2/2007 Male 123 lb 7/29/2009 Physician Spain
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 7/2/2007 Male 123 lb 8/5/2009 Physician Spain
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 7/2/2007 Male 123 lb 8/6/2009 Physician Spain
Primary
Concomitant
Interacting
Tumour Excision Other Serious 1/1/2006 38 Female 8/7/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pharyngitis Hospitalization 8/18/2009 Male 180 lb 8/26/2009 Physician Canada
Primary
Secondary
Concomitant
Pharyngitis Hospitalization 8/18/2009 Male 180 lb 8/28/2009 Physician Canada
Primary
Secondary
Concomitant
Skin Burning Sensation Hospitalization 1/1/2008 37 Male 9/1/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Pharyngitis Hospitalization 8/17/2009 Male 180 lb 9/8/2009 Physician Canada
Primary
Secondary
Concomitant
Pharyngitis Hospitalization 8/17/2009 Male 180 lb 9/14/2009 Physician Canada
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 30 Male 9/24/2009 Physician United States
Primary
Concomitant
Transplant Failure Other Serious 62 Female 9/24/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 9/21/2009 Male 137 lb 9/24/2009 United States
Primary
Secondary
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 10/6/2006 50 Male 148 lb 10/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/31/2009 74 Female 11/16/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Venoocclusive Disease Death 18 Male 12/7/2009 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 18 Female 12/7/2009 Physician United States
Primary
Concomitant
Venoocclusive Disease Death 11 Male 12/7/2009 Physician United States
Primary
Concomitant
Venoocclusive Disease Death 7 Male 12/7/2009 Physician United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 10 Female 12/7/2009 Physician United States
Primary
Concomitant
Pleural Effusion Other Serious 10 Male 12/7/2009 Physician United States
Primary
Concomitant
Venoocclusive Disease Death 1 Female 12/7/2009 Physician United States
Primary
Concomitant

Drug Data