Vincristine



Indications and Reactions:

Role Indications Reactions
Primary
Acute Lymphocytic Leukaemia 31.0%
Non-hodgkin's Lymphoma 19.5%
Diffuse Large B-cell Lymphoma 8.1%
B-cell Lymphoma 6.9%
Lymphoma 6.2%
Hodgkin's Disease 4.0%
Product Used For Unknown Indication 3.4%
Ewing's Sarcoma 3.2%
Chronic Lymphocytic Leukaemia 2.2%
Multiple Myeloma 2.0%
B Precursor Type Acute Leukaemia 1.9%
Neoplasm Malignant 1.5%
Non-hodgkin's Lymphoma Stage Iii 1.5%
Lymphocytic Leukaemia 1.4%
Diffuse Large B-cell Lymphoma Stage Iii 1.3%
T-cell Type Acute Leukaemia 1.3%
Burkitt's Lymphoma 1.2%
Burkitt's Lymphoma Stage Iii 1.2%
Peripheral T-cell Lymphoma Unspecified 1.1%
Acute Myeloid Leukaemia 1.0%
Stem Cell Transplant 15.7%
Sepsis 9.1%
Cytogenetic Abnormality 8.7%
Leukoencephalopathy 7.0%
Neutropenia 6.5%
Thrombocytopenia 6.1%
Reversible Posterior Leukoencephalopathy Syndrome 4.8%
Encephalopathy 4.3%
Febrile Neutropenia 4.3%
Neuropathy Peripheral 3.9%
Pancytopenia 3.9%
Pyrexia 3.9%
Posterior Reversible Encephalopathy Syndrome 3.5%
Pulmonary Embolism 3.0%
Septic Shock 3.0%
Staphylococcal Infection 3.0%
Acute Myeloid Leukaemia 2.6%
Neurotoxicity 2.2%
Progressive Multifocal Leukoencephalopathy 2.2%
Respiratory Failure 2.2%
Secondary
Diffuse Large B-cell Lymphoma 28.1%
Acute Lymphocytic Leukaemia 12.0%
Drug Use For Unknown Indication 9.2%
B-cell Lymphoma 8.0%
Non-hodgkin's Lymphoma 7.4%
Product Used For Unknown Indication 7.0%
Hodgkin's Disease 4.9%
Mantle Cell Lymphoma 3.7%
Burkitt's Lymphoma 3.7%
Prophylaxis 2.7%
Lymphoma 2.6%
Peripheral T-cell Lymphoma Unspecified 1.6%
T-cell Lymphoma 1.5%
Sarcoma 1.4%
Rhabdomyosarcoma 1.1%
Ewing's Sarcoma 1.1%
Chemotherapy 1.1%
Chronic Lymphocytic Leukaemia 1.0%
Multiple Myeloma 1.0%
Burkitt's Leukaemia 0.9%
Febrile Neutropenia 15.9%
Death 7.0%
Neutropenia 6.9%
Sepsis 6.7%
Thrombocytopenia 6.3%
Infection 5.8%
Pyrexia 5.3%
Pneumonia 5.1%
Vomiting 4.7%
Off Label Use 4.3%
White Blood Cell Count Decreased 4.2%
Toxicity To Various Agents 4.1%
Myelodysplastic Syndrome 3.8%
Pneumocystis Jiroveci Pneumonia 3.7%
Pulmonary Embolism 3.2%
Weight Decreased 2.9%
Septic Shock 2.7%
Respiratory Failure 2.6%
Thrombosis 2.5%
Hepatitis B 2.4%
Concomitant
Drug Use For Unknown Indication 13.7%
Diffuse Large B-cell Lymphoma 12.3%
Non-hodgkin's Lymphoma 11.1%
Acute Lymphocytic Leukaemia 9.6%
Product Used For Unknown Indication 9.2%
B-cell Lymphoma 8.1%
Multiple Myeloma 7.4%
Lymphoma 6.9%
Chemotherapy 5.2%
Prophylaxis 2.9%
Chronic Lymphocytic Leukaemia 2.0%
Idiopathic Thrombocytopenic Purpura 1.9%
Mantle Cell Lymphoma 1.7%
Pain 1.6%
Hypertension 1.3%
Hodgkin's Disease 1.3%
Burkitt's Lymphoma 1.2%
Premedication 0.9%
T-cell Lymphoma 0.9%
Malignant Lymphoid Neoplasm 0.7%
Vomiting 9.4%
Progressive Multifocal Leukoencephalopathy 8.3%
Febrile Neutropenia 8.1%
Sepsis 7.8%
Thrombocytopenia 6.6%
Weight Decreased 6.5%
Pyrexia 6.3%
White Blood Cell Count Decreased 5.8%
Death 5.7%
Neutropenia 5.7%
Pneumocystis Jiroveci Pneumonia 4.0%
Respiratory Failure 3.9%
Wound Drainage 3.6%
Renal Failure 3.4%
Septic Shock 3.0%
White Blood Cell Count Increased 2.6%
Pneumonia 2.5%
Pleural Effusion 2.4%
Pulmonary Fibrosis 2.3%
Drug Ineffective 2.3%
Interacting
Acute Lymphocytic Leukaemia 16.9%
Non-hodgkin's Lymphoma Unspecified Histology Aggressive 11.7%
Non-hodgkin's Lymphoma 9.8%
Ewing's Sarcoma 9.1%
Product Used For Unknown Indication 8.5%
Diffuse Large B-cell Lymphoma 7.2%
Prophylaxis 6.8%
B-cell Lymphoma 4.6%
Drug Use For Unknown Indication 3.3%
Lymphoma 3.3%
Bone Sarcoma 2.9%
Retinoblastoma 2.6%
Febrile Neutropenia 2.3%
Brain Neoplasm 2.0%
Fungal Infection 2.0%
Burkitt's Lymphoma 1.6%
Chronic Lymphocytic Leukaemia 1.6%
Gastritis 1.3%
Oral Candidiasis 1.3%
Precursor T-lymphoblastic Lymphoma/leukaemia 1.3%
Drug Interaction 31.8%
Neuropathy Peripheral 14.1%
Ileus Paralytic 10.6%
Neurotoxicity 10.6%
Muscular Weakness 4.7%
Renal Impairment 3.5%
Agranulocytosis 2.4%
Apnoea 2.4%
Autonomic Neuropathy 2.4%
Leukopenia 2.4%
Neutropenia 2.4%
Ocular Vascular Disorder 2.4%
Weight Decreased 2.4%
Anaphylactic Reaction 1.2%
Angioedema 1.2%
Bladder Cancer 1.2%
Constipation 1.2%
Fat Embolism 1.2%
Hyponatraemia 1.2%
Ileus 1.2%