Mercaptopurine combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Malaise Hospitalization 10/15/2005 4 Female 1/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Necrotising Hospitalization 9/30/2005 7 Female 53 lb 1/23/2006 United States
Primary
Concomitant
Respiratory Disorder Other Serious 17 Male 2/2/2006 Other Health Professional Ireland
Primary
Secondary
Pseudobulbar Palsy Other Serious 17 Male 2/3/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 10/15/2005 4 Female 2/14/2006 France
Primary
Secondary
Concomitant
Tongue Paralysis Life Threatening 17 Male 2/15/2006
Primary
Secondary
Pseudobulbar Palsy Other Serious 17 Male 3/1/2006 Physician Ireland
Primary
Concomitant
Urinary Incontinence Disability 18 Male 3/15/2006
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 48 Female 3/15/2006
Primary
Concomitant
Sepsis Other Serious 15 Male 3/17/2006 United States
Primary
Secondary
Concomitant
Polyuria Other Serious 13 Female 3/17/2006 United States
Primary
Concomitant
Urinary Incontinence Hospitalization 3/1/1997 16 Male 5/1/2006 Physician Spain
Primary
Secondary
Thrombocytopenic Purpura Other Serious 16 Male 6/2/2006 Physician Canada
Primary
Secondary
Idiopathic Thrombocytopenic Purpura Other Serious 10 Female 6/3/2006 Physician Canada
Primary
Secondary
Metastasis Other Serious 3 Male 7/25/2006 Physician Turkey
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 13 Female 7/25/2006 Physician Turkey
Primary
Secondary
Primitive Neuroectodermal Tumour Death 10 Male 7/25/2006 Physician Turkey
Primary
Secondary
Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Staphylococcal Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Enterobacter Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Bacterial Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Blood Growth Hormone Decreased Other Serious 12 Female 8/4/2006 Other Health Professional United States
Primary
Secondary
Epiphyseal Disorder Other Serious 15 Male 8/4/2006 Other Health Professional United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 26 Female 8/16/2006 Physician United States
Primary
Secondary
Urinary Incontinence Required Intervention 16 Male 9/1/2006 Other Health Professional Spain
Primary
Concomitant
Urticaria Generalised Hospitalization 8/25/2006 Female 33 lb 9/1/2006 United States
Primary
Secondary
Vertigo Hospitalization 7/16/2006 57 Male 198 lb 9/5/2006 United Kingdom
Primary
Concomitant
Urinary Incontinence Required Intervention 1/1/1997 16 Male 9/20/2006 Other Health Professional Spain
Primary
Concomitant
Tremor Hospitalization 3 Male 10/12/2006
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 10/25/2004 7 Male 11/13/2006
Primary
Secondary
Thrombosis 9/29/2006 Pharmacist United States
Primary
Concomitant
Pancreatitis Other Serious 10/20/2006 17 Female 112 lb 12/18/2006 United Kingdom
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 7/4/2003 17 Female 10/7/2006 United States
Primary
Concomitant
Neurotoxicity Other Serious 13 Male 10/7/2006 United States
Primary
Concomitant
Hepatotoxicity Other Serious 52 Male 1/19/2007 Other Health Professional Israel
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 52 Male 1/18/2007 Physician Israel
Primary
Secondary
Concomitant
Liver Disorder Other Serious 52 Male 2/7/2007 Israel
Primary
Secondary
Jaundice Cholestatic Other Serious 52 Male 2/23/2007
Primary
Secondary
Somnolence Other Serious 56 Female 3/2/2007
Primary
Secondary
Metastasis Death 11 Female 3/5/2007
Primary
Secondary
Metastasis Death 11 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Female 3/5/2007
Primary
Secondary
Metastasis Death 12 Male 3/5/2007
Primary
Secondary
Metastasis Death 19 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Male 3/5/2007
Primary
Secondary
Papilloedema Hospitalization 10/1/2003 23 Male 2/28/2007 Japan
Primary
Secondary
Nervous System Disorder Death 11 Female 3/2/2007 Physician Germany
Primary
Secondary
Glioma Other Serious 5 Male 3/12/2007 Other Health Professional Finland
Primary
Secondary
Treatment Related Secondary Malignancy Death 11 Male 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 19 Male 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Male 3/1/2007 Germany
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 15 Female 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 11 Female 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 12 Male 3/1/2007 Germany
Primary
Secondary
Glioma Death 13 Female 3/1/2007 Germany
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 15 Male 3/16/2007 Germany
Primary
Secondary
Glioma Death 19 Male 3/16/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Female 3/16/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 12 Male 3/16/2007 Germany
Primary
Secondary
Glioblastoma Multiforme Death 11 Female 3/16/2007 Germany
Primary
Secondary
Glioma Death 13 Female 3/20/2007 Germany
Primary
Secondary
Glioma Death 11 Male 3/20/2007 Germany
Primary
Secondary
Neoplasm Malignant Death 15 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 13 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 11 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 15 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 19 Male 3/30/2007 Germany
Primary
Secondary
Neoplasm Malignant Death 12 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Sepsis Death 26 Female 4/11/2007
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 26 Female 4/6/2007 Other Health Professional Australia
Primary
Secondary
Malignant Melanoma In Situ Other Serious 22 Male 5/18/2007 Physician United States
Primary
Secondary
Pneumonia Cytomegaloviral Other Serious 65 Female 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 19 Female 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 22 Male 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 22 Male 6/8/2007 Other Health Professional United States
Primary
Secondary
Malignant Melanoma In Situ Other Serious Male 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death Male 6/12/2007
Primary
Secondary
Malignant Melanoma In Situ Other Serious 22 Male 6/12/2007
Primary
Secondary
Malignant Melanoma In Situ Other Serious Male 6/12/2007 United States
Primary
Secondary
Xerosis Hospitalization 11 Male 6/13/2007 Physician United States
Primary
Concomitant
Peroneal Nerve Palsy Hospitalization 6/18/2005 15 Female 108 lb 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 6/18/2005 15 Female 6/13/2007 United Kingdom
Primary
Secondary
Concomitant
Prophylaxis Hospitalization 6/18/2005 15 Female 6/13/2007 United Kingdom
Primary
Secondary
Concomitant
Polyneuropathy Other Serious Female 6/22/2007
Primary
Secondary
Polyneuropathy Other Serious Male 6/22/2007
Primary
Secondary
Peroneal Nerve Palsy Hospitalization 6/18/2005 15 Female 108 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Infection Other Serious 8 Male 7/3/2007
Primary
Secondary
Polyneuropathy Other Serious Female 7/5/2007
Primary
Secondary
Polyneuropathy Other Serious Male 7/5/2007
Primary
Secondary
Trichostasis Spinulosa Other Serious 6 Male 6/30/2007 Physician Australia
Primary
Secondary
Rash Papulosquamous Other Serious 8 Male 6/30/2007 Physician Australia
Primary
Secondary
Malignant Melanoma In Situ Other Serious Male 7/16/2007 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 5 Female 8/18/2007 Physician United States
Primary
Secondary
Concomitant
Quadriplegia Other Serious 4 Female 9/13/2007 Physician Italy
Primary
Secondary
Concomitant
Precocious Puberty Other Serious Female 9/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Death 1 Female 9/10/2007 Argentina
Primary
Secondary
Disease Recurrence Death 5 Male 9/10/2007 Argentina
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 9 Female 9/10/2007 Argentina
Primary
Secondary
Post Procedural Complication Hospitalization 14 Male 9/19/2007 Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 9/27/2007 Male 187 lb 10/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 52 Male 10/26/2007 Israel
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 11 Male 10/30/2007 Physician United States
Primary
Concomitant
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Glioma Death 13 Female 11/21/2007 Germany
Primary
Secondary
Glioma Death 15 Female 11/21/2007 Germany
Primary
Secondary
Nervous System Disorder Death 12 Male 11/21/2007 Physician Germany
Primary
Secondary
Glioma Death 11 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 16 Female 12/11/2007 Physician United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 17 Male 12/18/2007 United States
Primary
Secondary
Systemic Candida Hospitalization 26 Male 12/19/2007 Germany
Primary
Secondary
Vomiting Other Serious 2 Female 2/7/2008 Physician Canada
Primary
Secondary
Concomitant
Hypokalaemia Other Serious Female 2/8/2008 Canada
Primary
Concomitant
Haematuria Other Serious 16 Male 2/21/2008 Physician Japan
Primary
Secondary
Transaminases Increased Other Serious 5 Female 3/10/2008
Primary
Secondary
Concomitant
Splenomegaly Other Serious 4 Female 3/15/2008 Physician United States
Primary
Secondary
Lymphoproliferative Disorder Other Serious 4 Female 3/20/2008 United States
Primary
Secondary
White Blood Cell Count Decreased Death 4 Male 3/18/2008 Physician Switzerland
Primary
Secondary
Viral Dna Test Positive Other Serious 4 Female 3/19/2008 Physician United States
Primary
Secondary
Ewing's Sarcoma Other Serious 16 Male 3/31/2008
Primary
Secondary
Concomitant
Sinusitis Fungal Other Serious Female 3/31/2008 Physician United States
Primary
Secondary
Protein Total Decreased Other Serious Male 176 lb 4/21/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/1/1996 Female 109 lb 4/22/2008 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 16 Male 5/24/2008 Physician Turkey
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 6 Female 6/3/2008 Spain
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 6 Female 6/13/2008 Spain
Primary
Secondary
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11 Male 6/20/2008 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 6/26/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 6/30/2008 Consumer United States
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/9/2008 Consumer United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/15/2008 United Kingdom
Primary
Secondary
Paraplegia Disability 25 Female 7/3/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Neoplasm Malignant Life Threatening 54 Male 7/16/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/17/2008 Consumer United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/17/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/25/2008 United Kingdom
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/28/2008 United Kingdom
Primary
Secondary
Promyelocyte Count Increased Life Threatening 54 Male 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 8/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Urticaria Disability 8/19/2008 Female 26 lb 9/9/2008 Pharmacist United States
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 54 Male 9/29/2008 United Kingdom
Primary
Secondary
Platelet Count Decreased Other Serious 1/1/2006 46 Male 10/20/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypotension Hospitalization 12/2/2007 Female 10/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/24/2008 Female 205 lb 10/16/2008 United States
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 8/15/2008 United Kingdom
Primary
Secondary
Skin Nodule Other Serious 1/1/2006 36 Female 12/1/2008 Other Health Professional Germany
Primary
Concomitant
Pneumonia Other Serious 45 Male 12/2/2008
Primary
Secondary

Drug Data