Cyclosporine combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Visual Field Defect Other Serious Female 7/13/2006
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 55 Female 9/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 10/20/2006 17 Female 112 lb 12/18/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 54 Male 205 lb 1/12/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/1999 54 Male 205 lb 2/1/2007 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 56 Female 3/2/2007
Primary
Secondary
White Blood Cell Count Increased Other Serious 1/1/1999 54 Male 205 lb 3/21/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2004 47 Female 3/29/2007 Physician Poland
Primary
Secondary
Concomitant
Venoocclusive Disease Death 47 Male 5/20/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/1999 54 Male 205 lb 6/12/2007 United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious Female 8/10/2007 Physician United States
Primary
Secondary
Myeloid Leukaemia Other Serious Female 8/10/2007 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious Female 8/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 3 Female 8/29/2007 United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Transplant Life Threatening 9 Female 9/7/2007 Physician Hong Kong
Primary
Secondary
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death Female 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Bone Marrow Transplant Other Serious 9 Female 10/22/2007 United Kingdom
Primary
Secondary
Chromosomal Deletion Other Serious 9 Female 10/27/2007 Physician United States
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2004 Male 11/8/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/5/2007 Switzerland
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Stress Other Serious 28 Male 12/14/2007 Australia
Primary
Secondary
Systemic Candida Hospitalization 26 Male 12/19/2007 Germany
Primary
Secondary
Vomiting Other Serious 39 Female 2/21/2008
Primary
Secondary
Vomiting Other Serious 6 Male 3/15/2008 Physician United States
Primary
Secondary
Concomitant
Viral Diarrhoea Death 6 Male 3/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Death 58 Male 3/29/2008 Physician Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 57 Female 4/17/2008 Physician United States
Primary
Concomitant
Subdural Effusion Other Serious 6 Male 4/16/2008 Consumer United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 57 Female 4/21/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 45 Male 5/2/2008 Japan
Primary
Concomitant
Renal Failure Life Threatening 3/27/2008 Female 5/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 5 Female 5/13/2008
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 1/1/2004 Male 5/15/2008 Other Health Professional Germany
Primary
Secondary
Venous Pressure Jugular Increased Hospitalization 24 Male 6/2/2008 United States
Primary
Secondary
Surgery Other Serious 7/1/2004 6/23/2008 Other Health Professional
Primary
Concomitant
Pulmonary Sepsis Life Threatening 6/1/2004 51 Male 7/7/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2005 Male 8/6/2008 Other Health Professional Germany
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 43 Male 8/26/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Urticaria Other Serious 8/8/2008 Female 8/27/2008 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 72 Male 10/6/2008 Other Health Professional Japan
Primary
Concomitant
Urticaria Other Serious 8/8/2008 Female 10/14/2008 Physician United States
Primary
Concomitant
Large Intestinal Ulcer Other Serious 3/1/2006 56 Female 10/15/2008
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 23 Male 10/17/2008 Other Health Professional Japan
Primary
Secondary
Respiratory Failure Death 72 Male 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 10/23/2008 Physician Italy
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 10/24/2008 Physician Italy
Primary
Secondary
Concomitant
Sepsis Death 55 Male 10/21/2008 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 11/3/2008 Physician Italy
Primary
Secondary
Concomitant
B-cell Lymphoma Recurrent Other Serious 7/1/2005 Male 11/11/2008 Physician Germany
Primary
Secondary
Concomitant
Sepsis Death 6/1/2005 Male 11/12/2008 Physician Germany
Primary
Secondary
Concomitant
Skin Nodule Other Serious 1/1/2006 36 Female 12/1/2008 Other Health Professional Germany
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 12/8/2008 Physician Italy
Primary
Secondary
Concomitant
Sepsis Other Serious Male 1/28/2009 Physician Germany
Primary
Concomitant
Ventricular Hypokinesia Other Serious 1/1/2007 3/12/2009 Other Health Professional Brazil
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 57 Female 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 16 5/8/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Death 5 Female 5/29/2009 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 1/23/2009 14 Female 5/28/2009 Netherlands
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 61 Male 6/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 1/23/2009 14 Female 6/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 5 Female 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Vascular Graft Complication Other Serious 9 Male 6/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Syncope Hospitalization 1/23/2009 14 Female 6/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 9 Male 7/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Vascular Graft Complication Other Serious 9 Male 7/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxoplasmosis Other Serious 40 Male 7/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Transplant Other Serious 13 Male 7/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2009 54 Female 8/20/2009 Other Health Professional China
Primary
Secondary
Tumour Lysis Syndrome Other Serious 13 Male 8/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Transplant Other Serious 13 Male 8/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 1/26/2009 14 Female 10/6/2009 Physician Netherlands
Primary
Secondary
Concomitant
Splenomegaly Other Serious 8/1/2001 8 Female 10/22/2009
Primary
Secondary
Somnolence Life Threatening 9/16/2009 Male 120 lb 11/2/2009 Physician Netherlands
Primary
Concomitant
Somnolence Life Threatening 9/15/2009 Male 120 lb 11/11/2009 Physician Netherlands
Primary
Concomitant
Pyrexia Other Serious 8 Female 12/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 1/1/2007 73 Male 12/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 73 Male 1/6/2010 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Death 12/8/2009 29 Female 1/13/2010 Physician Italy
Primary
Secondary
Weight Increased Hospitalization 6/1/2009 42 Male 1/13/2010 Physician United States
Primary
Concomitant
Agranulocytosis Other Serious 1/1/2007 73 Male 1/18/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Other Serious 17 Female 1/29/2010 Physician United States
Primary
Concomitant
Zygomycosis Other Serious 1/1/2006 Male 2/12/2010 Physician Italy
Primary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/17/2010 Physician Italy
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/19/2010 Physician Italy
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/25/2010 Other Health Professional Japan
Primary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/31/2010 Other Health Professional Japan
Primary
Concomitant
Swelling Face Other Serious 4 Male 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wernicke's Encephalopathy Disability 5/9/2008 4/13/2010 Physician United States
Primary
Secondary
Respiratory Failure Hospitalization 3/19/2008 4/13/2010 Physician United States
Primary
Secondary
Wernicke's Encephalopathy Disability 5/9/2008 4/20/2010 Physician United States
Primary
Secondary
Respiratory Failure Hospitalization 3/19/2008 4/20/2010 Physician United States
Primary
Secondary
Drug Ineffective Other Serious 9/10/2009 67 Female 4/22/2010 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Procedural Pain Other Serious 9/5/2009 67 Female 5/5/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 5/7/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 5/11/2010 Physician United States
Primary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Death Unknown 5/10/2010 France
Primary
Secondary
Pneumonia Bacterial Death 5/10/2010 France
Primary
Secondary
Pancreatitis Death 5/10/2010 France
Primary
Secondary
Therapeutic Response Decreased Other Serious 1/1/2009 70 Female 146 lb 5/17/2010 Physician United States
Primary
Concomitant
Retinoblastoma Unilateral Other Serious 10 6/1/2010 Physician United States
Primary
Concomitant
Drug Ineffective For Unapproved Indication Death 45 Male 6/10/2010 Italy
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 6/11/2010 Physician United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 54 Male 6/15/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 6/22/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2009 70 Female 146 lb 7/1/2010 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 49 Female 8/6/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Radical Mastectomy Other Serious 6/4/1999 46 Female 207 lb 8/9/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 49 Female 8/11/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 6/4/1999 46 Female 207 lb 8/28/2010 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 13 Male 9/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Peritonitis Bacterial Other Serious 5/1/2009 81 Male 9/22/2010
Primary
Secondary
Thrombotic Microangiopathy Other Serious 70 Male 9/17/2010 Physician Japan
Primary
Concomitant
Splenectomy Other Serious 17 Female 9/23/2010 Other Health Professional Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/6/2010 41 Male 9/30/2010 Physician United States
Primary
Secondary
Venous Thrombosis Limb Other Serious 6/4/1999 46 Female 207 lb 10/5/2010 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 6/4/1999 46 Female 207 lb 10/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/16/2010 61 Male 10/21/2010 Physician Germany
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 6/4/1999 46 Female 207 lb 10/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis B Other Serious 56 Male 12/1/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Haematochezia Hospitalization 1/1/2003 50 Female 207 lb 1/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Asthenia Other Serious 11/12/2009 73 Female 134 lb 1/21/2011 Physician Germany
Primary
Concomitant
Pleural Effusion Death 1/1/2003 50 Female 207 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 3 Male 3/1/2011 Other Health Professional United States
Primary
Concomitant
Electrolyte Imbalance Death 1/1/2003 50 Female 207 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 11/12/2009 73 Female 134 lb 3/17/2011 Physician Germany
Primary
Concomitant
Fluid Retention Other Serious 51 Male 4/1/2011 Other Health Professional Japan
Primary
Concomitant
Faecal Incontinence Disability 13 Female 3/28/2011 Other Health Professional United States
Primary
Concomitant
Paraplegia Hospitalization 16 Male 3/28/2011 Other Health Professional United States
Primary
Concomitant
Vasculitis Necrotising Death 4/10/2011 Physician Italy
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/1/2009 Female 4/15/2011 Pharmacist United States
Primary
Concomitant
Dental Caries Death 1/1/2003 50 Female 207 lb 4/19/2011 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/1/2009 Female 4/25/2011 Physician United States
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 16 Female 4/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Erosive Oesophagitis Hospitalization 1/1/2003 50 Female 207 lb 5/18/2011 United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 1 5/18/2011 Physician United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 2 5/18/2011 Other Health Professional United States
Primary
Concomitant
Neoplasm Progression Other Serious 3 5/18/2011 Other Health Professional United States
Primary
Concomitant
Peripheral Embolism Hospitalization 5/3/2011 87 Male 6/13/2011 Physician Australia
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 1/1/2003 50 Female 207 lb 6/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Embolism Hospitalization 5/3/2011 87 Male 7/11/2011 Physician Australia
Primary
Concomitant
Embolism Hospitalization 5/3/2011 87 Male 7/25/2011 Physician Australia
Primary
Concomitant
Wound Infection Hospitalization 1/1/2003 50 Female 207 lb 7/26/2011 United States
Primary
Secondary
Concomitant
Deafness Other Serious 1/1/2003 50 Female 207 lb 8/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 9/15/2008 10/7/2011 Consumer Netherlands
Primary
Secondary

Drug Data