Bortezomib combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 10/30/2006 63 Male 229 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Osteonecrosis Other Serious 10/1/2006 Male 5/14/2007 Physician Germany
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2006 Male 5/14/2007 Physician Germany
Primary
Concomitant
Pain In Jaw Hospitalization 6/30/2007 57 Male 230 lb 7/11/2007 Other Health Professional United States
Primary
Secondary
Rash Pustular Other Serious 65 Female 7/26/2007
Primary
Secondary
Tooth Extraction Other Serious 1/1/2007 Female 8/15/2007 Physician Germany
Primary
Concomitant
Sinusitis Hospitalization 11/29/2007 61 Male 204 lb 12/5/2007 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Other Serious 12/26/2007 54 Male 192 lb 12/27/2007 Other Health Professional United States
Primary
Secondary
Embolism Other Serious 2/1/2008 48 Male 282 lb 2/7/2008 Other Health Professional United States
Primary
Secondary
Pyrexia Other Serious 5/19/2008 74 Male 167 lb 5/19/2008 Other Health Professional United States
Primary
Secondary
Renal Injury Other Serious 5/28/2008 74 Male 156 lb 5/30/2008 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 6/26/2008 59 Male 198 lb 7/1/2008 Other Health Professional United States
Primary
Secondary
Tooth Extraction Other Serious 10/1/2004 Female 8/12/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2006 62 Female 9/26/2008
Primary
Secondary
Concomitant
Nausea Hospitalization 1/31/2006 Male 154 lb 10/23/2008 United States
Primary
Secondary
Concomitant
Nervous System Disorder Death 54 Male 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/8/2009 56 Male 254 lb 3/13/2009 Physician United States
Primary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 6/12/2009 Physician United Kingdom
Primary
Secondary
Staphylococcal Infection Other Serious 1/1/2008 43 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Stenotrophomonas Infection Life Threatening 7/28/2009 Female 21 lb 9/1/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/1/2009 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 12/3/2009 Consumer United Kingdom
Primary
Secondary
Staphylococcal Infection Life Threatening 10/19/2009 Female 59 lb 12/9/2009 Physician United States
Primary
Concomitant
Shock Other Serious 65 Male 4/7/2010
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 54 Male 6/15/2010 United States
Primary
Secondary
Concomitant
Cerebral Ischaemia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 7/30/2010 Physician United States
Primary
Secondary
Lipase Increased Other Serious 7/30/2010 Physician United States
Primary
Secondary
Hypocalcaemia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Depressed Level Of Consciousness Other Serious 7/30/2010 Physician United States
Primary
Secondary
Hypophosphataemia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Aspartate Aminotransferase Increased Other Serious 7/30/2010 Physician United States
Primary
Secondary
Myalgia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Syncope Other Serious 7/30/2010 Physician United States
Primary
Secondary
Caecitis Other Serious 7/30/2010 Physician United States
Primary
Secondary
Hypoalbuminaemia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Red Blood Cell Count Decreased Other Serious 8/23/2010 Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 8/27/2010 Physician Korea, Republic Of
Primary
Secondary
Thrombocytopenia Other Serious 9/1/2010 Physician United Kingdom
Primary
Secondary
Myoclonus Other Serious 1/12/2010 62 Male 9/10/2010 Physician Japan
Primary
Concomitant
Peripheral Sensory Neuropathy Other Serious 9/16/2010 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 10/14/2010 Physician United States
Primary
Secondary
Wound Infection Other Serious 10/26/2010 Physician United States
Primary
Secondary
Concomitant
Lung Infection Other Serious 3/1/2007 53 Male 11/11/2010 Consumer Germany
Primary
Concomitant
Thrombocytopenia Other Serious 12/10/2010 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 12/15/2010 Physician United States
Primary
Secondary
Neuropathy Peripheral Other Serious 59 Male 12/20/2010 Physician Greece
Primary
Secondary
Hypercalcaemia Hospitalization 67 Male 132 lb 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 55 1/28/2011 Other Health Professional United States
Primary
Secondary
Neuropathy Peripheral Other Serious 59 Male 2/2/2011 Physician Greece
Primary
Secondary
Neutropenia Other Serious Male 2/11/2011 Physician United Kingdom
Primary
Secondary
Haemochromatosis Other Serious 67 Male 132 lb 2/24/2011 Physician Japan
Primary
Secondary
Cardiomyopathy Other Serious 3/21/2011 Physician United Kingdom
Primary
Secondary
Pleural Effusion Other Serious 4/1/2011 Consumer United Kingdom
Primary
Secondary
Lung Infection Other Serious 3/1/2007 53 Male 4/5/2011 Consumer Germany
Primary
Concomitant
Peripheral Sensorimotor Neuropathy Hospitalization 12/26/2010 21 Male 127 lb 3/29/2011 Physician United States
Primary
Concomitant
Inflammation Other Serious 49 Male 4/27/2011 Other Health Professional Japan
Primary
Secondary
Myelodysplastic Syndrome Other Serious 3/28/2007 55 Female 5/11/2011 Other Health Professional United States
Primary
Secondary
Acute Graft Versus Host Disease In Intestine Other Serious 64 Female 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 60 Male 6/20/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Neutropenia Other Serious 8/18/2011 Consumer United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Death 9/2/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Paraparesis Death 55 Male 9/8/2011 Other Health Professional Belgium
Primary
Secondary
Diplopia Death 55 Male 9/8/2011 Other Health Professional Belgium
Primary
Secondary
Febrile Neutropenia Other Serious 11/8/2011 United States
Primary
Secondary
Disease Recurrence Hospitalization 5/15/2008 76 Male 174 lb 10/17/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2007 53 Male 12/1/2011 Other Health Professional United States
Primary
Concomitant
Neoplasm Malignant Disability 10/18/2011 16 Male 12/16/2011 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/11/2012 Japan
Primary
Secondary
Neoplasm Progression Other Serious 9/1/2007 64 Male 1/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Fracture Other Serious 1/24/2012 Physician United States
Primary
Secondary
Concomitant
Death Death 1/25/2012 Other Health Professional United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Other Serious 3/28/2007 55 Female 3/1/2012 Other Health Professional United States
Primary
Secondary
Osteonecrosis Of Jaw Other Serious 12/1/2010 59 Female 3/7/2012 Other Health Professional Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/10/2012 64 Female 222 lb 3/12/2012 Physician United States
Primary
Secondary
Multiple Myeloma Death 1/21/2012 62 Female 3/29/2012 Other Health Professional Italy
Primary
Concomitant
Infection Other Serious Male 3/30/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/9/2012 54 Male 4/3/2012 Physician United States
Primary
Secondary
Blood Pressure Systolic Increased Hospitalization 12/5/2011 52 Male 188 lb 4/6/2012 United States
Primary
Secondary
Bacterial Infection Death 4/9/2012 Other Health Professional United States
Primary
Secondary
Bacterial Infection Death 4/11/2012 Other Health Professional United States
Primary
Secondary
Plasmablastic Lymphoma Other Serious Male 4/12/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 11/23/2007 47 Female 194 lb 4/13/2012 Physician United States
Primary
Secondary
Concomitant
Zygomycosis Other Serious 4/13/2012 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Hospitalization 2/10/2012 64 Female 222 lb 4/20/2012 United States
Primary
Secondary
Neutropenia Other Serious Male 4/26/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Autoimmune Hepatitis Other Serious 56 Female 5/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 56 Female 5/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Disease Progression Other Serious 5/8/2012 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/20/2012 62 Female 6/13/2012 Other Health Professional Italy
Primary
Concomitant
Drug Ineffective Other Serious 51 Male 6/22/2012 Physician Turkey
Primary
Secondary
Adverse Event Other Serious 6/27/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Rash Other Serious 7/2/2012 Other Health Professional China
Primary
Secondary
Lung Infection Other Serious 7/3/2012 Physician China
Primary
Secondary
Polyneuropathy Other Serious 7/10/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Burkitt's Lymphoma Death 7/30/2012 Physician United States
Primary
Secondary
Concomitant
Somnolence Death 8/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Zygomycosis Other Serious 8/14/2012 Physician United States
Primary
Secondary
Neuropathy Peripheral Hospitalization 8/14/2012 Physician United States
Primary
Secondary
Concomitant
Off Label Use Death 8/14/2012 Physician United States
Primary
Secondary
Sepsis Death 8/14/2012 Physician United States
Primary
Secondary
Off Label Use Other Serious 8/16/2012 Physician United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 8/16/2012 Physician United States
Primary
Secondary
Off Label Use Other Serious 8/16/2012 Physician United States
Primary
Secondary
Cerebral Ischaemia Other Serious 8/16/2012 Physician United States
Primary
Secondary
Disease Progression Other Serious 8/16/2012 Physician United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 8/16/2012 Physician United States
Primary
Secondary
Coagulopathy Other Serious 8/16/2012 Physician United States
Primary
Secondary
Off Label Use Other Serious 8/16/2012 Physician United States
Primary
Secondary
Encephalopathy Other Serious 8/16/2012 Physician United States
Primary
Secondary
Off Label Use Other Serious 8/16/2012 Physician United States
Primary
Secondary
Lipase Abnormal Other Serious 8/16/2012 Physician United States
Primary
Secondary
Concomitant
Amylase Abnormal Other Serious 8/16/2012 Physician United States
Primary
Secondary
Bacterial Sepsis Death 8/17/2012 Physician United States
Primary
Secondary
Hypoxia Other Serious 8/17/2012 Physician United States
Primary
Secondary
Zygomycosis Other Serious 8/17/2012 Physician United States
Primary
Secondary
Off Label Use Death 8/20/2012 Physician United States
Primary
Secondary
Zygomycosis Other Serious 8/20/2012 Physician United States
Primary
Secondary
Hypophosphataemia Hospitalization 8/20/2012 Physician United States
Primary
Secondary
Concomitant
Hypoxia Other Serious 8/22/2012 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Death 11/23/2012 Physician Us
Primary
Secondary
Sepsis Death 12/31/2012 Physician Us
Primary
Secondary
Off Label Use Other Serious 12/14/2012 Physician Us
Primary
Secondary
Off Label Use Other Serious 11/23/2012 Physician Us
Primary
Secondary
Infection Other Serious 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Small Intestinal Perforation Other Serious 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Septic Shock Death 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Delirium Other Serious 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Hepatic Failure Death 44 Male 12/6/2012 Country Not Specified
Primary
Secondary
Sepsis Death 65 Male 12/6/2012 Country Not Specified
Primary
Secondary
Herpes Zoster Other Serious 61 Female 12/6/2012 Country Not Specified
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 56 Female 12/6/2012 Country Not Specified
Primary
Secondary
Vomiting Hospitalization 11/22/2012 37 Female 148 lb 1/4/2013 Physician Us
Primary
Secondary
Concomitant
Zygomycosis Death 54 Male 12/19/2012 De
Primary
Secondary
Cardio-respiratory Arrest Death 12/25/2012 65 Female 193 lb 2/26/2013 Consumer Us
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious NotSpecified 5/24/2013 Other Health Professional Country Not Specified
Primary
Secondary
Neuropathy Peripheral Other Serious 69 Male 3/19/2013 Physician Si
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious Male 4/15/2013 Physician Si
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious NotSpecified 4/15/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Other Serious NotSpecified 4/15/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Other Serious NotSpecified 4/15/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Other Serious NotSpecified 4/15/2013 Physician Us
Primary
Secondary
Staphylococcal Infection Hospitalization 64 Female 5/6/2013 Other Health Professional Tr
Primary
Secondary
Concomitant
Syncope Hospitalization 4/8/2013 72 Female 174 lb 5/7/2013 Physician Us
Primary
Secondary
Concomitant
Poems Syndrome Death NotSpecified 7/19/2013 Other Health Professional Cz
Primary
Secondary
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 7/24/2013 Physician Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 7/26/2013 Physician Gb
Primary
Secondary
Concomitant

Drug Data