Fludarabine combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Viral Infection Other Serious 10/7/2005 Male 199 lb 3/30/2006 Physician United States
Primary
Concomitant
Shock Death 8/2/2005 70 Male 187 lb 4/4/2006 Physician Italy
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/23/2006 Male 5/15/2006 Physician Hungary
Primary
Concomitant
Superinfection Life Threatening 2/15/2003 76 Male 214 lb 5/19/2006 Physician France
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/23/2006 Male 6/7/2006 Physician Hungary
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 62 Female 10/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2006 62 Female 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/1999 54 Male 10/13/2006
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 62 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 42 Female 10/27/2006 Physician Turkey
Primary
Secondary
Somnolence Other Serious 56 Female 3/2/2007
Primary
Secondary
Viral Infection Life Threatening 62 Female 3/5/2007
Primary
Secondary
Concomitant
Neutropenia Other Serious Female 3/6/2007 United Kingdom
Primary
Secondary
Sepsis Other Serious 25 Male 3/7/2007 Australia
Primary
Secondary
Concomitant
Spinal Cord Disorder Other Serious 25 Male 4/4/2007 Other Health Professional Australia
Primary
Secondary
Spinal Cord Disorder Other Serious 25 Male 4/10/2007 Other Health Professional Australia
Primary
Secondary
Sepsis Death 25 Male 4/11/2007
Primary
Secondary
Myelodysplastic Syndrome Life Threatening 2/21/2007 65 Female 4/11/2007 Other Health Professional United States
Primary
Concomitant
Spinal Cord Disorder Other Serious 25 Male 4/13/2007 Consumer United States
Primary
Secondary
Stem Cell Transplant Other Serious 49 Female 4/30/2007 United Kingdom
Primary
Secondary
Viral Infection Death 62 Female 1/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myelomonocytic Leukaemia Death 68 Male 2/23/2008 Consumer United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 75 Female 2/23/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 58 2/26/2008 Consumer United Kingdom
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious Female 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 45 Female 2/27/2008 Physician United States
Primary
Secondary
Therapeutic Response Decreased Death 68 Male 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Death 75 Female 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 58 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Respiratory Failure Other Serious 8/1/2003 76 Female 8/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 44 Male 8/21/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Fungal Death 76 Female 8/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukaemia Other Serious 5/1/2008 66 Male 10/28/2008 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/16/2009 Other Health Professional United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 6/1/2008 59 Female 9/25/2009 Other Health Professional United States
Primary
Secondary
Renal Colic Hospitalization 69 Male 10/14/2009 Physician United Kingdom
Primary
Concomitant
Somnolence Life Threatening 9/16/2009 Male 120 lb 11/2/2009 Physician Netherlands
Primary
Concomitant
Somnolence Life Threatening 9/15/2009 Male 120 lb 11/11/2009 Physician Netherlands
Primary
Concomitant
Colitis Ulcerative Hospitalization 11/11/2009 Physician United Kingdom
Primary
Concomitant
Renal Colic Hospitalization 4/15/2009 Male 165 lb 12/2/2009 Physician United Kingdom
Primary
Concomitant
Colitis Ulcerative Hospitalization Female 12/4/2009 Physician United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2006 Male 12/10/2009 Consumer United Kingdom
Primary
Secondary
Pulmonary Embolism Death 11/9/2009 Female 12/24/2009 Consumer United Kingdom
Primary
Concomitant
Gene Mutation Other Serious 7/25/2007 52 Male 12/29/2009 Czech Republic
Primary
Concomitant
Gastrointestinal Toxicity Other Serious 17 Female 1/29/2010 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 5/1/2008 Male 172 lb 2/4/2010 Other Health Professional United States
Primary
Concomitant
Death Death 1/17/2009 67 Female 2/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Encephalitis Death 8/26/2009 Male 3/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/17/2010 Physician Italy
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/19/2010 Physician Italy
Primary
Secondary
Concomitant
Wernicke's Encephalopathy Disability 5/9/2008 4/13/2010 Physician United States
Primary
Secondary
Septic Shock Other Serious 61 Female 4/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Wernicke's Encephalopathy Disability 5/9/2008 4/20/2010 Physician United States
Primary
Secondary
Pyrexia Other Serious 1/1/2007 56 Male 4/22/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2007 56 Male 4/26/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Colitis Ulcerative Hospitalization 10/5/2009 82 Female 99 lb 6/11/2010 Physician United Kingdom
Primary
Secondary
Acute Respiratory Distress Syndrome Death 54 Male 6/15/2010 United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 10/11/2009 44 Male 7/7/2010 Physician United Kingdom
Primary
Concomitant
Lung Disorder Hospitalization 4/1/2010 61 Female 198 lb 7/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 49 Female 8/6/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of The Cervix Other Serious 50 Female 8/10/2010 Other Health Professional Germany
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 2/25/2009 59 Male 11/4/2010 Other Health Professional Japan
Primary
Concomitant
Pneumatosis Intestinalis Other Serious 12/2/2009 61 Male 12/1/2010 Other Health Professional Japan
Primary
Concomitant
Chronic Lymphocytic Leukaemia Transformation Death 74 Female 12/22/2010 Consumer United Kingdom
Primary
Secondary
Chronic Lymphocytic Leukaemia Transformation Other Serious 67 Male 12/22/2010 Consumer United Kingdom
Primary
Secondary
Pleural Effusion Death 5 Male 3/18/2011 Other Health Professional Japan
Primary
Secondary
Pulmonary Tuberculosis Other Serious 60 Male 3/18/2011 Other Health Professional Romania
Primary
Secondary
Skin Erosion Death 12 Male 3/23/2011 Physician Japan
Primary
Secondary
Concomitant
Skin Erosion Death 12 Male 3/23/2011 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 12 Male 3/23/2011 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 12 Male 3/23/2011 Physician Japan
Primary
Secondary
Concomitant
Ileus Paralytic Death 12 Male 3/23/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatitis B Other Serious 3/25/2011 Other Health Professional Japan
Primary
Secondary
Skin Erosion Death Male 4/1/2011 Other Health Professional Japan
Primary
Secondary
Fluid Retention Other Serious 51 Male 4/1/2011 Other Health Professional Japan
Primary
Concomitant
Diabetes Mellitus Other Serious 4/7/2011 Other Health Professional Romania
Primary
Secondary
Concomitant
Brain Natriuretic Peptide Increased Disability 51 Male 4/15/2011 Other Health Professional Japan
Primary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Death 11 Male 4/26/2011 Other Health Professional Japan
Primary
Secondary
Osteoporotic Fracture Other Serious 1/27/2012 France
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 34 Female 12/5/2013 Physician Jp
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 8/15/2011 53 Female 209 lb 10/17/2013 Physician Gb
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 3 Male 11/20/2013 Other Health Professional Pl
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/16/2012 59 Male 214 lb 12/9/2013 Other Health Professional Us
Primary
Concomitant
Thrombocytopenia Other Serious NotSpecified 5/16/2013 Other Health Professional It
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 8/15/2011 53 Female 209 lb 11/8/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Off Label Use Death 9/12/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Venoocclusive Disease Death 9/13/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Off Label Use Death 9/13/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Visceral Leishmaniasis Death 72 Female 9/10/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Toxicity To Various Agents Other Serious 9/24/2012 Other Health Professional Fi
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 9/28/2012 Other Health Professional Fi
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Hospitalization 9/20/2012 Other Health Professional Fi
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 9/20/2012 Other Health Professional Fi
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 9/24/2012 Other Health Professional Fi
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 9/21/2012 Other Health Professional Fi
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 10/2/2012 Physician Us
Primary
Concomitant
Vaginal Haemorrhage Other Serious Female 10/4/2012 Physician Us
Primary
Concomitant
Hodgkin's Disease Other Serious 57 Male 10/14/2012 Physician Fr
Primary
Secondary
Concomitant
Spleen Disorder Other Serious 9/9/2001 66 Male 10/6/2012 Physician Us
Primary
Concomitant
Neutropenia Other Serious 10/19/2012 Other Health Professional Country Not Specified
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1992 Male 10/9/2012 Physician Us
Primary
Concomitant
Splenomegaly Other Serious Female 106 lb 10/8/2012 Other Health Professional Us
Primary
Concomitant
Dyspepsia Hospitalization 10/5/2009 83 Female 99 lb 1/2/2013 Physician Fr
Primary
Secondary
Hodgkin's Disease Other Serious 57 Male 10/22/2012 Country Not Specified
Primary
Secondary
Death Death 11/12/2012 Other Health Professional Gb
Primary
Secondary
Lymphoma Transformation Other Serious 11/23/2012 Other Health Professional Gb
Primary
Secondary
Lymphoma Transformation Other Serious 11/23/2012 Other Health Professional Gb
Primary
Secondary
Toxicity To Various Agents Other Serious 11/23/2012 Other Health Professional Gb
Primary
Secondary
Liver Injury Other Serious 11/20/2012 Physician Country Not Specified
Primary
Secondary
Thrombocytopenia Other Serious 73 Female 12/27/2012 Pharmacist Es
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization Female 12/11/2012 Physician Fr
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 11/18/2010 74 Male 209 lb 2/22/2013 Physician Country Not Specified
Primary
Secondary
Myelodysplastic Syndrome Death 1/14/2008 63 Male 12/14/2012 Other Health Professional Se
Primary
Secondary
Myelodysplastic Syndrome Death 11/18/2010 Male 209 lb 2/14/2013 Physician Fr
Primary
Secondary
Renal Failure Acute Other Serious 54 Female 1/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 3/6/2013 Other Health Professional No
Primary
Secondary
Alanine Aminotransferase Increased Other Serious NotSpecified 5/24/2013 Other Health Professional Country Not Specified
Primary
Secondary
Graft Versus Host Disease Other Serious 2012 66 Male 8/21/2013 Physician Jp
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 75 Male 3/26/2013 Other Health Professional Us
Primary
Secondary
Weight Decreased Hospitalization 69 Male 4/11/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Treatment Failure Other Serious NotSpecified 4/26/2013 Other Health Professional De
Primary
Secondary
Febrile Neutropenia Other Serious 2013 Male 168 lb 5/2/2013 Consumer Ca
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 3/7/2013 75 Male 148 lb 7/25/2013 Physician It
Primary
Secondary
Concomitant
Tuberculosis Other Serious NotSpecified 6/27/2013 Physician De
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 75 Male 6/28/2013 Other Health Professional Us
Primary
Secondary
Myalgia Other Serious 2013 65 Female 203 lb 9/5/2013 Physician Ca
Primary
Secondary
Concomitant
Wound Other Serious 2009 58 Female 146 lb 7/2/2013 Consumer Ca
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 75 Male 7/8/2013 Other Health Professional Us
Primary
Secondary
Haematotoxicity Other Serious NotSpecified 7/15/2013 Other Health Professional Us
Primary
Secondary
Thrombocytopenia Death 3/2013 75 Male 7/25/2013 Physician Us
Primary
Secondary
Pyrexia Required Intervention 75 Male 7/11/2013 Other Health Professional Us
Primary
Secondary
Vasculitis Necrotising Other Serious 52 Male 7/23/2013 Other Health Professional Country Not Specified
Primary
Secondary
Respiratory Failure Death 1 Female 7/25/2013 Other Health Professional Country Not Specified
Primary
Secondary
Sepsis Death 44 Male 8/2/2013 Other Health Professional Es
Primary
Secondary
Concomitant
Second Primary Malignancy Other Serious 3 Female 8/1/2013 Physician Jp
Primary
Secondary
Meningitis Cryptococcal Other Serious Male 8/16/2013 Other Health Professional Fr
Primary
Secondary
Thrombocytopenia Death 7/13/2009 62 Male 12/5/2013 Physician Rs
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 5/30/2013 81 Male 165 lb 10/31/2013 Physician It
Primary
Secondary
Haemorrhage Intracranial Death 6/6/2013 33 Female 180 lb 10/3/2013 Physician Us
Primary
Secondary
Concomitant
Death Death NotSpecified 9/18/2013 Other Health Professional It
Primary
Secondary
Chronic Lymphocytic Leukaemia Hospitalization 66 Female 9/17/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 9/28/2013 Physician Us
Primary
Secondary
Thrombocytopenia Other Serious NotSpecified 10/9/2013 Physician Us
Primary
Secondary
Splenomegaly Other Serious 52 Female 10/14/2013 Other Health Professional Tr
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/23/2013 46 Male 234 lb 11/2/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 5/23/2013 46 Male 231 lb 11/4/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Wheezing Disability NotSpecified 5/29/2013 Physician Gb
Primary
Secondary

Drug Data