Oncaspar combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transverse Sinus Thrombosis Hospitalization 12/9/2005 Female 43 lb 4/4/2006 Physician United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 8/26/2005 7 Female 53 lb 3/30/2006 Other Health Professional United States
Primary
Concomitant
Swelling Face Other Serious 3/16/2005 4 Male 37 lb 3/30/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 16 Male 6/6/2006 Physician United States
Primary
Concomitant
Vomiting Life Threatening 8/15/2006 18 Female 124 lb 8/16/2006 Other Health Professional United States
Primary
Concomitant
Type Iv Hypersensitivity Reaction Required Intervention 7/20/2006 19 Male 146 lb 8/8/2006 Physician United States
Primary
Concomitant
Urticaria Required Intervention 7/20/2006 19 Male 146 lb 8/16/2006 Physician United States
Primary
Concomitant
Swelling Face Life Threatening 2/28/2006 14 Male 108 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Urticaria Generalised Life Threatening 7/24/2006 3 Female 33 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 12/26/2002 1 Male 26 lb 12/22/2006 United States
Primary
Secondary
Screaming Other Serious 7 Female 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Urticaria Other Serious 2/28/2006 14 Male 107 lb 3/27/2007 Pharmacist United States
Primary
Concomitant
Urticaria Other Serious 7/24/2006 3 Female 33 lb 3/27/2007 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 9/6/2006 3 Male 33 lb 3/27/2007 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 9/19/2006 18 Male 174 lb 3/27/2007 Pharmacist United States
Primary
Concomitant
Urticaria Life Threatening 6/19/2006 5 Male 44 lb 3/27/2007 Other Health Professional United States
Primary
Concomitant
Rash Hospitalization 8/8/2006 15 Male 121 lb 3/27/2007 Other Health Professional United States
Primary
Concomitant
Hyperammonaemia Hospitalization 8/24/2006 3 Female 36 lb 3/27/2007 Pharmacist United States
Primary
Concomitant
Hyperglycaemia Other Serious 2/17/2006 9 Female 3/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 4/18/2006 15 Male 154 lb 3/27/2007 Other Health Professional United States
Primary
Concomitant
Cardiomyopathy Hospitalization 4/17/2007 8 Male 57 lb 6/5/2007
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/6/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/13/2007 3 Female 37 lb 5/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 2 Male 8/28/2008 United Kingdom
Primary
Secondary
Hepatic Encephalopathy Hospitalization 2 Male 10/27/2008 United Kingdom
Primary
Secondary
Hepatic Encephalopathy Hospitalization 2 Male 11/28/2008 United Kingdom
Primary
Secondary
Grand Mal Convulsion Hospitalization 12/10/2008 26 Female 143 lb 1/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Other Serious 12/11/2008 2/13/2009 Other Health Professional France
Primary
Secondary
Concomitant
Laboratory Test Abnormal Other Serious 3/2/2009 13 Female 176 lb 3/18/2009 Physician United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 3/4/2009 23 Male 116 lb 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 3/2/2009 13 Female 176 lb 3/31/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 2/24/2009 29 Female 112 lb 4/13/2009 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 3/2/2009 13 Female 176 lb 4/21/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/9/2009 Male 213 lb 5/26/2009 Physician United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 5/9/2009 14 Male 213 lb 6/3/2009 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 3/2/2009 13 Female 176 lb 6/29/2009 Physician United States
Primary
Secondary
Hepatotoxicity Other Serious 5/1/2009 24 Female 203 lb 8/6/2009 Pharmacist United States
Primary
Concomitant
Shock Hospitalization 7/30/2009 15 Female 153 lb 8/14/2009 Physician United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 5/9/2009 14 Male 213 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia 6/4/2009 Male 170 lb 8/27/2009 United States
Primary
Secondary
Shock Hospitalization 7/30/2009 15 Female 153 lb 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 5/9/2009 14 Male 213 lb 9/3/2009 Physician United States
Primary
Secondary
Concomitant
Tinnitus Required Intervention 7/6/2009 10 Male 122 lb 9/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 9/10/2008 81 Female 9/21/2009 United States
Primary
Concomitant
Injection Site Reaction Other Serious 1/1/2008 42 Female 9/21/2009 United States
Primary
Secondary
Concomitant
Lipase Increased Other Serious 7/10/2009 3 Female 33 lb 9/29/2009 Physician United States
Primary
Secondary
Concomitant
Pneumomediastinum Hospitalization 7/30/2009 15 Female 153 lb 10/7/2009 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 5/20/2009 19 Female 10/12/2009 Pharmacist New Zealand
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 7/10/2009 3 Female 33 lb 10/19/2009 Physician United States
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 2 Male 12/3/2009 Physician Canada
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 10/4/2009 11 Female 81 lb 12/22/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/7/2009 17 Male 146 lb 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 18 Male 1/7/2010 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 1 Male 1/7/2010 Physician United States
Primary
Concomitant
Screaming Hospitalization 10/4/2009 11 Female 81 lb 1/19/2010 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Other Serious 17 Female 1/29/2010 Physician United States
Primary
Concomitant
Hypertriglyceridaemia Other Serious 7/10/2009 3 Female 33 lb 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/7/2009 17 Male 146 lb 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 5/9/2009 14 Male 213 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/7/2009 17 Male 146 lb 3/11/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/24/2010 60 Male 184 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 3/14/2010 9 Male 95 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 1/20/2009 16 Female 109 lb 3/25/2010 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 2/4/2009 16 Male 157 lb 3/25/2010 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Life Threatening 2/24/2009 77 Female 126 lb 3/25/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/11/2008 16 Female 133 lb 3/25/2010 Other Health Professional United States
Primary
Concomitant
Pruritus Life Threatening 5/26/2009 13 Male 120 lb 3/25/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Life Threatening 5/18/2009 3 Male 3/25/2010 Other Health Professional United States
Primary
Concomitant
Urticaria Life Threatening 5/18/2009 Female 121 lb 3/25/2010 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 9/8/2009 6 Female 51 lb 3/25/2010 United States
Primary
Concomitant
Urticaria Life Threatening 8/13/2009 13 Male 207 lb 3/25/2010 United States
Primary
Concomitant
Shock Hospitalization 7/30/2009 15 Female 153 lb 4/7/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/14/2010 9 Male 95 lb 4/22/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/21/2010 42 Female 5/5/2010 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 4/21/2010 42 Female 5/13/2010 Physician United States
Primary
Secondary
Urticaria 5/17/2010 2 Female 22 lb 5/20/2010 Pharmacist United States
Primary
Secondary
Weight Decreased Hospitalization 3/14/2010 9 Male 95 lb 5/21/2010 Physician United States
Primary
Secondary
Concomitant
Ocular Icterus Hospitalization 5/28/2010 16 Male 227 lb 6/15/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/14/2010 9 Male 95 lb 6/22/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 3/2/2009 13 Female 144 lb 7/30/2010 Physician United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 5/28/2010 16 Male 227 lb 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Scoliosis Hospitalization 12/7/2009 17 Male 146 lb 8/12/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/12/2010 12 Female 8/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 5/26/2010 31 Male 8/16/2010 Physician United States
Primary
Secondary
Ocular Icterus Other Serious 5/28/2010 16 Male 227 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/28/2010 16 Male 227 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2009 16 Female 153 lb 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/6/2010 45 Male 9/14/2010 Physician Canada
Primary
Secondary
Concomitant
Scoliosis Hospitalization 12/7/2009 17 Male 146 lb 10/1/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/9/2009 14 Male 213 lb 10/13/2010 Physician United States
Primary
Secondary
Concomitant
Low Density Lipoprotein Increased Other Serious 7/10/2009 3 Female 33 lb 10/13/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/14/2010 9 Male 95 lb 10/19/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/14/2010 32 Male 10/25/2010 Physician United States
Primary
Secondary
Concomitant
Intracranial Venous Sinus Thrombosis Hospitalization 5/26/2010 31 Male 10/25/2010 Physician United States
Primary
Secondary
Pneumomediastinum Hospitalization 7/30/2009 15 Female 153 lb 10/26/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/17/2010 23 Female 228 lb 10/20/2010 Physician United States
Primary
Concomitant
Pneumomediastinum Hospitalization 7/30/2009 15 Female 153 lb 11/11/2010 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/28/2010 16 Male 227 lb 11/11/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/17/2010 23 Female 228 lb 11/16/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/14/2010 11/19/2010 United States
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 10/19/2010 15 Male 304 lb 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/17/2010 23 Female 228 lb 12/9/2010 Physician United States
Primary
Secondary
Proteinuria Hospitalization 11/22/2010 13 Female 98 lb 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 11/22/2010 13 Female 98 lb 2/8/2011 Physician United States
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 5/28/2010 16 Male 227 lb 2/15/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/22/2010 13 Female 98 lb 2/15/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 8/6/2010 45 Male 2/22/2011 Physician Canada
Primary
Secondary
Platelet Count Decreased Death 3/3/2011 14 Female 90 lb 3/16/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/20/2010 15 Female 143 lb 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 2/7/2011 14 Female 98 lb 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/26/2011 4 Male 36 lb 5/6/2011 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/20/2010 15 Female 143 lb 7/14/2011 Physician United States
Primary
Secondary
Concomitant
Hypotension Other Serious 6/29/2011 20 Female 115 lb 7/22/2011 Physician United States
Primary
Secondary
Hypertriglyceridaemia Other Serious 6/28/2011 15 Male 7/27/2011 United States
Primary
Secondary
Concomitant
Hyperbilirubinaemia Death 6/16/2011 23 Male 7/28/2011 Physician United States
Primary
Secondary
Ischaemic Cerebral Infarction Hospitalization 4/18/2011 13 Female 96 lb 8/5/2011 Physician United States
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 6/16/2011 23 Male 307 lb 8/18/2011 Physician United States
Primary
Secondary
Concomitant
Throat Irritation Hospitalization 8/4/2011 10 Female 75 lb 8/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 8/13/2011 8 Male 46 lb 10/12/2011 Pharmacist United States
Primary
Concomitant
Respiratory Distress Other Serious 10/3/2011 7 Male 49 lb 10/12/2011 Pharmacist United States
Primary
Concomitant
Eye Swelling Hospitalization 9/20/2011 7 Female 87 lb 12/5/2011 Pharmacist United States
Primary
Concomitant
Hypotonia Hospitalization 9/20/2011 11 Female 107 lb 12/5/2011 Pharmacist United States
Primary
Concomitant
Hypotonia Life Threatening 9/20/2011 9 Female 87 lb 12/5/2011 Pharmacist United States
Primary
Concomitant
Herpes Zoster Hospitalization 1/23/2012 18 Male 159 lb 2/17/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Other Serious 12 Female 2/28/2012 Physician Netherlands
Primary
Secondary
Procedural Pain Hospitalization 2/7/2012 6 Male 77 lb 3/12/2012 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 3/16/2012 Physician Netherlands
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 3/21/2012 6 Male 50 lb 3/26/2012 Pharmacist United States
Primary
Concomitant
Pancreatitis Hospitalization 9/23/2011 Male 89 lb 3/26/2012 Pharmacist United States
Primary
Concomitant
Pancreatitis Hospitalization 11/10/2011 12 Male 123 lb 3/26/2012 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 3/4/2012 18 Male 279 lb 4/2/2012 Physician United States
Primary
Secondary
Hypokalaemia Hospitalization 3/6/2012 13 Female 143 lb 4/24/2012 Physician United States
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 2/22/2012 17 Male 99 lb 4/24/2012 Physician United States
Primary
Secondary
Concomitant
Retching Hospitalization 3/22/2012 7 Female 86 lb 5/16/2012 United States
Primary
Secondary
Pyrexia Hospitalization 5/20/2012 10 Male 49 lb 5/24/2012 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 5/12/2012 17 Female 105 lb 6/8/2012 Physician United States
Primary
Secondary
Concomitant
Cyanosis Life Threatening 5/23/2011 3 Male 38 lb 3/29/2012 Other Health Professional United States
Primary
Concomitant
Cough Life Threatening 8/11/2011 15 Female 137 lb 3/29/2012 Pharmacist United States
Primary
Concomitant
Lip Swelling Life Threatening 6/22/2011 15 Female 108 lb 3/29/2012 Pharmacist United States
Primary
Concomitant
Cough Life Threatening 10/17/2011 18 Female 147 lb 3/29/2012 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 12/13/2010 14 Female 108 lb 7/30/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Death Death 8/15/2012 Physician United States
Primary
Secondary
Death Death 8/15/2012 Physician United States
Primary
Secondary
Death Death 8/15/2012 Physician United States
Primary
Secondary
Death Death 8/15/2012 Physician United States
Primary
Secondary
Tachycardia Hospitalization 3/26/2012 13 Female 114 lb 3/28/2012 Us
Primary
Concomitant
Thrombocytopenia Hospitalization 9/5/2012 12 Male 10/17/2012 Physician Us
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/29/2012 10 Male 11/5/2012 Physician Us
Primary
Secondary
Concomitant
Laryngitis Fungal Death Male 7/15/2013 Other Health Professional Gb
Primary
Secondary
Urticaria Hospitalization 7/3/2013 6 Female 43 lb 7/11/2013 Other Health Professional Us
Primary
Concomitant

Drug Data