Ara-C combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Hypertrophy Life Threatening 3/27/2006 Female 116 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 16 Male 6/6/2006 Physician United States
Primary
Concomitant
Rash Hospitalization Male 212 lb 6/30/2006 Physician Germany
Primary
Concomitant
Tongue Disorder Hospitalization 6/1/2006 Male 212 lb 7/18/2006 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/15/2006 18 Female 124 lb 8/16/2006 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 9/4/2006 24 Male 176 lb 9/5/2006 Other Health Professional United States
Primary
Secondary
Vertigo Hospitalization 7/16/2006 57 Male 198 lb 9/5/2006 United Kingdom
Primary
Concomitant
Pyrexia Other Serious 9/11/2006 35 Male 154 lb 9/19/2006 Physician France
Primary
Secondary
Pyrexia Other Serious 9/11/2006 35 Male 154 lb 9/19/2006 Physician France
Primary
Secondary
Weight Increased Required Intervention 9/18/2006 Male 36 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Hyponatraemia Required Intervention 9/5/2006 8 Male 61 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 12/6/2006 Other Health Professional Norway
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 NotSpecified 1/19/2007 Other Health Professional Norway
Primary
Concomitant
Musculoskeletal Disorder Hospitalization 6/16/2008 7/28/2008 Physician Italy
Primary
Secondary
Musculoskeletal Disorder Hospitalization 6/16/2008 8/4/2008 Physician Italy
Primary
Secondary
Peripheral Sensory Neuropathy Hospitalization 6/1/2008 61 Female 8/8/2008 Physician Italy
Primary
Secondary
Septic Shock Hospitalization 8/26/2008 9/3/2008 Physician Italy
Primary
Secondary
Peripheral Sensory Neuropathy Hospitalization 6/16/2008 61 Female 9/8/2008 Physician Italy
Primary
Secondary
Thrombotic Microangiopathy Other Serious 23 Male 10/17/2008 Other Health Professional Japan
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 10/24/2008 Physician Italy
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 11/3/2008 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 45 Male 12/2/2008
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 12/8/2008 Physician Italy
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10/1/2004 69 Female 12/16/2008 Consumer United Kingdom
Primary
Secondary
Gamma-glutamyltransferase Increased Hospitalization 12/21/2008 4 Male 44 lb 1/7/2009 Physician Germany
Primary
Secondary
Concomitant
Puncture Site Infection Hospitalization 12/21/2008 4 Male 44 lb 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
Ischaemic Stroke Other Serious 63 Male 3/27/2009 Consumer United States
Primary
Concomitant
Peripheral Sensory Neuropathy Other Serious 3/4/2009 23 Male 116 lb 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/1/2008 75 Female 4/3/2009 Physician Italy
Primary
Secondary
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 6/26/2009 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/1/2007 Female 7/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/1/2007 Female 7/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 57 Male 8/6/2009
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 5/1/2009 24 Female 203 lb 8/6/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Life Threatening 10/7/2009 Female 10/20/2009 Physician France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 74 Female 10/26/2009 Other Health Professional Japan
Primary
Secondary
Weight Decreased Other Serious 6/1/2001 61 Male 11/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 42 Male 12/11/2009 Consumer United Kingdom
Primary
Secondary
Neutropenia Other Serious 17 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Terminal State Other Serious Female 1/7/2010 United States
Primary
Secondary
Terminal State Other Serious Female 1/12/2010 United States
Primary
Secondary
Respiratory Failure Death 12/8/2009 29 Female 1/13/2010 Physician Italy
Primary
Secondary
Renal Impairment Other Serious 17 Male 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/10/2010 Male 157 lb 1/29/2010 Physician Brazil
Primary
Secondary
Renal Failure Life Threatening 10/7/2009 Female 126 lb 2/1/2010 Physician France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/17/2010 Physician Italy
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/19/2010 Physician Italy
Primary
Secondary
Concomitant
Rash Other Serious 67 Female 3/29/2010 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 17 Male 3/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 3/19/2010 United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 17 Male 3/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 4/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Pancreatitis Hospitalization 2/4/2009 16 Male 157 lb 3/25/2010 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 67 Female 129 lb 4/1/2010 Other Health Professional Japan
Primary
Concomitant
Hypertension Hospitalization 10/4/2008 67 Female 4/13/2010 Physician United States
Primary
Secondary
Wernicke's Encephalopathy Disability 5/9/2008 4/13/2010 Physician United States
Primary
Secondary
Mesenteric Vein Thrombosis Other Serious 4/10/2008 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 6/16/2008 61 Female 4/13/2010 Physician United States
Primary
Secondary
Intestinal Haemorrhage Hospitalization 3/14/2008 4/13/2010 Physician United States
Primary
Secondary
T-cell Lymphoma Hospitalization 11/30/2008 70 Male 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/26/2008 4/20/2010 Physician United States
Primary
Secondary
Wernicke's Encephalopathy Disability 5/9/2008 4/20/2010 Physician United States
Primary
Secondary
Intestinal Haemorrhage Hospitalization 3/14/2008 4/20/2010 Physician United States
Primary
Secondary
T-cell Lymphoma Hospitalization 11/30/2008 70 Male 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Death 4/23/2010 United States
Primary
Secondary
Drug Toxicity Other Serious 4/23/2010 United States
Primary
Secondary
Drug Toxicity Death 4/23/2010 United States
Primary
Secondary
T-cell Lymphoma Hospitalization 5/9/2008 4/30/2010 Physician United States
Primary
Secondary
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/10/2010 34 Female 6/4/2010 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 5/10/2010 34 Female 6/8/2010 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 5/10/2010 34 Female 6/15/2010 Physician Italy
Primary
Secondary
Concomitant
Rash Other Serious 12/1/2003 67 Female 129 lb 7/7/2010 Other Health Professional Japan
Primary
Concomitant
Zygomycosis Other Serious 10/23/2007 16 Female 156 lb 7/30/2010 Physician United States
Primary
Secondary
Cerebral Ischaemia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 7/30/2010 Physician United States
Primary
Secondary
Lipase Increased Other Serious 7/30/2010 Physician United States
Primary
Secondary
Hypocalcaemia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Depressed Level Of Consciousness Other Serious 7/30/2010 Physician United States
Primary
Secondary
Hypophosphataemia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Aspartate Aminotransferase Increased Other Serious 7/30/2010 Physician United States
Primary
Secondary
Myalgia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Syncope Other Serious 7/30/2010 Physician United States
Primary
Secondary
Caecitis Other Serious 7/30/2010 Physician United States
Primary
Secondary
Hypoalbuminaemia Other Serious 7/30/2010 Physician United States
Primary
Secondary
Urinary Bladder Haemorrhage Hospitalization 4/30/2009 55 Male 8/6/2010 Physician Italy
Primary
Secondary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 4/30/2009 55 Male 8/18/2010 Physician Italy
Primary
Secondary
Concomitant
Toothache Hospitalization 3/23/2008 19 Female 143 lb 9/28/2010 Consumer
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 7/30/2010 55 Female 121 lb 9/29/2010 Consumer United Kingdom
Primary
Concomitant
Zygomycosis Other Serious 10/23/2007 16 Female 156 lb 10/5/2010 Physician United States
Primary
Secondary
Somnolence Hospitalization 6/16/2010 61 Male 10/21/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 12/12/2006 64 Female 154 lb 11/9/2010 Physician Germany
Primary
Concomitant
Neurotoxicity Hospitalization 7/1/2007 70 Female 150 lb 11/9/2010 Physician Germany
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 5/1/2008 27 Male 11/30/2010
Primary
Secondary
Acute Graft Versus Host Disease Other Serious Female 2/11/2011 Physician Japan
Primary
Secondary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Other Serious 12 2/15/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Life Threatening 10/7/2009 47 Female 126 lb 2/16/2011 Physician France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/17/2011 Physician United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 4/30/2009 55 Male 3/1/2011 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 3/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 17 Male 3/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 4/14/2011 Physician United Kingdom
Primary
Secondary
Leukaemia Recurrent Death 10/12/2011 2 Male 30 lb 10/16/2012 Physician De
Primary
Secondary
Concomitant
Crohn's Disease Other Serious 19 Female 8/29/2012 Physician Us
Primary
Secondary
Viral Pharyngitis Other Serious 12/2005 Male 9/7/2012 Lawyer Us
Primary
Concomitant
Skin Infection Hospitalization 2012 10 Female 99 lb 12/20/2012 Consumer Us
Primary
Secondary
Concomitant
Death Death Female 10/3/2012 Physician Us
Primary
Concomitant
Exposure During Pregnancy Other Serious Female 11/5/2012 Physician Mx
Primary
Secondary
Off Label Use Life Threatening 9/21/2012 2 Male 23 lb 11/20/2012 Consumer De
Primary
Secondary
Off Label Use Other Serious 9/21/2012 2 Male 23 lb 8/16/2013 Other Health Professional De
Primary
Secondary
Urinary Tract Infection Death Female 11/6/2012 Physician Mx
Primary
Secondary
Underweight Congenital Anomaly 11/2/2012 Other Health Professional Mx
Primary
Secondary
Sepsis Hospitalization 11/22/2012 0 Male 16 lb 12/3/2012 Physician Us
Primary
Secondary
Thrombocytopenia Hospitalization 10/22/2012 13 Male 12/21/2012 Physician Us
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 12/12/2012 11 Male 2/20/2013 Physician Us
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/27/2012 65 Female 137 lb 6/6/2013 Physician De
Primary
Secondary
Concomitant
Infection Death NotSpecified 1/30/2013 Physician It
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 12/30/2012 4 Male 2/24/2013 Physician Us
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/22/2013 7 Male 8/28/2013 Other Health Professional Ca
Primary
Secondary
Toxicity To Various Agents Death NotSpecified 4/10/2013 Physician It
Primary
Secondary
Concomitant
Toxicity To Various Agents Death NotSpecified 4/10/2013 Physician It
Primary
Secondary
Toxicity To Various Agents Death NotSpecified 4/10/2013 Physician It
Primary
Secondary
Toxicity To Various Agents Death NotSpecified 4/10/2013 Physician It
Primary
Secondary
Concomitant
Toxicity To Various Agents Death NotSpecified 4/10/2013 Physician It
Primary
Secondary
Concomitant
Toxicity To Various Agents Death NotSpecified 4/10/2013 Physician It
Primary
Secondary
Toxicity To Various Agents Death NotSpecified 4/10/2013 Physician It
Primary
Secondary
Toxicity To Various Agents Death NotSpecified 4/10/2013 Physician It
Primary
Secondary
Vomiting Other Serious NotSpecified 4/22/2013 Physician Fr
Primary
Secondary
Treatment Failure Other Serious NotSpecified 5/13/2013 Other Health Professional Us
Primary
Secondary
Pulmonary Toxicity Other Serious 59 Male 6/28/2013 Other Health Professional Us
Primary
Secondary
Renal Impairment Other Serious 17 Male 7/2/2013 Physician Gb
Primary
Secondary
Concomitant
Tonic Clonic Movements Hospitalization 10 Male 7/3/2013 Other Health Professional Cn
Primary
Secondary
Rectal Adenocarcinoma Death 53 NotSpecified 7/2/2013 Physician Es
Primary
Secondary
Concomitant
Endometrial Cancer Death 65 Female 7/3/2013 Physician Es
Primary
Secondary
Concomitant

Drug Data