Fludarabine Phosphate combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Death 5/9/2005 65 Male 2/28/2006 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 10/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 62 Female 10/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 10/20/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Infection Other Serious 62 Female 5/21/2007
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 25 Male 6/14/2007 Physician Australia
Primary
Secondary
Concomitant
Drug Toxicity Death 64 Male 6/16/2007 Italy
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 69 Female 8/16/2007
Primary
Secondary
Pneumonia Death 61 Male 10/10/2007 Physician United States
Primary
Concomitant
Nausea Other Serious 8/28/2007 52 Female 119 lb 10/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 10/18/2007 United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 12/1/2005 59 Male 10/22/2007 Physician Netherlands
Primary
Concomitant
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 4/1/2005 62 Female 10/23/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 10/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 10/30/2007 United Kingdom
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 70 Female 11/1/2007
Primary
Secondary
Concomitant
Nausea Other Serious 8/28/2007 52 Female 119 lb 10/30/2007 United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 62 Female 10/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 8/28/2007 52 Female 119 lb 11/8/2007 Other Health Professional United Kingdom
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 11/5/2007 Switzerland
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 11/12/2007 United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 11/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 11/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2005 62 Female 12/21/2007 United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 4/1/2005 62 Female 12/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 12/19/2007 Germany
Primary
Secondary
Viral Infection Life Threatening 4/1/2005 62 Female 12/28/2007 United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 62 Female 12/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 1/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 64 Female 1/24/2008 Physician United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 62 Female 1/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 25 Male 1/15/2008 Australia
Primary
Secondary
Vertigo Death 58 Male 3/29/2008 Physician Germany
Primary
Secondary
Stem Cell Transplant Other Serious 49 Female 4/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Autoimmune Neutropenia Other Serious 49 Female 5/7/2008 United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 1/1/2004 Male 5/15/2008 Other Health Professional Germany
Primary
Secondary
Neutropenia Other Serious 49 Female 5/16/2008 United Kingdom
Primary
Secondary
Autoimmune Neutropenia Other Serious 49 Female 5/29/2008 United Kingdom
Primary
Secondary
Pulmonary Sepsis Life Threatening 6/1/2004 51 Male 7/7/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious Female 9/11/2008 Physician Hungary
Primary
Secondary
Pneumonia Other Serious Female 9/11/2008 Physician Hungary
Primary
Secondary
Acute Myeloid Leukaemia Death 56 Female 9/19/2008 Italy
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 56 Female 275 lb 9/19/2008 Consumer United States
Primary
Concomitant
Pneumonia Death 49 Male 9/18/2008 Physician Hungary
Primary
Secondary
Pneumonia Death 66 Female 9/19/2008 Physician Hungary
Primary
Secondary
Respiratory Failure Other Serious 51 Male 7/19/2008 Other Health Professional Thailand
Primary
Secondary
Myelodysplastic Syndrome Disability 5/2/2007 67 Female 10/9/2008 Physician Canada
Primary
Secondary
Chronic Lymphocytic Leukaemia Death 12/13/2007 72 11/10/2008 Physician Netherlands
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 11/3/2006 65 Male 11/14/2008 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 4/7/2008 56 Male 11/14/2008 Consumer United States
Primary
Concomitant
Colitis Hospitalization 8/1/2007 26 Female 11/21/2008 Other Health Professional Spain
Primary
Concomitant
Leukaemia Other Serious 5/10/2008 69 Male 11/25/2008 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 3/1/2007 Female 11/26/2008 Other Health Professional Germany
Primary
Concomitant
Skin Nodule Other Serious 1/1/2006 36 Female 12/1/2008 Other Health Professional Germany
Primary
Concomitant
Nervous System Disorder Other Serious 12 Female 11/27/2008 Physician United States
Primary
Secondary
Stem Cell Transplant Other Serious 12 Female 12/2/2008 Physician United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 11/3/2006 65 Male 12/17/2008 Consumer United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 6/1/2008 Female 12/24/2008 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/8/2008 Male 12/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Stem Cell Transplant Other Serious 12 Female 1/6/2009 Physician United States
Primary
Secondary
Septic Shock Hospitalization 55 Male 1/20/2009
Primary
Secondary
Concomitant
Pancytopenia Death 1/1/2007 72 2/19/2009 Physician Netherlands
Primary
Secondary
Concomitant
Pyrexia Other Serious 63 Male 2/19/2009 Other Health Professional Italy
Primary
Secondary
Pancytopenia Death 1/1/2007 72 2/19/2009 Physician Netherlands
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 63 Male 2/25/2009 Italy
Primary
Secondary
Colitis Ulcerative Life Threatening 8/1/2007 26 Female 3/6/2009 Spain
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 63 Male 3/6/2009 Italy
Primary
Secondary
Neuropathy Peripheral Hospitalization 1/1/2008 12 Female 3/6/2009 Other Health Professional United States
Primary
Secondary
Myelodysplastic Syndrome Death 1/14/2008 Male 4/2/2009 Consumer United Kingdom
Primary
Secondary
Pulmonary Tuberculosis Other Serious 2/1/2006 59 Unknown 3/30/2009 Italy
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 59 Female 4/22/2009 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious Female 105 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Sudden Cardiac Death Other Serious 5/19/2009 Consumer United Kingdom
Primary
Secondary
Infection Other Serious 5/19/2009 Physician United Kingdom
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Death 59 Male 5/18/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Infection Other Serious 5/28/2009 Physician United Kingdom
Primary
Secondary
Sudden Cardiac Death Other Serious 5/29/2009 Consumer United Kingdom
Primary
Secondary
Septic Shock Death 69 Male 6/22/2009 Physician Czech Republic
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2006 69 Male 6/26/2009 Other Health Professional Czech Republic
Primary
Secondary
Leukoencephalopathy Hospitalization 69 Male 6/26/2009 Czech Republic
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2008 43 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2006 69 Male 6/30/2009 Other Health Professional Czech Republic
Primary
Secondary
Septic Shock Death 69 Male 6/30/2009 Physician Czech Republic
Primary
Secondary
Leukoencephalopathy Hospitalization 69 Male 7/9/2009 Czech Republic
Primary
Secondary
Concomitant
Toxoplasmosis Other Serious 40 Male 7/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 84 Male 8/17/2009 Consumer Turkey
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/14/2009 Other Health Professional United States
Primary
Secondary
Viral Infection Life Threatening 9/17/2008 70 Male 10/14/2009 Japan
Primary
Secondary
Concomitant
Viral Infection Life Threatening 9/17/2008 70 Male 11/3/2009 Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Death 10/8/2008 88 Male 12/2/2009 Physician Japan
Primary
Concomitant
Drug Effect Decreased Death 8/1/2009 66 Female 12/18/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 12/8/2009 29 Female 1/13/2010 Physician Italy
Primary
Secondary
Cardiac Failure Death 3/9/2010 Physician Germany
Primary
Secondary
Concomitant
Breast Cancer Other Serious 2/1/2010 Female 3/22/2010 Consumer Spain
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/25/2010 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Other Serious 52 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/31/2010 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Other Serious 52 Male 4/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 62 Female 4/5/2010 Other Health Professional United States
Primary
Concomitant
Breast Cancer Other Serious 1/28/2010 58 Female 5/10/2010 Consumer Spain
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 3/1/2010 77 Male 5/10/2010 Physician United Kingdom
Primary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Leukoencephalopathy Death 2/1/2009 71 Female 110 lb 5/13/2010 Physician Netherlands
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/23/2008 72 Male 7/2/2010 Other Health Professional Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 50 Female 7/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 64 Female 7/23/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of The Cervix Other Serious 50 Female 7/30/2010 Other Health Professional Germany
Primary
Secondary
Staphylococcal Infection Other Serious 49 Female 8/11/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Septic Shock Other Serious 59 Male 8/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 70 Male 9/17/2010 Physician Japan
Primary
Concomitant
Muscle Spasms Disability 58 Female 10/29/2010 Consumer United Kingdom
Primary
Concomitant
Ileus Other Serious 12/17/2010 Other Health Professional Serbia
Primary
Secondary
Ileus Other Serious 12/30/2010 Other Health Professional Serbia
Primary
Secondary
Precursor T-lymphoblastic Lymphoma/leukaemia Other Serious 12 2/15/2011 Physician Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 3/1/2010 74 Male 3/30/2011 Other Health Professional France
Primary
Secondary
Thrombocytopenia Other Serious 75 Female 3/30/2011 Physician United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Other Serious 11/18/2010 73 Male 209 lb 4/20/2011 Physician United Kingdom
Primary
Secondary
Cerebral Artery Embolism Life Threatening 2/25/2009 60 Male 4/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Death 11 Male 5/24/2011 Other Health Professional Japan
Primary
Secondary
Myelodysplastic Syndrome Other Serious 11/18/2010 73 Male 209 lb 6/8/2011 Physician United Kingdom
Primary
Secondary
Herpes Zoster Hospitalization 2/28/2009 59 Male 141 lb 6/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Off Label Use Other Serious 26 Female 6/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 1 Female 7/11/2011 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 1 Female 7/11/2011 Consumer United Kingdom
Primary
Secondary
Haematotoxicity Other Serious 2 Male 7/11/2011 Consumer United Kingdom
Primary
Secondary
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Disease Progression Hospitalization 2/10/2009 57 Female 4/16/2011 Other Health Professional Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 11/18/2010 73 Male 209 lb 8/25/2011 Physician United Kingdom
Primary
Secondary
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Gaze Palsy Death 60 Male 9/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 9/15/2008 9/29/2011 Physician Denmark
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 34 Female 10/19/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 9/15/2008 10/24/2011 Consumer Denmark
Primary
Secondary
Concomitant
Infection Other Serious 10 Male 11/9/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 9/15/2008 11/16/2011 Physician Denmark
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/17/2011 Other Health Professional Canada
Primary
Secondary
Renal Failure Disability 4/18/2008 70 Female 12/9/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 12/20/2011 Other Health Professional Netherlands
Primary
Secondary
Thrombocytopenia Other Serious 11 Male 12/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data