Fluconazole combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Systemic Candida Other Serious Female 1/25/2006 Physician France
Primary
Secondary
Renal Failure Other Serious 10/17/2005 24 Female 132 lb 2/9/2006 Physician France
Primary
Secondary
Neutropenia Other Serious 1/21/2005 53 Male 2/16/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/15/2005 64 Male 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Systemic Candida Other Serious 10/17/2005 24 Female 132 lb 4/21/2006 Physician France
Primary
Secondary
Pancytopenia Other Serious 1/1/2005 8 Male 5/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Systemic Candida Other Serious 10/17/2005 24 Female 110 lb 5/15/2006 Physician France
Primary
Secondary
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/17/2005 24 Female 110 lb 6/30/2006 Physician France
Primary
Secondary
Febrile Neutropenia Hospitalization 6/5/2006 62 Male 7/19/2006 Physician Italy
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/18/2006 49 Male 146 lb 7/28/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/5/2006 62 Male 7/27/2006 Physician Italy
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/19/2006 Male 8/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/26/2006 Male 157 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/26/2006 Male 157 lb 9/8/2006 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/9/2005 Male 164 lb 10/5/2006 Physician Australia
Primary
Concomitant
Weight Increased Required Intervention 9/18/2006 Male 36 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Multi-organ Failure Hospitalization 4/25/2006 Male 157 lb 10/31/2006 Physician United States
Primary
Secondary
Concomitant
Thrombosis 9/29/2006 Pharmacist United States
Primary
Concomitant
Central Nervous System Lymphoma Hospitalization 70 Female 12/1/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/30/2006 63 Male 229 lb 1/22/2007 Physician United States
Primary
Secondary
Concomitant
Heart Rate Abnormal Disability 2/16/2006 43 Female 2/17/2007 Australia
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 2/20/2007 Consumer Australia
Primary
Secondary
Thrombocytopenia Other Serious 2/20/2007 Consumer Australia
Primary
Secondary
Neutropenic Sepsis Other Serious 12/20/2006 18 Male 2/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/22/2007 Australia
Primary
Secondary
Stem Cell Transplant Death Unknown 2/22/2007 Australia
Primary
Secondary
Neutropenic Sepsis Death 12/20/2006 18 Male 2/20/2007 United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 12/20/2006 18 Male 2/24/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 12/20/2006 18 Male 3/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 3/30/2007 Physician Czech Republic
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 12/20/2006 18 Male 4/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 11 Male 4/5/2007 India
Primary
Concomitant
Grand Mal Convulsion Other Serious 11 Male 4/17/2007 India
Primary
Concomitant
Tachycardia Hospitalization 1/20/2007 62 Female 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Venous Haemorrhage Death 42 Male 6/1/2007 Greece
Primary
Secondary
Concomitant
Peroneal Nerve Palsy Hospitalization 6/18/2005 15 Female 108 lb 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 6/18/2005 15 Female 6/13/2007 United Kingdom
Primary
Secondary
Concomitant
Prophylaxis Hospitalization 6/18/2005 15 Female 6/13/2007 United Kingdom
Primary
Secondary
Concomitant
Peroneal Nerve Palsy Hospitalization 6/18/2005 15 Female 108 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 6/23/2007 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 6/21/2007 Czech Republic
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 1/1/2002 71 Male 9/4/2007
Primary
Concomitant
Myelodysplastic Syndrome Death 54 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 61 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 79 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/12/2007 70 Male 196 lb 10/1/2007 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 8/16/2007 Female 10/15/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 64 Male 176 lb 10/18/2007
Primary
Secondary
Concomitant
Pericarditis Fungal Other Serious 11/11/2005 3 Female 10/23/2007
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 8/16/2007 Female 10/24/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2007 Female 11/14/2007 Pharmacist United Kingdom
Primary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/15/2008 Consumer United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/22/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/21/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 5 Female 3/1/2008 Consumer Hong Kong
Primary
Secondary
Concomitant
Palpitations Hospitalization 61 Female 3/11/2008 Physician United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 3/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pancytopenia Hospitalization 12/21/2007 Female 3/21/2008 Physician Australia
Primary
Secondary
Concomitant
Movement Disorder Hospitalization 1/9/2008 13 Male 128 lb 3/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 13 Male 3/18/2008 United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 3/20/2008 United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 3/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sputum Culture Positive Hospitalization 3/4/2008 60 Male 154 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Venoocclusive Disease Hospitalization 2 Male 3/31/2008
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/9/2008 13 Male 128 lb 4/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Movement Disorder Hospitalization 1/9/2008 13 Male 128 lb 4/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/14/2008 13 Male 4/2/2008 United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 1/14/2008 13 Male 4/1/2008 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/9/2008 13 Male 128 lb 4/4/2008 United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 2/7/2008 60 Male 160 lb 4/8/2008 Physician Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/21/2007 Male 4/15/2008 Other Health Professional France
Primary
Secondary
Hypercalcaemia Hospitalization 4/16/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 3 Female 4/15/2008 Physician United Kingdom
Primary
Concomitant
Protein Total Decreased Other Serious Male 176 lb 4/21/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Pneumonia Fungal Hospitalization 3 Male 4/23/2008 Japan
Primary
Concomitant
Pancytopenia Hospitalization 12/21/2007 Female 5/2/2008 Physician Australia
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 4/16/2008 52 Male 157 lb 5/21/2008 Physician Malaysia
Primary
Concomitant
T-cell Lymphoma Other Serious 11/1/2006 41 Male 7/10/2008 Netherlands
Primary
Secondary
Concomitant
T-cell Lymphoma Recurrent Other Serious 8/1/2006 32 Female 7/11/2008 Netherlands
Primary
Secondary
Concomitant
T-cell Lymphoma Recurrent Other Serious 8/1/2006 32 Female 7/14/2008 Netherlands
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/21/2007 Female 7/23/2008 Physician Australia
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 8/7/2008 Physician Belgium
Primary
Concomitant
Thrombosis Other Serious 7/12/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/13/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/26/2008 59 Male 198 lb 8/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 8/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 8/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 8/29/2008 Physician Belgium
Primary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 9/11/2008 Physician Belgium
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/13/2008 Female 9/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Fungaemia Other Serious 57 Female 9/26/2008 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/13/2008 Female 10/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/2/2008 Female 10/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 9/2/2008 16 Male 145 lb 10/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Infection Life Threatening 38 Female 10/30/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/13/2008 Female 11/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 10/2/2008 Female 11/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Death 68 Male 11/19/2008 Italy
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 47 Female 11/19/2008 Italy
Primary
Secondary
Concomitant
Anaemia Other Serious 51 Male 11/17/2008 Physician Italy
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 38 Female 11/17/2008 Physician Italy
Primary
Secondary
Concomitant
Neutropenia Other Serious 68 Male 11/17/2008 Physician Italy
Primary
Secondary
Concomitant
Neutropenia Other Serious 31 Male 11/17/2008 Physician Italy
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 47 Female 11/17/2008 Physician Italy
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 49 Male 8/7/2008 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 12/1/2008 Physician Germany
Primary
Secondary
Concomitant
Systemic Candida Other Serious 2 Male 12/2/2008
Primary
Secondary
Serotonin Syndrome Other Serious 73 Female 12/4/2008
Primary
Secondary
Serotonin Syndrome Other Serious 46 Female 12/4/2008
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/24/2008 16 Male 145 lb 11/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/24/2008 16 Male 145 lb 12/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 12/21/2008 4 Male 44 lb 1/7/2009 Physician Germany
Primary
Secondary
Concomitant
Puncture Site Infection Hospitalization 12/21/2008 4 Male 44 lb 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Urticaria Other Serious 12/11/2008 17 Female 1/27/2009 Consumer France
Primary
Secondary
Concomitant
Vomiting Other Serious 8/24/2008 16 Male 145 lb 1/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/27/2009 Female 2/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/27/2009 Female 2/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Clostridium Difficile Colitis 22 Female 2/19/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8/24/2008 16 Male 145 lb 2/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Leukoencephalopathy Death Female 2/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Death 5/1/2008 64 Female 3/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 7/12/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/22/2008 56 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Sinus Arrhythmia Hospitalization 3/21/2009 3/23/2009 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 2/24/2009 Female 3/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vocal Cord Paralysis Other Serious 14 Male 3/24/2009 Physician India
Primary
Secondary
Febrile Neutropenia Hospitalization 9/13/2007 59 Female 4/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Amoebiasis Hospitalization 3/2/2008 52 Male 4/23/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 84 lb 4/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/15/2009 11 Male 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 5/4/2009 Female 5/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/14/2009 62 Male 5/21/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/5/2009 Female 5/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Life Threatening 3/23/2009 Female 6/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/5/2009 Female 6/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Other Serious 38 Female 6/16/2009 Physician Italy
Primary
Secondary
Concomitant

Drug Data