Cyclophosphamide combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 56 Male 10/27/2005 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 9 Male 12/28/2005 France
Primary
Secondary
Anaphylactic Shock Other Serious 10/25/2005 39 Female 1/2/2006 Physician France
Primary
Secondary
Neutropenia Other Serious 70 Female 1/2/2006 Other Health Professional Australia
Primary
Concomitant
Sudden Death Death 58 Female 123 lb 1/2/2006 Physician Poland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/9/2003 51 Male 12/30/2005 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/23/2004 72 Female 12/22/2005 Other Health Professional Australia
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/7/2004 62 Male 1/5/2006 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 9/1/2005 63 Female 196 lb 1/5/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/18/2001 53 Male 95 lb 1/9/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/31/2005 50 Male 200 lb 1/6/2006 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/6/2006 Female 1/10/2006 Other Health Professional United States
Primary
Secondary
Unresponsive To Verbal Stimuli Other Serious 67 Male 1/17/2006 Consumer United States
Primary
Secondary
Sudden Death Death 58 Female 123 lb 1/13/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 23 Female 1/16/2006 Physician Turkey
Primary
Secondary
White Blood Cell Count Decreased Required Intervention 72 Male 1/13/2006 Japan
Primary
Secondary
Respiratory Distress Hospitalization 12/12/2005 72 Male 1/12/2006 France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 10/12/2005 57 Male 151 lb 10/28/2005 Pharmacist United States
Primary
Secondary
Sudden Death Death 8/9/2005 58 Female 123 lb 1/19/2006 Physician Poland
Primary
Secondary
Concomitant
Neuroendocrine Carcinoma Of The Skin Other Serious 8/1/2004 51 Female 1/25/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 12/9/2005 72 Male 163 lb 1/20/2006 Physician France
Primary
Secondary
Concomitant
Pancreatitis Necrotising Hospitalization 9/30/2005 7 Female 53 lb 1/23/2006 United States
Primary
Concomitant
Premature Labour Hospitalization 4/22/2004 Female 1/23/2006 Australia
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Life Threatening 7/21/2004 82 Male 1/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 37 Female 1/24/2006 Physician United States
Primary
Concomitant
Rash Other Serious 7/7/2004 Male 1/31/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/11/2005 80 Female 143 lb 1/26/2006 Poland
Primary
Concomitant
Vomiting Hospitalization 12/20/2005 Male 1/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 33 Female 1/27/2006 Physician Taiwan, Province Of China
Primary
Secondary
Respiratory Disorder Other Serious 17 Male 2/2/2006 Other Health Professional Ireland
Primary
Secondary
Vomiting Death Female 1/31/2006 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Death 6/19/2002 61 Female 1/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pseudobulbar Palsy Other Serious 17 Male 2/3/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Other Serious 1/4/2006 5 Female 35 lb 2/3/2006 Physician United States
Primary
Secondary
Concomitant
Hepatic Failure Death 12/5/2003 61 Male 2/1/2006 Physician Japan
Primary
Concomitant
Haemolytic Anaemia Hospitalization 64 Female 2/3/2006 Physician France
Primary
Concomitant
Agranulocytosis Other Serious Unknown 2/6/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Death 9/18/2005 60 Male 2/3/2006 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/9/2005 79 Male Pharmacist United States
Primary
Secondary
Shift To The Left Other Serious 1/23/2006 68 Male 198 lb 2/8/2006 Physician Australia
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/11/2006 11 Male 77 lb 2/14/2006 Consumer United States
Primary
Concomitant
Syncope Hospitalization 2/12/2006 63 Male 229 lb 2/15/2006 Other Health Professional United States
Primary
Secondary
Pyrexia Other Serious 6/27/2005 57 Male 143 lb 2/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 6/16/2005 63 Male 2/8/2006 United States
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Life Threatening 7/21/2004 82 Male 2/10/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Hospitalization 52 Male 2/10/2006 United Kingdom
Primary
Secondary
Concomitant
Surgery Other Serious 6/27/2005 Female 2/18/2006 Spain
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/26/2006 58 Female 2/13/2006 Physician Australia
Primary
Secondary
Respiratory Failure Hospitalization 52 Male 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 4/1/1998 16 Male 2/15/2006 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/17/2005 43 2/15/2006 Physician Germany
Primary
Concomitant
Granulocytopenia Life Threatening 11/1/2005 Male 190 lb 2/16/2006 Physician Germany
Primary
Concomitant
Neutropenia Other Serious 1/21/2005 53 Male 2/16/2006 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 9/27/2005 66 Female 2/16/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/7/2004 67 Female 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/15/2005 64 Male 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 73 Female 2/17/2006 Physician France
Primary
Concomitant
Rhabdomyoma Other Serious 73 Male 2/24/2006 Consumer United States
Primary
Secondary
Haemoglobin Decreased Hospitalization 1/23/2006 59 Male 187 lb 2/17/2006 Australia
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/27/2005 67 Male 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 2/21/2006 Physician Spain
Primary
Secondary
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/22/2006 Physician France
Primary
Secondary
Concomitant
Tongue Paralysis Life Threatening 17 Male 2/15/2006
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/23/2004 72 Female 2/22/2006 Other Health Professional Australia
Primary
Secondary
B-cell Lymphoma Other Serious 12/1/2005 42 Female 2/22/2006 Other Health Professional United States
Primary
Concomitant
Plasmacytoma Other Serious 54 Male 2/22/2006 Physician United States
Primary
Secondary
General Physical Health Deterioration Hospitalization 11/5/2005 40 Female 154 lb 2/24/2006 France
Primary
Secondary
Cerebral Haemorrhage Death 2/24/2006 Physician Spain
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 67 Female 2/27/2006 Physician France
Primary
Concomitant
Tachycardia Life Threatening Male 2/27/2006 Physician Germany
Primary
Concomitant
Subarachnoid Haemorrhage Death 2/7/2006 62 Unknown 121 lb 2/27/2006 Physician Spain
Primary
Secondary
Concomitant
Pseudobulbar Palsy Other Serious 17 Male 3/1/2006 Physician Ireland
Primary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 24 Male 165 lb 3/6/2006 Physician Norway
Primary
Concomitant
Staphylococcal Infection Hospitalization 11/23/2005 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia 27 Male 1/23/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 2/1/1999 41 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Coma Death 12/13/2005 50 Female 128 lb 3/2/2006 Physician Spain
Primary
Concomitant
Febrile Neutropenia Death Male 3/2/2006 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2004 63 Female 112 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 4/1/1998 16 Male 3/1/2006 Physician Spain
Primary
Secondary
Concomitant
Rash Papular Hospitalization 2/20/2006 19 Male 3/7/2006 Physician Mexico
Primary
Concomitant
Rash Papular Hospitalization 2/20/2006 19 Male 3/7/2006 Physician Mexico
Primary
Concomitant
Liver Disorder Other Serious 3/1/2006 Physician Japan
Primary
Concomitant
Therapy Non-responder Death 66 Male 3/4/2006 United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/17/2005 64 Male 119 lb 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Death 2/7/2006 62 Unknown 121 lb 3/3/2006 Physician Spain
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 10/26/2005 57 Male 101 lb 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 6/4/2005 14 Male 3/6/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 60 Female 3/7/2006 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/2004 68 Male 152 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/4/2004 74 Female 115 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 5/9/2005 65 Male 2/28/2006 Physician United States
Primary
Concomitant
Restlessness Hospitalization 2/24/2006 Male 3/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 11/1/2005 58 Female 3/8/2006 Physician United Kingdom
Primary
Concomitant
Skin Exfoliation Hospitalization 12/15/2005 61 Male 3/15/2006 Consumer Netherlands
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/15/2006 United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 60 Male 3/13/2006 Physician France
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/13/2005 75 Male 3/10/2006 Physician Japan
Primary
Concomitant
Rash Pustular Hospitalization 2/24/2006 78 Male 199 lb 3/10/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 52 Male 3/10/2006 Physician United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 2/1/2006 24 Male 165 lb 3/21/2006 Physician Norway
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 12/1/2005 75 Female 176 lb 3/15/2006 Physician France
Primary
Concomitant
Skin Exfoliation Hospitalization 12/15/2005 61 Male 3/15/2006 Physician Netherlands
Primary
Secondary
Concomitant
Coma Death 12/13/2005 50 Female 128 lb 3/14/2006 Physician Spain
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 12/9/2005 71 Male 3/9/2006 France
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/6/2004 57 Male 3/17/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2005 83 Female 99 lb 3/17/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/24/2006 United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 48 Female 3/15/2006
Primary
Concomitant
Pyrexia Hospitalization 71 Male 3/20/2006 Physician France
Primary
Concomitant
Trismus Hospitalization 8/2/2005 14 Male 3/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/1/2005 Male 3/27/2006 Consumer
Primary
Concomitant
Polyuria Other Serious 13 Female 3/17/2006 United States
Primary
Concomitant
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Subileus Required Intervention 7/19/2005 59 Female 3/22/2006 Physician Portugal
Primary
Concomitant
Sepsis Death 55 Female 3/21/2006 Physician Korea, Democratic People's Republic Of
Primary
Secondary
Sepsis Death 55 Female 3/22/2006 Physician Korea, Democratic People's Republic Of
Primary
Secondary
Pyrexia Death 32 Female 3/24/2006 Physician South Africa
Primary
Secondary
Optic Neuritis Disability 1/15/2005 65 Female 121 lb 3/15/2006 Physician France
Primary
Concomitant
Therapy Non-responder Hospitalization 66 Male 3/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 65 Male 3/27/2006 Physician France
Primary
Concomitant
Shock Life Threatening 8/3/2005 69 Male 154 lb 3/27/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 65 Male 3/29/2006 Physician France
Primary
Concomitant
Therapy Non-responder Death 66 Male 3/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Drug Toxicity Death 3/30/2006 Other Health Professional Japan
Primary
Secondary
Pneumonia Required Intervention 3/30/2006 Other Health Professional Japan
Primary
Secondary
Pneumonia Required Intervention 3/30/2006 Other Health Professional Japan
Primary
Secondary
Pneumonia Required Intervention 3/30/2006 Other Health Professional Japan
Primary
Secondary
Drug Toxicity Death 3/30/2006 Other Health Professional Japan
Primary
Secondary
Radial Nerve Lesion Other Serious 3/1/2006 65 Male 3/30/2006 Physician Canada
Primary
Concomitant
Hypogammaglobulinaemia Death 75 Male 3/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Hospitalization Male 3/30/2006 Physician France
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 4/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/3/2006 77 Male 4/6/2006 Other Health Professional United States
Primary
Secondary
Sepsis Required Intervention Unknown 4/4/2006 Other Health Professional Japan
Primary
Secondary
Shock Death 8/2/2005 70 Male 187 lb 4/4/2006 Physician Italy
Primary
Secondary
Concomitant
Surgical Procedure Repeated Other Serious 64 Female 4/4/2006 Physician Germany
Primary
Concomitant
Rhabdomyoma Other Serious 73 Male 4/14/2006 Consumer United States
Primary
Secondary
Spinal Cord Haemorrhage Life Threatening 7/14/2004 67 Female 4/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 9/4/2004 Male 4/17/2006 Japan
Primary
Secondary
Concomitant
Superinfection Hospitalization Male 4/7/2006 Physician France
Primary
Concomitant
Thrombosis Other Serious 2/15/2006 53 Male 172 lb 4/7/2006 Other Health Professional France
Primary
Secondary
Neutropenia Hospitalization 52 Male 4/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 3/15/2006 38 Female 176 lb 4/11/2006 Physician Australia
Primary
Secondary
Concomitant
Urinary Incontinence Death 19 Male 4/7/2006 Other Health Professional Spain
Primary
Secondary
Dysphasia Death 12/13/2005 50 Female 128 lb 4/12/2006 Physician Spain
Primary
Concomitant

Drug Data