Thioguanine combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Peripheral Motor Neuropathy Other Serious 1/4/2006 5 Female 35 lb 2/3/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 16 Male 6/2/2006 Physician Canada
Primary
Secondary
Idiopathic Thrombocytopenic Purpura Other Serious 10 Female 6/3/2006 Physician Canada
Primary
Secondary
Blood Growth Hormone Decreased Other Serious 12 Female 8/4/2006 Other Health Professional United States
Primary
Secondary
Epiphyseal Disorder Other Serious 15 Male 8/4/2006 Other Health Professional United States
Primary
Secondary
Neurotoxicity Other Serious 15 Female 10/7/2006 United States
Primary
Concomitant
Metastasis Death 11 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Female 3/5/2007
Primary
Secondary
Metastasis Death 13 Female 3/5/2007
Primary
Secondary
Metastasis Death 12 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Male 3/5/2007
Primary
Secondary
Peripheral Motor Neuropathy Required Intervention 1/4/2006 5 Female 35 lb 3/1/2007 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 15 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 13 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 11 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 15 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 12 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Pleural Fibrosis Disability 2/1/1994 29 Male 79 lb 6/26/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pleural Fibrosis Disability 2/1/1994 29 Male 79 lb 6/29/2007 Consumer United States
Primary
Secondary
Concomitant
Trichostasis Spinulosa Other Serious 6 Male 6/30/2007 Physician Australia
Primary
Secondary
Precocious Puberty Other Serious Female 9/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Glioma Death 15 Male 11/21/2007 Germany
Primary
Secondary
Glioma Death 13 Female 11/21/2007 Germany
Primary
Secondary
Nervous System Disorder Death 12 Male 11/21/2007 Physician Germany
Primary
Secondary
Glioma Death 11 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Stress Other Serious 28 Male 12/14/2007 Australia
Primary
Secondary
Vomiting Other Serious 2 Female 2/7/2008 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 11 Male 6/20/2008 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 6/26/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 6/30/2008 Consumer United States
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/9/2008 Consumer United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/15/2008 United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/16/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/17/2008 Consumer United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/17/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/25/2008 United Kingdom
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/28/2008 United Kingdom
Primary
Secondary
Rash Vesicular Death 2 Male 7/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Promyelocyte Count Increased Life Threatening 54 Male 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Viral Infection Death 2 Male 8/11/2008 United Kingdom
Primary
Secondary
Hepatic Encephalopathy Death 2 Male 8/14/2008 United Kingdom
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 8/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 54 Male 9/29/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 8/15/2008 United Kingdom
Primary
Secondary
Stem Cell Transplant Other Serious 30 Female 12/30/2008 Other Health Professional Netherlands
Primary
Secondary
Nuclear Magnetic Resonance Imaging Brain Abnormal Other Serious 16 Male 2/17/2009 Physician United States
Primary
Concomitant
Neurotoxicity Other Serious 16 Male 2/25/2009
Primary
Secondary
Neurotoxicity Hospitalization 16 Male 4/28/2009 Physician United States
Primary
Concomitant
Thymus Enlargement Required Intervention 14 Male 6/26/2009 Physician China
Primary
Secondary
Thymus Enlargement Other Serious 11 Female 6/26/2009 Other Health Professional China
Primary
Secondary
Thymus Enlargement Other Serious 15 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Thymus Enlargement Other Serious 12 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Thymus Enlargement Required Intervention 6 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Thymus Enlargement Required Intervention 9 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Hemiparesis Hospitalization 7/27/2008 13 Male 134 lb 8/5/2009 Pharmacist Belgium
Primary
Secondary
Concomitant
Transplant Other Serious 13 Male 7/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 13 Male 8/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 13 Male 8/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Transplant Other Serious 13 Male 8/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 13 Male 8/27/2009 Physician United Kingdom
Primary
Secondary
Staphylococcal Infection Other Serious 13 Male 8/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Tic Other Serious 13 Male 9/1/2009
Primary
Concomitant
Lipase Increased Other Serious 7/10/2009 3 Female 33 lb 9/29/2009 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 12 Male 10/15/2009 Other Health Professional Canada
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 7/10/2009 3 Female 33 lb 10/19/2009 Physician United States
Primary
Secondary
Concomitant
Insulin-like Growth Factor Decreased Other Serious 12 Female 11/17/2009 Other Health Professional United States
Primary
Secondary
Epiphysiolysis Other Serious 15 Male 11/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 10 Male 12/7/2009
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 13 Male 12/21/2009 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 17 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Burkitt's Leukaemia Hospitalization 13 Male 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 54 Male 1/8/2010 Consumer United Kingdom
Primary
Secondary
Pleural Effusion Hospitalization 1 Male 1/7/2010 Physician United States
Primary
Concomitant
Platelet Disorder Life Threatening 1/12/2005 11 Male 79 lb 1/18/2010 Consumer United Kingdom
Primary
Concomitant
Tic Other Serious 13 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Tic Other Serious 13 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Staphylococcal Bacteraemia Other Serious 13 Male 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Other Serious 17 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 7/10/2009 3 Female 33 lb 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 3/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Tic Other Serious 13 Male 3/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 3/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 3/19/2010 United Kingdom
Primary
Concomitant
Tic Other Serious Male 3/18/2010 United States
Primary
Concomitant
Vocal Cord Paralysis Hospitalization 2 Male 3/24/2010 Physician Australia
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 4/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Neurotoxicity Other Serious 12 Male 5/13/2010
Primary
Secondary
Vasculitis Hospitalization 7/27/2008 13 Male 6/6/2010 Belgium
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 4 Female 6/9/2010 Other Health Professional Canada
Primary
Secondary
White Blood Cell Count Increased Other Serious 4 Female 6/17/2010 Other Health Professional Canada
Primary
Secondary
Viith Nerve Paralysis Hospitalization 7/27/2008 13 Male 134 lb 8/25/2010 Pharmacist Belgium
Primary
Secondary
Concomitant
Viith Nerve Paralysis Hospitalization 7/27/2008 13 Male 134 lb 8/25/2010 Pharmacist Belgium
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 8/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Tic Required Intervention 13 Male 8/27/2010 United Kingdom
Primary
Secondary
Tic Other Serious 13 Male 9/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Tumour Lysis Syndrome Other Serious 13 Male 9/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 13 Male 9/6/2010 Belgium
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 9/3/2010 United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12 Male 9/23/2010
Primary
Secondary
Toothache Hospitalization 3/23/2008 19 Female 143 lb 9/28/2010 Consumer
Primary
Secondary
Concomitant
Tic Other Serious 13 Male 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Low Density Lipoprotein Increased Other Serious 7/10/2009 3 Female 33 lb 10/13/2010 Physician United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Life Threatening 7 Female 12/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Life Threatening 7 Female 12/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Other Serious 7 Female 12/29/2010 Other Health Professional Germany
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/17/2011 Physician United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 3/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 17 Male 3/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Death 3/3/2011 14 Female 90 lb 3/16/2011 Physician United States
Primary
Secondary
Concomitant
Ammonia Increased Life Threatening 3/18/2011 3 Male 6/17/2011 Consumer France
Primary
Secondary
Concomitant
Osteoporosis Other Serious 6/27/2011 Physician Germany
Primary
Secondary
Ischaemic Cerebral Infarction Hospitalization 4/18/2011 13 Female 96 lb 8/5/2011 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/30/2011 5 Female 31 lb 9/1/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 6/30/2011 5 Female 9/2/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Death 9/16/2011 Physician United States
Primary
Secondary
Cerebral Infarction Death 9/19/2011 Physician United States
Primary
Secondary
Off Label Use Death 9/20/2011 Physician United States
Primary
Secondary
Cerebral Infarction Death 9/22/2011 Physician United States
Primary
Secondary
Pneumocystis Jiroveci Infection Other Serious 10/13/2011 Physician France
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 10/3/2011 12 Female 99 lb 11/21/2011 Physician United States
Primary
Secondary
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Female 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Secondary Hypothyroidism Other Serious 4/18/2012 Physician Greece
Primary
Secondary
Infection Death 4/18/2012 Physician Greece
Primary
Secondary
Sepsis Life Threatening 5/17/2012 Female 124 lb 5/30/2012 Physician United States
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 5/31/2012 Physician Greece
Primary
Secondary
Candida Osteomyelitis Other Serious 5/24/2012 Consumer United States
Primary
Secondary
Complications Of Bone Marrow Transplant Death 5/31/2012 Physician Greece
Primary
Secondary
Hallucination Hospitalization 3/23/2012 9 Male 55 lb 8/3/2012 Physician France
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/3/2011 12 Female 99 lb 10/19/2012 Physician Us
Primary
Secondary

Drug Data