Mitoxantrone combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Aplasia Pure Red Cell Hospitalization 3/23/2006 Male 5/15/2006 Physician Hungary
Primary
Concomitant
West Nile Viral Infection Other Serious 57 Male 5/12/2006 United States
Primary
Secondary
Aplasia Pure Red Cell Hospitalization 3/23/2006 Male 6/7/2006 Physician Hungary
Primary
Concomitant
Pneumonia Death 6/15/2006 Austria
Primary
Secondary
Therapy Non-responder Hospitalization 1/1/2006 Female 108 lb 9/7/2006 Physician Portugal
Primary
Concomitant
Pneumonitis Other Serious 53 Male 6/6/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 1/1/2006 Female 108 lb 10/12/2006 Physician Portugal
Primary
Concomitant
Splenomegaly Hospitalization 1/1/2006 Female 108 lb 12/8/2006 Physician Portugal
Primary
Concomitant
Pancytopenia Other Serious 4/2/2007 Other Health Professional Italy
Primary
Secondary
Myelodysplastic Syndrome Life Threatening 2/21/2007 65 Female 4/11/2007 Other Health Professional United States
Primary
Concomitant
Superior Sagittal Sinus Thrombosis Other Serious 25 Male 151 lb 5/9/2007 Japan
Primary
Secondary
Concomitant
Superior Sagittal Sinus Thrombosis Life Threatening 25 Male 151 lb 6/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 10/25/2007 Physician Italy
Primary
Concomitant
Acute Myelomonocytic Leukaemia Death 68 Male 2/23/2008 Consumer United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 75 Female 2/23/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 58 2/26/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/27/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 2/27/2008 Consumer United Kingdom
Primary
Secondary
Therapeutic Response Decreased Death 68 Male 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Death 75 Female 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 58 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 8/27/2003 44 Female 134 lb 3/6/2008 Physician Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious Female 3/19/2008 Physician United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 2/20/2008 Female 4/1/2008 Physician United Kingdom
Primary
Concomitant
Bradycardia Other Serious 3/1/2008 7 Male 50 lb 5/2/2008 United Kingdom
Primary
Concomitant
Transplant Rejection Death 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Bacterial Sepsis Death 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Cancer Death 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatitis C Virus Test Other Serious 11/1/2005 68 Male 6/27/2008 Taiwan, Province Of China
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/1/2003 76 Female 8/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 44 Male 8/21/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Fungal Death 76 Female 8/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious Female 9/11/2008 Physician Hungary
Primary
Secondary
Pneumonia Other Serious Female 9/11/2008 Physician Hungary
Primary
Secondary
Pneumonia Death 49 Male 9/18/2008 Physician Hungary
Primary
Secondary
Pneumonia Death 66 Female 9/19/2008 Physician Hungary
Primary
Secondary
Leukaemia Other Serious 5/1/2008 66 Male 10/28/2008 Physician Japan
Primary
Concomitant
Unrelated Donor Bone Marrow Transplantation Therapy Death 1/1/2007 56 Female 10/27/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Leukaemia Other Serious 5/10/2008 69 Male 11/25/2008 Physician Japan
Primary
Concomitant
Hyperammonaemic Encephalopathy Death 69 Male 12/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Alkalosis Death 69 Male 12/12/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 6/1/2008 Female 12/24/2008 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/8/2008 Male 12/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Alkalosis Death 69 Male 1/9/2009 Physician Australia
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Death 1/1/2005 69 Male 1/29/2009 Other Health Professional Australia
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 59 Female 4/22/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 2/3/2009 20 Male 4/28/2009 Consumer France
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious Female 105 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/1/2009 Female 5/19/2009 Pharmacist Australia
Primary
Concomitant
No Therapeutic Response Death 16 Female 6/15/2009 Other Health Professional China
Primary
Concomitant
Thrombocytopenia Other Serious 6/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/16/2009 81 Female 98 lb 6/23/2009 Pharmacist United States
Primary
Secondary
Staphylococcal Infection Other Serious 1/1/2008 43 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Pneumonia Other Serious 52 Male 8/13/2009 Consumer Poland
Primary
Concomitant
Thrombosis Death 7/5/2009 Female 8/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/1/2009 Female 8/24/2009 Pharmacist Australia
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/16/2009 Other Health Professional United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/14/2009 Other Health Professional United States
Primary
Secondary
Nausea Other Serious 12/16/2008 56 Female 9/16/2009 Other Health Professional Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 6/1/2008 59 Female 9/25/2009 Other Health Professional United States
Primary
Secondary
Thrombosis Death 7/5/2009 Female 10/9/2009 Pharmacist United Kingdom
Primary
Concomitant
Treatment Failure Other Serious 11/13/2009 Consumer United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2006 Male 12/10/2009 Consumer United Kingdom
Primary
Secondary
Neutropenia Other Serious 42 Male 12/11/2009 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 8/20/2009 Male 196 lb 12/17/2009 Physician United Kingdom
Primary
Secondary
Nausea Other Serious 12/16/2008 56 Female 12/15/2009 Other Health Professional Japan
Primary
Concomitant
Thrombosis Other Serious 7/5/2009 Female 168 lb 1/15/2010 Pharmacist France
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/25/2010 Other Health Professional Japan
Primary
Concomitant
Pneumonitis Other Serious 9/19/2009 Male 3/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Other Serious 8/9/2009 Male 3/30/2010 Physician Norway
Primary
Secondary
Concomitant
Pneumonitis Other Serious 8/9/2009 70 Male 4/1/2010 Physician Norway
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2/1/2009 56 Male 3/31/2010 Other Health Professional Japan
Primary
Concomitant
Pneumonitis Other Serious Male 4/7/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2007 56 Male 4/22/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Pneumonitis Other Serious Male 4/22/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2007 56 Male 4/26/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Drug Ineffective For Unapproved Indication Death 45 Male 6/10/2010 Italy
Primary
Concomitant
Cardiomyopathy Other Serious 6/25/2010 Physician Italy
Primary
Secondary
Idiosyncratic Drug Reaction Death 12/18/2008 81 Female 132 lb 8/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Idiosyncratic Drug Reaction Death 12/18/2008 81 Female 8/27/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatitis B Other Serious 57 Female 9/9/2010 Other Health Professional Turkey
Primary
Secondary
Hepatitis B Other Serious 57 Female 9/28/2010 Physician Turkey
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 67 Female 10/8/2010 Physician Japan
Primary
Concomitant
Hepatitis B Hospitalization 1/1/2010 57 Female 10/15/2010 Other Health Professional Turkey
Primary
Secondary
Asthma Other Serious 11/8/2010 Physician Germany
Primary
Secondary
Concomitant
Arthritis Other Serious 11/10/2010 Physician Germany
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 11/12/2010 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/25/2009 59 Male 11/4/2010 Other Health Professional Japan
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/1/2008 27 Male 11/21/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 5/1/2008 27 Male 11/30/2010
Primary
Secondary
Pneumatosis Intestinalis Other Serious 12/2/2009 61 Male 12/1/2010 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 12/2/2009 61 Male 139 lb 1/6/2011 Other Health Professional Japan
Primary
Concomitant
Acute Promyelocytic Leukaemia Other Serious 1/1/2004 72 Male 1/26/2011 Consumer United Kingdom
Primary
Secondary
Drug Interaction Hospitalization 8/9/2009 70 Male 2/7/2011 Physician Norway
Primary
Secondary
Concomitant
Interacting
Myelodysplastic Syndrome Death 53 Male 2/7/2011 Other Health Professional Australia
Primary
Secondary
Myocardial Infarction Hospitalization 70 2/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Death 8/9/2009 70 Male 2/10/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 8/9/2009 70 Male 2/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Other Serious 8/9/2009 70 Male 2/25/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization Male 3/4/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Hepatitis B Other Serious 3/25/2011 Other Health Professional Japan
Primary
Secondary
Pneumonitis Other Serious 8/9/2009 70 Male 3/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fluid Retention Other Serious 51 Male 4/1/2011 Other Health Professional Japan
Primary
Concomitant
Brain Natriuretic Peptide Increased Disability 51 Male 4/15/2011 Other Health Professional Japan
Primary
Concomitant
Acute Myeloid Leukaemia Death 54 Male 4/20/2011 Other Health Professional Germany
Primary
Concomitant
Amino Acid Level Increased Other Serious 20 Male 4/21/2011 Other Health Professional France
Primary
Secondary
Herpes Zoster Hospitalization 2/28/2009 59 Male 141 lb 6/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 8/19/2011 Consumer United Kingdom
Primary
Secondary
Constipation Hospitalization Male 8/29/2011 Lawyer United States
Primary
Concomitant
Pneumonia Death 4 Male 9/7/2011 Other Health Professional China
Primary
Secondary
Aortic Aneurysm Other Serious 11/1/2008 83 Male 9/21/2011 Lawyer United States
Primary
Concomitant
Dyspnoea Hospitalization 9/12/2011 31 Male 10/3/2011 Other Health Professional China
Primary
Concomitant
Vision Blurred Death 9/12/2011 31 Male 128 lb 10/3/2011 Physician China
Primary
Concomitant
Autoimmune Disorder Other Serious 42 Male 10/17/2011 Other Health Professional Greece
Primary
Secondary
Deep Vein Thrombosis Hospitalization 11/1/2008 83 Male 11/10/2011 Lawyer United States
Primary
Concomitant
Congestive Cardiomyopathy Hospitalization 50 Female 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/1/2008 83 Male 1/30/2012 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious Female 1/30/2012 Other Health Professional United States
Primary
Secondary
Rash Hospitalization Female 1/30/2012 Physician United States
Primary
Secondary
Cardiac Failure Congestive Other Serious Female 1/31/2012 Other Health Professional United States
Primary
Secondary
Cardiac Failure Congestive Other Serious Female 1/29/2012 Other Health Professional United States
Primary
Secondary
Cardiac Failure Congestive Other Serious Female 1/29/2012 Other Health Professional United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 59 Male 1/31/2012 Other Health Professional Latvia
Primary
Secondary
Cardiac Failure Congestive Other Serious Female 1/30/2012 Other Health Professional United States
Primary
Secondary
Cardiac Failure Congestive Other Serious 50 Female 2/14/2012 Physician United States
Primary
Secondary
Fatigue Death 11/1/2008 83 Male 2/20/2012 Physician United States
Primary
Concomitant
Bile Duct Cancer Hospitalization 50 Female 2/28/2012 Physician United States
Primary
Concomitant
Back Pain Hospitalization 11/1/2008 83 Male 3/22/2012 Consumer United States
Primary
Concomitant
Fungal Sepsis Other Serious 3/26/2012 Other Health Professional China
Primary
Secondary
Concomitant
Cardiac Failure Death 3/29/2012 Other Health Professional Sweden
Primary
Secondary
Cardiac Failure Death 3/29/2012 Other Health Professional Sweden
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 54 Male 4/4/2012 Other Health Professional Serbia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 54 Male 4/4/2012 Other Health Professional Serbia
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 54 Male 4/13/2012 Other Health Professional Serbia
Primary
Secondary
Cardiac Failure Death 4/16/2012 Other Health Professional Sweden
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 54 Male 4/10/2012 Other Health Professional Serbia
Primary
Secondary
Acute Myeloid Leukaemia Death 54 Male 4/24/2012 Other Health Professional Serbia
Primary
Secondary
Abdominal Distension Other Serious 11/1/2008 83 Male 4/30/2012 Consumer United States
Primary
Concomitant
Myelodysplastic Syndrome Life Threatening 10/27/2009 70 Female 5/11/2012 Physician Japan
Primary
Secondary
Cytogenetic Abnormality Death 58 Female 5/24/2012 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 6/12/2012 Other Health Professional Italy
Primary
Secondary
Refusal Of Treatment By Patient Other Serious 20 Female 6/29/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/11/2011 56 Male 10/26/2012 Physician De
Primary
Secondary
Concomitant
Visceral Leishmaniasis Death 72 Female 9/10/2012 Other Health Professional Country Not Specified
Primary
Concomitant

Drug Data