Mesna combined with Vincristine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tongue Disorder Other Serious 12/5/2005 Male 216 lb 12/27/2005 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 11/23/2005 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Life Threatening 3/27/2006 Female 116 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious Male 5/12/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/7/2006 70 Female 5/12/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 42 Male 9/15/2006 Spain
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/9/2005 Male 164 lb 10/5/2006 Physician Australia
Primary
Concomitant
Pancreatitis Acute Other Serious 10/11/2006 65 Male 196 lb 11/3/2006 Physician Australia
Primary
Secondary
Pancreatitis Acute Other Serious 10/11/2006 65 Male 196 lb 12/7/2006 Physician Australia
Primary
Secondary
Sepsis Death 1/14/2007 Female 14 lb 1/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia 1/1/2006 31 Male 3/28/2007 Physician United States
Primary
Concomitant
Skin Reaction Other Serious 2/23/2007 Male 165 lb 4/30/2007 Physician Germany
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 15 Male 77 lb 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/9/2007 5 Male 33 lb 7/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Stem Cell Transplant Death 6/25/2007 Male 40 lb 7/3/2007 Physician United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 3 Male 35 lb 8/28/2007
Primary
Secondary
Urinary Tract Infection Other Serious 21 Female 9/5/2007 Other Health Professional United States
Primary
Secondary
Nephrogenic Systemic Fibrosis Death 1/1/2004 15 Male 77 lb 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 21 Female 8/16/2007 Physician United States
Primary
Secondary
Sepsis Neonatal Hospitalization Male 8/16/2007 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 54 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 61 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 79 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Disability 1/11/2006 60 Female 231 lb 10/1/2007 Physician France
Primary
Secondary
Concomitant
Drug Toxicity Death Unknown 10/30/2007 France
Primary
Secondary
Drug Toxicity Death Unknown 10/30/2007 France
Primary
Secondary
Somnolence Death 12/19/2007 Male 176 lb 2/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Generalised Erythema Other Serious 11/14/2007 Female 132 lb 3/10/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia 1/1/2006 31 Male 3/28/2008 Physician United States
Primary
Concomitant
Ventricular Fibrillation Death 1/1/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 4/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 5/5/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 4/16/2008 52 Male 157 lb 5/21/2008 Physician Malaysia
Primary
Concomitant
Ureteric Dilatation Other Serious 14 Male 5/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Haematuria Other Serious 14 Male 6/12/2008 United Kingdom
Primary
Secondary
Concomitant
Haematuria Other Serious 1/1/2008 14 Male 6/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 5/1/2008 14 Male 143 lb 6/19/2008 Consumer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Telangiectasia Other Serious 14 Male 6/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Disorder Disability 5/13/2006 Male 6/23/2008 Consumer Germany
Primary
Secondary
Concomitant
Nocturia Life Threatening 14 Male 6/16/2008 United Kingdom
Primary
Secondary
Concomitant
Haematuria Other Serious 14 Male 6/26/2008 United Kingdom
Primary
Concomitant
Neurotoxicity Life Threatening 1/1/2007 37 Male 7/28/2008 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 1/13/2006 59 Female 8/5/2008 France
Primary
Secondary
Concomitant
Thrombosis Other Serious 7/12/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/25/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/13/2007 59 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 4/27/2008 16 Male 129 lb 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/1/2008 14 Male 143 lb 9/26/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 10/13/2008 Physician United Kingdom
Primary
Secondary
Death Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Renal Failure Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Neutropenic Sepsis Death 10/13/2008 Physician United Kingdom
Primary
Secondary
Pancreatitis Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Neurotoxicity Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Renal Impairment Life Threatening 8/17/2008 60 Male 10/9/2008 Israel
Primary
Secondary
Renal Failure Acute Hospitalization 10/2/2008 64 Female 10/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/1/2007 43 Male 10/7/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/1/2007 56 Male 10/7/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/1/2007 53 Male 10/7/2008 Physician United States
Primary
Concomitant
Neurotoxicity Other Serious 10/28/2008 Physician United Kingdom
Primary
Secondary
Neutropenic Sepsis Death 10/28/2008 Physician United Kingdom
Primary
Secondary
Death Other Serious 10/29/2008 Physician United Kingdom
Primary
Secondary
Sinusitis Other Serious 7/1/2008 61 Female 12/3/2008 Consumer United Kingdom
Primary
Concomitant
Sinusitis Other Serious 7/1/2008 61 Female 12/9/2008 Consumer United Kingdom
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Encephalopathy Other Serious 12/16/2008 33 Male 2/6/2009 Physician Norway
Primary
Secondary
Concomitant
Clostridium Difficile Colitis 22 Female 2/19/2009 Other Health Professional United States
Primary
Concomitant
Encephalopathy Other Serious 12/16/2008 33 Male 2/25/2009 Physician Norway
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 1/27/2009 Female 3/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Encephalopathy Other Serious 12/16/2008 3/6/2009 Physician Norway
Primary
Secondary
Concomitant
Confusional State Other Serious 12/16/2008 33 Male 3/6/2009 Physician Netherlands
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/25/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 7/12/2007 59 Female 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Encephalopathy Other Serious 12/16/2008 3/31/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 1/5/2009 1 Female 15 lb 3/30/2009 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/16/2009 Female 4/3/2009 Physician Germany
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/13/2007 59 Female 4/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 1/16/2009 Female 5/7/2009 Physician Germany
Primary
Concomitant
Pulmonary Embolism Death 4/3/2009 71 Male 159 lb 5/11/2009 Physician Germany
Primary
Concomitant
Lactobacillus Infection Hospitalization 5/3/2009 1 Male 5/15/2009 Physician
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/1/2008 14 Male 205 lb 5/29/2009 Other Health Professional France
Primary
Secondary
Concomitant
Lactobacillus Infection Hospitalization 5/3/2009 1 Male 20 lb 6/1/2009 Physician United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 5/1/2008 Male 205 lb 6/2/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/3/2009 71 Male 159 lb 6/16/2009 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 6/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Pneumonia Hospitalization 1/10/2009 Female 6/19/2009 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 1/10/2009 Female 6/25/2009 Physician Germany
Primary
Concomitant
Pulmonary Embolism Death 4/3/2009 71 Male 159 lb 7/10/2009 Physician Germany
Primary
Concomitant
Encephalopathy Other Serious 12/16/2008 33 7/10/2009 Pharmacist Norway
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1 Male 7/24/2009 Other Health Professional Lebanon
Primary
Secondary
Wound Other Serious 1/1/2004 8/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 7/27/2008 13 Male 134 lb 8/5/2009 Pharmacist Belgium
Primary
Secondary
Concomitant
Osteonecrosis Disability 3/1/2008 Male 8/12/2009 Other Health Professional Italy
Primary
Concomitant
Restlessness Other Serious 33 Male 9/10/2009 Other Health Professional Norway
Primary
Secondary
Epilepsy Other Serious 15 Female 9/11/2009 Other Health Professional Norway
Primary
Secondary
Rash Hospitalization 1/27/2009 Female 9/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 9 Male 9/17/2009
Primary
Secondary
Osteonecrosis Disability 3/1/2008 Male 9/17/2009 Other Health Professional Italy
Primary
Concomitant
Rash Hospitalization 1/27/2009 Female 10/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Personality Change Required Intervention 12/23/2008 Female 90 lb 8/29/2009 Pharmacist United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/4/2009 Male 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Virus Infection Hospitalization 10/17/2009 Male 1/4/2010 Physician Italy
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/22/2009 Male 1/4/2010 Physician Italy
Primary
Secondary
Concomitant
Somnolence Other Serious 1/11/2010 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 7/5/2009 Female 168 lb 1/15/2010 Pharmacist France
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/13/2010 Male 148 lb 2/9/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 3/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Varicella Other Serious Male 3/10/2010 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/1/2006 Male 3/10/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious Male 3/15/2010 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 9/1/2006 Male 3/15/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Infection Other Serious Male 4/20/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 4/23/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2006 22 Male 4/23/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2006 22 Male 4/27/2010 United States
Primary
Secondary
Concomitant
Uterine Enlargement Other Serious 32 Female 5/6/2010 Physician Greece
Primary
Secondary
Venoocclusive Liver Disease Hospitalization 14 Male 5/19/2010
Primary
Secondary
White Blood Cell Count Increased Other Serious 9/1/2006 22 Male 5/21/2010 United States
Primary
Secondary
Concomitant
Uterine Enlargement Other Serious 32 Female 5/27/2010 Physician Greece
Primary
Secondary
Uterine Enlargement Other Serious 32 Female 5/28/2010 Physician Greece
Primary
Secondary
White Blood Cell Count Increased Other Serious 9/1/2006 22 Male 6/9/2010 United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 7/27/2008 13 Male 6/6/2010 Belgium
Primary
Secondary
Concomitant
Pleural Effusion Death 6/2/2010 Female 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 6/15/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2006 22 Male 6/16/2010 United States
Primary
Secondary
Concomitant
Respiratory Failure Death 6/2/2010 Female 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Febrile Neutropenia Other Serious 6/25/2010 48 Male 7/6/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2006 22 Male 170 lb 7/21/2010 United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2006 22 Male 170 lb 9/2/2010 United States
Primary
Secondary
Concomitant
Death Hospitalization 9/13/2010 76 Female 148 lb 9/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 9/13/2010 76 Female 148 lb 10/5/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 10/11/2010 Lawyer United States
Primary
Concomitant

Drug Data